CN1403119A - Medicine for treating cerebral thrombus and its prepn - Google Patents
Medicine for treating cerebral thrombus and its prepn Download PDFInfo
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- CN1403119A CN1403119A CN02133228A CN02133228A CN1403119A CN 1403119 A CN1403119 A CN 1403119A CN 02133228 A CN02133228 A CN 02133228A CN 02133228 A CN02133228 A CN 02133228A CN 1403119 A CN1403119 A CN 1403119A
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Abstract
The present invention relates to one kind of Chinese medicine preparation, and is one kind of medicine for treating cerebral thrombus and its preparation. Ten kinds of Chinese medicinal materials including notoginseng, kudzuvine root, red peony root, safflower, dragon's blood, etc. are prepared into caspule through separate crushing, alcohol extraction, decoction, filtering, concentration, merging, drying, capsulizing and other steps.
Description
Technical field: the present invention relates to a kind of Chinese medicine preparation, promptly a kind of brain bolt rehabilitation medicine and preparation method for the treatment of cerebral thrombosis disease.
Background technology: in prior art, for the disease of cerebrovascular aspect, at present common have cerebrovascular sclerosis, narrow, thromboembolism, wind among the traditional Chinese medical science is referred to as again.Because growth in the living standard, the raising of industrial and agricultural production level, people participate in blue-collar minimizing directly, cause a large amount of increase of disease of cardiovascular and cerebrovascular vessel, so paid attention to very much in research aspect this, about the report and medicine also a lot, many kinds such as, XINNAOKANG logical, Moschus antithrombotic pill, XUESHUANXINMAINING capsule such as BUCHANG NAOXINTONG JIAONANG, brain plug, this does not also comprise many hospital internal preparations, be the medicine of this aspect disease of treatment, in numerous similar medicines and the invention declared, identical with present technique finds as yet.
Summary of the invention: the objective of the invention is to provide at above-mentioned situation a kind of evident in efficacy, technology is reasonable, especially the rehabilitation that promotes apoplexy sequela is had the brain bolt rehabilitation medicine and the preparation method of the treatment cerebral thrombosis disease of significant curative effect.
Technical solution of the present invention is: a kind of brain bolt rehabilitation medicine for the treatment of cerebral thrombosis disease, it is made by the following raw materials in weight material: Radix Notoginseng 120-180g, Radix Puerariae 96-144g, Radix Paeoniae Rubra 80-120g, Flos Carthami 80-120g, Herba Siegesbeckiae 80-120g, Sanguis Draxonis 64-96g, Rhizoma Chuanxiong 64-96g, Pheretima 40-60g, Hirudo 40-60g, Radix Achyranthis Bidentatae 40-60g.Preferably make capsule.Each medicinal component also can be mixed and made into common dosage forms in the pharmacy such as tablet, pill, electuary, oral liquid, granule with pharmaceutical carrier or additive.
Apoplexy is thought because of caused by energy stagnation and blood stasis in the traditional Chinese medical science.We are according to the principle of " control wind and control blood earlier, blood sector-style from go out ", and are first with Radix Notoginseng, the Hirudo removing blood stasis of going ahead of the rest, eliminating stagnation; Sensible with circulation of qi promoting such as Rhizoma Chuanxiong, Herba Siegesbeckiaes; With Radix Paeoniae Rubra, Flos Carthami, Sanguis Draxonis promoting blood circulation to remove blood stasis; Use the Radix Puerariae expelling pathogenic factors from muscles, invigorating YANG QI to promote eruption; With the Radix Achyranthis Bidentatae conducting blood to flow downwards; Make the Pheretima clearing heat for calming endogenous wind, water side by side stasis of blood poison in external.So we are fit to the various diseases of apoplexy fully, and it can be captured step by step.
Preparation method: Radix Notoginseng, Sanguis Draxonis powder is broken into fine powder, and Radix Puerariae adds 4 times of amount 80% alcohol reflux 3 times, each 1.5 hours, merge extractive liquid, filters filtrate recycling ethanol, be condensed into thick paste, medicinal residues add residue 7 flavors and merge, and decoct with water 3 times, 3 hours for the first time, 2 hours for the second time, 1 hour for the third time, collecting decoction filters, and filtrate is concentrated into flowing soaking paste, add ethanol and make and contain alcohol 60%, fully stir cold preservation 48 hours, filter, filtrate recycling ethanol is concentrated into thick paste, merge with the Radix Puerariae ethanol extraction, drying under reduced pressure is ground into fine powder, adds Radix Notoginseng, fine powder of dragons blood, mixing, encapsulated.
Function cures mainly: blood circulation promoting and blood stasis dispelling, dredge the meridian passage.Be used for that apoplexy, apoplex involving the channels and collaterals, stiffness of the tongue language due to the obstruction of collaterals by blood stasis is puckery, facial hemiparalysis, hemiplegia.
Usage and dosage: with the capsule is example, oral, a 3-4 grain (0.3g), 3 times on the one.
Advantage of the present invention is: 1, toxic and side effects of the present invention is little, and pharmacologically active is strong, but blood viscosity lowering is accelerated blood flow rate, the thrombus model animal is had tangible anti-thrombosis function, and obvious blood fat reducing, blood pressure lowering and antiatherogenic effect are arranged.2, through Jilin Prov. Traditional Chiense Medical College 150 routine stroke patient clinical observations are shown, total effective rate 86.6%, curative effect is obvious, especially to promoting the rehabilitation highly significant of apoplexy sequela, has no adverse reaction, and is clinical safe in utilization.3, reasonable, the science, stable of technology.
Below in conjunction with embodiment the present invention is described in further detail:
The specific embodiment:
Embodiment 1: NAOSHUAN KANGFU JIAONANG is made by the following raw materials in weight material: Radix Notoginseng 150g, Radix Puerariae 120g, Radix Paeoniae Rubra 100g, Flos Carthami 100g, Herba Siegesbeckiae 100g, Sanguis Draxonis 80g, Rhizoma Chuanxiong 80g, Pheretima 50g, Hirudo 50g, Radix Achyranthis Bidentatae 50g.
Embodiment 2: NAOSHUAN KANGFU JIAONANG is made by the following raw materials in weight material: Radix Notoginseng 120g, Radix Puerariae 130g, Radix Paeoniae Rubra 120g, Flos Carthami 120g, Herba Siegesbeckiae 120g, Sanguis Draxonis 70g, Rhizoma Chuanxiong 90g, Pheretima 60g, Hirudo 60g, Radix Achyranthis Bidentatae 60g.
Embodiment 3: preparation method: (1) raw material: Radix Notoginseng 150g, Radix Puerariae 120g, Radix Paeoniae Rubra 100g, Flos Carthami 100g, Herba Siegesbeckiae 100g, Sanguis Draxonis 80g, Rhizoma Chuanxiong 80g, Pheretima 50g, Hirudo 50g, Radix Achyranthis Bidentatae 50g.(2) technology: Radix Notoginseng, Sanguis Draxonis powder is broken into fine powder, and Radix Puerariae adds 4 times of amount 80% alcohol reflux 3 times, each 1.5 hours, merge extractive liquid, filters filtrate recycling ethanol, be condensed into thick paste, medicinal residues add residue 7 flavors and merge, and decoct with water 3 times, 3 hours for the first time, 2 hours for the second time, 1 hour for the third time, collecting decoction filters, and filtrate is concentrated into flowing soaking paste, add ethanol and make and contain 60%, fully stir cold preservation 48 hours, filter, filtrate recycling ethanol is concentrated into thick paste, merge with the Radix Puerariae ethanol extraction, drying under reduced pressure is ground into fine powder, add Radix Notoginseng, fine powder of dragons blood, mixing, encapsulated, make 1000 promptly.
Claims (5)
1, a kind of brain bolt rehabilitation medicine for the treatment of cerebral thrombosis disease is characterized in that it is made by the following raw materials in weight material: Radix Notoginseng 120-180g, Radix Puerariae 96-144g, Radix Paeoniae Rubra 80-120g, Flos Carthami 80-120g, Herba Siegesbeckiae 80-120g, Sanguis Draxonis 64-96g, Rhizoma Chuanxiong 64-96g, Pheretima 40-60g, Hirudo 40-60g, Radix Achyranthis Bidentatae 40-60g.
2, according to the brain bolt rehabilitation medicine of the described treatment cerebral thrombosis disease of claim 1, it is characterized in that making capsule.
3, according to the brain bolt rehabilitation medicine of the described treatment cerebral thrombosis disease of claim 2, it is characterized in that optimization formula is: Radix Notoginseng 150g, Radix Puerariae 120g, Radix Paeoniae Rubra 100g, Flos Carthami 100g, Herba Siegesbeckiae 100g, Sanguis Draxonis 80g, Rhizoma Chuanxiong 80g, Pheretima 50g, Hirudo 50g, Radix Achyranthis Bidentatae 50g.
4,, it is characterized in that each medicinal component also can be mixed and made into common dosage forms in the pharmacy such as tablet, pill, electuary, oral liquid, granule with pharmaceutical carrier or additive according to the brain bolt rehabilitation medicine of the described treatment cerebral thrombosis disease of claim 1.
5, a kind of preparation method for preparing the described brain bolt of claim 2 rehabilitation medicine is characterized in that method for making is as follows: Radix Notoginseng, Sanguis Draxonis powder is broken into fine powder, and Radix Puerariae adds 4 times of amount 80% alcohol reflux 3 times, each 1.5 hours, merge extractive liquid, filtered, filtrate recycling ethanol is condensed into thick paste, and medicinal residues add residue 7 flavors and merge, decoct with water 3 times, 3 hours for the first time, 2 hours for the second time, 1 hour for the third time, collecting decoction filters, and filtrate is concentrated into flowing soaking paste, add ethanol make contain alcohol 60%, fully stir, cold preservation 48 hours filters, filtrate recycling ethanol, be concentrated into thick paste, merge drying under reduced pressure with the Radix Puerariae ethanol extraction, be ground into fine powder, add Radix Notoginseng, fine powder of dragons blood, mixing, encapsulated.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021332282A CN1180821C (en) | 2002-10-18 | 2002-10-18 | Medicine for treating cerebral thrombus and its prepn |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021332282A CN1180821C (en) | 2002-10-18 | 2002-10-18 | Medicine for treating cerebral thrombus and its prepn |
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| Publication Number | Publication Date |
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| CN1403119A true CN1403119A (en) | 2003-03-19 |
| CN1180821C CN1180821C (en) | 2004-12-22 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB021332282A Expired - Lifetime CN1180821C (en) | 2002-10-18 | 2002-10-18 | Medicine for treating cerebral thrombus and its prepn |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100420454C (en) * | 2006-05-29 | 2008-09-24 | 通化衛京药业股份有限公司 | Pharmaceutical composition for treating apoplexy and preparation method thereof |
| CN102526158A (en) * | 2012-01-17 | 2012-07-04 | 张昕 | Chinese medicine for treating thrombus |
| CN102824498A (en) * | 2012-09-18 | 2012-12-19 | 南京正亮医药科技有限公司 | Application of Yinao Fujian capsule in preparing medicines for treating vasculitis |
| CN104435045A (en) * | 2014-12-25 | 2015-03-25 | 通化卫京药业股份有限公司 | Traditional Chinese medicine composition for treating stroke and sequela thereof and preparation method thereof |
| CN105381170A (en) * | 2015-12-16 | 2016-03-09 | 吉林省长源药业有限公司 | Traditional Chinese medicinal composition as well as preparation method and application thereof |
| CN112220877A (en) * | 2020-11-13 | 2021-01-15 | 吉林省第二荣复军人医院 | Traditional Chinese medicine preparation for treating cerebral apoplexy in convalescent period and preparation method thereof |
-
2002
- 2002-10-18 CN CNB021332282A patent/CN1180821C/en not_active Expired - Lifetime
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100420454C (en) * | 2006-05-29 | 2008-09-24 | 通化衛京药业股份有限公司 | Pharmaceutical composition for treating apoplexy and preparation method thereof |
| CN102526158A (en) * | 2012-01-17 | 2012-07-04 | 张昕 | Chinese medicine for treating thrombus |
| CN102824498A (en) * | 2012-09-18 | 2012-12-19 | 南京正亮医药科技有限公司 | Application of Yinao Fujian capsule in preparing medicines for treating vasculitis |
| CN104435045A (en) * | 2014-12-25 | 2015-03-25 | 通化卫京药业股份有限公司 | Traditional Chinese medicine composition for treating stroke and sequela thereof and preparation method thereof |
| CN105381170A (en) * | 2015-12-16 | 2016-03-09 | 吉林省长源药业有限公司 | Traditional Chinese medicinal composition as well as preparation method and application thereof |
| CN112220877A (en) * | 2020-11-13 | 2021-01-15 | 吉林省第二荣复军人医院 | Traditional Chinese medicine preparation for treating cerebral apoplexy in convalescent period and preparation method thereof |
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| Publication number | Publication date |
|---|---|
| CN1180821C (en) | 2004-12-22 |
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