CN1299411A - 用于基因治疗的高温诱导表达载体及其使用方法 - Google Patents

用于基因治疗的高温诱导表达载体及其使用方法 Download PDF

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CN1299411A
CN1299411A CN98812752A CN98812752A CN1299411A CN 1299411 A CN1299411 A CN 1299411A CN 98812752 A CN98812752 A CN 98812752A CN 98812752 A CN98812752 A CN 98812752A CN 1299411 A CN1299411 A CN 1299411A
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cell
feature
expression
promotor
gene
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Chinese (zh)
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汤姆·昌
尤金·W·格尔纳
大卫·T·哈里斯
伊万·赫什
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University of Arizona
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University of Arizona
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/001Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
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    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/80Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85Vector systems having a special element relevant for transcription from vertebrates mammalian
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    • C12N2840/00Vectors comprising a special translation-regulating system
    • C12N2840/20Vectors comprising a special translation-regulating system translation of more than one cistron

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  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN98812752A 1997-11-03 1998-11-03 用于基因治疗的高温诱导表达载体及其使用方法 Pending CN1299411A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6408897P 1997-11-03 1997-11-03
US60/064,088 1997-11-03

Publications (1)

Publication Number Publication Date
CN1299411A true CN1299411A (zh) 2001-06-13

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ID=22053477

Family Applications (1)

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CN98812752A Pending CN1299411A (zh) 1997-11-03 1998-11-03 用于基因治疗的高温诱导表达载体及其使用方法

Country Status (9)

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EP (1) EP1029041A2 (ja)
JP (1) JP2001521740A (ja)
KR (1) KR20010031762A (ja)
CN (1) CN1299411A (ja)
AU (1) AU1377299A (ja)
BR (1) BR9813917A (ja)
CA (1) CA2308575A1 (ja)
IL (1) IL135943A0 (ja)
WO (1) WO1999023216A2 (ja)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103667345A (zh) * 2013-12-02 2014-03-26 东南大学 一种抗肿瘤基因磁性复合纳米颗粒及制备方法
WO2017133633A1 (en) * 2016-02-04 2017-08-10 Nanjing Legend Biotech Co., Ltd. Engineered mammalian cells for cancer therapy
CN108913661A (zh) * 2018-06-22 2018-11-30 安徽 一种人体研究用造血干细胞的制备和提取方法
WO2022067875A1 (zh) * 2020-09-29 2022-04-07 中国农业科学院生物技术研究所 一种作物高温响应型基因组精准甲基化调控回路
CN116536349A (zh) * 2023-05-22 2023-08-04 安徽农业大学 一种大豆GmMLP34基因在调控植物耐高温性上的应用

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19951765A1 (de) * 1999-10-27 2001-05-03 Thomas Schweder Wirts-Vektor-Systeme zur Überproduktion von thermolabilen Enzymen psychrophiler Organismen
US6579522B1 (en) 2000-06-27 2003-06-17 Genvec, Inc. Replication deficient adenoviral TNF vector
US7285414B2 (en) 2000-09-26 2007-10-23 Emory University Viruses targeted to hypoxic cells and tissues
ATE418342T1 (de) * 2000-09-26 2009-01-15 Univ Emory Viren gegen hypoxische zellen und gewebe
US20030086903A1 (en) 2001-11-02 2003-05-08 Genvec, Inc. Therapeutic regimen for treating cancer
SI1541674T1 (sl) 2002-06-18 2011-04-29 Eisai R&D Man Co Ltd Primarno kultivirani adipociti za gensko terapijo
AU2003278079A1 (en) * 2002-10-14 2004-05-04 Develogen Aktiengesellschaft Fur Entwicklungsbiologische Forschung Proteins involved in the regulation of energy homeostasis
JP2008048601A (ja) * 2004-06-15 2008-03-06 Nippon Kosei Kagaku Kenkyusho:Kk 治療に有用な産物の生産法およびシステム
JP2008540347A (ja) * 2005-05-03 2008-11-20 フェテリネールメディツィニシュ ウニベルジテート ウィーン 浸透性カプセル
NZ584848A (en) * 2007-09-28 2012-09-28 Intrexon Corp Therapeutic gene-switch constructs and bioreactors for the expression of biotherapeutic molecules, and uses thereof
IT202200000788A1 (it) * 2022-01-19 2023-07-19 Bruno Cell S R L Induzione sensibile alla temperatura del programma miogenico e/o adipogenico in cellule per la produzione di tessuto muscolare e/o adiposo

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3991770A (en) * 1974-01-24 1976-11-16 Leveen Harry H Method for treating benign and malignant tumors utilizing radio frequency, electromagnetic radiation
EP0299127A1 (en) * 1987-07-16 1989-01-18 IntraCel Corporation A method for the expression of recombinant genes under stimulation from an inducively expressed activator protein
EP0455424A3 (en) * 1990-05-02 1992-04-29 Merck & Co. Inc. Mammalian inducible promoter cascade system
FR2717187B1 (fr) * 1994-03-10 1996-05-31 Transgene Sa Usage combiné de deux cassettes d'expression pour la production d'une protéine d'intérêt.

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103667345A (zh) * 2013-12-02 2014-03-26 东南大学 一种抗肿瘤基因磁性复合纳米颗粒及制备方法
WO2017133633A1 (en) * 2016-02-04 2017-08-10 Nanjing Legend Biotech Co., Ltd. Engineered mammalian cells for cancer therapy
CN108883202A (zh) * 2016-02-04 2018-11-23 南京传奇生物科技有限公司 用于癌症治疗的工程化的哺乳动物细胞
CN108913661A (zh) * 2018-06-22 2018-11-30 安徽 一种人体研究用造血干细胞的制备和提取方法
WO2022067875A1 (zh) * 2020-09-29 2022-04-07 中国农业科学院生物技术研究所 一种作物高温响应型基因组精准甲基化调控回路
CN116536349A (zh) * 2023-05-22 2023-08-04 安徽农业大学 一种大豆GmMLP34基因在调控植物耐高温性上的应用
CN116536349B (zh) * 2023-05-22 2024-02-20 安徽农业大学 一种大豆GmMLP34基因在调控植物耐高温性上的应用

Also Published As

Publication number Publication date
IL135943A0 (en) 2001-05-20
EP1029041A2 (en) 2000-08-23
JP2001521740A (ja) 2001-11-13
KR20010031762A (ko) 2001-04-16
BR9813917A (pt) 2001-10-30
WO1999023216A2 (en) 1999-05-14
CA2308575A1 (en) 1999-05-14
AU1377299A (en) 1999-05-24
WO1999023216A3 (en) 1999-08-05

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