CN1293914C - Health care medicinal composition for improving sleeping and preparation preocess thereof - Google Patents
Health care medicinal composition for improving sleeping and preparation preocess thereof Download PDFInfo
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- CN1293914C CN1293914C CN 02139459 CN02139459A CN1293914C CN 1293914 C CN1293914 C CN 1293914C CN 02139459 CN02139459 CN 02139459 CN 02139459 A CN02139459 A CN 02139459A CN 1293914 C CN1293914 C CN 1293914C
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Abstract
The present invention relates to a health care drug composition for improving sleep. Any pharmaceutics medicament form is prepared from clove, nutmeg, cinnamon, asafoetida, rhizoma kaempferiae and black pepper with a well-known formulation method. The present invention has the action of tranquilizing the mind, nourishing the heart and improving the sleep.
Description
Technical field
The present invention relates to a kind of health medicine preparation of compositions technology of improving sleep quality.
Background technology
The Western medicine of Cure for insomnia is generally several classes such as antianxiety drugs, sedative hypnotic, beta-blocker and bromide, and untoward reaction is more serious, as has excessive abirritative phenomenon; Easily produce drug resistance, dependency and certain toxicity is arranged.The Chinese medicine health care product of the improvement of development sleep at present, wherein 80% prescription has melatonin, studies show that, and melatonin is when improving sleep, and the incidence rate of convulsions increases.Tibetan medicine has theory in several thousand and medication practice, and the compound preparation of Tibetan medicine has distinctive feature clinically, and the effectiveness of its practice is by for many years clinical the proof.
Summary of the invention
The objective of the invention is for a kind of health medicine compositions of calming the nerves and nourishing heart, improving the sleep effect that has is provided.
Another object of the present invention is for a kind of improvement sleep health medicine preparation of compositions technology is provided.
Purpose of the present invention can realize by following measure:
A kind of health medicine preparation of compositions technology of improving sleep comprises the steps: that (1) press the weight percentage preparation health composition of raw material Flos Caryophylli 10-40%, Semen Myristicae 10-40%, Cortex Cinnamomi 10-20%, Resina Ferulae 20-40%, Rhizoma Kaempferiae 10-30%, black pepper 10-30% and pulverize; (2) raw material of pulverizing is carried out CO under pressure 25-35Mpa, temperature 30-50 ℃
2Supercritical extraction; (3) volatile substances after will extracting and known medicinal or edible carrier are mixed and made into the above any dosage form of pharmaceutics.
A kind of health medicine preparation of compositions technology of improving sleep comprises the steps: that (1) press the weight percentage preparation health composition of raw material Flos Caryophylli 15-35%, Semen Myristicae 15-35%, Cortex Cinnamomi 10-18%, Resina Ferulae 25-35%, Rhizoma Kaempferiae 15-25%, black pepper 10-25% and pulverize; (2) raw material of pulverizing is carried out CO under pressure 25-35Mpa, temperature 30-50 ℃
2Supercritical extraction; (3) volatile substances after will extracting and known medicinal or edible carrier are mixed and made into the above any dosage form of pharmaceutics.
The present invention has following advantage compared to existing technology:
1, the raw material in the compatibility of the present invention is the raw material with volatile oil, and its volatile oil and fat-soluble part are for to improving the live part of sleep quality.
2, the Flos Caryophylli in the raw material of the present invention contains volatile oil such as eugenol, chavicol, syringone, vanillin, kaempferide, oleanolic acid, rhamonic acid; The Main Ingredients and Appearance eugenol of its volatile oil part has tangible calmness and anticonvulsant action.
3, the myristic volatile oil in the raw material of the present invention partly is myristicin, eugenol, Semen Myristicae glyceride, and wherein myristicin causes unreal effect.Methyl isobutyl phenol can suppress nervus centralis in the volatile oil; Behind the rabbit ear iv50mg/Kg, the sleep righting reflex loss; Volatile oil, fatty oil, starch, protein, Saponin.
4, black pepper has calmness and anticonvulsant action in the raw material of the present invention.
5, Rhizoma Kaempferiae has dual function to the intestinal smooth muscle in the raw material of the present invention, and bacteriostasis is arranged.
6, Resina Ferulae of the present invention has blood coagulation resisting function.
7, compatibility of the present invention is got volatile oil in the crude drug and fat-soluble part as its live part, and its compatibility has the tranquilization and nourishing effect.Full side is suffering, hardship, mild medicine, returns taste warp, the sick sympotoms caused by cold factors that belong to of dragon, and warm nature or hot medicine all can alleviate or eliminate sympotoms caused by cold factors.Flos Caryophylli has warming middle-JIAO to send down the adverse-rising QI, warming the kidney to activate YANG effect.Fructus Piperis obligate sun is bright, can make guiding drug, clinical treatment coronary heart disease.The Semen Myristicae warming middle-JIAO to promote flow of QI, the Tibetan medicine treats various heart diseases with two, and relieving palpitation is controlled cardiopathia.Resina Ferulae tranquilization and nourishing medicine is owing to be worried too, the vim and vigour deficiency of conscience, and lack of preservation of spirit or insufficiency of heart-YIN are disturbed in the asthenic fire, show as palpitation with fear, forgetful, fidgets due to deficiency is insomnia, and generally mostly is deficient syndrome.The present invention is principal agent with the Resina Ferulae, hot temperature cold expelling, promoting flow of QI and blood, tranquilizing by nourishing the heart, promoting the circulation of QI to relieve pain.The product of Flos Caryophylli, Nutmeg fragrance, activating QI and resolving turbid pathogen, the refreshment of having one's ideas straightened out; The stasis of blood of promoting the circulation of blood branch stagnates, the QI and blood of reinforcing the heart and calming the nerves, and painstaking effort must be mended, and the motive is benefited, and then the mind is from peace.Compatibility of the present invention has to mend row, has both supported its mind, and its gods of waking up are arranged, and mends row and takes into account.Rhizoma Kaempferiae, black pepper, Cortex Cinnamomi are adjuvant drug altogether, and warming spleen and stomach for dispelling cold is to help the disease of principal agent treatment trusted subordinate cold type of pain; Comprehensive promoting flow of QI and blood, warming spleen and stomach for dispelling cold, the effect of playing tranquilizing by nourishing the heart altogether.
Concrete embodiment
The present invention also will be described in further detail in conjunction with the embodiments:
Embodiment one:
A kind of health medicine compositions of improving sleep is made the above any dosage form of pharmaceutics by following raw materials in percentage by weight by known formulation method: Flos Caryophylli 25%, Semen Myristicae 15%, Cortex Cinnamomi 15%, Resina Ferulae 25%, Rhizoma Kaempferiae 10%, black pepper 10%.
A kind of health medicine preparation of compositions technology of improving sleep, comprise the steps: (1) with the raw material of above-mentioned health composition by its weight percentage preparation and pulverize; (2) raw material of pulverizing is packed into charging basket, the extraction kettle of the supercritical extraction equipment of then charging basket being packed into seals, and keeps extraction kettle pressure under 40 ℃ of 30Mpa, temperature, and CO is carried out in circulation continuously
2Supercritical extraction 3 hours separates through detached dowel, obtains the rectification part from extraction-container I, II respectively, collects extract; (3) volatile substances and the known capsule carrier after will extracting is mixed and made into capsule.
Embodiment two:
A kind of health medicine compositions of improving sleep is made the above any dosage form of pharmaceutics by following raw materials in percentage by weight by known formulation method: Flos Caryophylli 35%, Semen Myristicae 10%, Cortex Cinnamomi 10%, Resina Ferulae 20%, Rhizoma Kaempferiae 15%, black pepper 10%.
Its preparation technology and example are together.
Embodiment three:
A kind of health medicine compositions of improving sleep is made the above any dosage form of pharmaceutics by following raw materials in percentage by weight by known formulation method: Flos Caryophylli 10%, Semen Myristicae 25%, Cortex Cinnamomi 10%, Resina Ferulae 35%, Rhizoma Kaempferiae 10%, black pepper 10%.
Its preparation technology and example are together.
Embodiment four:
A kind of health medicine compositions of improving sleep is made the above any dosage form of pharmaceutics by following raw materials in percentage by weight by known formulation method: Flos Caryophylli 15%, Semen Myristicae 20%, Cortex Cinnamomi 10%, Resina Ferulae 30%, Rhizoma Kaempferiae 10%, black pepper 15%.
Its preparation technology and example are together.
Embodiment five:
A kind of health medicine compositions of improving sleep is made the above any dosage form of pharmaceutics by following raw materials in percentage by weight by known formulation method: Flos Caryophylli 10%, Semen Myristicae 35%, Cortex Cinnamomi 15%, Resina Ferulae 20%, Rhizoma Kaempferiae 10%, black pepper 10%.
Its preparation technology and example are together.
Embodiment six:
A kind of health medicine compositions of improving sleep is made the above any dosage form of pharmaceutics by following raw materials in percentage by weight by known formulation method: Flos Caryophylli 10%, Semen Myristicae 10%, Cortex Cinnamomi 10%, Resina Ferulae 20%, Rhizoma Kaempferiae 25%, black pepper 25%.
Its preparation technology and example are together.
Claims (2)
1, a kind of health medicine preparation of compositions technology of improving sleep comprises the steps: that (1) press the weight percentage preparation health composition of raw material Flos Caryophylli 10-40%, Semen Myristicae 10-40%, Cortex Cinnamomi 10-20%, Resina Ferulae 20-40%, Rhizoma Kaempferiae 10-30%, black pepper 10-30% and pulverize; (2) raw material of pulverizing is carried out CO under pressure 25-35Mpa, temperature 30-50 ℃
2Supercritical extraction; (3) volatile substances after will extracting and known medicinal or edible carrier are mixed and made into the above any dosage form of pharmaceutics.
2, a kind of health medicine preparation of compositions technology of improving sleep comprises the steps: that (1) press the weight percentage preparation health composition of raw material Flos Caryophylli 15-35%, Semen Myristicae 15-35%, Cortex Cinnamomi 10-18%, Resina Ferulae 25-35%, Rhizoma Kaempferiae 15-25%, black pepper 10-25% and pulverize; (2) raw material of pulverizing is carried out CO under pressure 25-35Mpa, temperature 30-50 ℃
2Supercritical extraction; (3) volatile substances after will extracting and known medicinal or edible carrier are mixed and made into the above any dosage form of pharmaceutics.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02139459 CN1293914C (en) | 2002-09-19 | 2002-09-19 | Health care medicinal composition for improving sleeping and preparation preocess thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02139459 CN1293914C (en) | 2002-09-19 | 2002-09-19 | Health care medicinal composition for improving sleeping and preparation preocess thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1483430A CN1483430A (en) | 2004-03-24 |
| CN1293914C true CN1293914C (en) | 2007-01-10 |
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ID=34147454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02139459 Expired - Fee Related CN1293914C (en) | 2002-09-19 | 2002-09-19 | Health care medicinal composition for improving sleeping and preparation preocess thereof |
Country Status (1)
| Country | Link |
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| CN (1) | CN1293914C (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101244231B (en) * | 2008-02-28 | 2010-11-24 | 陆瑾 | Chinese medicine fragrant composition, its preparation and application |
| CN107007666A (en) * | 2017-04-25 | 2017-08-04 | 西藏文殊生物科技有限公司 | Composition for the treatment of and improvement insomnia and its production and use |
| CN107184662A (en) * | 2017-08-01 | 2017-09-22 | 青海民族大学 | A kind of composition for improving sleep and preparation method thereof |
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2002
- 2002-09-19 CN CN 02139459 patent/CN1293914C/en not_active Expired - Fee Related
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| Publication number | Publication date |
|---|---|
| CN1483430A (en) | 2004-03-24 |
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