CN1282337A - 具有整联蛋白抑制剂特性的环肽衍生物 - Google Patents
具有整联蛋白抑制剂特性的环肽衍生物 Download PDFInfo
- Publication number
- CN1282337A CN1282337A CN98812195A CN98812195A CN1282337A CN 1282337 A CN1282337 A CN 1282337A CN 98812195 A CN98812195 A CN 98812195A CN 98812195 A CN98812195 A CN 98812195A CN 1282337 A CN1282337 A CN 1282337A
- Authority
- CN
- China
- Prior art keywords
- gly
- asp
- phe
- arg
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/10—Process efficiency
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19755800A DE19755800A1 (de) | 1997-12-16 | 1997-12-16 | Cyclopeptidderivate |
DE19755800.3 | 1997-12-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN1282337A true CN1282337A (zh) | 2001-01-31 |
Family
ID=7852041
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN98812195A Pending CN1282337A (zh) | 1997-12-16 | 1998-12-09 | 具有整联蛋白抑制剂特性的环肽衍生物 |
Country Status (14)
Country | Link |
---|---|
US (2) | US6610826B1 (de) |
EP (1) | EP1037906B1 (de) |
JP (1) | JP3844655B2 (de) |
KR (1) | KR20010033103A (de) |
CN (1) | CN1282337A (de) |
AT (1) | ATE289320T1 (de) |
AU (1) | AU735386B2 (de) |
CA (1) | CA2315532C (de) |
DE (2) | DE19755800A1 (de) |
ES (1) | ES2237857T3 (de) |
HU (1) | HUP0004511A3 (de) |
PL (1) | PL340502A1 (de) |
WO (1) | WO1999031126A1 (de) |
ZA (1) | ZA9811462B (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7815900B1 (en) | 2000-07-11 | 2010-10-19 | L'ORéAL S.A. | Use of C3-C5 monosaccharides to protect keratinous fibers |
DE10040105A1 (de) * | 2000-08-17 | 2002-02-28 | Merck Patent Gmbh | Peptid- und Peptidmimetika-Derivate mit Integrin-Inhibitor-Eigenschaften |
DE10040103A1 (de) * | 2000-08-17 | 2002-02-28 | Merck Patent Gmbh | Peptid- und Peptidmimetika-Derivate mit Integrin-Inhibitor-Eigenschaften II |
AU2001221607A1 (en) | 2000-11-20 | 2002-05-27 | Ecole Polytechnique Federale De Lausanne (Epfl) | Endosseous implant |
DE10325049A1 (de) * | 2003-06-02 | 2004-12-23 | Merck Patent Gmbh | Peptid- und Peptidmimetika-Derivate mit Integrin-Inhibitor-Eigenschaften III |
US7528106B2 (en) | 2004-06-04 | 2009-05-05 | The Scripps Research Institute | Compositions and methods for treatment of neovascular diseases |
AU2006262329B2 (en) * | 2005-06-22 | 2011-04-07 | Asterias Biotherapeutics, Inc. | Differentiation of primate pluripotent stem cells to cardiomyocyte-lineage cells |
KR101635750B1 (ko) * | 2008-01-30 | 2016-07-04 | 아스테리아스 바이오세라퓨틱스, 인크. | 줄기 세포 유래 올리고덴드로사이트 전구 세포를 배양하기 위한 합성 표면 |
SG188098A1 (en) | 2008-01-30 | 2013-03-28 | Geron Corp | Synthetic surfaces for culturing stem cell derived cardiomyocytes |
WO2009124754A1 (en) * | 2008-04-08 | 2009-10-15 | Merck Patent Gmbh | Compositions containing cyclic peptides and methods of use |
US20110183418A1 (en) * | 2009-07-29 | 2011-07-28 | Arthur Winston Martin | Peptide-Polymer Cell Culture Articles and Methods of Making |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19538741A1 (de) * | 1995-10-18 | 1997-04-24 | Merck Patent Gmbh | Cyclopeptidderivate |
EP0844252A3 (de) * | 1996-11-15 | 1998-07-08 | Remacle, José | Zyklische Peptide mit einer zur anschliessenden chemischen Kupplung entworfenen Zweiggruppe und Verfahren zu deren Herstellung |
DE19725368A1 (de) * | 1997-06-16 | 1998-12-17 | Merck Patent Gmbh | Cyclische Adhäsionsinhibitoren und deren Verwendung für bildgebende Verfahren |
-
1997
- 1997-12-16 DE DE19755800A patent/DE19755800A1/de not_active Withdrawn
-
1998
- 1998-12-09 CA CA002315532A patent/CA2315532C/en not_active Expired - Fee Related
- 1998-12-09 AU AU22689/99A patent/AU735386B2/en not_active Ceased
- 1998-12-09 US US09/581,575 patent/US6610826B1/en not_active Expired - Lifetime
- 1998-12-09 HU HU0004511A patent/HUP0004511A3/hu unknown
- 1998-12-09 WO PCT/EP1998/008003 patent/WO1999031126A1/de not_active Application Discontinuation
- 1998-12-09 KR KR1020007006466A patent/KR20010033103A/ko not_active Application Discontinuation
- 1998-12-09 PL PL98340502A patent/PL340502A1/xx unknown
- 1998-12-09 ES ES98966267T patent/ES2237857T3/es not_active Expired - Lifetime
- 1998-12-09 CN CN98812195A patent/CN1282337A/zh active Pending
- 1998-12-09 DE DE59812581T patent/DE59812581D1/de not_active Expired - Lifetime
- 1998-12-09 JP JP2000539049A patent/JP3844655B2/ja not_active Expired - Fee Related
- 1998-12-09 AT AT98966267T patent/ATE289320T1/de active
- 1998-12-09 EP EP98966267A patent/EP1037906B1/de not_active Expired - Lifetime
- 1998-12-14 ZA ZA9811462A patent/ZA9811462B/xx unknown
-
2002
- 2002-06-28 US US10/183,410 patent/US6995238B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1037906B1 (de) | 2005-02-16 |
JP2002508392A (ja) | 2002-03-19 |
DE19755800A1 (de) | 1999-06-17 |
ATE289320T1 (de) | 2005-03-15 |
US20020198142A1 (en) | 2002-12-26 |
ES2237857T3 (es) | 2005-08-01 |
PL340502A1 (en) | 2001-02-12 |
CA2315532C (en) | 2008-02-12 |
JP3844655B2 (ja) | 2006-11-15 |
US6610826B1 (en) | 2003-08-26 |
KR20010033103A (ko) | 2001-04-25 |
US6995238B2 (en) | 2006-02-07 |
CA2315532A1 (en) | 1999-06-24 |
DE59812581D1 (de) | 2005-03-24 |
HUP0004511A3 (en) | 2001-12-28 |
ZA9811462B (en) | 1999-06-15 |
HUP0004511A2 (hu) | 2001-06-28 |
EP1037906A1 (de) | 2000-09-27 |
WO1999031126A1 (de) | 1999-06-24 |
AU2268999A (en) | 1999-07-05 |
AU735386B2 (en) | 2001-07-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN1203090C (zh) | 环化粘合抑制剂 | |
CN1250566C (zh) | 化学修饰的多肽 | |
CN86101850A (zh) | N,n′-二烷基胍基二肽的制造方法与用途 | |
CN1147260A (zh) | 神经激肽(快速激肽)拮抗剂 | |
CN1198841C (zh) | 制备环状血管活性肽的方法 | |
CN1041950A (zh) | 新型肽酶抑制剂 | |
CN1082027A (zh) | 异羟肟酸衍生物 | |
CN1099760A (zh) | 环状粘合抑制剂 | |
CN1085205C (zh) | 双环芳香氨基酸 | |
CN1050198A (zh) | 新的肽酶和异构酶抑制剂 | |
CN1114961A (zh) | 细胞粘连肽抑制剂 | |
CN1042918A (zh) | 具有缓激肽拮抗剂作用的肽类 | |
CN1209437A (zh) | 获得具有正确键合的胱氨酸键的胰岛素前体的改进的方法 | |
CN1098409A (zh) | α-哌嗪酮及其应用 | |
CN1282337A (zh) | 具有整联蛋白抑制剂特性的环肽衍生物 | |
CN1829738A (zh) | 新型胰岛素衍生物 | |
CN1278790A (zh) | 化合物 | |
CN1150189C (zh) | 用作整联蛋白抑制剂的苯并吡喃酮和苯并二氢吡喃酮衍生物 | |
CN1204889C (zh) | 粘附受体拮抗剂 | |
CN1099040A (zh) | 线性粘合抑制剂 | |
CN1107857A (zh) | 环状氨基酸衍生物 | |
CN1518558A (zh) | 肽和/或蛋白质及其用于制备治疗性和/或预防性药物组合物的用途 | |
CN1181092C (zh) | 可用于治疗前列腺癌的缀合物 | |
CN1777439A (zh) | 生长抑素的载体 | |
CN1054857C (zh) | 具有胃肠道运动刺激活性的胃动素样多肽 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
WD01 | Invention patent application deemed withdrawn after publication |