HUP0004511A3 - Cyclopeptide derivatives with integrin inhibitor properties, process for preparation thereof and their use - Google Patents

Cyclopeptide derivatives with integrin inhibitor properties, process for preparation thereof and their use

Info

Publication number
HUP0004511A3
HUP0004511A3 HU0004511A HUP0004511A HUP0004511A3 HU P0004511 A3 HUP0004511 A3 HU P0004511A3 HU 0004511 A HU0004511 A HU 0004511A HU P0004511 A HUP0004511 A HU P0004511A HU P0004511 A3 HUP0004511 A3 HU P0004511A3
Authority
HU
Hungary
Prior art keywords
preparation
integrin inhibitor
inhibitor properties
cyclopeptide derivatives
cyclopeptide
Prior art date
Application number
HU0004511A
Other languages
Hungarian (hu)
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of HUP0004511A2 publication Critical patent/HUP0004511A2/en
Publication of HUP0004511A3 publication Critical patent/HUP0004511A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/10—Process efficiency

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HU0004511A 1997-12-16 1998-12-09 Cyclopeptide derivatives with integrin inhibitor properties, process for preparation thereof and their use HUP0004511A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19755800A DE19755800A1 (en) 1997-12-16 1997-12-16 Cyclopeptide derivatives
PCT/EP1998/008003 WO1999031126A1 (en) 1997-12-16 1998-12-09 Cyclopeptide derivatives with integrin inhibitor properties

Publications (2)

Publication Number Publication Date
HUP0004511A2 HUP0004511A2 (en) 2001-06-28
HUP0004511A3 true HUP0004511A3 (en) 2001-12-28

Family

ID=7852041

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0004511A HUP0004511A3 (en) 1997-12-16 1998-12-09 Cyclopeptide derivatives with integrin inhibitor properties, process for preparation thereof and their use

Country Status (14)

Country Link
US (2) US6610826B1 (en)
EP (1) EP1037906B1 (en)
JP (1) JP3844655B2 (en)
KR (1) KR20010033103A (en)
CN (1) CN1282337A (en)
AT (1) ATE289320T1 (en)
AU (1) AU735386B2 (en)
CA (1) CA2315532C (en)
DE (2) DE19755800A1 (en)
ES (1) ES2237857T3 (en)
HU (1) HUP0004511A3 (en)
PL (1) PL340502A1 (en)
WO (1) WO1999031126A1 (en)
ZA (1) ZA9811462B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7815900B1 (en) 2000-07-11 2010-10-19 L'ORéAL S.A. Use of C3-C5 monosaccharides to protect keratinous fibers
DE10040105A1 (en) * 2000-08-17 2002-02-28 Merck Patent Gmbh Peptide and peptide mimetic derivatives with integrin inhibitor properties
DE10040103A1 (en) * 2000-08-17 2002-02-28 Merck Patent Gmbh Peptide and peptide mimetic derivatives with integrin inhibitor properties II
AU2001221607A1 (en) 2000-11-20 2002-05-27 Ecole Polytechnique Federale De Lausanne (Epfl) Endosseous implant
DE10325049A1 (en) * 2003-06-02 2004-12-23 Merck Patent Gmbh New peptide derivatives containing cell-adhesion molecule and phosphonate-containing anchor component, useful for treating disorders associated with implants, are inhibitors of integrins
KR101224368B1 (en) 2004-06-04 2013-01-22 더 스크립스 리서치 인스티튜트 Compositions and methods for treatment of neovascular diseases
US9062289B2 (en) * 2005-06-22 2015-06-23 Asterias Biotherapeutics, Inc. Differentiation of primate pluripotent stem cells to cardiomyocyte-lineage cells
CA2712891A1 (en) 2008-01-30 2009-08-06 Corning Incorporated Synthetic surfaces for culturing stem cell derived cardiomyocytes
SG188096A1 (en) * 2008-01-30 2013-03-28 Geron Corp Synthetic surfaces for culturing stem cell derived oligodendrocyte progenitor cells
EP2259768B1 (en) 2008-04-08 2019-05-22 Merck Patent GmbH Compositions containing cyclic peptides and methods of use
US20110183418A1 (en) * 2009-07-29 2011-07-28 Arthur Winston Martin Peptide-Polymer Cell Culture Articles and Methods of Making

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19538741A1 (en) * 1995-10-18 1997-04-24 Merck Patent Gmbh Cyclopeptide derivatives
US5939383A (en) * 1996-11-15 1999-08-17 Remacle; Jose Cyclic peptides bearing a tail designed for subsequent chemical coupling and process for preparing same
DE19725368A1 (en) 1997-06-16 1998-12-17 Merck Patent Gmbh New cyclic peptides inhibit ligand binding to integrins

Also Published As

Publication number Publication date
EP1037906B1 (en) 2005-02-16
JP3844655B2 (en) 2006-11-15
WO1999031126A1 (en) 1999-06-24
CA2315532A1 (en) 1999-06-24
US6610826B1 (en) 2003-08-26
KR20010033103A (en) 2001-04-25
CA2315532C (en) 2008-02-12
JP2002508392A (en) 2002-03-19
US6995238B2 (en) 2006-02-07
DE19755800A1 (en) 1999-06-17
DE59812581D1 (en) 2005-03-24
ES2237857T3 (en) 2005-08-01
HUP0004511A2 (en) 2001-06-28
CN1282337A (en) 2001-01-31
US20020198142A1 (en) 2002-12-26
AU735386B2 (en) 2001-07-05
PL340502A1 (en) 2001-02-12
ZA9811462B (en) 1999-06-15
AU2268999A (en) 1999-07-05
ATE289320T1 (en) 2005-03-15
EP1037906A1 (en) 2000-09-27

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