CN1281211C - 噁唑烷酮类物质在制备治疗哺乳动物眼部感染的药物中的用途 - Google Patents

噁唑烷酮类物质在制备治疗哺乳动物眼部感染的药物中的用途 Download PDF

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Publication number
CN1281211C
CN1281211C CNB028154673A CN02815467A CN1281211C CN 1281211 C CN1281211 C CN 1281211C CN B028154673 A CNB028154673 A CN B028154673A CN 02815467 A CN02815467 A CN 02815467A CN 1281211 C CN1281211 C CN 1281211C
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CN
China
Prior art keywords
formula
chemical compound
mixture
purposes
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB028154673A
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English (en)
Chinese (zh)
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CN1545428A (zh
Inventor
J·G·斯拉特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Pharmacia and Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Pharmacia and Upjohn Co filed Critical Pharmacia and Upjohn Co
Publication of CN1545428A publication Critical patent/CN1545428A/zh
Application granted granted Critical
Publication of CN1281211C publication Critical patent/CN1281211C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541Non-condensed thiazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CNB028154673A 2001-09-14 2002-09-11 噁唑烷酮类物质在制备治疗哺乳动物眼部感染的药物中的用途 Expired - Fee Related CN1281211C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US32215301P 2001-09-14 2001-09-14
US32211501P 2001-09-14 2001-09-14
US60/322,153 2001-09-14
US60/322,115 2001-09-14

Publications (2)

Publication Number Publication Date
CN1545428A CN1545428A (zh) 2004-11-10
CN1281211C true CN1281211C (zh) 2006-10-25

Family

ID=26983274

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB028154673A Expired - Fee Related CN1281211C (zh) 2001-09-14 2002-09-11 噁唑烷酮类物质在制备治疗哺乳动物眼部感染的药物中的用途

Country Status (12)

Country Link
US (2) US20030069235A1 (https=)
EP (1) EP1425068A1 (https=)
JP (1) JP2005507884A (https=)
KR (1) KR20040035769A (https=)
CN (1) CN1281211C (https=)
BR (1) BR0212466A (https=)
CA (1) CA2460360A1 (https=)
IL (1) IL160490A0 (https=)
MX (1) MXPA04002071A (https=)
NZ (1) NZ531353A (https=)
PL (1) PL370033A1 (https=)
WO (1) WO2003024528A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108283622A (zh) * 2018-04-03 2018-07-17 广州君博医药科技有限公司 一种缓释型利奈唑胺眼用药物及其制备方法
WO2021184339A1 (en) 2020-03-20 2021-09-23 Merck Sharp & Dohme Corp. Oxazolidinone compound and methods of use thereof as an antibacterial agent

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
CN1305374A (zh) * 1998-07-14 2001-07-25 法玛西雅厄普约翰美国公司 治疗眼部感染的噁唑烷酮
ATE337002T1 (de) * 1999-09-13 2006-09-15 Insite Vision Inc Topische behandlung zur vorbeugung von augeninfektionen
US6696426B2 (en) * 2000-08-22 2004-02-24 Pharmacia Corporation Preservative free ophthalmic oxazolidinone antibiotic drug delivery systems
PE20020578A1 (es) * 2000-10-10 2002-08-14 Upjohn Co Una composicion de antibiotico topico para el tratamiento de infecciones oculares

Also Published As

Publication number Publication date
WO2003024528A1 (en) 2003-03-27
US20030069235A1 (en) 2003-04-10
CA2460360A1 (en) 2003-03-27
IL160490A0 (en) 2004-07-25
MXPA04002071A (es) 2005-02-17
KR20040035769A (ko) 2004-04-29
NZ531353A (en) 2006-09-29
CN1545428A (zh) 2004-11-10
US20050234052A1 (en) 2005-10-20
HK1068564A1 (en) 2005-04-29
EP1425068A1 (en) 2004-06-09
PL370033A1 (en) 2005-05-16
BR0212466A (pt) 2004-10-19
JP2005507884A (ja) 2005-03-24

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