CN1279965C - Traditional Chinese medicine preparation for treating cranial vascular diseases, its preparation method and application - Google Patents
Traditional Chinese medicine preparation for treating cranial vascular diseases, its preparation method and application Download PDFInfo
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- CN1279965C CN1279965C CNB2004100062377A CN200410006237A CN1279965C CN 1279965 C CN1279965 C CN 1279965C CN B2004100062377 A CNB2004100062377 A CN B2004100062377A CN 200410006237 A CN200410006237 A CN 200410006237A CN 1279965 C CN1279965 C CN 1279965C
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Abstract
The present invention relates to a traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases, and a preparing method and the application thereof. The traditional Chinese medicine preparation of the present invention contains tea, tuckahoe, cornus officinalis, cassia seed, radix trichosanthis, scrophularia, mulberry leaf, gingko, double blossom, stir-frying hawthorn, endothelium corneae gigeriae galli, baical skullcap root, notoginseng and stir-frying Fructus Amomi Villosi. The concrete formula and the preparing method are disclosed in the instruction. The present invention has the advantages that the present invention carries on the essence of a secret prescription handed down in the family from generation to generation, and the focus of infection on human bodies is comprehensively regulated and treated at multitarget positions and multitarget points. The present invention also has the advantages of wide range of application, few toxic or side effects, good taste, convenient taking, safety, high efficiency and medium cost; all the ingredients are all-natural plants. The present invention is preferably adopted for health care by patients suffering from hypertension, hyperglycemia, hyperlipoidemia and complication thereof. The product of the present invention is mainly used for treating hypertension, hyperglycemia, hyperlipoidemia and complication thereof.
Description
Technical field
The present invention relates to Chinese medicine preparation, specifically, relate to a kind of Chinese medicine preparation, preparation method and application thereof for the treatment of cardiovascular and cerebrovascular disease.
Background technology
Raising along with people's living standard, smart grain is carefully cooked on diet, and keen competition causes crunch for people's body and mind, people are hypokinesia in the city, environmental pollution in addition, cause diabetes, hypertension, interior syndrome state sickness rate such as hyperlipidemia are soaring year by year, clinical manifestation is that diet is many, it is many to drink water, frequent micturition, lose weight, with dizziness, whole body symptom such as unable, at present insulin injections and Western medicine of adopting are taken Western medicine between often more, drug resistance can appear in people's health, and to the patient liver, internal organs negative effects such as kidney particularly suffer from hyperglycemia simultaneously, hypertension, the patient of hyperlipidemia, usually the cooperation of multiple medicine is taken, can reach therapeutic effect, so the normal at present Therapeutic Method that adopts the multiple medicines cooperation to take makes the extensive patients health, psychology, bearing very big pressure economically, therefore throughout the year, be badly in need of seeking a kind of fast and convenient, eutherapeutic Chinese medicine preparation is so that treat this disease.
Summary of the invention
The objective of the invention is to overcome above-mentioned problems of the prior art, and a kind of safe and effective, perfect in shape and function, moderate a kind of Chinese medicine preparation, preparation method and the application thereof for the treatment of cardiovascular and cerebrovascular disease of cost are provided.
The present invention is that fork-like farm tool used in ancient China is realized by the following technical programs: a kind of Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease is the Chinese medicine preparation with the feedstock production one-tenth of following weight ratio:
Folium Camelliae sinensis: 30-35 part Poria: 10-15 part Fructus Corni: 6-11 part
Semen Cassiae: 6-11 part Radix Trichosanthis: 5-15 part Radix Scrophulariae: 5-10 part
Folium Mori: 3-8 part Semen Ginkgo: 3-8 part Flos Lonicerae: 3-8 part
Fructus Crataegi (parched): 3-8 part Endothelium Corneum Gigeriae Galli: 3-8 part Radix Scutellariae: 3-8 part
Radix Notoginseng: 1-5 part Fructus Amomi: 1-5 part
Chinese medicine preparation of the present invention comprises capsule and two kinds of forms of teabag, wherein:
Capsular preparation method is: by above-mentioned formulation weight, become Folium Camelliae sinensis, Endothelium Corneum Gigeriae Galli, Radix Notoginseng pulverize separately fine powder stand-by.Fructus Corni, Semen Cassiae, Semen Ginkgo, Fructus Amomi lumps together, add 8-10 times of distilled water distillation, extract volatile oil, in medicine, there is not volatile oil, its medicinal residues and Poria, Radix Trichosanthis, Radix Scrophulariae, Folium Mori, Flos Lonicerae, Fructus Crataegi (parched), Radix Scutellariae mixes, add 8-10 times of distilled water and decoct twice, each 0.5-1 hour, decoct filtrate merging with twice, be concentrated into relative density 1.15-1.20,60-65 ℃, add 2-4 times of ethanol by volume, stir, reclaim ethanol, and be concentrated into relative density 1.25-1.30,60-65 ℃ thick paste, add the Radix Notoginseng fine powder, mixing after the 60-80 ℃ of drying, is ground into fine powder, above-mentioned volatile oil is sprayed at Folium Camelliae sinensis, in the Endothelium Corneum Gigeriae Galli fine powder, air-dry back with above-mentioned make contain fine powder mixing such as Radix Notoginseng, incapsulate, promptly get product of the present invention;
The preparation method of teabag: clean raw material earlier, will Poria, Fructus Corni, Semen Cassiae, Radix Trichosanthis, Radix Scrophulariae, Folium Mori, Semen Ginkgo, Flos Lonicerae, Fructus Crataegi (parched), Radix Scutellariae put into the water rinsing after mixing, by weight, with the water ratio be 1: 1.5, after the rinsing 0.6 hour, take out oven dry, 40-50 ℃, after 3-3.5 hour, mix with Folium Camelliae sinensis, Endothelium Corneum Gigeriae Galli, Radix Notoginseng, Fructus Amomi again, be crushed to the 40-50 order, pack, sterilization promptly get product of the present invention.
Composition of raw materials of the present invention is a marrow of inheriting hereditary recipe, and disease is carried out the synthesis treatment of the many target spots of multi-angle, utilizes that modern crafts are refining to form.The present invention is based on strengthening the body resistance, hold concurrently and take stopgap measures with eliminating evil, with YIN nourishing and the production of body fluid promoting, moistening for dryness and clearing away heat, warmly invigorating spleen yang, blood circulation promoting and blood stasis dispelling is the rule of treatment, the diet that diabetes, hypertension, hyperlipidemia are caused is many, drinking a lot of water, frequent micturition, lose weight, unable, dizzy, the red tongue in the whole body, full and rapid pulse or deficient pulse unable for the hyperactivity of fire caused by deficiency of YIN of cardinal symptom, reach deficiency of both QI and YIN quench one's thirst (diabetes) and hypertension that excessive rising of liver-YANG causes has definite curative effect.The index of medication mainly is blood sugar lowering (blood glucose, a glucose in urine) hypotensive effect, blood circulation promoting and blood stasis dispelling effect for reducing blood fat, detoxicating, relieving inflammation effect, long term toxicity effect test etc.
The raw material that the present invention is used, the wherein chlorophyll in the Folium Camelliae sinensis, vitamin, trace element, the several amino acids composition has the effect that strengthens body immunity, anti-inflammation, and Folium Camelliae sinensis is green tea, scented tea, bird dragon tea, black tea; The Poria main component is β-pachyman, pachymic acid etc., has the body immunity of enhancing and protects the liver the kidney effect of protecting; Contain compositions such as mountain cornel glycoside, river deer tooth Lay glycoside, malic acid, tartaric acid in the Fructus Corni, the cardiac function that has clear improvement, protect the liver the effect of protecting the kidney blood sugar lowering; Contain pollen protein and several amino acids in the Radix Trichosanthis, have tangible blood sugar reducing function; Fructus Crataegi (parched) contains flavonoid and organic acid composition, has tangible blood pressure lowering heart tonifying effect for reducing fat; Chlorogenic acid in the Flos Lonicerae, isochlorogenic acid have broad-spectrum antibacterial action; Baicalin in the Radix Scutellariae and baicalin composition have the effect of antiinflammatory, blood pressure lowering, hepatoprotective; Contain compositions such as panoxadiol's type Saponin and flavonoid glycoside in the Radix Notoginseng, obvious anticoagulant, blood sugar lowering, blood fat reducing, anti-arrhythmia, anti-inflammatory and analgesic effect are arranged, in addition, Semen Cassiae, Radix Scrophulariae, Folium Mori, Semen Ginkgo, Flos Lonicerae, Endothelium Corneum Gigeriae Galli, Fructus Amomi all have blood sugar lowering, blood pressure lowering, effect for reducing blood fat.
The present invention compared with prior art has following advantage: product utilization crowd of the present invention is wide, hypertension, hyperlipidemia, hyperglycemia all there is tangible curative effect, effective percentage is 93%, and taken into account the control of many complication that cause because of three-hypers disease, provide good mouthfeel, taking convenience, the custom of taking that meets modern people's healthcare products, its composition is pure natural plant, and toxic and side effects is extremely low, has catered to people again medicine is pursued naturally safely and effectively.
The specific embodiment
Enumerate two embodiment below, the present invention is further specified, but the present invention is not only limited to these embodiment.
Embodiment 1
300 gram Folium Camelliae sinensis (green tea, scented tea, oolong tea, black tea), 30 gram Endothelium Corneum Gigeriae Galli, 10 gram Radix Notoginseng pulverize separately are become smalls.The 60 Keshan Fructus Evodiaes, 60 gram Semen Cassiae, 30 gram Semen Ginkgoes, 10 gram Fructus Amomis are lumped together, add 1600 gram distilled water steaming and decoctings, extract volatile oil, do not have volatile oil in medicine, the volatile oil of extraction is collected in the vessel.Medicinal residues and 100 gram Poria, 50 gram Radix Trichosanthis, 50 gram Radix Scrophulariae, 30 gram Folium Mori, 60 gram Flos Loniceraes, 30 gram Fructus Crataegi (parched), 30 gram Radix Scutellariaes mix, and add 3500 gram distilled water steaming and decoctings twice, and digestion time is 30-40 minute, collecting decoction, filter, this filtrate is concentrated into relative density 1.15-1.20,60-65 ℃, add 3 times of volume of ethanol, make to contain ethanol 70%, fully stir, left standstill 24 hours, get supernatant, reclaim ethanol, and concentrated relative density 1.25-1.30,60-65 ℃ thick paste, add the Radix Notoginseng fine powder, mixing, 60-80 ℃ of drying is ground into fine powder, above-mentioned volatile oil is sprayed in Folium Camelliae sinensis and the Endothelium Corneum Gigeriae Galli fine powder, air-dry, add above-mentioned make contain in the Radix Notoginseng fine powder mixing, incapsulate, promptly get product of the present invention.
Embodiment 2
Prescription by Chinese medicine preparation of the present invention, the Radix Scrophulariae of 10 gram Poria, the 6 Keshan Fructus Evodiaes, 6 gram Semen Cassiae, 5 gram Radix Trichosanthis, 5 grams, 3 gram Folium Mori, 3 gram Semen Ginkgoes, 6 gram Flos Loniceraes, 3 gram Fructus Crataegi (parched), 3 gram Radix Scutellariaes are placed rinsing in the water, with the water ratio be 1: 1.5, after the rinsing 1 hour, take out 40-50 ℃ of oven dry 3 hours, be crushed to the 40-45 order jointly with 30 gram Folium Camelliae sinensis, 3 gram Endothelium Corneum Gigeriae Galli, 1 gram Radix Notoginseng, 1 gram Fructus Amomi again, the back pack stirs, every bag 2 or 3 grams, sterilization promptly gets product of the present invention.
The present invention carries out clinical observation, and its result is as follows:
1, physical data
Use patient's 81 examples of this product treatment hyperglycemia, hypertension, hyperlipidemia and complication thereof, wherein male 60 examples, women 21 examples, the oldest 78 years old, minimum 21 years old, the elder of the course of disease 20 years, the shortest person 1.5 years.
One, diagnostic criteria
(1), tcm diagnosis standard
Main symptom: thirsty, polyphagia, polyuria, dizziness, lose weight
Unable, the being irritable and getting angry easily in the whole body, skin Pruritus, easy infection, red tongue, full and rapid pulse or deficient pulse are unable
(2), Chinese medical discrimination
Pattern of syndrome: hyperactivity of fire caused by deficiency of YIN, deficiency of both QI and YIN, the hepatic and renal YIN deficiency
(3), Western medicine diagnose standard
Fasting glucose 〉=7.0mmol/l or 2 hours after meal blood glucose 〉=11.1mmol/l or blood glucose 〉=11.1mmol/l any time, diagnosable is diabetes
The not obvious person of asymptomatic person or symptom, fasting glucose or after meal blood glucose be higher than normal value, but do not reach diagnostic criteria person, should do the glucose sugar tolerance test
(4), with the pressure value be standards of grading 170/130mmHg 4 minutes
150/120mmHg 5 minutes
130/110mmHg 2 minutes
125/100mmHg 1 minute
120/80mmHg 0 minute
Two, curative effect determinate standard and foundation
A, clinical recovery: clinical symptoms, body card integration reduces 〉=95%, and blood glucose, glucose in urine, pressure value are normal
B, comparatively improvement: clinical symptoms body card integration reduces 70-90%, and blood glucose, glucose in urine, pressure value are clearly better
C, effective: clinical symptoms body card integration reduces 50-70%, and blood glucose, glucose in urine, pressure value comparatively take a turn for the better
D, invalid: clinical symptoms body card integration reduces≤50%, and blood glucose, glucose in urine, pressure value do not have change
Product of the present invention is mainly used in treatment hypertension, hyperglycemia, high fat of blood and complication thereof.
Claims (4)
1, a kind of Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease is characterized in that it is the Chinese medicine preparation that becomes with the feedstock production of following weight ratio:
Folium Camelliae sinensis: 30-35 part Poria: 10-15 part Fructus Corni: 6-11 part
Semen Cassiae: 6-11 part Radix Trichosanthis: 5-15 part Radix Scrophulariae: 5-10 part
Folium Mori: 3-8 part Semen Ginkgo: 3-8 part Flos Lonicerae: 3-8 part
Fructus Crataegi (parched): 3-8 part Endothelium Corneum Gigeriae Galli: 3-8 part Radix Scutellariae: 3-8 part
Radix Notoginseng: 1-5 part Fructus Amomi: 1-5 part.
2, a kind of preparation method of Chinese medicine preparation of treatment cardiovascular and cerebrovascular disease as claimed in claim 1 is characterized in that, preparation method is: by above-mentioned formulation weight, become Folium Camelliae sinensis, Endothelium Corneum Gigeriae Galli, Radix Notoginseng pulverize separately fine powder stand-by; Fructus Corni, Semen Cassiae, Semen Ginkgo, Fructus Amomi lumps together, add 8-10 times of distilled water distillation, extract volatile oil, in medicine, there is not volatile oil, its medicinal residues and Poria, Radix Trichosanthis, Radix Scrophulariae, Folium Mori, Flos Lonicerae, Fructus Crataegi (parched), Radix Scutellariae mixes, add 8-10 times of distilled water and decoct twice, each 0.5-1 hour, decoct filtrate merging with twice, be concentrated into relative density 1.15-1.20,60-65 ℃, add 2-4 times of ethanol by volume, stir, reclaim ethanol, and be concentrated into relative density 1.25-1.30,60-65 ℃ thick paste, add the Radix Notoginseng fine powder, mixing after the 60-80 ℃ of drying, is ground into fine powder, above-mentioned volatile oil is sprayed at Folium Camelliae sinensis, in the Endothelium Corneum Gigeriae Galli fine powder, air-dry back with above-mentioned make contain Radix Notoginseng fine powder mixing, incapsulate, promptly get product of the present invention.
3, a kind of preparation method for the treatment of the Chinese medicine preparation of cardiovascular and cerebrovascular disease as claim 1, it is characterized in that, preparation method: clean raw material earlier, Poria, Fructus Corni, Semen Cassiae, Radix Trichosanthis, Radix Scrophulariae, Folium Mori, Semen Ginkgo, Flos Lonicerae, Fructus Crataegi (parched), Radix Scutellariae are put into the water rinsing after mixing, by weight, with the water ratio be 1: 1.5, after the rinsing 0.6 hour, take out oven dry, 40-50 ℃, after 3-3.5 hour, mix with Folium Camelliae sinensis, Endothelium Corneum Gigeriae Galli, Radix Notoginseng, Fructus Amomi again, be crushed to the 40-50 order, pack, sterilization.
4, a kind of Chinese medicine preparation as claim 1 treatment cardiovascular and cerebrovascular disease is used for the treatment of the application of the medicine of hypertension, hyperglycemia, high fat of blood and complication thereof.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100062377A CN1279965C (en) | 2004-03-17 | 2004-03-17 | Traditional Chinese medicine preparation for treating cranial vascular diseases, its preparation method and application |
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| Application Number | Priority Date | Filing Date | Title |
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| CNB2004100062377A CN1279965C (en) | 2004-03-17 | 2004-03-17 | Traditional Chinese medicine preparation for treating cranial vascular diseases, its preparation method and application |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1669564A CN1669564A (en) | 2005-09-21 |
| CN1279965C true CN1279965C (en) | 2006-10-18 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB2004100062377A Expired - Fee Related CN1279965C (en) | 2004-03-17 | 2004-03-17 | Traditional Chinese medicine preparation for treating cranial vascular diseases, its preparation method and application |
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| CN101147749B (en) * | 2006-02-21 | 2013-01-02 | 北京旷世伟业科技发展有限责任公司 | Divaricate velvetplant medicinal preparation for treating diabetes |
| CN113769025A (en) * | 2021-11-02 | 2021-12-10 | 刘洪兵 | Traditional Chinese medicine preparation capable of reducing high blood pressure, high blood sugar and high blood lipid, and preparation method and use method thereof |
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Granted publication date: 20061018 Termination date: 20140317 |