CN103623341A - Drug for treating hypertension and cardiovascular and cerebrovascular diseases caused by hypertension - Google Patents
Drug for treating hypertension and cardiovascular and cerebrovascular diseases caused by hypertension Download PDFInfo
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- CN103623341A CN103623341A CN201310541754.3A CN201310541754A CN103623341A CN 103623341 A CN103623341 A CN 103623341A CN 201310541754 A CN201310541754 A CN 201310541754A CN 103623341 A CN103623341 A CN 103623341A
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Abstract
The invention discloses a drug for treating hypertension and cardiovascular and cerebrovascular diseases caused by hypertension. The cardiovascular and cerebrovascular diseases caused by hypertension include arteriosclerosis, coronary heart disease, angina, arrhythmia, myocardial infarction, cerebral thrombosis, cerebral infarction, headache, dizziness, insomnia, frequent micturition, qi-blood-failure dysplasia, sequela of apoplexy, and the like. The drug is prepared into powder or granules according to a normal preparation method of the pharmacopeia by taking ginkgo leaves, gynostemma pentaphylla, salviae miltiorrhizae, haw flakes, pseudo-ginseng, root barks of the peony tree, pubescent holly roots, ligusticum wallichii, curcuma aromatic, Chinese angelica, prepared fleece flower roots, herba epimedii, glossy privet fruits, polygonatum kingianum, cortex lycii radicis, roots of kudzu vine, rhizoma alismatis, earthworms, eucommia ulmoides, loranthus parasiticus, semen cassia, apocynum venetum, uncaria, selfheal, chrysanthemum indicum, lotus plumule herba siegesbeckiae and allium macrostemon as raw materials. The drug disclosed by the invention is exact in curative effect and quick to become effective.
Description
Technical field
The medicine that the present invention relates to a kind of Hypertension and cause thus cardiovascular and cerebrovascular disease, the Chinese patent medicine that the Chinese herbal medicine of specifically take is prepared as raw material.
Background technology
Current prior art, Hypertension and the cardiovascular and cerebrovascular disease causing thus also do not have the medicine of putting things right once and for all in the world.Hypertension is the common frdquently encountered disease of serious harm human health, is also noiseless killer, and the bad meeting of control causes complete and other the multiple complications of cardio and vascular function.Hypertension is global epidemic diseases, is one of Major Risk Factors causing coronary heart disease, apoplexy and renal failure, serious harm human health.Estimate national existing patients with hypertension people more than 100,000,000.One of serious consequence of hypertension causes cerebrovascular accident.In the whole nation, the patients with cerebral apoplexy that hypertension causes is 1,500,000 people every year on average.Case fatality rate occupies second place of the world, causes heavy burden to society, family, individual.
Hypertension be take hypertension as its main manifestations.Due to the existing congenital factors of pathogenic factors, also there is acquired disposition, be difficult to the harm of various paathogenic factors to drop to bottom line; Due to the also not solution of problem of " taking medicine all the life ", so the effective control rate of hypertension is most important.
The traditional Chinese medical science is to hypertensive understanding and Therapeutic Principle
That 1. the cause of disease of hypertension is worried is angry, feelings will is not relaxed, lung qi stasis, strongly fragrant fire-transformation of a specified duration, irritability liver-yang are held under the arm on fire and disturbed, bleeding resulting from adverse flow of QI and cause hypertension; 2. manage for a long time, bother excessively, body and the spirit is lost and is supported, and liver-yin secretly consumes.Liver-fire burn cloudy liquid or old deficiency of both the liver and kidney, YIN failing to keep YANG well, empty positive wind-transformation, wind-yang and up-boring and cause hypertension.3. eating and drinking without temperance, has a liking for food delicious food savoury, and pure wine is excessive, and day multiple day, deficiency of the liver lost fortune, accumulatively wet raise phlegm, and obesity, stagnation of phlegm converting into fire, priming liver-wind, holds under the arm and on expectorant, disturbs and cause hypertension
Traditional Chinese medical herbal treatment principle is adjusted the inclined to one side Sheng of liver, kidney, the heart, spleen negative and positive and QI and blood, partially declines, dispels the excess pathogen such as wind, fire, expectorant, silt, to recover the normal function of body, maintains blood pressure at normal level, delays disease progression, controls or reduce the generation of complication.This principle is also the task that will the complete invention that object of the present invention is held.
The long-standing persistent ailment that the refractory of the headache of world today's medical circle digs up the roots.For example essential hypertension belongs to cardiovascular diseases, and it does not have desirable medicine western medicine, and all has side effect in various degree.Both at home and abroad to hypertension disease medicament treatment, run into following thorny problem at present, for example the common drug of blood pressure lowering has 5 classes: 1. diuretic hydrogen gram this medicine of urine plug, by row's sodium draining diuresis of kidney, can reduce peripheral vascular resistance, reaches the effect of blood pressure lowering.And can causing that hypokalemia and blood glucose, blood uric acid, cholesterol increase, side effect hydrochlorothiazide can accelerate cardio cerebrovascular affection; 2. β _ receptor blocking agent, by the retardance of β _ receptor, makes decreased heart rate, and heart blood discharge amount reduces, and vascular smooth muscle is improved the sensitivity of medium in blood, suppresses renin secretion, reaches antihypertensive effect.And side effect has the bradycardia of causing and conduction block, bronchospasm, heart failure, feels sick, suffers from diarrhoea; Blood glucose, triglyceride, cholesterol, reduction high density lipoprotein gallbladder alcohol level can raise; The unexpected drug withdrawal of patients with coronary heart disease can be brought out angina pectoris.3. calcium antagonist, by the movement of retardance flow of calcium ions and intracellular calcium, affects cardiac muscle and smooth muscle contraction, makes smooth muscle loosening, peripheral blood vessel expansion, thus play blood pressure lowering and Antianginal effect.And side effect makes Blushing, pained dizzy, cardiopalmus, gastrointestinal upset.4. Angiotensin-Converting agent makes Angiotensin II generate minimizing by suppressing Angiotensin-Converting, thereby reduces circulation resistance, reaches blood pressure lowering object.And side effect: headache, feel sick, loss of appetite, dry cough, erythra, nucleus reduce.5. a receptor blocking agent passes through epinephrine, and norepinephrine and orthosympathetic retardance make a1a2 receptor all blocked, reduces peripheral vascular resistance, and expansion is small artery around, thereby reaches hypotensive effect.And side effect: headache, dizzy, weak, tachycardia.
Hypertension is one of Etiological causing cardiovascular disease, and above 5 kinds of western medicine of depressurization all have side effect in various degree.Especially some depressor has been accelerated the side effect of cardio cerebrovascular affection, and conventional Western medicine blood pressure lowering has Drug resistance that drug effect is reduced.
Summary of the invention the object of the present invention is to provide a kind of have blood pressure lowering, blood fat reducing, the blood stasis dispelling of blood circulation and channel invigorating thrombolytic, improves high blood coagulation state, dredging microcirculation, and enhancing human body immunity, the therapeutic agent of the hypertension of hypertension complication effect is alleviated in minimizing.
Solution of the present invention is to hypertension and the pathogenetic understanding of complication and Therapeutic Principle based on motherland's medical science, with reference to present pharmacological research achievement, from motherland's medical treasure-house, filter out nourishing kidney-yin, QI invigorating void, Removing Blood Stasis, pure and impurely let out, the natural edible-plant medicine of the body resistance strengthening and constitution consolidating medicated diet homology, by theory of Chinese medical science ancestral side, skimming the cream off milk, group's medicine is melted is a stove, make its function stack comprehensive utilization strengthen biologos, blood pressure, blood fat are reduced, improve microcirculation, reduce, alleviate the effect that development occurs patients with hypertension cardio cerebrovascular affection.
Its technical characterictic of drug technique scheme of the present invention is that by weight " part " be furnished with following raw materials according combination: Folium Ginkgo 8-25 part, Herb Gynostemmae Pentaphylli 5-15 part, Radix Salviae Miltiorrhizae 5-15 part, Fructus Crataegi slice 5-15 part, Radix Notoginseng 5-15 part, Cortex Moutan 5-15 part, Radix Ilicis Pubescentis 5-15 part, Rhizoma Chuanxiong 5-15 part, Radix Curcumae 5-15 part, Radix Angelicae Sinensis 5-15 part, Radix Polygoni Multiflori Preparata 5-15 part, Herba Epimedii 5-15 part, Fructus Ligustri Lucidi 5-15 part, Rhizoma Polygonati 5-15 part, Cortex Lycii 5-15 part, Radix Puerariae 5-15 part, Cortex Eucommiae 5-15 part, Herba Taxilli 5-15 part, Semen Cassiae 5-15 part, Herba Apocyni veneti 5-25 part, Rhizoma Alismatis 5-25 part, Pheretima 5-25 part, Ramulus Uncariae Cum Uncis 5-25 part, Spica Prunellae 5-25 part, Flos Chrysanthemi Indici 5-15 part, Plumula Nelumbinis 5-15 part, Herba Siegesbeckiae 5-15 part, Bulbus Allii Macrostemonis 5-15 part.
Beneficial effect function with cure mainly: suppressing the hyperactive liver to relieve the wind syndrome relieving convulsion, activating YANG and eliminating stagnation, the diuresis of circulation of qi promoting intestinal stasis relieving, hypertension and hyperlipemia, vessel softening, removing blood stasis, blood circulation and channel invigorating.
Be used for the treatment of hypertension and high fat of blood and the arteriosclerosis causing thus, coronary heart diseases and angina pectoris, arrhythmia, myocardial infarction, cerebral thrombosis, cerebral infarction, have a headache, have a dizzy spell, insomnia, frequent micturition, QI and blood two decline bad disease, apoplexy sequela etc.
Clinical drug of the present invention is used result to show there is following advantage: it is raw material that (1) the present invention selects the natural edible-plant medicine of medicated diet homology, and each component meets pharmaceutical control law regulation.The medicine of the cardiovascular and cerebrovascular disease that utilizes the comprehensive function Hypertension of each taste Chinese medicine and cause thus has no side effect to human body is nontoxic, conventional peace for a long time.(2) medicine of the present invention is without bitterness sense, nutritious taking convenience.(3) light disease person can be used alone, and compared with serious symptom person, can combine use with other hypotensors, can greatly reduce or eliminate other complication, and have the immunity of enhancing body.
For showing medicine of the present invention, medical history, the state of an illness, age and Therapeutic Method and diagnostic criteria are observed and selected to the therapeutic effect of hypertension through 100 routine patient clinicals, the adult patients with hypertension of making a definite diagnosis.In the light-duty hypertension therapeutic memorandum of portion of delivering by 1993 Nian， World Health Organization (WHO)s and international hypertension association, proposed new hypertension horizontal classification standard, thought that systolic pressure is higher than 18.6 kPas (140 bold and unconstrained hydrargyrum are noted).Diastolic pressure can be examined as hypertension higher than 120 kPas (90 bold and unconstrained hydrargyrum are noted).At present domestic many with reference to this standard.Hypertension is by stages: according to the hypertension of World Health Organization (WHO) standard by stages, hypertension can be by having or not target organ internal organs such as () heart, brain, kidneys infringement and the extent of damage to be divided into following three phases:
The I phase: target organ is without organic lesion.(like sick non-disease, claiming borderline hypertension 141-159 person of outstanding talent hydrargyrum to note).
The II phase: at least meet in following three: (one) Electrocardioscopy has left ventricular hypertrophy or strain sign or x-ray, echocardiography to have left ventricle to expand sign; (2) arteria retina is general or limitation is narrow; (3) albuminuria or myocardium concentration slightly increase.
The III phase: meet in following 41: (one) left ventricular insufficiency; (2) renal failure (poisoning with metabolic); (3) intracranial hemorrhage (brain essence, the ventricles of the brain, subarachnoid hemorrhage); (4) retinal hemorrhage, ooze out and merge or nonjoinder papilloedema.
The present invention prevents and treats hypertension, and at the routine patients with hypertension of clinical observation 100, wherein to have 84 examples are I II phase patients, elder of age 72 years old, minimum 38 years old.Their Hypertension is used its clinical manifestation in medicine of the present invention 7 days to have the patient with sympotoms such as headache and dizzy, insomnia, frequent micturition, agitation, fatiguability to have the full disappearance of the above symptoms of 64 example to feel good, other 20 patients also all have symptom in various degree to improve, and 84 blood pressures all drop to normal level patient (140-90 person of outstanding talent hydrargyrum is noted following); III phase hypertension severe case 16 people, medication one to two course for the treatment of (30 days 1 courses for the treatment of) the most of patients state of an illness is taken a turn for the better, and has patient with angina pectoris pain relief number of times to reduce, and most of patients blood pressure is steadily normal; Minority malignant hypertension patient must Chinese medicine and western medicine combines use, and could to control blood pressure normal.
The specific embodiment:
The formula optimization weight proportion scope of preparation medicine of the present invention is Folium Ginkgo 8-20 part, Herb Gynostemmae Pentaphylli 5-10 part, Radix Salviae Miltiorrhizae 5-10 part, Fructus Crataegi slice 5-10 part, Radix Notoginseng 5-10 part, Cortex Moutan 5-10 part, Radix Ilicis Pubescentis 5-10 part, Rhizoma Chuanxiong 5-10 part, Radix Curcumae 5-10 part, Radix Angelicae Sinensis 5-10 part, Radix Polygoni Multiflori Preparata 5-10 part, Herba Epimedii 5-10 part, Fructus Ligustri Lucidi 5-10 part, Rhizoma Polygonati 5-10 part, Cortex Lycii 5-10 part, Radix Puerariae 5-20 part, Cortex Eucommiae 5-20 part, Herba Taxilli 5-20 part, Semen Cassiae 5-10 part, Herba Apocyni veneti 5-10 part, Rhizoma Alismatis 5-20 part, Pheretima 5-20 part, Ramulus Uncariae Cum Uncis 5-10 part, Spica Prunellae 5-10 part, Flos Chrysanthemi Indici 5-10 part, Plumula Nelumbinis 5-10 part, Herba Siegesbeckiae 5-10 part, Bulbus Allii Macrostemonis 5-10 part.
[method for making] can be prepared into any dosage form on pharmaceutics by prior art by pharmacopeia routine fashion.
Preferred 1. powders: powder feature and prescription
Powder is that one or several medicines are through being pulverized and mixed the powder preparation of evenly making.
The prescription of powder: powder must be pulverized appropriately, mix homogeneously, dosage accurately, steady quality, can bring into play due effect.General oral powder requires the fineness having to a certain degree to cross 80～100 mesh sieves, is applied to digestive tract and bursts sick powder by 120 mesh sieves.
The quality examination of powder has following several respects.
(1) uniformity: get test sample and put in right amount on photochemical paper, about 5cm tiles
2.Its surface is flattened, at bright place, observe, should present uniform color and luster, without decorative pattern, mottle.
(2) moisture: get test sample and measure by current edition < < Chinese Pharmacopoeia > > appendix aquametry, must not cross 9.0% except as otherwise herein provided.
(3) content uniformity: single dose, daily dose bag difference limit: be ± 15% below 0.9,0.1～0.5g is ± 10%, and 0.5～1.5g is ± 8%, 1.5～6g is that ± 7%, 6g is ± 5% above.Inspection technique: get 10 bags of test samples (bottle), respectively weighed every bag (bottle) content weight, compares with sign loading amount, no more than 2 bags (bottles) of overrun, and must not have a times of 1 bag of (bottle) overrun.
(4) sanitary inspection: press Ministry of Public Health < < drug inspection method > > and check, should be up to specification.
(5) powder: by the qualified weighing of above sixteen taste material processing assort, be dried, pulverize, sieve (80～100 order) mix homogeneously and get final product.
[usage and consumption] is oral, every day 2～3 times, each 10g warm water delivery service; Child takes the circumstances into consideration decrement.(or double and boil the powder of boiling medicine and merge after filtering residue sooner or later that each is once oral by decoction amount).
2. granule: soluble granule, Formulation water-soluble granular formulation.This granule adds water and can dissolve completely, and solution clear, without impurity such as breezes.
Manufacturing process is divided into: extract, refining, granulate, dry, granulate, quality examination, packaging and other steps.
(1) extract: most of raw materials extract with decocting method.Concrete operations are raw material to be cut into slices or section or grind to form end, by well-established law decoct, extracting juice stays slag, 3 times so repeatedly, juice is filtered and is merged, heating concentrated juice thick paste shape is standby.
(2) refining: thick paste is added to 95% ethanol of equivalent, mix all use, standing cold preservation is 12h at least, filter and reclaim after ethanol, then continue to be concentrated into paste.
(3) granulate: refined thick paste or dry cream fine powder are admixed to a certain amount of water soluble excipient, mix, then add the ethanol of normal concentration, afterwards by sieve (12～14 order) granulation on granulation machine.
The excipient of sol particle is mainly sucrose and dextrin.In sucrose with white sugar for well.With front dry.Pulverize and sieve and make Icing Sugar.In most cases, the ratio of thick paste and Icing Sugar be (1:2) (1:4)
(4) dry: with baking oven, drying room or far-infrared ray drying.While noting being dried, one wants rapidly, and two want temperature suitable, and temperature is controlled at 60～80 ℃ better.Dry run, is advisable with interior 2% with moisture Control in granule.
(5) granulate: after particle drying, may have the phenomenon of sticking together caking, need again sieve with oscillating granulator, make granule more even, the granule sifting out is more even, and the fine particle sifting out can be granulated again.
(6) packing: can pack with compound plastic bag, its advantage be thoroughly do not wet, airtight, granule is difficult for the phenomenon that the occurrence of wetness melts.
[usage and consumption] is oral, every day 2～3 times, and at every turn containing crude drug amount 20g (decoction pieces), warm boiled water, child takes the circumstances into consideration to reduce.
[packing is stored with specification] be powder 1.: use nontoxic aseptic plastic bag, every bag contains crude drug amount 10g (decoction pieces), and every 10 packed cartons sealings, leave ventilation, dry, shady and cool place in.(every bag of tolerance rate ± 2%).
[quality and health] powder, granule all will require to make product quality, health up to standard qualified in strict accordance with pharmaceutical control law.
Claims (3)
1. Hypertension and the medicine that causes thus cardiovascular and cerebrovascular disease, above disease causes ground arteriosclerosis thus, coronary heart disease, angina pectoris, arrhythmia, myocardial infarction, cerebral thrombosis, cerebral infarction, headache, have a dizzy spell, insomnia, frequent micturition, the two bad diseases of declining of QI and blood, apoplexy sequela etc., is characterized in that it is to make powder or granule (medicament of making by pharmacopeia routine fashion) by the raw material of following weight " part " proportioning, and its raw material is Folium Ginkgo 8-25 part, Herb Gynostemmae Pentaphylli 5-15 part, Radix Salviae Miltiorrhizae 5-15 part, Fructus Crataegi slice 5-15 part, Radix Notoginseng 5-15 part, Cortex Moutan 5-15 part, Radix Ilicis Pubescentis 5-15 part, Rhizoma Chuanxiong 5-15 part, Radix Curcumae 5-15 part, Radix Angelicae Sinensis 5-15 part, Radix Polygoni Multiflori Preparata 5-15 part, Herba Epimedii 5-15 part, Fructus Ligustri Lucidi 5-15 part, Rhizoma Polygonati 5-15 part, Cortex Lycii 5-15 part, Radix Puerariae 5-15 part, Rhizoma Alismatis 5-15 part, Pheretima 5-15 part, Cortex Eucommiae 5-15 part, Herba Taxilli 5-15 part, Semen Cassiae 5-15 part, Herba Apocyni veneti 5-15 part, Ramulus Uncariae Cum Uncis 5-15 part, Spica Prunellae 5-15 part, Flos Chrysanthemi Indici 5-15 part, Plumula Nelumbinis 5-15 part, Herba Siegesbeckiae 5-15 part, Bulbus Allii Macrostemonis 5-15 part.
2. Hypertension according to claim 1 and the medicine that causes thus cardiovascular and cerebrovascular disease, above disease causes ground arteriosclerosis thus, coronary heart disease, angina pectoris, arrhythmia, myocardial infarction, cerebral thrombosis, cerebral infarction, headache, have a dizzy spell, insomnia, frequent micturition, the two bad diseases of declining of QI and blood, apoplexy sequela etc., is characterized in that it is to make powder or granule (medicament of making by pharmacopeia routine fashion) by the raw material of following weight " part " proportioning, and its raw material is Folium Ginkgo 8-20 part, Herb Gynostemmae Pentaphylli 5-10 part, Radix Salviae Miltiorrhizae 5-10 part, Fructus Crataegi slice 5-10 part, Radix Notoginseng 5-10 part, Cortex Moutan 5-10 part, Radix Ilicis Pubescentis 5-10 part, Rhizoma Chuanxiong 5-10 part, Radix Curcumae 5-10 part, Radix Angelicae Sinensis 5-10 part, Radix Polygoni Multiflori Preparata 5-10 part, Herba Epimedii 5-10 part, Fructus Ligustri Lucidi 5-10 part, Rhizoma Polygonati 5-10 part, Cortex Lycii 5-10 part, Radix Puerariae 5-10 part, Rhizoma Alismatis 5-10 part, Pheretima 5-10 part, Cortex Eucommiae 5-10 part, Herba Taxilli 5-10 part, Semen Cassiae 5-10 part, Herba Apocyni veneti 5-10 part, Ramulus Uncariae Cum Uncis 5-10 part, Spica Prunellae 5-10 part, Flos Chrysanthemi Indici 5-10 part, Plumula Nelumbinis 5-10 part, Herba Siegesbeckiae 5-10 part, Bulbus Allii Macrostemonis 5-10 part.
3. Hypertension according to claim 2 and the medicine that causes thus cardiovascular and cerebrovascular disease, above disease causes ground arteriosclerosis thus, coronary heart disease, angina pectoris, arrhythmia, myocardial infarction, cerebral thrombosis, cerebral infarction, headache, have a dizzy spell, insomnia, frequent micturition, the two bad diseases of declining of QI and blood, apoplexy sequela etc., is characterized in that it is to make powder or granule (medicament of making by pharmacopeia routine fashion) by the raw material of following weight " part " proportioning, and its raw material is 20 parts of Folium Ginkgos, 10 parts of Herb Gynostemmae Pentaphylli, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Fructus Crataegi slice, 10 parts of Radix Notoginseng, 10 parts of Cortex Moutans, 10 parts of Radix Ilicis Pubescentiss, 10 parts of Rhizoma Chuanxiongs, 10 parts of Radix Curcumaes, 10 parts of Radix Angelicae Sinensis, 10 parts of Radix Polygoni Multiflori Preparata, 10 parts of Herba Epimedii, 10 parts of Fructus Ligustri Lucidi, 10 parts of Rhizoma Polygonatis, 10 parts of Cortex Lycii, 10 parts of Radix Puerariaes, 10 parts of Rhizoma Alismatis, 10 parts of Pheretimas, 10 parts of the Cortexs Eucommiae, 10 parts of Herba Taxillis, 10 parts of Semen Cassiaes, 10 parts of Herba Apocyni venetis, 10 parts of Ramulus Uncariae Cum Uncis, 10 parts of Spica Prunellaes, 10 parts of Flos Chrysanthemi Indicis, 10 parts of Plumula Nelumbiniss, 10 parts of Herba Siegesbeckiaes, 10 parts of Bulbus Allii Macrostemonis.
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104206594A (en) * | 2014-08-27 | 2014-12-17 | 青岛恒波仪器有限公司 | Herba Taxilli health-care tea capable of lowering blood pressure and blood lipid and preparation method thereof |
| CN105012381A (en) * | 2015-08-07 | 2015-11-04 | 高努 | Lipid lowering and thrombolysis combination and preparation method of food and medicine capsule thereof |
| CN105287929A (en) * | 2015-11-10 | 2016-02-03 | 王冬梅 | Spleen invigorating and qi supplementing prescription for treating atherosclerosis and preparation method thereof |
| CN105287933A (en) * | 2015-11-10 | 2016-02-03 | 王冬梅 | Traditional Chinese medicine preparation capable of treating arteriosclerosis and invigorating spleen and supplementing qi and preparation method thereof |
| CN105287910A (en) * | 2015-11-10 | 2016-02-03 | 王冬梅 | Anti-atherosclerosis preparation and preparation method |
| CN105727009A (en) * | 2014-12-11 | 2016-07-06 | 广西大学 | Traditional Chinese medicine composition for reducing blood pressure |
| CN106474430A (en) * | 2016-12-01 | 2017-03-08 | 辽东学院 | Treatment hypertensive patients medicaments for coronary disease preparation and preparation method thereof |
| US11369653B2 (en) * | 2018-04-17 | 2022-06-28 | Hongzhang Jia | Traditional Chinese medicine composition for treating cardiovascular and cerebrovascular disease, preparation method therefor and use thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101274084A (en) * | 2007-12-18 | 2008-10-01 | 秦庆吉 | Medicament for curing hypertension, hyperlipemia and complication thereof |
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2013
- 2013-11-06 CN CN201310541754.3A patent/CN103623341A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101274084A (en) * | 2007-12-18 | 2008-10-01 | 秦庆吉 | Medicament for curing hypertension, hyperlipemia and complication thereof |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104206594A (en) * | 2014-08-27 | 2014-12-17 | 青岛恒波仪器有限公司 | Herba Taxilli health-care tea capable of lowering blood pressure and blood lipid and preparation method thereof |
| CN105727009A (en) * | 2014-12-11 | 2016-07-06 | 广西大学 | Traditional Chinese medicine composition for reducing blood pressure |
| CN105012381A (en) * | 2015-08-07 | 2015-11-04 | 高努 | Lipid lowering and thrombolysis combination and preparation method of food and medicine capsule thereof |
| CN105287929A (en) * | 2015-11-10 | 2016-02-03 | 王冬梅 | Spleen invigorating and qi supplementing prescription for treating atherosclerosis and preparation method thereof |
| CN105287933A (en) * | 2015-11-10 | 2016-02-03 | 王冬梅 | Traditional Chinese medicine preparation capable of treating arteriosclerosis and invigorating spleen and supplementing qi and preparation method thereof |
| CN105287910A (en) * | 2015-11-10 | 2016-02-03 | 王冬梅 | Anti-atherosclerosis preparation and preparation method |
| CN106474430A (en) * | 2016-12-01 | 2017-03-08 | 辽东学院 | Treatment hypertensive patients medicaments for coronary disease preparation and preparation method thereof |
| US11369653B2 (en) * | 2018-04-17 | 2022-06-28 | Hongzhang Jia | Traditional Chinese medicine composition for treating cardiovascular and cerebrovascular disease, preparation method therefor and use thereof |
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