CN105287910A - Anti-atherosclerosis preparation and preparation method - Google Patents
Anti-atherosclerosis preparation and preparation method Download PDFInfo
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Abstract
The invention discloses an anti-atherosclerosis preparation which is mainly prepared from, by mass parts, 8-12 parts of polygonum cuspidatum, 6-13 parts of cortex lycii radicis, 7-11 parts of China rose, 5-12 parts of aglaia odorata, 8-14 parts of bennet, 4-9 parts of apocynum venetum, 6-11 parts of syneilesis aconitifolia, 9-13 parts of ficus formosana root, 7-12 parts of biondia henryi, 6-10 parts of tea, 9-14 parts of lance asiabell root, 7-13 parts of cynachum uilfordii hemsl, 5-11 parts of flemingia philippinensis and 8-13 parts of mesona chinensis. The prepared product is good in curative effect, has no adverse effect and is high in safety and extensive in applicability. The anti-atherosclerosis preparation is prepared according to the traditional Chinese medicine syndrome differentiation principle and has effects of removing blood stasis, activating blood, dissipating phlegm, calming wind, strengthening the spleen and eliminating dampness. The anti-atherosclerosis preparation is prepared from traditional Chinese medicine plants, is low in cost and can relieve burden on patients.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of atherosclerosis preparation and method for making.
Background technology
Atherosclerosis is most important one common in one group of arteriosclerotic angiopathy, is characterized in getting involved arterial disease from inner membrance.General first have that lipid and compound saccharide gather, hemorrhage and thrombosis, proliferation of fibrous tissue and calcinosis, and having medial transformation gradually and calcification; pathological changes often involves elasticity and large medium muscular artery; be enough to obstructing arterial chamber once develop into, then the tissue supplied of this tremulous pulse or organ are by ischemia or necrosis.Because the lipid outward appearance gathered at endarterium is yellow medicated porridge sample, be therefore called atherosclerosis.Atherosclerosis is modal and have the disease of hazardness most, is arteriosclerotic one, and large, medium-sized artery inner membrance occurs, containing the yellow substance of cholesterol, class fat etc., how being caused by fat metabolic disturbance, neural blood vessel functional disorder.Often cause thrombosis, blood supply disorder etc.Atherosclerosis is more common in the male of more than 40 years old and the women after menopause.Primary disease is often with hypertension, hypercholesterolemia or diabetes etc.Brain worker is more common, very large to health of people harm, for old people mainly dies of illness one of reason.
Atherosclerotic symptom depends mainly on the degree of ischemia of vascular lesion and afflicted organ, atherosclerosis of aorta is often asymptomatic, coronary atherosclerosis person, if caliber is narrow reach more than 75%, then can there is angina pectoris, myocardial infarction, arrhythmia, even die suddenly.Cerebral arteriosclerosis can cause cerebral ischemia, brain atrophy, or causes rupture of blood vessel in brain hemorrhage, and atherosclerotic renal artery stenosis often causes nocturia, intractable hypertension, severe patient to have renal insufficiency.After superior mesenteric atherosclerosis can show as heavy meal, stomachache such as to be had blood in stool at the symptom.Lower limb atherosclerosis causes lumen of vessels Serious Stenosis person can occur intermittent claudication, pulsation of foot dorsal artery disappearance, and severe patient even gangrene can occur.
Publication No. CN102670893A(application number 201210175181.2) Chinese patent literature disclose one and treat atherosclerotic Chinese medicine composition, crude drug has Radix Astragali 50-70, Radix Angelicae Sinensis 8-12, Radix Paeoniae Rubra 8-12, Pheretima 8-12, Rhizoma Chuanxiong 8-12, Flos Carthami 5-7, Semen Persicae 8-12, Rhizoma Pinelliae Preparatum 8-12, Fructus Aurantii 8-12.Publication No. CN103550624A(application number 201310524895.4) Chinese patent literature disclose a kind of Chinese medicine preparation for the treatment of atherosclerosis and coronary heart disease, primary raw material is Radix Angelicae Sinensis 30 parts, Rhizoma Chuanxiong 15 parts, the Radix Paeoniae Alba 18 parts, 30 parts, Fructus Hordei Germinatus, 12 parts, Flos Carthami, Thallus Laminariae (Thallus Eckloniae) 12 parts, Herba Menthae 10 parts, Folium Fumicis Dentati 30 parts, Rhizoma Phragmitis 30 parts.Publication No. CN102716428A(application number 201210230210.0) Chinese patent literature disclose a kind of antiatherogenic Chinese medicine composition, comprise Radix Polygoni Multiflori Preparata 10-20 weight portion, Rhizoma Alismatis 10-20 weight portion, Semen Cassiae (parched) 10-20 weight portion, RADIX CURCUMAE 5-15 weight portion.
Treat atherosclerotic Western medicine and have blood lipid-lowering medicine, antiplatelet drug, hirudin etc., some western medicine effects are unsatisfactory, cure the symptoms, not the disease, Chinese medicine can dialectical treatmert, treats this disease and has certain advantage, and safety is high, a kind of Chinese medicine formula for the treatment of this disease therefore can be developed.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of evident in efficacy, take safe atherosclerosis preparation and method for making.
Technical scheme of the present invention is:
A kind of atherosclerosis preparation, is prepared from primarily of following bulk drugs, is mass parts: Rhizoma Polygoni Cuspidati 8-12, Cortex Lycii 6-13, Flos Rosae Chinensis 7-11, Flos Aglaiae Odoratae 5-12, Fructus Adinae 8-14, Herba Apocyni veneti 4-9, Herba Syneilesis Aconitifoliae 6-11, Radix Fici beecheyanae 9-13, Herba Biondiae henryi 7-12, Folium Camelliae sinensis 6-10, Radix Codonopsis lanceolatae 9-14, Radix cynanchi wilfordii 7-13, Radix Flemingiae Philippinensis 5-11, Herba mesonae chinensis 8-13.
In preferred scheme, Rhizoma Polygoni Cuspidati 9-11, Cortex Lycii 8-11, Flos Rosae Chinensis 8-10, Flos Aglaiae Odoratae 7-10, Fructus Adinae 10-12, Herba Apocyni veneti 5-8, Herba Syneilesis Aconitifoliae 7-10, Radix Fici beecheyanae 10-12, Herba Biondiae henryi 8-11, Folium Camelliae sinensis 7-9, Radix Codonopsis lanceolatae 10-13, Radix cynanchi wilfordii 8-12, Radix Flemingiae Philippinensis 7-9, Herba mesonae chinensis 9-12.
Be more preferably, Rhizoma Polygoni Cuspidati 10, Cortex Lycii 9.5, Flos Rosae Chinensis 9, Flos Aglaiae Odoratae 8.5, Fructus Adinae 11, Herba Apocyni veneti 6.5, Herba Syneilesis Aconitifoliae 8.5, Radix Fici beecheyanae 11, Herba Biondiae henryi 9.5, Folium Camelliae sinensis 8, Radix Codonopsis lanceolatae 11.5, Radix cynanchi wilfordii 10, Radix Flemingiae Philippinensis 8, Herba mesonae chinensis 10.5.
The preparation method of the decoction of described a kind of atherosclerosis preparation, step is as follows:
(1) get Radix Codonopsis lanceolatae and clean section, add water together with Flos Aglaiae Odoratae with Oryza glutinosa with boiling, when Oryza glutinosa boils to half ripe, Guan Huo, pulls Radix Codonopsis lanceolatae and Flos Aglaiae Odoratae out, and removing Oryza glutinosa, is stained with wine and dries;
(2) get Herba Syneilesis Aconitifoliae, Radix Fici beecheyanae and Herba Biondiae henryi yellow wine and soak 20 minutes, take out, be placed in Steam by water bath in bamboo drawer saturating, take out, dry in the air cool, section or cutting, be placed in frying pan, and moderate heat is fried to surperficial yellowish-brown, takes out, dries in the air cool;
(3) get Folium Camelliae sinensis and add decocting in water, little fire continues after boiling to boil 10 minutes, crosses and filters Folium Camelliae sinensis, collects filtrate, Radix cynanchi wilfordii and Radix Flemingiae Philippinensis is cleaned, and boils and exhausts to water, take out, dry with filtrate;
(4) together with Rhizoma Polygoni Cuspidati, Cortex Lycii, Flos Rosae Chinensis, Fructus Adinae and Herba mesonae chinensis and step (1) (2) (3) made crude drug, decocting in water is added, amount of water is 6 times of boiled crude drug quality, big fire is boiled rear little fire and is boiled, and filter, filtering residue adds water and boils, close fire and add Herba Apocyni veneti in first 10 minutes, filter, merge twice gained filtrate, be condensed into 1/2 of original volume, sterilizing, obtains decoction.
The preparation method of described a kind of atherosclerosis preparation decoction, step (4) big fire is boiled rear little fire and is boiled 28-34 minute (preferred, little fire boils 30-32 minute; Be more preferably, little fire boils 31 minutes).
The preparation method of the soft extract of described a kind of atherosclerosis preparation, step is as follows:
(1) get Radix Codonopsis lanceolatae and clean section, add water together with Flos Aglaiae Odoratae with Oryza glutinosa with boiling, when Oryza glutinosa boils to half ripe, Guan Huo, pulls Radix Codonopsis lanceolatae and Flos Aglaiae Odoratae out, and removing Oryza glutinosa, is stained with wine and dries;
(2) get Herba Syneilesis Aconitifoliae, Radix Fici beecheyanae and Herba Biondiae henryi yellow wine and soak 20 minutes, take out, be placed in Steam by water bath in bamboo drawer saturating, take out, dry in the air cool, section or cutting, be placed in frying pan, and moderate heat is fried to surperficial yellowish-brown, takes out, dries in the air cool;
(3) get Folium Camelliae sinensis and add decocting in water, little fire continues after boiling to boil 10 minutes, crosses and filters Folium Camelliae sinensis, collects filtrate, Radix cynanchi wilfordii and Radix Flemingiae Philippinensis is cleaned, and boils and exhausts to water, take out, dry with filtrate;
(4) Rhizoma Polygoni Cuspidati, Cortex Lycii, Fructus Adinae and Herba mesonae chinensis and step (1) (2) made crude drug are added decocting in water together with step (3) made Radix Flemingiae Philippinensis, decoct twice, each amount of water is 6 times of boiled crude drug quality, big fire is boiled rear little fire and is boiled 28-34 minute (preferred, little fire boils 30-32 minute; Be more preferably, little fire boils 31 minutes), filter, merge twice gained filtrate, be condensed into 1/2 of original volume;
(5) Flos Rosae Chinensis, Herba Apocyni veneti were pulverized 300 mesh sieves together with step (3) made Radix cynanchi wilfordii, and joined in step (4) made concentrated solution, with vinegar and starch, be brewed into thick paste, obtain soft extract.
The preparation method of described a kind of atherosclerosis preparation soft extract, the relative density of step (5) thick paste is 1.26-1.32(60 DEG C) (preferred, the relative density of thick paste is 1.28-1.30; Be more preferably, the relative density of thick paste is 1.29).
The preparation method of the granule of described a kind of atherosclerosis preparation, step is as follows:
(1) get Radix Codonopsis lanceolatae and clean section, add water together with Flos Aglaiae Odoratae with Oryza glutinosa with boiling, when Oryza glutinosa boils to half ripe, Guan Huo, pulls Radix Codonopsis lanceolatae and Flos Aglaiae Odoratae out, and removing Oryza glutinosa, is stained with wine and dries;
(2) get Herba Syneilesis Aconitifoliae, Radix Fici beecheyanae and Herba Biondiae henryi yellow wine and soak 20 minutes, take out, be placed in Steam by water bath in bamboo drawer saturating, take out, dry in the air cool, section or cutting, be placed in frying pan, and moderate heat is fried to surperficial yellowish-brown, takes out, dries in the air cool;
(3) get Folium Camelliae sinensis and add decocting in water, little fire continues after boiling to boil 10 minutes, crosses and filters Folium Camelliae sinensis, collects filtrate, Radix cynanchi wilfordii and Radix Flemingiae Philippinensis is cleaned, and boils and exhausts to water, take out, dry with filtrate;
(4) together with Rhizoma Polygoni Cuspidati, Cortex Lycii, Flos Rosae Chinensis, Fructus Adinae, Herba Apocyni veneti and Herba mesonae chinensis and step (1) (2) (3) made crude drug, add decocting in water, decoct three times, big fire is boiled rear little fire and is boiled 28-34 minute (preferred, little fire boils 30-32 minute; Be more preferably, little fire boils 31 minutes), filter, merge three gained filtrates;
(5) step (4) made filtrate is concentrated, dry, pulverize into fine powder, add adjuvant, make granule of uniform size, sterilizing, obtain granule.
The preparation method of described a kind of atherosclerosis preparation granules agent, step (4) decocts three times, and the 6-8 that each amount of water is boiled crude drug quality is (preferred, each amount of water is 7 times of boiled crude drug quality) doubly.
The preparation method of the powder of described a kind of atherosclerosis preparation, step is as follows:
(1) get Radix Codonopsis lanceolatae and clean section, add water together with Flos Aglaiae Odoratae with Oryza glutinosa with boiling, when Oryza glutinosa boils to half ripe, Guan Huo, pulls Radix Codonopsis lanceolatae and Flos Aglaiae Odoratae out, and removing Oryza glutinosa, is stained with wine and dries;
(2) get Herba Syneilesis Aconitifoliae, Radix Fici beecheyanae and Herba Biondiae henryi yellow wine and soak 20 minutes, take out, be placed in Steam by water bath in bamboo drawer saturating, take out, dry in the air cool, section or cutting, be placed in frying pan, and moderate heat is fried to surperficial yellowish-brown, takes out, dries in the air cool;
(3) get Folium Camelliae sinensis and add decocting in water, little fire continues after boiling to boil 10 minutes, crosses and filters Folium Camelliae sinensis, collects filtrate, Radix cynanchi wilfordii and Radix Flemingiae Philippinensis is cleaned, and boils and exhausts to water, take out, dry with filtrate;
(4) together with Rhizoma Polygoni Cuspidati, Cortex Lycii, Flos Rosae Chinensis, Fructus Adinae, Herba Apocyni veneti and Herba mesonae chinensis and step (1) (2) (3) made crude drug, decocting in water is added, decoct three times, each amount of water is 7 times of boiled crude drug quality, big fire is boiled rear little fire and is boiled 28-34 minute (preferred, little fire boils 30-32 minute; Be more preferably, little fire boils 31 minutes), filter, merge three gained filtrates;
(5) step (4) made filtrate concentrated, dry, pulverize into fine powder, add cane sugar powder mixing, sterilizing, obtains powder.
The preparation method of described a kind of atherosclerosis preparation powder, step (5) was pulverized 140-180 mesh sieve and (preferably, was pulverized 150-170 mesh sieve; Be more preferably, pulverized 160 mesh sieves).
A kind of atherosclerosis preparation recipe science provided by the invention, accurately dialectical, preparation is simple.In addition, excellent results of the present invention also shows:
1, products made thereby good effect of the present invention, have no adverse reaction, safety is high, and the suitability is wide;
2, this prescription controls principle development according to Chinese herb decoction opinion, has the effects such as promoting blood circulation by removing blood stasis, eliminating phlegm and calming wind, the spleen strengthening and damp drying;
3, the present invention selects Chinese medicinal plant to make, and cost is low, can relieve patient ' s burden.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Rhizoma Polygoni Cuspidati: base is former: be the rhizome of polygonaceae plant Rhizoma Polygoni Cuspidati.Nature and flavor: micro-hardship, is slightly cold.Gui Jing: return liver, gallbladder, lung meridian.Function cures mainly: expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.For arthralgia, jaundice due to damp-heat, amenorrhea, lump in the abdomen, burn due to hot liquid or fire, injury from falling down, carbuncle sore tumefacting virus, cough with copious phlegm.
Cortex Lycii: base is former: be the root bark of eggplant kind of plant Fructus Lycii etc.Nature and flavor: sweet, cold.Gui Jing: enter lung, liver, kidney channel.Function cures mainly: heat clearing away, removing heat from blood.Control asthenia hectic fever night sweat, lung-heat cough with asthma, spit blood, epistaxis, stranguria with blood, quenches one's thirst, hypertension, carbuncle, malignant boil.
Flos Rosae Chinensis: base is former: for the half-open of rosaceous plant Flos Rosae Chinensis is let off fireworks.Nature and flavor: sweet, temperature.Gui Jing: return Liver Channel.Function cures mainly: promoting blood flow to regulate menstruation, loose poison detumescence.For menoxenia, dysmenorrhea, carbuncle furuncle and phyma poison, tuberculous lymphadenitis (non-diabrosis).
Flos Aglaiae Odoratae: base is former: be flower or the branch and leaf of Meliaceae plant Flos Aglaiae Odoratae.Nature and flavor: acrid-sweet flavor, property is put down.Gui Jing: enter lung, stomach, liver three warp.Function cures mainly: resolving depression alleviating distention in middle-JIAO, expedites the emergence of, relieving alcoholic intoxication, lung heat clearing, and wake up the head, only excessive thirst.Control chest and diaphragm distension uncomfortable, dysphagic from the beginning of, cough and dizzy.
Fructus Adinae: base is former: be the herb of rosaceous plant Japanese avens.Nature and flavor: bitter, puckery, cool.Function cures mainly: tonify deficiency kidney tonifying, promoting blood circulation and detoxication.Control and have a dizzy spell.Myasthenia of limbs, seminal emission sexual impotence, exterior deficiency is caught a cold, and cough is spitted blood, asthenia cold abdominalgia, menoxenia, and skin ulcer swells, fracture.
Herba Apocyni veneti: base is former: be the herb of apocynaceae plant Herba Apocyni veneti.Nature and flavor: sweetness and bitterness are cool.Function cures mainly: relieve inflammation or internal heat, blood pressure lowering, heart tonifying, diuresis.Control heart disease, hypertension, neurasthenia, hepatitis abdominal distention, nephritis edema.
Herba Syneilesis Aconitifoliae: base is former: be root or the herb of feverfew Herba Syneilesis Aconitifoliae.Nature and flavor: pungent, tepor.Function cures mainly: wind-damp dispelling, relaxing muscles and tendons to promote blood circulation, pain relieving.For lumbago and skelalgia, traumatic injury.
Radix Fici beecheyanae: base is former: be the root of moraceae plants Fructus Fici Beecheyanae.Nature and flavor: sweet, acrid, warm.Gui Jing: enter lung, spleen, kidney three warp.Function cures mainly: invigorating the spleen and benefiting QI, invigorates blood circulation, expelling wind and removing dampness.Control overstrain weak, lack of appetite, breast is difficult, this tune of menstruation, insufficiency of the spleen leucorrhea, proctoptosis, rheumatism.
Herba Biondiae henryi: base is former: be the whole herb with root of Luo Cao section plant biondia hennriyi.Nature and flavor: light, temperature.Function cures mainly: relaxing muscles and tendons to promote blood circulation, regulates the flow of vital energy and dispels the wind.Control traumatic injury, lower limb cold type of pain is numb, rheumatism numb hand and foot, toothache.
Folium Camelliae sinensis: base is former: be the bud-leaf of plant of theaceae tea.Nature and flavor: bitter sweet, cool.Gui Jing: enter the heart, lung, stomach warp.Function cures mainly: refresh oneself, and relieving thirst and restlessness is reduced phlegm, and helps digestion, diuresis, removing toxic substances.Control headache, blurred vision, kind sleeping of sleeping, restlessness and thirst, food stagnation expectorant is stagnant, malaria, dysentery more.
Radix Codonopsis lanceolatae: base is former: be the root of Campanulaceae Lac caprae seu ovis.Nature and flavor: Gan Xin are flat.Function cures mainly: detumescence, and removing toxic substances, evacuation of pus, eliminates the phlegm, lactogenic.Control lung abscess, acute mastitis, acute appendicitis, toxic swelling, scrofula, throat moth, breast is few, leucorrhea.
Radix cynanchi wilfordii: base is former: be the tuber of asclepiadaceae plant cynanchum auriculatum Royle.Nature and flavor: sweetness and bitterness are flat, nontoxic.Function cures mainly: yin nourishing tonify deficiency, strengthening the spleen to promote digestion.Control deficient impairment caused by overstrain, dysentery, infantile malnutrition, have a stomachache glutted, leucorrhea, skin ulcer tinea.
Radix Flemingiae Philippinensis: base is former: be the root of leguminous plant Flemingia philippinensis.Nature and flavor: sweet, tepor are flat.Function cures mainly: wind-damp dispelling, strong waist knee joint.For rheumatic arthritis, lumbago and skelalgia, lumbar muscle strain, leucorrhea, traumatic injury.
Herba mesonae chinensis: base is former: be the herb of labiate Herba mesonae chinensis.Nature and flavor: sweet, light, cool.Function cures mainly: clearing away heat-damp and promoting diuresis, removing heat from blood expelling summer-heat.For acute rheumatic arthritis, hypertension, heatstroke, flu, jaundice, acute nephritis, diabetes.
embodiment 1a kind of atherosclerosis preparation, is prepared from (every part of 10g) primarily of following bulk drugs: Rhizoma Polygoni Cuspidati 8 parts, Cortex Lycii 6 parts, Flos Rosae Chinensis 7 parts, Flos Aglaiae Odoratae 5 parts, Fructus Adinae 8 parts, Herba Apocyni veneti 4 parts, Herba Syneilesis Aconitifoliae 6 parts, Radix Fici beecheyanae 9 parts, Herba Biondiae henryi 7 parts, Folium Camelliae sinensis 6 parts, Radix Codonopsis lanceolatae 9 parts, Radix cynanchi wilfordii 7 parts, Radix Flemingiae Philippinensis 5 parts, Herba mesonae chinensis 8 parts.
The preparation method of above-mentioned a kind of atherosclerosis preparation decoction is:
(1) get Radix Codonopsis lanceolatae and clean section, add water together with Flos Aglaiae Odoratae with Oryza glutinosa with boiling, when Oryza glutinosa boils to half ripe, Guan Huo, pulls Radix Codonopsis lanceolatae and Flos Aglaiae Odoratae out, and removing Oryza glutinosa, is stained with wine and dries;
(2) get Herba Syneilesis Aconitifoliae, Radix Fici beecheyanae and Herba Biondiae henryi yellow wine and soak 20 minutes, take out, be placed in Steam by water bath in bamboo drawer saturating, take out, dry in the air cool, section or cutting, be placed in frying pan, and moderate heat is fried to surperficial yellowish-brown, takes out, dries in the air cool;
(3) get Folium Camelliae sinensis and add decocting in water, little fire continues after boiling to boil 10 minutes, crosses and filters Folium Camelliae sinensis, collects filtrate, Radix cynanchi wilfordii and Radix Flemingiae Philippinensis is cleaned, and boils and exhausts to water, take out, dry with filtrate;
(4) together with Rhizoma Polygoni Cuspidati, Cortex Lycii, Flos Rosae Chinensis, Fructus Adinae and Herba mesonae chinensis and step (1) (2) (3) made crude drug, decocting in water is added, amount of water is 6 times of boiled crude drug quality, big fire is boiled rear little fire and is boiled 31 minutes, and filter, filtering residue adds water and boils, close fire and add Herba Apocyni veneti in first 10 minutes, filter, merge twice gained filtrate, be condensed into 1/2 of original volume, sterilizing, obtains decoction.
embodiment 2a kind of atherosclerosis preparation, is prepared from (every part of 10g) primarily of following bulk drugs: Rhizoma Polygoni Cuspidati 12 parts, Cortex Lycii 13 parts, Flos Rosae Chinensis 11 parts, Flos Aglaiae Odoratae 12 parts, Fructus Adinae 14 parts, Herba Apocyni veneti 9 parts, Herba Syneilesis Aconitifoliae 11 parts, Radix Fici beecheyanae 13 parts, Herba Biondiae henryi 12 parts, Folium Camelliae sinensis 10 parts, Radix Codonopsis lanceolatae 14 parts, Radix cynanchi wilfordii 13 parts, Radix Flemingiae Philippinensis 11 parts, Herba mesonae chinensis 13 parts.
A kind of preparation method of atherosclerosis preparation soft extract is:
(1) get Radix Codonopsis lanceolatae and clean section, add water together with Flos Aglaiae Odoratae with Oryza glutinosa with boiling, when Oryza glutinosa boils to half ripe, Guan Huo, pulls Radix Codonopsis lanceolatae and Flos Aglaiae Odoratae out, and removing Oryza glutinosa, is stained with wine and dries;
(2) get Herba Syneilesis Aconitifoliae, Radix Fici beecheyanae and Herba Biondiae henryi yellow wine and soak 20 minutes, take out, be placed in Steam by water bath in bamboo drawer saturating, take out, dry in the air cool, section or cutting, be placed in frying pan, and moderate heat is fried to surperficial yellowish-brown, takes out, dries in the air cool;
(3) get Folium Camelliae sinensis and add decocting in water, little fire continues after boiling to boil 10 minutes, crosses and filters Folium Camelliae sinensis, collects filtrate, Radix cynanchi wilfordii and Radix Flemingiae Philippinensis is cleaned, and boils and exhausts to water, take out, dry with filtrate;
(4) Rhizoma Polygoni Cuspidati, Cortex Lycii, Fructus Adinae and Herba mesonae chinensis and step (1) (2) made crude drug are added decocting in water together with step (3) made Radix Flemingiae Philippinensis, decoct twice, each amount of water is 6 times of boiled crude drug quality, big fire is boiled rear little fire and is boiled 31 minutes, filter, merge twice gained filtrate, be condensed into 1/2 of original volume;
(5) Flos Rosae Chinensis, Herba Apocyni veneti were pulverized 300 mesh sieves together with step (3) made Radix cynanchi wilfordii, and joined in step (4) made concentrated solution, with vinegar and starch, being brewed into relative density is 1.29(60 DEG C) thick paste, obtain soft extract.
Model case: xxx, female, 64 years old.Main suit: suffer from hypertension 5 years, started before half a year to occur the intermittent pain of two lower limb, calf acid is heavy weak, myalgia, forgetful, dizzy, after there is intermittent claudication, lower limbs edema, blue, biped is not warm, is afraid of cold, examination in hospital, be diagnosed as lower limb atherosclerosis obliterans companion cardiovascular and cerebrovascular vessel atherosclerosis, hospitalization, symptom takes a turn for the better to some extent, but do not eliminate completely, the backward traditional Chinese medical science is sought medical advice always.
Take a kind of atherosclerosis preparation of the present embodiment gained soft extract, every day 2 times, each 10ml, warm boiled water, 30 days courses for the treatment of.After taking a course for the treatment of, lower limb pain alleviates, and fear of cold takes a turn for the better, and after taking two courses for the treatment of, dizziness obviously alleviates, and numbness of lower limbs, pain are obviously improved, and after taking four courses for the treatment of, all diseases disappear entirely, and memory improves, and consolidates and takes a course for the treatment of, follows up a case by regular visits to without recurrence after 1 year.
embodiment 3a kind of atherosclerosis preparation, is prepared from (every part of 10g) primarily of following bulk drugs: Rhizoma Polygoni Cuspidati 9 parts, Cortex Lycii 8 parts, Flos Rosae Chinensis 8 parts, Flos Aglaiae Odoratae 7 parts, Fructus Adinae 10 parts, Herba Apocyni veneti 5 parts, Herba Syneilesis Aconitifoliae 7 parts, Radix Fici beecheyanae 10 parts, Herba Biondiae henryi 8 parts, Folium Camelliae sinensis 7 parts, Radix Codonopsis lanceolatae 10 parts, Radix cynanchi wilfordii 8 parts, Radix Flemingiae Philippinensis 7 parts, Herba mesonae chinensis 9 parts.
The preparation method of a kind of atherosclerosis preparation granules agent is:
(1) get Radix Codonopsis lanceolatae and clean section, add water together with Flos Aglaiae Odoratae with Oryza glutinosa with boiling, when Oryza glutinosa boils to half ripe, Guan Huo, pulls Radix Codonopsis lanceolatae and Flos Aglaiae Odoratae out, and removing Oryza glutinosa, is stained with wine and dries;
(2) get Herba Syneilesis Aconitifoliae, Radix Fici beecheyanae and Herba Biondiae henryi yellow wine and soak 20 minutes, take out, be placed in Steam by water bath in bamboo drawer saturating, take out, dry in the air cool, section or cutting, be placed in frying pan, and moderate heat is fried to surperficial yellowish-brown, takes out, dries in the air cool;
(3) get Folium Camelliae sinensis and add decocting in water, little fire continues after boiling to boil 10 minutes, crosses and filters Folium Camelliae sinensis, collects filtrate, Radix cynanchi wilfordii and Radix Flemingiae Philippinensis is cleaned, and boils and exhausts to water, take out, dry with filtrate;
(4) together with Rhizoma Polygoni Cuspidati, Cortex Lycii, Flos Rosae Chinensis, Fructus Adinae, Herba Apocyni veneti and Herba mesonae chinensis and step (1) (2) (3) made crude drug, decocting in water is added, decoct three times, each amount of water is 7 times of boiled crude drug quality, big fire is boiled rear little fire and is boiled 31 minutes, filter, merge three gained filtrates;
(5) step (4) made filtrate is concentrated, dry, pulverize into fine powder, add adjuvant, make granule of uniform size, sterilizing, obtain granule.
Model case: xxx, man, 76 years old.Suffer from hyperlipidemia 18 years, be interrupted and take hypolipidemic, often feel dizzy, numbness of hand nearly half a year, originally symptom is not obvious payes attention to, and finds that left limb activity is unfavorable, slight facial hemiparalysis after getting up two months ago, dizzy brain covers, examination in hospital, the multiple lacunar infarct in CT prompting basal ganglia region, right side, be diagnosed as cerebrovascular arteries atherosis, treat symptom after month and take a turn for the better, left limb improving action, dizziness alleviates, sb.'s illness took a favorable turn leaves hospital, after with bilateral numbness of the fingers, insomnia forgetfulness.
Change and take the agent of a kind of atherosclerosis preparation granules of the present embodiment gained, adopt every day 2 times, each 4-6g, with warm boiled water, 30 days courses for the treatment of.After taking a course for the treatment of, numbness of the fingers, dizziness obviously alleviates; after taking two courses for the treatment of; limb activity functional rehabilitation is remarkable, and life can be taken care of oneself, after taking four courses for the treatment of substantially; the all diseases of patient disappear entirely; can normal activity, blood fat obviously declines, and hepatic and renal function is normal; consolidate a course for the treatment of, follow up a case by regular visits to after 1 year without recurrence.
embodiment 4a kind of atherosclerosis preparation, is prepared from (every part of 10g) primarily of following bulk drugs: Rhizoma Polygoni Cuspidati 11 parts, Cortex Lycii 11 parts, Flos Rosae Chinensis 10 parts, Flos Aglaiae Odoratae 10 parts, Fructus Adinae 12 parts, Herba Apocyni veneti 8 parts, Herba Syneilesis Aconitifoliae 10 parts, Radix Fici beecheyanae 12 parts, Herba Biondiae henryi 11 parts, Folium Camelliae sinensis 9 parts, Radix Codonopsis lanceolatae 13 parts, Radix cynanchi wilfordii 12 parts, Radix Flemingiae Philippinensis 9 parts, Herba mesonae chinensis 12 parts.
A kind of preparation method of atherosclerosis preparation powder is:
(1) get Radix Codonopsis lanceolatae and clean section, add water together with Flos Aglaiae Odoratae with Oryza glutinosa with boiling, when Oryza glutinosa boils to half ripe, Guan Huo, pulls Radix Codonopsis lanceolatae and Flos Aglaiae Odoratae out, and removing Oryza glutinosa, is stained with wine and dries;
(2) get Herba Syneilesis Aconitifoliae, Radix Fici beecheyanae and Herba Biondiae henryi yellow wine and soak 20 minutes, take out, be placed in Steam by water bath in bamboo drawer saturating, take out, dry in the air cool, section or cutting, be placed in frying pan, and moderate heat is fried to surperficial yellowish-brown, takes out, dries in the air cool;
(3) get Folium Camelliae sinensis and add decocting in water, little fire continues after boiling to boil 10 minutes, crosses and filters Folium Camelliae sinensis, collects filtrate, Radix cynanchi wilfordii and Radix Flemingiae Philippinensis is cleaned, and boils and exhausts to water, take out, dry with filtrate;
(4) together with Rhizoma Polygoni Cuspidati, Cortex Lycii, Flos Rosae Chinensis, Fructus Adinae, Herba Apocyni veneti and Herba mesonae chinensis and step (1) (2) (3) made crude drug, decocting in water is added, decoct three times, each amount of water is 7 times of boiled crude drug quality, big fire is boiled rear little fire and is boiled 31 minutes, filter, merge three gained filtrates;
(5) step (4) made filtrate concentrated, dry, pulverize 160 mesh sieves and become fine powder, add cane sugar powder mixing, sterilizing, obtains powder.
Model case: xxx, man, 68 years old.Main suit: suffer from hypertension and cerebral infarction 5 years, medication treatment always, but nearly two months, sensation recurrent dizziness, uncomfortable in chest, companion's facial numbness, walk unstable, Progressive symmetric erythrokeratodermia increases the weight of 6 days, examination in hospital, color ultrasound shows two bilateral common carotid artery many places Mottling formation, tongue is partially fat, dark red, yellow and greasy fur, stringy and thready pulse, is diagnosed as carotid arterial atherosclerosis.
Take a kind of atherosclerosis preparation of the present embodiment gained powder, adopt every day 2 times, each 4-6g, with warm boiled water, 30 days courses for the treatment of.After taking a course for the treatment of, patient is dizzy, uncomfortable in chest to alleviate, after taking three courses for the treatment of, patient facial region is numb, weak basic the elimination, after taking four courses for the treatment of, without malaise symptoms of feeling cold of lower limb, lower limb function recovers substantially, check, color ultrasound display media thickness and plaque area obviously reduce, and adhere to taking half a year, patient body is in good condition, follows up a case by regular visits to and do not recur after 1 year.
embodiment 5a kind of atherosclerosis preparation, is prepared from (every part of 10g) primarily of following bulk drugs: Rhizoma Polygoni Cuspidati 10 parts, Cortex Lycii 9.5 parts, Flos Rosae Chinensis 9 parts, Flos Aglaiae Odoratae 8.5 parts, Fructus Adinae 11 parts, Herba Apocyni veneti 6.5 parts, Herba Syneilesis Aconitifoliae 8.5 parts, Radix Fici beecheyanae 11 parts, Herba Biondiae henryi 9.5 parts, Folium Camelliae sinensis 8 parts, Radix Codonopsis lanceolatae 11.5 parts, Radix cynanchi wilfordii 10 parts, Radix Flemingiae Philippinensis 8 parts, Herba mesonae chinensis 10.5 parts.
A kind of preparation method of atherosclerosis preparation decoction is:
(1) get Radix Codonopsis lanceolatae and clean section, add water together with Flos Aglaiae Odoratae with Oryza glutinosa with boiling, when Oryza glutinosa boils to half ripe, Guan Huo, pulls Radix Codonopsis lanceolatae and Flos Aglaiae Odoratae out, and removing Oryza glutinosa, is stained with wine and dries;
(2) get Herba Syneilesis Aconitifoliae, Radix Fici beecheyanae and Herba Biondiae henryi yellow wine and soak 20 minutes, take out, be placed in Steam by water bath in bamboo drawer saturating, take out, dry in the air cool, section or cutting, be placed in frying pan, and moderate heat is fried to surperficial yellowish-brown, takes out, dries in the air cool;
(3) get Folium Camelliae sinensis and add decocting in water, little fire continues after boiling to boil 10 minutes, crosses and filters Folium Camelliae sinensis, collects filtrate, Radix cynanchi wilfordii and Radix Flemingiae Philippinensis is cleaned, and boils and exhausts to water, take out, dry with filtrate;
(4) together with Rhizoma Polygoni Cuspidati, Cortex Lycii, Flos Rosae Chinensis, Fructus Adinae and Herba mesonae chinensis and step (1) (2) (3) made crude drug, decocting in water is added, amount of water is 6 times of boiled crude drug quality, big fire is boiled rear little fire and is boiled 31 minutes, and filter, filtering residue adds water and boils, close fire and add Herba Apocyni veneti in first 10 minutes, filter, merge twice gained filtrate, be condensed into 1/2 of original volume, sterilizing, obtains decoction.
test example 1the clinical practice of a kind of atherosclerosis preparation (embodiment 5) of gained of the present invention:
In October ,-2014 in February, 2013, filter out 228 routine atherosclerotics in 4 hospital's Vasculocardiology Deparment outpatient services and in-patient department, wherein women 98 example, male 130 example, age 50-75 year, the mean age (60.4 ± 3.1) year, course of disease 1-6.Main clinic symptoms has that headache, dizziness, tinnitus, forgetful, cranial tinnitus, agitation, insomnia, paraesthesia, face are numb, chest pain, the soreness of waist, uncomfortable in chest etc.Carotid arterial atherosclerosis in various degree is all had with Mottling formation through color Doppler ultrasonography.
Patient is divided into two groups at random, experimental group 128 example and matched group 100 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference (
p> 0.05), there is comparability.Experimental group takes products obtained therefrom of the present invention, and take every day twice (warm), each 350m1-500m1(adjusts to some extent depending on concrete condition), 30 days courses for the treatment of, treat 6 courses for the treatment of continuously.Matched group takes other medicine as conventional medication such as compound gastrodia elata honey cyclohexanol peptide sheet, Dragon groundnut, tablets for promoting coronary circulation).Treatments period carries out Continuous Observation to two groups of patients, the appearance of record clinical symptoms and untoward reaction and situation of change.
Curative effect situation criterion: effective: tunica media of artery recovers normal substantially or speckle disappears; Effective: speckle quantity reduces or area reduces 0.02cm
2and more than, or tremulous pulse media thickness reduce 1/3rd and more than; Invalid: area, the quantity of speckle and tunica media of artery thickness is all unchanged or increase.Total effective rate=(effective+effectively)/total number of cases × 100%
Through treatment, experimental group patient, treats effective 57 examples (44.5%), and effective 65 examples (50.8%), experimental group total effective rate is 95.3%.In matched group, effective patient 27 example (27.0%), effective 44 examples (44.0%), matched group total effective rate is 71.0%, the treatment total effective rate of experimental group be significantly higher than matched group (
p< 0.05), two groups of differences have statistical significance.In therapeutic process, there is not untoward reaction phenomenon in experimental group patient, and matched group has 2 examples to occur myalgia, the slight nausea of 3 example, but every lab index is all normal.
The present invention selects the Rhizoma Polygoni Cuspidati having expelling wind and removing dampness, the Cortex Lycii of clearing away heat and cooling blood, the Flos Rosae Chinensis of loose poison detumescence, the Flos Aglaiae Odoratae of resolving depression alleviating distention in middle-JIAO, the Fructus Adinae of tonify deficiency kidney tonifying, the Herba Apocyni veneti of blood pressure lowering heart tonifying, the Herba Syneilesis Aconitifoliae of relaxing muscles and tendons to promote blood circulation, the Radix Fici beecheyanae of invigorating the spleen and benefiting QI, to regulate the flow of vital energy the Herba Biondiae henryi dispeled the wind, reduce phlegm the Folium Camelliae sinensis of diuresis, the Radix Codonopsis lanceolatae that evacuation of pus is eliminated the phlegm, the Radix cynanchi wilfordii of yin nourishing tonify deficiency, the Radix Flemingiae Philippinensis of wind-damp dispelling, the Herba mesonae chinensis of clearing away heat-damp and promoting diuresis, multiple medical material is collaborative plays effect, can play the effects such as promoting blood circulation by removing blood stasis, eliminating phlegm and calming wind, the spleen strengthening and damp drying.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. an atherosclerosis preparation, is characterized in that, is prepared from primarily of following bulk drugs, be mass parts: Rhizoma Polygoni Cuspidati 8-12, Cortex Lycii 6-13, Flos Rosae Chinensis 7-11, Flos Aglaiae Odoratae 5-12, Fructus Adinae 8-14, Herba Apocyni veneti 4-9, Herba Syneilesis Aconitifoliae 6-11, Radix Fici beecheyanae 9-13, Herba Biondiae henryi 7-12, Folium Camelliae sinensis 6-10, Radix Codonopsis lanceolatae 9-14, Radix cynanchi wilfordii 7-13, Radix Flemingiae Philippinensis 5-11, Herba mesonae chinensis 8-13.
2. a kind of atherosclerosis preparation as claimed in claim 1, it is characterized in that, Rhizoma Polygoni Cuspidati 9-11, Cortex Lycii 8-11, Flos Rosae Chinensis 8-10, Flos Aglaiae Odoratae 7-10, Fructus Adinae 10-12, Herba Apocyni veneti 5-8, Herba Syneilesis Aconitifoliae 7-10, Radix Fici beecheyanae 10-12, Herba Biondiae henryi 8-11, Folium Camelliae sinensis 7-9, Radix Codonopsis lanceolatae 10-13, Radix cynanchi wilfordii 8-12, Radix Flemingiae Philippinensis 7-9, Herba mesonae chinensis 9-12 is (preferred, Rhizoma Polygoni Cuspidati 10, Cortex Lycii 9.5, Flos Rosae Chinensis 9, Flos Aglaiae Odoratae 8.5, Fructus Adinae 11, Herba Apocyni veneti 6.5, Herba Syneilesis Aconitifoliae 8.5, Radix Fici beecheyanae 11, Herba Biondiae henryi 9.5, Folium Camelliae sinensis 8, Radix Codonopsis lanceolatae 11.5, Radix cynanchi wilfordii 10, Radix Flemingiae Philippinensis 8, Herba mesonae chinensis 10.5).
3. the preparation method of the decoction of a kind of atherosclerosis preparation as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Radix Codonopsis lanceolatae and clean section, add water together with Flos Aglaiae Odoratae with Oryza glutinosa with boiling, when Oryza glutinosa boils to half ripe, Guan Huo, pulls Radix Codonopsis lanceolatae and Flos Aglaiae Odoratae out, and removing Oryza glutinosa, is stained with wine and dries;
(2) get Herba Syneilesis Aconitifoliae, Radix Fici beecheyanae and Herba Biondiae henryi yellow wine and soak 20 minutes, take out, be placed in Steam by water bath in bamboo drawer saturating, take out, dry in the air cool, section or cutting, be placed in frying pan, and moderate heat is fried to surperficial yellowish-brown, takes out, dries in the air cool;
(3) get Folium Camelliae sinensis and add decocting in water, little fire continues after boiling to boil 10 minutes, crosses and filters Folium Camelliae sinensis, collects filtrate, Radix cynanchi wilfordii and Radix Flemingiae Philippinensis is cleaned, and boils and exhausts to water, take out, dry with filtrate;
(4) together with Rhizoma Polygoni Cuspidati, Cortex Lycii, Flos Rosae Chinensis, Fructus Adinae and Herba mesonae chinensis and step (1) (2) (3) made crude drug, decocting in water is added, amount of water is 6 times of boiled crude drug quality, big fire is boiled rear little fire and is boiled, and filter, filtering residue adds water and boils, close fire and add Herba Apocyni veneti in first 10 minutes, filter, merge twice gained filtrate, be condensed into 1/2 of original volume, sterilizing, obtains decoction.
4. the preparation method of a kind of atherosclerosis preparation decoction as claimed in claim 3, is characterized in that, step (4) big fire is boiled rear little fire and boiled 28-34 minute (preferred, little fire boils 30-32 minute; Be more preferably, little fire boils 31 minutes).
5. the preparation method of the soft extract of a kind of atherosclerosis preparation as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Radix Codonopsis lanceolatae and clean section, add water together with Flos Aglaiae Odoratae with Oryza glutinosa with boiling, when Oryza glutinosa boils to half ripe, Guan Huo, pulls Radix Codonopsis lanceolatae and Flos Aglaiae Odoratae out, and removing Oryza glutinosa, is stained with wine and dries;
(2) get Herba Syneilesis Aconitifoliae, Radix Fici beecheyanae and Herba Biondiae henryi yellow wine and soak 20 minutes, take out, be placed in Steam by water bath in bamboo drawer saturating, take out, dry in the air cool, section or cutting, be placed in frying pan, and moderate heat is fried to surperficial yellowish-brown, takes out, dries in the air cool;
(3) get Folium Camelliae sinensis and add decocting in water, little fire continues after boiling to boil 10 minutes, crosses and filters Folium Camelliae sinensis, collects filtrate, Radix cynanchi wilfordii and Radix Flemingiae Philippinensis is cleaned, and boils and exhausts to water, take out, dry with filtrate;
(4) Rhizoma Polygoni Cuspidati, Cortex Lycii, Fructus Adinae and Herba mesonae chinensis and step (1) (2) made crude drug are added decocting in water together with step (3) made Radix Flemingiae Philippinensis, decoct twice, each amount of water is 6 times of boiled crude drug quality, big fire is boiled rear little fire and is boiled 28-34 minute (preferred, little fire boils 30-32 minute; Be more preferably, little fire boils 31 minutes), filter, merge twice gained filtrate, be condensed into 1/2 of original volume;
(5) Flos Rosae Chinensis, Herba Apocyni veneti were pulverized 300 mesh sieves together with step (3) made Radix cynanchi wilfordii, and joined in step (4) made concentrated solution, with vinegar and starch, be brewed into thick paste, obtain soft extract.
6. the preparation method of a kind of atherosclerosis preparation soft extract as claimed in claim 5, is characterized in that, the relative density of step (5) thick paste is that 1.26-1.32(is preferred, and the relative density of thick paste is 1.28-1.30; Be more preferably, the relative density of thick paste is 1.29).
7. the preparation method of the granule of a kind of atherosclerosis preparation as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Radix Codonopsis lanceolatae and clean section, add water together with Flos Aglaiae Odoratae with Oryza glutinosa with boiling, when Oryza glutinosa boils to half ripe, Guan Huo, pulls Radix Codonopsis lanceolatae and Flos Aglaiae Odoratae out, and removing Oryza glutinosa, is stained with wine and dries;
(2) get Herba Syneilesis Aconitifoliae, Radix Fici beecheyanae and Herba Biondiae henryi yellow wine and soak 20 minutes, take out, be placed in Steam by water bath in bamboo drawer saturating, take out, dry in the air cool, section or cutting, be placed in frying pan, and moderate heat is fried to surperficial yellowish-brown, takes out, dries in the air cool;
(3) get Folium Camelliae sinensis and add decocting in water, little fire continues after boiling to boil 10 minutes, crosses and filters Folium Camelliae sinensis, collects filtrate, Radix cynanchi wilfordii and Radix Flemingiae Philippinensis is cleaned, and boils and exhausts to water, take out, dry with filtrate;
(4) together with Rhizoma Polygoni Cuspidati, Cortex Lycii, Flos Rosae Chinensis, Fructus Adinae, Herba Apocyni veneti and Herba mesonae chinensis and step (1) (2) (3) made crude drug, add decocting in water, decoct three times, big fire is boiled rear little fire and is boiled 28-34 minute (preferred, little fire boils 30-32 minute; Be more preferably, little fire boils 31 minutes), filter, merge three gained filtrates;
(5) step (4) made filtrate is concentrated, dry, pulverize into fine powder, add adjuvant, make granule of uniform size, sterilizing, obtain granule.
8. the preparation method of a kind of atherosclerosis preparation granules as claimed in claim 7 agent, it is characterized in that, step (4) decocts three times, and the 6-8 that each amount of water is boiled crude drug quality is (preferred, each amount of water is 7 times of boiled crude drug quality) doubly.
9. the preparation method of the powder of a kind of atherosclerosis preparation as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Radix Codonopsis lanceolatae and clean section, add water together with Flos Aglaiae Odoratae with Oryza glutinosa with boiling, when Oryza glutinosa boils to half ripe, Guan Huo, pulls Radix Codonopsis lanceolatae and Flos Aglaiae Odoratae out, and removing Oryza glutinosa, is stained with wine and dries;
(2) get Herba Syneilesis Aconitifoliae, Radix Fici beecheyanae and Herba Biondiae henryi yellow wine and soak 20 minutes, take out, be placed in Steam by water bath in bamboo drawer saturating, take out, dry in the air cool, section or cutting, be placed in frying pan, and moderate heat is fried to surperficial yellowish-brown, takes out, dries in the air cool;
(3) get Folium Camelliae sinensis and add decocting in water, little fire continues after boiling to boil 10 minutes, crosses and filters Folium Camelliae sinensis, collects filtrate, Radix cynanchi wilfordii and Radix Flemingiae Philippinensis is cleaned, and boils and exhausts to water, take out, dry with filtrate;
(4) together with Rhizoma Polygoni Cuspidati, Cortex Lycii, Flos Rosae Chinensis, Fructus Adinae, Herba Apocyni veneti and Herba mesonae chinensis and step (1) (2) (3) made crude drug, decocting in water is added, decoct three times, each amount of water is 7 times of boiled crude drug quality, big fire is boiled rear little fire and is boiled 28-34 minute (preferred, little fire boils 30-32 minute; Be more preferably, little fire boils 31 minutes), filter, merge three gained filtrates;
(5) step (4) made filtrate concentrated, dry, pulverize into fine powder, add cane sugar powder mixing, sterilizing, obtains powder.
10. the preparation method of a kind of atherosclerosis preparation powder as claimed in claim 9, is characterized in that, step (5) was pulverized 140-180 mesh sieve and (preferably, pulverized 150-170 mesh sieve; Be more preferably, pulverized 160 mesh sieves).
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109350643A (en) * | 2018-11-29 | 2019-02-19 | 北京大学 | The medical usage of the anti-ischemia apoplexy of Aglaia odorata extract |
| KR102355586B1 (en) * | 2021-05-07 | 2022-01-25 | 동의대학교 산학협력단 | Composition comprising syneilesis aconitifolia (bunge) maxim extract for preventing or treating brain neuronal disease |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103623341A (en) * | 2013-11-06 | 2014-03-12 | 秦先吉 | Drug for treating hypertension and cardiovascular and cerebrovascular diseases caused by hypertension |
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2015
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103623341A (en) * | 2013-11-06 | 2014-03-12 | 秦先吉 | Drug for treating hypertension and cardiovascular and cerebrovascular diseases caused by hypertension |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109350643A (en) * | 2018-11-29 | 2019-02-19 | 北京大学 | The medical usage of the anti-ischemia apoplexy of Aglaia odorata extract |
| KR102355586B1 (en) * | 2021-05-07 | 2022-01-25 | 동의대학교 산학협력단 | Composition comprising syneilesis aconitifolia (bunge) maxim extract for preventing or treating brain neuronal disease |
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