CN107789552A - A kind of medicine for treating hepatitis B and preparation method thereof - Google Patents

Abstract

The invention discloses a kind of medicine for treating hepatitis B and preparation method thereof, the medicine is mainly prepared by Common Sage Herb, oldenlandia diffusa, the red sage root, giant knotweed, smilax, rhizoma alismatis, stringy stonecrop, selfheal, Radix Isatidis, oriental wormwood, Sculellaria barbata, Chinese lobelia, hypericum japonicum, chrysanthemum indicum, rhizoma imperatae and rheum officinale.The medicine has the effect of blood circulation promoting and dispersing pathogen accumulation.Available for treating hepatitis B patient.Good effect, and Small side effects.

Description

A kind of medicine for treating hepatitis B and preparation method thereof

Technical field

The present invention relates to a kind of medicine for treating hepatitis B and preparation method thereof, belong to the field of medicine technology.

Background technology

Virus B hepatitis is by hepatitis B（HBV）It is caused, based on liver inflammatory lesion, and more devices can be caused A kind of disease of official's infringement.Hepatitis B is widely current in countries in the world, and main infringement children and person between twenty and fifty, small number of patients can be converted into Hepatic sclerosis or liver cancer.Therefore, it is the widest as the worldwide disease of serious threat human health, and China's current popular A kind of general, harmfulness most serious disease.Virus B hepatitis can fall ill without certain epizootic modeling throughout the year, but more Category distributes.The hepatitis B incidence of disease is in the trend substantially increased in recent years.

Chronic hepatitis B (abbreviation hepatitis B) refers to hepatitis B test positive, and the course of disease exceedes half a year or date of the onset not Clearly and clinic has chronic hepatitis shower.Clinical manifestation is the symptoms such as weak, sitophobia, nausea, abdominal distension, hepatalgia.Liver Greatly, quality is medium hardness, there is light tenderness.State of an illness severe one can be with chronic liver disease face, spider angioma, liver palms, splenomegaly, liver function Energy can exception or persistent anomaly.Slight, moderate and severe are divided into according to clinical manifestation.The traditional Chinese medical science thinks, chronic hepatitis B it is more because Acute hepatitis b is lost and controlled, or malpractice, with the passing of time delay forms, and treatment is taken in based on righting, and with eliminating evil, Major Clinical table It is now：Right flank secret anguish, receives poor abdominal distension, lip and tongue dryness, thirst and liking drink, and urine color is yellow, feverishness in palms and soles, hectic fever night sweat, dizzy weary Power, insomnia and dreamful sleep, two xerophtalmias, lassitude in loin and legs, abdominal distension receive difference, palpitation and short breath, spontaneous sweating, tired lazy speech, lusterless complexion, Dry is not thirsty, principle of reatment：Qi-blood tonifying, nourishing yin for softening liver, dim complexion, scaly dry skin is coarse, and the subcutaneous visible red silk of head is red In detail, liver palms, spider angioma, subcutaneous hemorrhage point, nosebleed, body are become thin, vena epigastrica anger, mass in abdomen.Principle of reatment：Grow Filling liver kidney, dispersing stagnated hepatoqi, qi and activate blood circulation, stagnation resolvation softening hard masses, qi-blood tonifying, nourishing yin for softening liver.Still lacked at present for chronic hepatitis B The effective medicine of few generally recognized as safe.

The content of the invention

It is an object of the present invention to provide a kind of medicine for treating hepatitis B and preparation method thereof.The medicine can have There is the effect of blood circulation promoting and dispersing pathogen accumulation, clearing heat and detoxicating.Available for treating hepatitis B patient.Good effect, and Small side effects.

In order to solve the above technical problems, the present invention is realized using following technical scheme：A kind of medicine for treating hepatitis B, Calculate by weight, mainly by Common Sage Herb 25-30 parts, oldenlandia diffusa 25-35 parts, red sage root 25-30 parts, giant knotweed 30-35 parts, soil Poria cocos 20-25 parts, rhizoma alismatis 15-20 parts, stringy stonecrop 15-20 parts, selfheal 15-20 parts, Radix Isatidis 20-25 parts, oriental wormwood 20-25 Part, Sculellaria barbata 20-25 parts, Chinese lobelia 20-25 parts, hypericum japonicum 25-30 parts, chrysanthemum indicum 20-25 parts, rhizoma imperatae 20-25 parts and big Yellow 5-10 parts are prepared.

In the medicine of foregoing treatment hepatitis B, calculate in parts by weight, mainly by Common Sage Herb 26-29 parts, long-noded pit viper Tongue grass 28-32 parts, red sage root 26-29 parts, giant knotweed 31-34 parts, smilax 21-24 parts, rhizoma alismatis 16-19 parts, stringy stonecrop 16-19 parts, Selfheal 16-19 parts, Radix Isatidis 21-24 parts, oriental wormwood 21-24 parts, Sculellaria barbata 21-24 parts, Chinese lobelia 21-24 parts, hypericum japonicum 26- 29 parts, chrysanthemum indicum 21-24 parts, rhizoma imperatae 21-24 parts and rheum officinale 6-9 parts are prepared.

In the medicine of foregoing treatment hepatitis B, calculate in parts by weight, mainly by 27.5 parts of Common Sage Herb, oldenlandia 30 parts of grass, 27.5 parts of the red sage root, 32.5 parts of giant knotweed, 22.5 parts of smilax, 17.5 parts of rhizoma alismatis, 17.5 parts of stringy stonecrop, selfheal 17.5 Part, 22.5 parts of Radix Isatidis, 22.5 parts of oriental wormwood, 22.5 parts of Sculellaria barbata, 22.5 parts of Chinese lobelia, 27.5 parts of hypericum japonicum, chrysanthemum indicum 22.5 7.5 parts of part, 22.5 parts of rhizoma imperatae and rheum officinale are prepared.

A kind of preparation method of the medicine of foregoing treatment hepatitis B, takes said medicine, is carried out with conventional pharmaceutical adjuvants Auxiliary material is combined or be not added with, traditional drug formulations are made.

In the preparation method of the medicine of foregoing treatment hepatitis B, the pharmaceutical preparation is oral formulations.

In the preparation method of the medicine of foregoing treatment hepatitis B, the oral formulations be decoction, tablet, capsule, Granule, pill or decoction.

Described decoction, it is to prepare as follows in the preparation method of the medicine of foregoing treatment hepatitis B：Take Medicinal material is stated, adds the 8-10 times of water measured immersion 10-15 minute, first big fire decocts 10-15min, is further continued for decocting 15- with small fire 25min, decoct 3 times, filtering, filtrate, concentration, produce.

In the preparation method of the medicine of foregoing treatment hepatitis B, described tablet：It is to prepare as follows：Take Medicinal material is stated, is extracted 2 times with the alcohol reflux of 6 times of amounts 70%, 1 hour every time, extract solution filtering, filtrate recycling ethanol was simultaneously condensed into Relative density is 1.20-1.25 medicinal extract, medicinal extract and the starch of medicinal extract amount 20% and the microcrystalline cellulose of medicinal extract amount 10% at 50-60 DEG C Element mixes, and tabletting, film coating, produces.

In the preparation method of the medicine of foregoing treatment hepatitis B, described capsule；It is to prepare as follows：Take Above-mentioned medicinal material, add the 8-10 times of water measured immersion 10-15 minute, first big fire decocts 10-15min, is further continued for decocting 15- with small fire 25min, decoct 3 times, filtering, merging filtrate, when filtrate is condensed into 50-60 DEG C relative density be 1.20-1.25 medicinal extract, medicinal extract Mix with the starch of medicinal extract amount 30% and the magnesium stearate of medicinal extract amount 0.7%, with 60% alcohol granulation, dry, pulverize, fill glue Capsule, produce.

In the preparation method of the medicine of foregoing treatment hepatitis B, described granule；It is to prepare as follows：Take Above-mentioned medicinal material, add the 8-10 times of water measured immersion 10-15 minute, first big fire decocts 10-15min, is further continued for decocting 15- with small fire 25min, decoct 3 times, filtering, merging filtrate, when filtrate is condensed into 50-60 DEG C relative density be 1.15-1.20 medicinal extract, medicinal extract With the starch of medicinal extract amount 20% and the dextrine powder mixing granulation of medicinal extract amount 20%, dry, produce.

Medicine of the present invention is mainly by Common Sage Herb, oldenlandia diffusa, the red sage root, giant knotweed, smilax, rhizoma alismatis, stringy stonecrop, summer Withered grass, Radix Isatidis, oriental wormwood, Sculellaria barbata, Chinese lobelia, hypericum japonicum, chrysanthemum indicum, rhizoma imperatae and rheum officinale are prepared.Wherein, lichee Grass, Salvia plebeia R. Br., there is heat-clearing, detoxify, cool blood, the effect of diuresis.Available for abscess of throat, bronchus Inflammation, nephritic dropsy, carbuncle swells；Control mastitis, hemorrhoid gall, bleeding outside.Oldenlandia diffusa（Scientific name：Hedyotis diffusa）For It is annual to hang down loosely draft, it is its patent medicine bitter, light, it is cold in nature.Primary efficacy is clearing heat and detoxicating, medicinal powder for relieving pain knot, promoting urination and removing dampness.You Shanzhi Treat all kinds inflammation.The red sage root, Chinese medicine name.For labiate red sage root Salvia miltiorrhiza Bge. dry root and Rhizome.Nature and flavor：Bitter, it is slightly cold.Channel tropism：The thoughts of returning home, Liver Channel.It is inducing meastruation to relieve menalgia with promoting blood circulation, relieving restlessness that clears away heart-fire, cool blood to disappear carbuncle it Effect.For chest impediment and cardialgia, gastral cavity abdomen hypochondriac pain, the accumulation of lump in the abdomen lump in the abdomen, hot numbness pain, dysphoria and insomnia, irregular menstruation, dysmenorrhoea Amenorrhea, sore Swelling and pain.Giant knotweed, it is polygonaceae plant giant knotweed Polygonum cuspidatum Sieb.et Zucc. dry rhizome and root.Have Removing dampness through diuresis and removing jaundice, clearing heat and detoxicating, blood stasis removing analgesic, it is relieving cough and reducing sputum the effect of.For jaundice with damp-heat pathogen, stranguria with turbid discharge, under band, arthralgia pain due to rheumatism, carbuncle Swollen sore, scald, Amenorrhea, abdominal mass, instep beat damage, cough with lung heat.Smilax, Chinese medicine name.For liliaceous plant light leaf greenbrier The dry rhizome of chinaroot greenbrier, it is sweet, light, it is mild-natured.Have removing toxic substances, dehumidify, it is easing joint movement the effect of, be mainly used in caused by syphilis and mercury poisoning Limbs contraction, arthralgia and myalgia；Damp and hot stranguria with turbid discharge, with, carbuncle swells, scrofula, mange.Rhizoma alismatis（Scientific name：Alisma plantago- aquatica Linn. ）It is used as medicine, nature and flavor：It is sweet, tremble with fear.Channel tropism：Enter kidney, bladder warp.Effect：Li Shui, excreting dampness, expel the heat-evil.Control urine not Profit, oedema turgor, vomiting, rush down dysentery, phlegm and retained fluid, tinea pedis, gonorrhoea, hematuria.Stringy stonecrop, Chinese medicine name.For crassulaceae plants stringy stonecrop Dry herb.It is sweet, light, it is cool.There is the effect of removing dampness through diuresis and removing jaundice, clearing heat and detoxicating.It is usually used in jaundice with damp-heat pathogen, difficult urination, carbuncle swells sore. Selfheal（Scientific name：Prunella vulgaris L）,【The property of medicine】It is pungent, bitter, tremble with fear.Return liver, gallbladder channel.【Effect】Clearing heat-fire, it is bright Mesh, mass dissipating and swelling eliminating.Radix Isatidis, Chinese medicine name.It is a kind of Chinese medicine.Hardship, tremble with fear.With clearing heat and detoxicating, the effect of cool blood relieving sore-throat.It is conventional It is malicious when warm epidemic disease, pharyngalgia of generating heat, febrile virulent maculae, mumps, scarlet fever, major part pestilence, erysipelas, carbuncle swells.Oriental wormwood, ArtemisiacapillarisThunb, meridian distribution of property and flavor：It is bitter, pungent, it is slightly cold.Returns spleen, stomach, liver, gallbladder channel.Oriental wormwood clearing heat and promoting diuresis；Move back It is yellow.Cure mainly：Jaundice, difficult urination, wet sore itch, infectious jaundice type hepatitis etc..Pharmaceutical research has cholagogic, protects liver function Can, antipyretic, anti-inflammatory, reducing blood lipid, it is depressured, the effect such as coronary dilatation.Sculellaria barbata（Scientific name：Scutellaria barbata D. Don）, Nature and flavor：It is pungent, put down.Major function：There is the effect of clearing heat and detoxicating, promoting blood circulation and removing blood stasis, swelling and pain relieving, anticancer；Appendicitis curing, hepatitis, stomach Bitterly, early liver cancer, lung cancer, cervix cancer, mastitis etc.；The diseases such as the treatment of pain furuncle, treating swelling and pain by traumatic injury are controlled in external application.Chinese lobelia（Scientific name： Lobelia chinensis Lour.）, have clearing heat and detoxicating, inducing diuresis to remove edema effect, control venomous snake bite, cirrhotic ascites, late period blood Fluke disease ascites, appendicitis effect etc..Hypericum japonicum is the herb of Garcinia maingayii hypericum japonicum.【Nature and flavor】：Sweet, slight bitter, is slightly cold. 【Channel tropism】：Return liver, the spleen channel.【Function is with curing mainly】：It is clearing heat and detoxicating, removing dampness through diuresis and removing jaundice, scattered stasis detumescence.For jaundice with damp-heat pathogen, acute appendicitis, mesh Red swelling and pain, heat toxin sore swells；Closely have for acute, chronic hepatitis, early-phase hepatocirrhosis, hepatalgia, appendicitis, mastitis, pulmonary abscess. Chrysanthemum indicum（Scientific name：Dendranthema indicum）For composite family herbaceos perennial, chrysanthemum indicum cold nature, tool evacuation wind Heat, subdhing swelling and detoxicating.The diseases such as furunculosis carbuncle swells, abscess of throat, wind-fire red eye, dizziness of having a headache can be treated.Rhizoma imperatae, Chinese medicine name.For Grass cogongrass Imperata cylindrica Beauv.var. major（ Nees）C.E.Hubb. dry rhizome. Nature and flavor：It is sweet, tremble with fear.Channel tropism：Return lung, stomach, bladder warp.Effect：Cooling blood and hemostasis, reducing fever and causing diuresis.Cure mainly：Spitted blood for blood-head, bleeding from five sense organs or subcutaneous tissue, Hematuria, pyreticosis polydipsia, cough with lung heat, gastropyretic vomiting, jaundice with damp-heat pathogen, oedema oliguria, puckery pain of heat gonorrhea.Rheum officinale, Rheum Palmatum L.【Nature and flavor and channel tropism】Hardship, tremble with fear.Returns spleen, stomach, large intestine, liver, pericardium channel.【Function is with curing mainly】Heat and toxic materials clearing away, heat-clearing Purging intense heat, removing pattogenic heat from the blood and toxic material from the body, dispelling stasis of blood and stimulating the menstrual flow, removing dampness through diuresis and removing jaundice.Stagnated constipation for real heat, blood-head tells nosebleed, hot eyes pharynx swelling, carbuncle swells furunculosis, Abdominalgia with intestinal abscess, blood stasis closed, postpartum stasis, traumatic injury, damp-heat dysentery, jaundice, stranguria, oedema；Externally treating burns and scalds.Wine Rheum officinale is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.For hot eyes pharynx swelling, gingivitis.Prepared RADIX ET RHIZOMA RHEI, which rushes down, exerts oneself to delay, purging intense heat and detonicating.For fiery poison sore Ulcer.Charred RADIX ET RHIZOMA RHEI cooling blood and removing stasis stops blooding.There is stasis of blood haemorrhage for blood-head.

Treat example：

Lee XX, 40 years old, is diagnosed as hepatitis B, often feels weak, is short of physical strength, anasarca, take medicine of the present invention（Press It is prepared by embodiment）After 1 week, the state of mind is clearly better, and oedema is alleviated, and continues after taking 3 weeks, the state of mind and muscle power are equal Recover, oedema disappears.

XX is opened, 36 years old, is diagnosed as hepatitis B, poor appetite, nausea often occurs, takes medicine of the present invention（By implementation It is prepared by example）After 3 weeks, appetite recovers normal, is no longer sick in the stomach.

King XX, 49 years old, is diagnosed as hepatitis B, and easily fatigue, abdominal discomfort, abdominal distension, takes medicine of the present invention（By reality Example is applied to be prepared）After 1 week, the state of mind is clearly better, and continues after taking 3 weeks, and abdominal discomfort closes abdominal distension sense and disappeared.

Poplar XX, 49 years old, is diagnosed as hepatitis B, often feels weak, is short of physical strength, anasarca, take medicine of the present invention Thing（Prepared by embodiment）After 1 week, the state of mind is clearly better, oedema alleviate, continue after taking 3 weeks, the state of mind and Muscle power is recovered, and oedema disappears.

Compared with prior art, medicine is made using above-mentioned raw materials in the present invention, and each component raw material has collaboration work(well Can, all medicines share, play altogether blood circulation promoting and dispersing pathogen accumulation and it is clearing heat and detoxicating the effect of.Available for treating hepatitis B patient.Good effect, and secondary work With small.

Invention is further described with reference to embodiment, but is not intended as the foundation limited the present invention.

Embodiment：

Embodiment 1.

Formula：Common Sage Herb 27.5g, oldenlandia diffusa 30g, red sage root 27.5g, giant knotweed 32.5g, smilax 22.5g, rhizoma alismatis 17.5g, Stringy stonecrop 17.5g, selfheal 17.5g, Radix Isatidis 22.5g, oriental wormwood 22.5g, Sculellaria barbata 22.5g, Chinese lobelia 22.5g, hypericum japonicum 27.5g, chrysanthemum indicum 22.5g, rhizoma imperatae 22.5g and rheum officinale 7.5g.

Technique：Above-mentioned medicinal material is taken, adds the 8-10 times of water measured immersion 10-15 minute, first big fire decocts 10-15min, is further continued for 15-25min is decocted with small fire, is decocted 3 times, filtering, filtrate, concentration, produces decoction.

Usage and dosage：Orally, it is daily 2-3 times, each daily 100-200ml.

Embodiment 2.

Formula:Common Sage Herb 29g, oldenlandia diffusa 32g, red sage root 29g, giant knotweed 34g, smilax 24g, rhizoma alismatis 19g, stringy stonecrop 19g, Selfheal 19g, Radix Isatidis 24g, oriental wormwood 24g, Sculellaria barbata 24g, Chinese lobelia 24g, hypericum japonicum 29g, chrysanthemum indicum 24g, rhizoma imperatae 24g With rheum officinale 9g.

Technique takes above-mentioned medicinal material, is extracted 2 times with the alcohol reflux of 6 times of amounts 70%, 1 hour every time, extract solution filtered, filtrate The medicinal extract that relative density is 1.20-1.25 when reclaiming ethanol and being condensed into 50-60 DEG C, starch and leaching of the medicinal extract with medicinal extract amount 20% The microcrystalline cellulose of cream amount 10% mixes, and tabletting, film coating, produces tablet.

Specification：Every 0.5g.

Usage and dosage：3 times a day, 2 tablets once, orally.

Embodiment 3.

Formula:Common Sage Herb 26g, oldenlandia diffusa 28g, red sage root 26g, giant knotweed 31g, smilax 21g, rhizoma alismatis 16g, stringy stonecrop 16g, Selfheal 16g, Radix Isatidis 21g, oriental wormwood 21g, Sculellaria barbata 21g, Chinese lobelia 21g, hypericum japonicum 26g, chrysanthemum indicum 21g, rhizoma imperatae 21g With rheum officinale 6g.

Technique:Above-mentioned medicinal material is taken, adds the water of 8 times of amounts to soak 10 minutes, first big fire decocts 10min, is further continued for being decocted with small fire 15min is boiled, is decocted 3 times, filtering, merging filtrate, relative density is 1.20-1.25 medicinal extract when filtrate is condensed into 50-60 DEG C, is soaked Cream mixes with the starch of medicinal extract amount 30% and the magnesium stearate of medicinal extract amount 0.7%, with 60% alcohol granulation, dry, pulverize, and fills Capsule, produce granule

Specification：Every bag of 5g.

Usage and dosage：3 times a day, each 5-10g, orally.

Claims (10)

1. A kind of 1. medicine for treating hepatitis B, it is characterised in that：Calculate by weight, mainly by Common Sage Herb 25-30 parts, white flower HERBA HEDYOTIS DIFFUSAE 25-35 parts, red sage root 25-30 parts, giant knotweed 30-35 parts, smilax 20-25 parts, rhizoma alismatis 15-20 parts, stringy stonecrop 15-20 Part, selfheal 15-20 parts, Radix Isatidis 20-25 parts, oriental wormwood 20-25 parts, Sculellaria barbata 20-25 parts, Chinese lobelia 20-25 parts, hypericum japonicum 25-30 parts, chrysanthemum indicum 20-25 parts, rhizoma imperatae 20-25 parts and rheum officinale 5-10 parts are prepared.
2. 2. the medicine for the treatment of hepatitis B as claimed in claim 1, it is characterised in that：Calculate in parts by weight, mainly by litchi The careless 26-29 parts of branch, oldenlandia diffusa 28-32 parts, red sage root 26-29 parts, giant knotweed 31-34 parts, smilax 21-24 parts, rhizoma alismatis 16-19 Part, stringy stonecrop 16-19 parts, selfheal 16-19 parts, Radix Isatidis 21-24 parts, oriental wormwood 21-24 parts, Sculellaria barbata 21-24 parts, Chinese lobelia 21-24 parts, hypericum japonicum 26-29 parts, chrysanthemum indicum 21-24 parts, rhizoma imperatae 21-24 parts and rheum officinale 6-9 parts are prepared.
3. 3. the medicine for the treatment of hepatitis B as claimed in claim 2, it is characterised in that：Calculate in parts by weight, mainly by litchi 27.5 parts of branch grass, 30 parts of oldenlandia diffusa, 27.5 parts of the red sage root, 32.5 parts of giant knotweed, 22.5 parts of smilax, 17.5 parts of rhizoma alismatis, vertical basin 17.5 parts of grass, 17.5 parts of selfheal, 22.5 parts of Radix Isatidis, 22.5 parts of oriental wormwood, 22.5 parts of Sculellaria barbata, 22.5 parts of Chinese lobelia, Tian Ji 7.5 parts of yellow 27.5 parts, 22.5 parts of chrysanthemum indicum, 22.5 parts of rhizoma imperatae and rheum officinale are prepared.
4. A kind of 4. preparation method of the medicine for the treatment of hepatitis B as any one of claim 1-3, it is characterised in that： Said medicine is taken, with conventional pharmaceutical adjuvants or being not added with auxiliary material combination, traditional drug formulations are made.
5. 5. the preparation method of the medicine for the treatment of hepatitis B as claimed in claim 4, it is characterised in that：The pharmaceutical preparation is Oral formulations.
6. 6. the preparation method of the medicine for the treatment of hepatitis B as claimed in claim 5, it is characterised in that：The oral formulations are Decoction, tablet, capsule, granule, pill or decoction.
7. 7. the preparation method of the medicine for the treatment of hepatitis B as claimed in claim 6, it is characterised in that:Described decoction, it is Prepare as follows：Above-mentioned medicinal material is taken, adds the 8-10 times of water measured immersion 10-15 minute, first big fire decocts 10-15min, followed by It is continuous to decoct 15-25min with small fire, decoct 3 times, filtering, filtrate, concentration, produce.
8. 8. the preparation method of the medicine for the treatment of hepatitis B as claimed in claim 6, it is characterised in that:Described tablet：It is Prepare as follows：Above-mentioned medicinal material is taken, is extracted 2 times, 1 hour every time, extract solution filtering, filtered with the alcohol reflux of 6 times of amounts 70% Liquid reclaims ethanol and relative density is 1.20-1.25 medicinal extract when being condensed into 50-60 DEG C, the starch of medicinal extract and medicinal extract amount 20% and The microcrystalline cellulose of medicinal extract amount 10% mixes, and tabletting, film coating, produces.
9. 9. the preparation method of the medicine for the treatment of hepatitis B as claimed in claim 6, it is characterised in that:Described capsule； It is to prepare as follows：Above-mentioned medicinal material is taken, adds the 8-10 times of water measured immersion 10-15 minute, first big fire decocts 10-15min, then Continue to decoct 15-25min with small fire, decoct 3 times, filtering, merging filtrate, relative density is when filtrate is condensed into 50-60 DEG C 1.20-1.25 medicinal extract, medicinal extract mixes with the starch of medicinal extract amount 30% and the magnesium stearate of medicinal extract amount 0.7%, with 60% ethanol system Grain, dry, pulverize, and fills capsule, produces.
10. 10. the preparation method of the medicine for the treatment of hepatitis B as claimed in claim 6, it is characterised in that:Described granule； It is to prepare as follows：Above-mentioned medicinal material is taken, adds the 8-10 times of water measured immersion 10-15 minute, first big fire decocts 10-15min, then Continue to decoct 15-25min with small fire, decoct 3 times, filtering, merging filtrate, relative density is when filtrate is condensed into 50-60 DEG C 1.15-1.20 medicinal extract, medicinal extract and the starch of medicinal extract amount 20% and the dextrine powder mixing granulation of medicinal extract amount 20%, dry, produce.