CN1279933C - Chinese materia medica preparation for treating cough and preparation method - Google Patents
Chinese materia medica preparation for treating cough and preparation method Download PDFInfo
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- CN1279933C CN1279933C CN 200410081552 CN200410081552A CN1279933C CN 1279933 C CN1279933 C CN 1279933C CN 200410081552 CN200410081552 CN 200410081552 CN 200410081552 A CN200410081552 A CN 200410081552A CN 1279933 C CN1279933 C CN 1279933C
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Abstract
The present invention relates to a Chinese medicine preparation for treating cough and a preparation method thereof. The Chinese medicine preparation is prepared by the following medicine used as raw material: lysionotus pauciflorus, pilose gerbera herb, platycodon root and liquorice. The preparation method comprises the following steps: a water boil alcohol sinking extraction method or a hydrous alcohol extraction method is adopted; through extraction operation, required powdered extract which is an extract product is obtained; the powdered extract is adopted to be prepared into capsules (including gastric solubility capsules and enteric solubility capsules), granules (including sugar-containing granules and non-sugar granules), tablets (film coated tablets and sugar-coated tablets), and buccal tablets. The Chinese medicine preparation has the functions for relieving cough, relieving asthma, moistening lung and eliminating phlegm. The Chinese medicine preparation can be used for treating cough and asthma caused by a common cold. The Chinese medicine preparation can also be used for treating acute and chronic tracheitis, and pneumonia cough.
Description
Technical field: the present invention relates to cough-relieving, relieving asthma, lung moistening, expectorant Chinese medicine preparation, particularly a kind of Chinese medicine preparation for the treatment of cough and preparation method thereof.
Background technology: in the medicine of existing treatment cough, Western medicine mostly is depressor of nerve centre, takes for a long time to have addiction mostly; Chinese medicine mostly is crude drug decocting Stewed Dish and directly makes, and dose is big, and effective site is indeterminate, directly influences drug effect.
Summary of the invention: the object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of cough and preparation method thereof, reach cough, asthma that treatment is caused by flu, also treat the purpose of acute and chronic tracheitis and pneumonia cough.
Formation of the present invention: it is to be made by the material medicine of following consumption: Lysionotus carnosus Hemsl. (Lysionotus pauciflorus Maxim.) 1000～1500g (doing) or 5000～7500g (aquatic foods), Herba Gerberae Piloselloidis 300～600g (doing) or 1500～3000g (aquatic foods), Radix Platycodonis 100～400g, Radix Glycyrrhizae 100～300g.
Preparation technology (1): with Lysionotus carnosus Hemsl. (Lysionotus pauciflorus Maxim.), Herba Gerberae Piloselloidis, Radix Platycodonis, after Radix Glycyrrhizae is pulverized, water decocts 3 times, each water consumption is 6～12 times, decocting time is 2 hours the 1st time, the 2nd, 3 times each 1 hour, filter, merging filtrate, be concentrated into relative density and be 1.08～1.10 fluid extract, add ethanol and make and contain the alcohol amount and reach 60%, left standstill 48 hours, filter, it is 1.12～1.18 extractum that filtrate recycling ethanol gets relative density, uses water saturated n-butanol extraction, and butanol extraction liquid concentrates, spray drying or vacuum drying get dry extract, make capsule (comprising gastric solubility capsule and enteric solubility capsule) with this dry extract, granule (sugar-containing type and non-sugared type), tablet (Film coated tablets and coated tablet) and buccal tablets.
Preparation technology (2): with Lysionotus carnosus Hemsl. (Lysionotus pauciflorus Maxim.), Herba Gerberae Piloselloidis, Radix Platycodonis, after Radix Glycyrrhizae powder is broken into coarse powder, with 70%～85% alcohol reflux 3 times, each alcohol adding amount is 6～10 times, decocting time is 2 hours the 1st time, the 2nd, 3 times each 1 hour, filter, merging filtrate, reclaiming solvent, to get relative density be 1.12～1.18 fluid extract, uses water saturated n-butanol extraction, butanol extraction liquid concentrates, spray drying or vacuum drying get dry extract, make capsule (comprising gastric solubility capsule and enteric solubility capsule) with this dry extract, granule (sugar-containing type and non-sugared type), tablet (Film coated tablets, coated tablet) and buccal tablets.
Compared with the prior art, the present invention have cough-relieving, relieving asthma, lung moistening, expectorant effect.Adopt the modern pharmaceutical technology, discard the dross and select the essential, effective site is clear and definite, and taking dose is little, makes multiple peroral dosage form, is convenient to take and carry.
The specific embodiment:
Embodiment 1: get Lysionotus carnosus Hemsl. (Lysionotus pauciflorus Maxim.) 1000g (doing) or 5000g (aquatic foods), Herba Gerberae Piloselloidis 300g (doing) or 1500g (aquatic foods), Radix Platycodonis 100g, Radix Glycyrrhizae 100g.
Preparation technology (1): with Lysionotus carnosus Hemsl. (Lysionotus pauciflorus Maxim.), Herba Gerberae Piloselloidis, Radix Platycodonis, after Radix Glycyrrhizae is pulverized, water decocts 3 times, each water consumption is 6～12 times, decocting time is 2 hours the 1st time, the 2nd, 3 times each 1 hour, filter, merging filtrate, be concentrated into relative density and be 1.08～1.10 fluid extract, add ethanol and make and contain the alcohol amount and reach 60%, left standstill 48 hours, filter, it is 1.12～1.18 extractum that filtrate recycling ethanol gets relative density, uses water saturated n-butanol extraction, and butanol extraction liquid concentrates, spray drying or vacuum drying get dry extract, make capsule (comprising gastric solubility capsule and enteric solubility capsule) with this dry extract, granule (sugar-containing type and non-sugared type), tablet (Film coated tablets and coated tablet) and buccal tablets.Act as cough-relieving, relieving asthma, lung moistening, eliminate the phlegm, can be used as cough, asthma that treatment is caused by flu, also treat the medicine of acute and chronic tracheitis and pneumonia cough.
Preparation technology (2): with Lysionotus carnosus Hemsl. (Lysionotus pauciflorus Maxim.), Herba Gerberae Piloselloidis, Radix Platycodonis, after Radix Glycyrrhizae powder is broken into coarse powder, with 70%～85% alcohol reflux 3 times, each alcohol adding amount is 6～10 times, decocting time is 2 hours the 1st time, the 2nd, 3 times each 1 hour, filter, merging filtrate, reclaiming solvent, to get relative density be 1.12～1.18 fluid extract, uses water saturated n-butanol extraction, butanol extraction liquid concentrates, spray drying or vacuum drying get dry extract, make capsule (comprising gastric solubility capsule and enteric solubility capsule) with this dry extract, granule (sugar-containing type and non-sugared type), tablet (Film coated tablets, coated tablet) and buccal tablets.Act as cough-relieving, relievining asthma sheet.Act as cough-relieving, relieving asthma, lung moistening, eliminate the phlegm, can be used as cough, asthma that treatment is caused by flu, also treat the medicine of acute and chronic tracheitis and pneumonia cough.
Embodiment 2: get Lysionotus carnosus Hemsl. (Lysionotus pauciflorus Maxim.) 1500g (doing) or 7500g (aquatic foods), Herba Gerberae Piloselloidis 600g (doing) or 3000g (aquatic foods), Radix Platycodonis 400g, Radix Glycyrrhizae 300g.
Preparation technology (1): with Lysionotus carnosus Hemsl. (Lysionotus pauciflorus Maxim.), Herba Gerberae Piloselloidis, Radix Platycodonis, after Radix Glycyrrhizae is pulverized, water decocts 3 times, each water consumption is 6～12 times, decocting time is 2 hours the 1st time, the 2nd, 3 times each 1 hour, filter, merging filtrate, be concentrated into relative density and be 1.08～1.10 fluid extract, add ethanol and make and contain the alcohol amount and reach 60%, left standstill 48 hours, filter, it is 1.12～1.18 extractum that filtrate recycling ethanol gets relative density, uses water saturated n-butanol extraction, and butanol extraction liquid concentrates, spray drying or vacuum drying get dry extract, make capsule (comprising gastric solubility capsule and enteric solubility capsule) with this dry extract, granule (sugar-containing type and non-sugared type), tablet (Film coated tablets and coated tablet) and buccal tablets.Act as cough-relieving, relieving asthma, lung moistening, eliminate the phlegm, can be used as cough, asthma that treatment is caused by flu, also treat the medicine of acute and chronic tracheitis and pneumonia cough.
Preparation technology (2): with Lysionotus carnosus Hemsl. (Lysionotus pauciflorus Maxim.), Herba Gerberae Piloselloidis, Radix Platycodonis, after Radix Glycyrrhizae powder is broken into coarse powder, with 70%～85% alcohol reflux 3 times, each alcohol adding amount is 6～10 times, decocting time is 2 hours the 1st time, the 2nd, 3 times each 1 hour, filter, merging filtrate, reclaiming solvent, to get relative density be 1.12～1.18 fluid extract, uses water saturated n-butanol extraction, butanol extraction liquid concentrates, spray drying or vacuum drying get dry extract, make capsule (comprising gastric solubility capsule and enteric solubility capsule) with this dry extract, granule (sugar-containing type and non-sugared type), tablet (Film coated tablets, coated tablet) and buccal tablets.Act as cough-relieving, relievining asthma sheet.Act as cough-relieving, relieving asthma, lung moistening, eliminate the phlegm, can be used as cough, asthma that treatment is caused by flu, also treat the medicine of acute and chronic tracheitis and pneumonia cough.
Claims (2)
1. Chinese medicine preparation for the treatment of cough, it is characterized in that it is made up of effective ingredient and/or adjuvant, wherein make raw materials of effective components and consist of dried Lysionotus carnosus Hemsl. (Lysionotus pauciflorus Maxim.) 1000～1500g or bright Lysionotus carnosus Hemsl. (Lysionotus pauciflorus Maxim.) 5000～7500g, dried Herba Gerberae Piloselloidis 300～600g or bright Herba Gerberae Piloselloidis 1500～3000g, Radix Platycodonis 100～400g, Radix Glycyrrhizae 100～300g.
2. a kind of preparation method for the treatment of the Chinese medicine preparation of cough as claimed in claim 1, it is characterized in that: preparation technology (1): Lysionotus carnosus Hemsl. (Lysionotus pauciflorus Maxim.), Herba Gerberae Piloselloidis, Radix Platycodonis, after Radix Glycyrrhizae is pulverized, water decocts 3 times, each water consumption is 6～12 times, decocting time is 2 hours the 1st time, the 2nd, 3 times each 1 hour, filter, merging filtrate is concentrated into relative density and is 1.08～1.10 fluid extract, adding ethanol makes and contains the alcohol amount and reach 60%, left standstill 48 hours, and filtered, it is 1.12～1.18 extractum that filtrate recycling ethanol gets relative density, use water saturated n-butanol extraction, butanol extraction liquid concentrates, and spray drying or vacuum drying get dry extract, make capsule with this dry extract, granule, tablet and buccal tablets;
Preparation technology (2): after Lysionotus carnosus Hemsl. (Lysionotus pauciflorus Maxim.), Herba Gerberae Piloselloidis, Radix Platycodonis, Radix Glycyrrhizae powder be broken into coarse powder, with 70%～85% alcohol reflux 3 times, each alcohol adding amount is 6～10 times, decocting time is 2 hours the 1st time, the 2nd, 3 times each 1 hour, filter, merging filtrate, reclaiming solvent, to get relative density be 1.12～1.18 fluid extract, use water saturated n-butanol extraction, and butanol extraction liquid is concentrated, spray drying or vacuum drying get dry extract, make capsule, granule, tablet and buccal tablets with this dry extract.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410081552 CN1279933C (en) | 2004-12-16 | 2004-12-16 | Chinese materia medica preparation for treating cough and preparation method |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410081552 CN1279933C (en) | 2004-12-16 | 2004-12-16 | Chinese materia medica preparation for treating cough and preparation method |
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| Publication Number | Publication Date |
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| CN1660268A CN1660268A (en) | 2005-08-31 |
| CN1279933C true CN1279933C (en) | 2006-10-18 |
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| CN 200410081552 Expired - Fee Related CN1279933C (en) | 2004-12-16 | 2004-12-16 | Chinese materia medica preparation for treating cough and preparation method |
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| CN103053749B (en) * | 2012-12-25 | 2014-05-07 | 蓝秀香 | Health tea containing bulbuphyllum incomspicuum |
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Granted publication date: 20061018 Termination date: 20111216 |