CN102085249A - Weishuning capsule - Google Patents

Abstract

The invention discloses a Weishuning capsule which is prepared according to the following steps: properly extracting licorice, cuttlebone, white peony root, bighead atractylodes rhizome, corydalis tuber and dangshen which are used as raw medicines; adding auxiliary materials; uniformly mixing; and encapsulating the mixture into a capsule shell to obtain the Weishuning capsule. The medicine disclosed by the invention has the functions of invigorating qi and strengthening the spleen and relieving hyperacidity and relieving pain, and is more convenient to take and carry; and by removing impurities by a proper extraction method, the contents of effective components can be improved, the dose can be reduced, and toxic side effects possibly caused by the impurities can be reduced.

Description

A kind of stomach oxazepan capsule

Technical field

The present invention relates to the pharmaceutical preparations technology field, especially a kind of stomach oxazepan capsule.

Background technology

Stomach oxazepan granule is the prescribed preparation that records in one one of Pharmacopoeia of People's Republic of China version in 2005, has the effect of air making-up and spleen enlivening, relieving gastric hyperacidity to alleviate stomachache.With 595 parts in Radix Glycyrrhizae, 595 parts of Endoconcha Sepiaes, 464 parts of the Radix Paeoniae Albas, 310 parts of the Rhizoma Atractylodis Macrocephalaes, 310 parts of Rhizoma Corydalis, Radix Codonopsis is raw material for 119 parts, makes granule after each raw medicinal material decoction is extracted.Because granule is being taken and easy to carry all not too convenient, thereby has limited its clinical practice to a certain extent.And, in its traditional extracting method, after the decocting in water extraction, only remove precipitation by leaving standstill, impurity content is higher, is unfavorable for the enrichment of active component and the performance of therapeutic effect.

Summary of the invention

Purpose of the present invention just provides a kind of stomach oxazepan capsule, this medicine has the effect of air making-up and spleen enlivening, relieving gastric hyperacidity to alleviate stomachache, take and carry all more convenient, and remove impurity by suitable extracting method, effectively the content of forming improves, also can reduce dose, and reduce the toxic and side effects that impurity may cause.

In order to realize the foregoing invention purpose, the technical solution used in the present invention is as follows:

A kind of stomach oxazepan capsule, with following amount amount part proportion raw material medicine:

595 parts in Radix Glycyrrhizae, 595 parts of Endoconcha Sepiaes, 464 parts of the Radix Paeoniae Albas, 310 parts of the Rhizoma Atractylodis Macrocephalaes, 310 parts of Rhizoma Corydalis, 119 parts of Radix Codonopsis,

Make according to the method that comprises the steps:

(1), extracts crude drug: each crude drug of getting described proportioning, add water 8-12 times weight, decoct and extract 3-4 time, merge decoction liquor, be concentrated into this 1.05-1.10 of relative density, add ethanol to containing the alcohol amount, left standstill 8-24 hour, filter for 60-80%, get supernatant and reclaim ethanol, concentrate then, be dried to dry extract, standby;

(2), make capsule: the dry extract that step (1) is made is broken into fine powder, and adding starch or dextrin are an amount of, and mix homogeneously is granulated, and divides in the capsule shells of packing into, promptly.

Compared with prior art, the invention has the beneficial effects as follows: medicine stomach oxazepan capsule of the present invention has the effect of air making-up and spleen enlivening, relieving gastric hyperacidity to alleviate stomachache, capsule make take and carry all more convenient; And by suitable extracting method and removal impurity, effectively the content of forming improves, and also can reduce dose, and reduces the toxic and side effects that impurity may cause.

The specific embodiment

The present invention is described in further detail below in conjunction with the specific embodiment.

Following each embodiment stomach oxazepan capsule all makes with following raw materials in weight portion medicine:

595 parts in Radix Glycyrrhizae, 595 parts of Endoconcha Sepiaes, 464 parts of the Radix Paeoniae Albas, 310 parts of the Rhizoma Atractylodis Macrocephalaes, 310 parts of Rhizoma Corydalis, 119 parts of Radix Codonopsis.

Embodiment 1

Present embodiment stomach oxazepan capsule makes according to the method that comprises the steps:

(1), extracts crude drug: get each crude drug of described proportioning, add 8 times of weight of water, decoct and extract 4 times, merge decoction liquor, be concentrated into relative density this 1.10, adding ethanol is 80% to containing the alcohol amount, standing over night is filtered, get supernatant and reclaim ethanol, concentrate then, be dried to dry extract, standby;

(2), make capsule: the dry extract that step (1) is made is broken into fine powder, and adding starch is an amount of, and mix homogeneously is granulated, and divides in the capsule shells of packing into, promptly.

Embodiment 2

Present embodiment stomach oxazepan capsule makes according to the method that comprises the steps:

(1), extracts crude drug: get each crude drug of described proportioning, add 10 times of weight of water, decoct and extract 4 times, merge decoction liquor, be concentrated into relative density this 1.05, adding ethanol is 70% to containing the alcohol amount, leaves standstill 24 hours, filters, get supernatant and reclaim ethanol, concentrate then, be dried to dry extract, standby;

(2), make capsule: the dry extract that step (1) is made is broken into fine powder, and adding starch is an amount of, and mix homogeneously is granulated, and divides in the capsule shells of packing into, promptly.

Embodiment 3

Present embodiment stomach oxazepan capsule makes according to the method that comprises the steps:

(1), extracts crude drug: get each crude drug of described proportioning, add 12 times of weight of water, decoct and extract 3 times, merge decoction liquor, be concentrated into relative density this 1.05, adding ethanol is 60% to containing the alcohol amount, leaves standstill 8 hours, filters, get supernatant and reclaim ethanol, concentrate then, be dried to dry extract, standby;

(2), make capsule: the dry extract that step (1) is made is broken into fine powder, and the adding dextrin is an amount of, and mix homogeneously is granulated, and divides in the capsule shells of packing into, promptly.

Claims (1)

1. stomach oxazepan capsule, with following amount amount part proportion raw material medicine:

595 parts in Radix Glycyrrhizae, 595 parts of Endoconcha Sepiaes, 464 parts of the Radix Paeoniae Albas, 310 parts of the Rhizoma Atractylodis Macrocephalaes, 310 parts of Rhizoma Corydalis, 119 parts of Radix Codonopsis,

Make according to the method that comprises the steps:

(1), extracts crude drug: each crude drug of getting described proportioning, add water 8-12 times weight, decoct and extract 3-4 time, merge decoction liquor, be concentrated into this 1.05-1.10 of relative density, add ethanol to containing the alcohol amount, left standstill 8-24 hour, filter for 60-80%, get supernatant and reclaim ethanol, concentrate then, be dried to dry extract, standby;

(2), make capsule: the dry extract that step (1) is made is broken into fine powder, and adding starch or dextrin are an amount of, and mix homogeneously is granulated, and divides in the capsule shells of packing into, promptly.