CN101670079A - Chinese medicament for treating chronic atrophic gastritis, preventing and treating gastric cancer - Google Patents
Chinese medicament for treating chronic atrophic gastritis, preventing and treating gastric cancer Download PDFInfo
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- CN101670079A CN101670079A CN200810119841A CN200810119841A CN101670079A CN 101670079 A CN101670079 A CN 101670079A CN 200810119841 A CN200810119841 A CN 200810119841A CN 200810119841 A CN200810119841 A CN 200810119841A CN 101670079 A CN101670079 A CN 101670079A
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Abstract
The invention discloses a Chinese medicament for treating chronic atrophic gastritis, preventing and treating gastric cancer, and a preparation method thereof. The effective component of the medicament is prepared from dozens of medicinal material, such as astragalus mongholicus, white peony root, ginseng, Chinese angelica, largetrifoliolious bugbane rhizome, yanhusuo, Chinese fever vine, common bletilla pseudobulb, rhizoma zingiberis preparata, cassia twig, villous amomum fruit, Chinese gall, liquorice root and the like through extraction. The unique medicinal active component in the medicament has the effects of warming middle-Jiao and notifying deficiency, regulating the function of the liver and spleen, and promoting vital energy and activating blood, and is used for treating gastral cavity cool and pain, flatulence, eructation, anorexia, cold intolerance, asthenia and other diseases caused by the chronic atrophic gastritis and chronic gastritis.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicine pharmacy, be specifically related to a kind of Chinese medicine for the treatment of chronic atrophic gastritis, preventing and treating gastric cancer.
Technical background
Influence digests, steals nutrition, impairs one's health, and only gastritis is on small scale, and its ultimate aim is to shake body to become cancer, rope people life! Atrophic gastritis belongs to the scope of precancerous lesion, and atrophic gastritis has the canceration possibility with severe intestinal gland metaplasia and atypical hyperplasia person.The canceration rate of atrophic gastritis is 6%-18.5%.80% does not have symptom, is some non-specific performances even small number of patients has symptom yet, as inappetence, full, abdominal discomfort etc. early, very easily by as peptic ulcer or other gastroenteropathys and out in the cold.The late period of atrophic gastritis all can occur intestinal epithelial metaplasia in various degree, general intestinal epithelial metaplasia is that small intestine epitheliumization is given birth to, and the danger of canceration is still little.If develop into big visible peristalsis visible intestinal peristalsis intestinal epithelial metaplasia, that just from canceration within sight.This moment is active if occur atypical hyperplasia again, and that is exactly the canceration signal.The early gastric cancer patient, China's gastric cancer mortality ranks first in the world, this is enough to explanation, gastropathy is quite serious in the harm of China, if gastropathy can not get treatment for a long time, will cause serious even the initiation canceration, gastric cancer generally betides all gastric mucosas of stomach ulcer, and these positions stimulate generation cancerations down.In addition, if suffered from gastropathy, not only influence work, life work and emotion and gastropathy also have heritability and infectiousness, are potential threats to household and offspring, therefore, gastropathy expert makes an appeal, if you the stomachache flatulence occurred, and the symptom of gastric acid, should watch out for gastropathy constantly and threaten your health, radical cure gastropathy is very urgent.
Summary of the invention:
The purpose of this invention is to provide a kind of Chinese medicine for the treatment of chronic atrophic gastritis, preventing and treating gastric cancer;
Another object of the present invention provides this preparation method of Chinese medicine;
Be achieved through the following technical solutions (part is unit of weight) order of the present invention:
1, prescription:
Radix Astragali 100-300 part Radix Paeoniae Alba 80-240 part Radix Ginseng 100-300 part
Radix Angelicae Sinensis 100-300 part Rhizoma Cimicifugae 80-240 part Rhizoma Corydalis 100-300 part
Fevervine 80-240 part Pseudobulbus Bletillae (Rhizoma Bletillae) 80-240 part Rhizoma Zingiberis Preparatum 50-150 part
Ramulus Cinnamomi 80-240 part Fructus Amomi 50-150 part Galla Chinensis 80-240 part
Radix Glycyrrhizae 50-150 part
Effective ingredient is preferably made by weight by following raw materials according:
200 parts of 160 parts of Radix Ginsengs of 200 portions of Radix Paeoniae Albas of the Radix Astragali
200 parts of 160 parts of Rhizoma Corydalis of 200 parts of Rhizoma Cimicifugaes of Radix Angelicae Sinensis
100 parts of 160 portions of Rhizoma Zingiberis Preparatums of 160 parts of Pseudobulbus Bletillae (Rhizoma Bletillae) of fevervine
160 parts of 100 parts of Galla Chinensiss of 160 parts of Fructus Amomis of Ramulus Cinnamomi
100 parts in Radix Glycyrrhizae
The active ingredient preparation method of Chinese medicine of the present invention can be that raw material is dry respectively, and levigation mixes.It also can be the conventional method preparation of adopting herbal pharmaceutical.These pharmacy conventional methods can be water extract-alcohol precipitation or ethanol extract from water precipitation, also have other extracting method in addition, specifically " pharmaceutics of Chinese drugs " published referring to Cao Chunlin chief editor's Shanghai science tech publishing house.
2, preparation technology:
(1) Radix Astragali, Radix Angelicae Sinensis, Ramulus Cinnamomi are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(2) Radix Paeoniae Alba, Radix Ginseng, Rhizoma Cimicifugae, Rhizoma Corydalis, fevervine, Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Zingiberis Preparatum, Fructus Amomi, Galla Chinensis, Radix Glycyrrhizae decoct with water secondary, each 2 hours, filter, merging filtrate, left standstill 48 hours, and got supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density;
(3) with step (1) gained clear paste and step (2) gained thick paste mixing, drying is ground into fine powder, makes granule, capsule and pill with pharmaceutically acceptable carrier.
Adopt above-mentioned prescription and preparation method thereof, the present invention has warming middle-Jiao and tonifying deficiency, regulating the liver and spleen, and the effect of promoting flow of QI and blood is used for the treatment of chronic atrophic gastritis, the cool pain of the caused gastral cavilty of chronic gastritis, flatulence, belch, poor appetite, fear of cold, unable disease such as grade.
By the following examples technical scheme of the present invention is described further.
The specific embodiment
Embodiment 1: the preparation technology of granule
1, prescription:
200 parts of 160 parts of Radix Ginsengs of 200 portions of Radix Paeoniae Albas of the Radix Astragali
200 parts of 160 parts of Rhizoma Corydalis of 200 parts of Rhizoma Cimicifugaes of Radix Angelicae Sinensis
100 parts of 160 portions of Rhizoma Zingiberis Preparatums of 160 parts of Pseudobulbus Bletillae (Rhizoma Bletillae) of fevervine
160 parts of 100 parts of Galla Chinensiss of 160 parts of Fructus Amomis of Ramulus Cinnamomi
100 parts in Radix Glycyrrhizae
2, preparation technology:
(1) Radix Astragali 200g, Radix Angelicae Sinensis 200g, Ramulus Cinnamomi 160g are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(2) Radix Paeoniae Alba 160g, Radix Ginseng 200g, Rhizoma Cimicifugae 160g, Rhizoma Corydalis 200g, fevervine 160g, Pseudobulbus Bletillae (Rhizoma Bletillae) 160g, Rhizoma Zingiberis Preparatum 100g, Fructus Amomi 100g, Galla Chinensis 160g, Radix Glycyrrhizae 100g decoct with water secondary, each 2 hours, filter, merging filtrate, left standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density;
(3) step (1) gained clear paste and step (2) gained thick paste are added dextrin 600g, lactose 400g, mixing, drying is ground into fine powder, with 75% ethanol wet granulation promptly.
Embodiment 2: the preparation technology of capsule
1, prescription:
200 parts of 160 parts of Radix Ginsengs of 200 portions of Radix Paeoniae Albas of the Radix Astragali
200 parts of 160 parts of Rhizoma Corydalis of 200 parts of Rhizoma Cimicifugaes of Radix Angelicae Sinensis
100 parts of 160 portions of Rhizoma Zingiberis Preparatums of 160 parts of Pseudobulbus Bletillae (Rhizoma Bletillae) of fevervine
160 parts of 100 parts of Galla Chinensiss of 160 parts of Fructus Amomis of Ramulus Cinnamomi
100 parts in Radix Glycyrrhizae
2, preparation technology:
(1) Radix Astragali 200g, Radix Angelicae Sinensis 200g, Ramulus Cinnamomi 160g are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(2) Radix Paeoniae Alba 160g, Radix Ginseng 200g, Rhizoma Cimicifugae 160g, Rhizoma Corydalis 200g, fevervine 160g, Pseudobulbus Bletillae (Rhizoma Bletillae) 160g, Rhizoma Zingiberis Preparatum 100g, Fructus Amomi 100g, Galla Chinensis 160g, Radix Glycyrrhizae 100g decoct with water secondary, each 2 hours, filter, merging filtrate, left standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density;
(3) step (1) gained clear paste and step (2) gained thick paste are merged add dextrin 800g mixing, drying is ground into fine powder, sieve, mixing, in the capsulae vacuus of packing into promptly.
Embodiment 3: the preparation technology of pill
1, prescription:
200 parts of 160 parts of Radix Ginsengs of 200 portions of Radix Paeoniae Albas of the Radix Astragali
200 parts of 160 parts of Rhizoma Corydalis of 200 parts of Rhizoma Cimicifugaes of Radix Angelicae Sinensis
100 parts of 160 portions of Rhizoma Zingiberis Preparatums of 160 parts of Pseudobulbus Bletillae (Rhizoma Bletillae) of fevervine
160 parts of 100 parts of Galla Chinensiss of 160 parts of Fructus Amomis of Ramulus Cinnamomi
100 parts in Radix Glycyrrhizae
2, preparation technology:
(1) Radix Astragali 200g, Radix Angelicae Sinensis 200g, Ramulus Cinnamomi 160g are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(2) Radix Paeoniae Alba 160g, Radix Ginseng 200g, Rhizoma Cimicifugae 160g, Rhizoma Corydalis 200g, fevervine 160g, Pseudobulbus Bletillae (Rhizoma Bletillae) 160g, Rhizoma Zingiberis Preparatum 100g, Fructus Amomi 100g, Galla Chinensis 160g, Radix Glycyrrhizae 100g decoct with water secondary, each 2 hours, filter, merging filtrate, left standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density;
(3) step (1) gained clear paste and step (2) gained thick paste are merged adding dextrin 400g mixing, drying is ground into fine powder, adds refined honey 100g, closes to stick together, and makes big honeyed pills.
Claims (5)
1, a kind of Chinese medicine for the treatment of chronic atrophic gastritis, preventing and treating gastric cancer is characterized in that being made up of active ingredient and/or pharmaceutically acceptable carrier, and wherein said active ingredient is made by following raw materials according:
Radix Astragali 100-300 part Radix Paeoniae Alba 80-240 part Radix Ginseng 100-300 part
Radix Angelicae Sinensis 100-300 part Rhizoma Cimicifugae 80-240 part Rhizoma Corydalis 100-300 part
Fevervine 80-240 part Pseudobulbus Bletillae (Rhizoma Bletillae) 80-240 part Rhizoma Zingiberis Preparatum 50-150 part
Ramulus Cinnamomi 80-240 part Fructus Amomi 50-150 part Galla Chinensis 80-240 part
Radix Glycyrrhizae 50-150 part.
2, a kind of Chinese medicine for the treatment of chronic atrophic gastritis, preventing and treating gastric cancer according to claim 1 is characterized in that wherein preparing the preferred following raw materials according of described active ingredient:
200 parts of 160 parts of Radix Ginsengs of 200 portions of Radix Paeoniae Albas of the Radix Astragali
200 parts of 160 parts of Rhizoma Corydalis of 200 parts of Rhizoma Cimicifugaes of Radix Angelicae Sinensis
100 parts of 160 portions of Rhizoma Zingiberis Preparatums of 160 parts of Pseudobulbus Bletillae (Rhizoma Bletillae) of fevervine
160 parts of 100 parts of Galla Chinensiss of 160 parts of Fructus Amomis of Ramulus Cinnamomi
100 parts in Radix Glycyrrhizae.
3, according to the described a kind of Chinese medicine for the treatment of chronic atrophic gastritis, preventing and treating gastric cancer of claim 1-2, it is characterized in that adopting following method to make:
(1) Radix Astragali, Radix Angelicae Sinensis, Ramulus Cinnamomi are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(2) Radix Paeoniae Alba, Radix Ginseng, Rhizoma Cimicifugae, Rhizoma Corydalis, fevervine, Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Zingiberis Preparatum, Fructus Amomi, Galla Chinensis, Radix Glycyrrhizae decoct with water secondary, each 2 hours, filter, merging filtrate, left standstill 48 hours, and got supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density;
(3) with step (1) gained clear paste and step (2) gained thick paste mixing, drying is ground into fine powder, makes granule, capsule and pill with pharmaceutically acceptable carrier.
4, according to any one described a kind of Chinese medicine for the treatment of chronic atrophic gastritis, preventing and treating gastric cancer among the claim 1-3, it is characterized in that this Chinese medicine composition is an oral formulations.
5, according to the described a kind of Chinese medicine for the treatment of chronic atrophic gastritis, preventing and treating gastric cancer of claim 3-4, it is characterized in that this Chinese medicine composition can be made into granule, capsule, pill.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810119841A CN101670079A (en) | 2008-09-11 | 2008-09-11 | Chinese medicament for treating chronic atrophic gastritis, preventing and treating gastric cancer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810119841A CN101670079A (en) | 2008-09-11 | 2008-09-11 | Chinese medicament for treating chronic atrophic gastritis, preventing and treating gastric cancer |
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| Publication Number | Publication Date |
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| CN101670079A true CN101670079A (en) | 2010-03-17 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200810119841A Pending CN101670079A (en) | 2008-09-11 | 2008-09-11 | Chinese medicament for treating chronic atrophic gastritis, preventing and treating gastric cancer |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103055286A (en) * | 2012-12-27 | 2013-04-24 | 柳州市中医院 | A traditional Chinese medicine for treating chronic atrophic gastritis and a preparation method thereof |
| CN103169935A (en) * | 2013-03-21 | 2013-06-26 | 陈欣 | Medicated food preparation for treating atrophic gastritis and preparation method thereof |
-
2008
- 2008-09-11 CN CN200810119841A patent/CN101670079A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103055286A (en) * | 2012-12-27 | 2013-04-24 | 柳州市中医院 | A traditional Chinese medicine for treating chronic atrophic gastritis and a preparation method thereof |
| CN103055286B (en) * | 2012-12-27 | 2014-05-07 | 柳州市中医院 | Traditional Chinese medicine for treating chronic atrophic gastritis and preparation method thereof |
| CN103169935A (en) * | 2013-03-21 | 2013-06-26 | 陈欣 | Medicated food preparation for treating atrophic gastritis and preparation method thereof |
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Open date: 20100317 |