CN1272445C - 利用吸附剂纯化头孢菌素c肉汤的方法 - Google Patents

利用吸附剂纯化头孢菌素c肉汤的方法 Download PDF

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Publication number
CN1272445C
CN1272445C CNB2004100015501A CN200410001550A CN1272445C CN 1272445 C CN1272445 C CN 1272445C CN B2004100015501 A CNB2004100015501 A CN B2004100015501A CN 200410001550 A CN200410001550 A CN 200410001550A CN 1272445 C CN1272445 C CN 1272445C
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China
Prior art keywords
cpc
aca
cephalosporin
amino
deacetylation
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Expired - Fee Related
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CNB2004100015501A
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English (en)
Chinese (zh)
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CN1517442A (zh
Inventor
金正优
申相圭
尹钟赞
尹仁均
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CKD Bio Corp
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CKD Bio Corp
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/06—Cephalosporin C; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01093—Glutaryl-7-aminocephalosporanic-acid acylase (3.5.1.93)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Seeds, Soups, And Other Foods (AREA)
  • Cephalosporin Compounds (AREA)
  • Soy Sauces And Products Related Thereto (AREA)
CNB2004100015501A 2003-01-15 2004-01-13 利用吸附剂纯化头孢菌素c肉汤的方法 Expired - Fee Related CN1272445C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2003-0002664A KR100479404B1 (ko) 2003-01-15 2003-01-15 흡착제를 이용한 세팔로스포린ｃ 배양액의 정제방법
KR2664/2003 2003-01-15

Publications (2)

Publication Number Publication Date
CN1517442A CN1517442A (zh) 2004-08-04
CN1272445C true CN1272445C (zh) 2006-08-30

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ID=34309343

Family Applications (1)

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CNB2004100015501A Expired - Fee Related CN1272445C (zh) 2003-01-15 2004-01-13 利用吸附剂纯化头孢菌素c肉汤的方法

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KR (1) KR100479404B1 (ko)
CN (1) CN1272445C (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102584561B (zh) * 2011-12-14 2014-12-24 伊犁川宁生物技术有限公司 一种回收酶法制备7-氨基头孢烷酸过程中产生的戊二酸副产物的方法
CN103374563B (zh) * 2012-04-13 2016-07-20 上海医药工业研究院 一种改良7-aca产生菌的方法

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Publication number Publication date
KR100479404B1 (ko) 2005-03-31
CN1517442A (zh) 2004-08-04
KR20040065092A (ko) 2004-07-21

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
CI01 Correction of invention patent gazette

Correction item: Inventor

Correct: Yin Renjun

False: Yin Renjun

Number: 31

Volume: 20

CI02 Correction of invention patent application

Correction item: Inventor

Correct: Yin Renjun

False: Yin Renjun

Number: 31

Page: The title page

Volume: 20

C14 Grant of patent or utility model
GR01 Patent grant
C19 Lapse of patent right due to non-payment of the annual fee
CF01 Termination of patent right due to non-payment of annual fee