CN1267138C - 补肾益寿泡腾片及其制备方法 - Google Patents

补肾益寿泡腾片及其制备方法 Download PDF

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CN1267138C
CN1267138C CNB2004100466188A CN200410046618A CN1267138C CN 1267138 C CN1267138 C CN 1267138C CN B2004100466188 A CNB2004100466188 A CN B2004100466188A CN 200410046618 A CN200410046618 A CN 200410046618A CN 1267138 C CN1267138 C CN 1267138C
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radix
effervescent tablet
fine powder
ganoderma
margarita
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CN1596968A (zh
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李叶华
江岩
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Kamp Pharmaceuticals Co Ltd
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YIXIAOTANG (HUNAN) PHARM Manufacturing CO Ltd
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Abstract

一种补肾益寿泡腾片，它是一种主要成分为中药红参、珍珠、灵芝、制何首乌、枸杞子、淫羊藿、丹参、甘草、黄精的泡腾片。制备方法是：主要成分的重量百分比用量为：红参、甘草各2-5%，珍珠0.1-1%，灵芝、丹参、黄精各5-15%，制何首乌、枸杞子各15-25%，淫羊藿20-35%；红参、珍珠粉碎成细粉，其余灵芝等七味加水煎煮二次，合并煎液，滤过，取上清液浓缩成稠膏，加适量淀粉，混匀，低温干燥，粉碎成细粉，与红参、珍珠粉剂混匀，分成两组，加入适量的填充剂、矫味剂后，分别加入柠檬酸、苏打适量，分别制成颗粒，干燥，整粒后混合均匀，加入硬脂酸镁适量，混合均匀，压制成片，即得。补肾益寿泡腾片优点是药物中含矫味剂、泡腾剂，在水中能迅速崩解，同时味道可口，便于服用。

Description

补肾益寿泡腾片及其制备方法
技术领域：
本发明涉及一种中药片剂及其制作工艺方法，尤其涉及补肾益寿泡腾片及其制备方法。
背景技术：
泡腾片作为一种药物剂型，根据我国药品管理的相关法规，改变剂型作为新药研究管理。含有与本专利处方药物基本相同的补肾益寿制剂已有胶囊剂，已列入国家药品部颁标准，但是国家标准中并未具体公开各处方药物的具体配比含量。
现有胶囊剂的工艺技术特点是将处方量药材部分粉碎后，剩余部分煎煮，滤液浓缩成稠膏，加入适当的辅料混合，制粒、干燥，即得胶囊剂。
现有的补肾益寿胶囊存在防潮性能较差及服用时胶囊易粘食道等缺点。
发明内容：
本发明的目的是提供一种具有优良补肾益寿功能的能迅速崩解，且味道可口的补肾益寿片剂及其制备方法，克服现有技术的上述弊端，提高产品的质量和疗效，更好地满足医疗的需要。
本发明的技术解决方案是一种补肾益寿泡腾片，其特征在于它是主要成分为中药红参、珍珠、灵芝、制何首乌、枸杞子、淫羊藿、丹参、甘草、黄精的泡腾片。
补肾益寿泡腾片的制备方法是：
(1)主要组成成分及其重量百分比用量如下：
红参、甘草各2-5％，珍珠0.1-1％，灵芝、丹参、黄精各5-15％，制何首乌、枸杞子各15-25％，淫羊藿20-35％；
(2)将红参、珍珠粉碎成细粉，备用；
(3)将余下灵芝等七味加水煎煮二次，合并煎液，滤过，取上清液浓缩成稠膏，加适量淀粉，混匀，低温干燥，粉碎成细粉，备用；
(4)将(2)与(3)的细粉及适量的辅料混合均匀，分成两组，加入适量的填充剂、矫味剂后，分别加入柠檬酸、苏打适量，分别制成颗粒，干燥，整粒后，颗粒备用；
(5)将(4)所得两组颗粒混合，加入硬脂酸镁适量，混合均匀；
(6)将(5)所得颗粒压制成片，即得。
上述制备方法中，主要组成成分的最佳重量百分比为：红参、甘草各3.70％，珍珠0.13％，灵芝、丹参、黄精各9.25％，制何首乌、枸杞子各18.49％，淫羊藿27.74％。
具体实施方案：
本发明结合具体实施例进一步说明如下：
一种补肾益寿泡腾片，它是主要成分为红参、珍珠、灵芝、制何首乌、枸杞子、淫羊藿、丹参、甘草、黄精的泡腾片。
制备方法是：
(1)主要组成成分及其重量百分比用量如下：
红参、甘草各2-5％，珍珠0.1-1％，灵芝、丹参、黄精各5-15％，制何首乌、枸杞子各15-25％，淫羊藿20-35％；
以制备1000片补肾益寿泡腾片为例，取红参、甘草各3.70％，珍珠0.13％，灵芝、丹参、黄精各9.25％，制何首乌、枸杞子各18.49％，淫羊藿27.74％；
(2)将红参、珍珠粉碎成细粉，备用；
(3)将余下灵芝等七味加水煎煮二次，合并煎液，滤过，取上清液浓缩成稠膏，加适量淀粉，混匀，低温干燥，粉碎成细粉，备用；
(4)将(2)与(3)的细粉及适量的辅料混合均匀，分成两组，加入适量的填充剂、矫味剂后，分别加入柠檬酸、苏打各30g，分别制成颗粒，干燥，整粒后，颗粒备用；
(5)将(4)所得两组颗粒混合，加入颗粒总量1％的硬脂酸镁，混合均匀；
(6)将(5)所得颗粒压制成片，即得。
本发明的优点是：
本发明产品具有良好的补肾益寿效果，补肾益寿泡腾片是由药物与赋型剂、矫味剂、泡腾剂组成，在水中能迅速崩解，同时药物中加入了适当的矫味剂，味道可口，便于服用。

Claims (4)

1、一种补肾益寿泡腾片，其特征在于是由下述重量百分比的原料药制成的：红参、甘草各2-5％，珍珠0.1-1％，灵芝、丹参、黄精各5-15％，制何首乌、枸杞子各15-25％，淫羊藿20-35％。
2、一种补肾益寿泡腾片的制备方法，其特征在于：
(1)原料药重量百分比为：
红参、甘草各2-5％，珍珠0.1-1％，灵芝、丹参、黄精各5-15％，制何首乌、枸杞子各15-25％，淫羊藿20-35％；
(2)将红参、珍珠粉碎成细粉，备用；
(3)将余下灵芝等七味加水煎煮二次，合并煎液，滤过，取上清液浓缩成稠膏，加适量淀粉，混匀，低温干燥，粉碎成细粉，备用；
(4)将(2)与(3)的细粉及适量的辅料混合均匀，分成两组，加入适量的填充剂、矫味剂后，分别加入柠檬酸、苏打适量，分别制成颗粒，干燥，整粒后，颗粒备用；
(5)将(4)所得两组颗粒混合，加入硬脂酸镁适量，混合均匀；
(6)将(5)所得颗粒压制成片，即得。
3、根据权利要求1所述的补肾益寿泡腾片，其特征在于各原料药的重量百分比为：
红参、甘草各3.70％，珍珠0.13％，灵芝、丹参、黄精各9.25％，制何首乌、枸杞子各18.49％，淫羊藿27.74％。
4、如权利要求2所述的补肾益寿泡腾片制备方法，其特征在于，原料药重量百分比为：红参、甘草各3.70％，珍珠0.13％，灵芝、丹参、黄精各9.25％，制何首乌、枸杞子各18.49％，淫羊藿27.74％。
CNB2004100466188A 2004-07-30 2004-07-30 补肾益寿泡腾片及其制备方法 Expired - Fee Related CN1267138C (zh)

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