CN1264307B - 改善上胃肠道功能的方法 - Google Patents
改善上胃肠道功能的方法 Download PDFInfo
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- CN1264307B CN1264307B CN988073307A CN98807330A CN1264307B CN 1264307 B CN1264307 B CN 1264307B CN 988073307 A CN988073307 A CN 988073307A CN 98807330 A CN98807330 A CN 98807330A CN 1264307 B CN1264307 B CN 1264307B
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- igf
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- upper gastrointestinal
- peptide
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
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| US4675497P | 1997-05-16 | 1997-05-16 | |
| US60/046,754 | 1997-05-16 | ||
| GBGB9715481.9A GB9715481D0 (en) | 1997-07-23 | 1997-07-23 | Methods of enhancing functioning of the upper gastrointestinal tract |
| GB9715481.9 | 1997-07-23 | ||
| US09/059,504 | 1998-04-13 | ||
| US09/059,504 US6051557A (en) | 1997-05-16 | 1998-04-13 | Methods of enhancing functioning of the upper gastrointestinal tract |
| PCT/CA1998/000497 WO1998052600A1 (en) | 1997-05-16 | 1998-05-15 | Methods of enhancing functioning of the upper gastrointestinal tract |
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| CN1264307A CN1264307A (zh) | 2000-08-23 |
| CN1264307B true CN1264307B (zh) | 2013-10-30 |
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| CN988073307A Expired - Fee Related CN1264307B (zh) | 1997-05-16 | 1998-05-15 | 改善上胃肠道功能的方法 |
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| EP (1) | EP0981362B1 (enExample) |
| JP (2) | JP4699576B2 (enExample) |
| CN (1) | CN1264307B (enExample) |
| AT (1) | ATE253375T1 (enExample) |
| AU (1) | AU746633B2 (enExample) |
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| AU746633B2 (en) * | 1997-05-16 | 2002-05-02 | 1149336 Ontario Inc. | Methods of enhancing functioning of the upper gastrointestinal tract |
| GB9905416D0 (en) * | 1999-03-09 | 1999-05-05 | Allelix Biopharma | Small molecules having GLP-2 like activity |
| RU2164349C1 (ru) * | 1999-07-27 | 2001-03-20 | Нижегородская государственная медицинская академия | Способ определения стоматологического статуса |
| US20030040478A1 (en) * | 1999-12-08 | 2003-02-27 | Drucker Daniel J | Chemotherapy treatment |
| US7186683B2 (en) | 2000-09-18 | 2007-03-06 | Sanos Bioscience A/S | Use of GLP for the treatment, prevention, diagnosis, and prognosis of bone-related and nutrition-related disorders |
| US7371721B2 (en) | 2000-09-18 | 2008-05-13 | Sanos Bioscience A/S | Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes |
| ATE396738T1 (de) * | 2000-09-18 | 2008-06-15 | Sanos Bioscience As | Verwendung von glp-2-peptiden |
| US7411039B2 (en) | 2002-10-14 | 2008-08-12 | Novo Nordisk A/S | GLP-2 compounds, formulations, and uses thereof |
| EP1809318B1 (en) | 2004-11-01 | 2013-06-12 | NPS Pharmaceuticals, Inc. | Treatment of short bowel syndrome patients with colon-in-continuity |
| CN101171262B (zh) | 2005-05-04 | 2012-06-27 | 西兰制药公司 | 胰高血糖素样肽-2(glp-2)类似物 |
| NZ576260A (en) * | 2006-11-08 | 2012-04-27 | Zealand Pharma As | GLUCAGON-LIKE-PEPTIDE-2 (GLP-2) ANALOGUES comprising one of more substitutions as compared to h[Gly2]GLP-2 |
| WO2010042145A1 (en) * | 2008-09-19 | 2010-04-15 | Nektar Therapeutics | Polymer conjugates of glp-2-like peptides |
| EP2611825B1 (en) * | 2010-08-30 | 2015-09-02 | NPS Pharmaceuticals, Inc. | Solid phase synthesis of h(gly2)glp-2 |
| CN104540850B (zh) | 2012-05-03 | 2018-05-18 | 西兰制药公司 | 胰高血糖素样肽2(glp-2)类似物 |
| EP3299023A4 (en) * | 2015-05-21 | 2019-03-20 | Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences | OXYGEN ARM-TREATED MESENCHYMM STEM CELL AND ITS USE |
| CA3043151A1 (en) | 2016-12-09 | 2018-06-14 | Zealand Pharma A/S | Acylated glp-1/glp-2 dual agonists |
| EP4424362A3 (en) | 2017-06-16 | 2024-11-27 | Zealand Pharma A/S | Dosage regimes for the administration of glucagon-like-peptide-2 (glp-2) analogues |
| CN108273038B (zh) * | 2018-03-16 | 2019-03-19 | 中国人民解放军军事科学院军事医学研究院 | 防治肠型放射病的药物组合物 |
| CN110226566A (zh) * | 2019-07-12 | 2019-09-13 | 南京中医药大学 | 一种放射性口腔黏膜炎动物模型的造模方法 |
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| DK27885A (da) * | 1985-01-22 | 1986-07-23 | Novo Industri As | Fremstilling af peptider |
| US5990077A (en) * | 1995-04-14 | 1999-11-23 | 1149336 Ontario Inc. | Glucagon-like peptide-2 and its therapeutic use |
| CN1268640C (zh) * | 1996-04-12 | 2006-08-09 | 1149336安大略公司 | 胰高血糖素样肽－2的类似物 |
| EP1012186B1 (en) * | 1996-12-06 | 2002-07-17 | Amgen Inc., | Use of a kgf protein product(s) and a glp-2 protein product(s) for the preparation of a medicament |
| US5952301A (en) * | 1996-12-10 | 1999-09-14 | 1149336 Ontario Inc. | Compositions and methods for enhancing intestinal function |
| AU746633B2 (en) * | 1997-05-16 | 2002-05-02 | 1149336 Ontario Inc. | Methods of enhancing functioning of the upper gastrointestinal tract |
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1998
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- 1998-05-15 BR BR9808804-1A patent/BR9808804A/pt not_active Application Discontinuation
- 1998-05-15 EP EP98922546A patent/EP0981362B1/en not_active Expired - Lifetime
- 1998-05-15 MX MXPA99010523A patent/MXPA99010523A/es active IP Right Grant
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| AU746633B2 (en) | 2002-05-02 |
| WO1998052600A1 (en) | 1998-11-26 |
| WO1998052600A9 (en) | 2000-03-09 |
| CN1264307A (zh) | 2000-08-23 |
| HK1030160A1 (en) | 2001-04-27 |
| JP4699576B2 (ja) | 2011-06-15 |
| MXPA99010523A (es) | 2004-09-01 |
| CA2289652A1 (en) | 1998-11-26 |
| JP2009280598A (ja) | 2009-12-03 |
| AU7516398A (en) | 1998-12-11 |
| EP0981362A1 (en) | 2000-03-01 |
| JP2002502369A (ja) | 2002-01-22 |
| DK0981362T3 (da) | 2004-03-15 |
| PT981362E (pt) | 2004-03-31 |
| DE69819488T2 (de) | 2004-08-26 |
| EP0981362B1 (en) | 2003-11-05 |
| ATE253375T1 (de) | 2003-11-15 |
| BR9808804A (pt) | 2001-09-18 |
| CA2289652C (en) | 2012-02-28 |
| DE69819488D1 (de) | 2003-12-11 |
| ES2210756T3 (es) | 2004-07-01 |
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