JP4699576B2 - 胃腸管上部の機能を強化する方法 - Google Patents

胃腸管上部の機能を強化する方法 Download PDF

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Publication number
JP4699576B2
JP4699576B2 JP54974198A JP54974198A JP4699576B2 JP 4699576 B2 JP4699576 B2 JP 4699576B2 JP 54974198 A JP54974198 A JP 54974198A JP 54974198 A JP54974198 A JP 54974198A JP 4699576 B2 JP4699576 B2 JP 4699576B2
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JP
Japan
Prior art keywords
peptide
glp
gastrointestinal tract
analog
upper gastrointestinal
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Expired - Fee Related
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JP54974198A
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English (en)
Japanese (ja)
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JP2002502369A (ja
JP2002502369A5 (enExample
Inventor
ドラッカー,ダニエル,ジェイ.
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1149336
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1149336
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Publication date
Priority claimed from GBGB9715481.9A external-priority patent/GB9715481D0/en
Priority claimed from US09/059,504 external-priority patent/US6051557A/en
Application filed by 1149336 filed Critical 1149336
Publication of JP2002502369A publication Critical patent/JP2002502369A/ja
Publication of JP2002502369A5 publication Critical patent/JP2002502369A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
JP54974198A 1997-05-16 1998-05-15 胃腸管上部の機能を強化する方法 Expired - Fee Related JP4699576B2 (ja)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US4675497P 1997-05-16 1997-05-16
US60/046,754 1997-05-16
GBGB9715481.9A GB9715481D0 (en) 1997-07-23 1997-07-23 Methods of enhancing functioning of the upper gastrointestinal tract
GB9715481.9 1997-07-23
US09/059,504 US6051557A (en) 1997-05-16 1998-04-13 Methods of enhancing functioning of the upper gastrointestinal tract
US09/059,504 1998-04-13
US9715481.9 1998-04-13
PCT/CA1998/000497 WO1998052600A1 (en) 1997-05-16 1998-05-15 Methods of enhancing functioning of the upper gastrointestinal tract

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009171401A Division JP2009280598A (ja) 1997-05-16 2009-07-22 胃腸管上部の機能を強化する方法

Publications (3)

Publication Number Publication Date
JP2002502369A JP2002502369A (ja) 2002-01-22
JP2002502369A5 JP2002502369A5 (enExample) 2005-07-14
JP4699576B2 true JP4699576B2 (ja) 2011-06-15

Family

ID=27268946

Family Applications (2)

Application Number Title Priority Date Filing Date
JP54974198A Expired - Fee Related JP4699576B2 (ja) 1997-05-16 1998-05-15 胃腸管上部の機能を強化する方法
JP2009171401A Pending JP2009280598A (ja) 1997-05-16 2009-07-22 胃腸管上部の機能を強化する方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009171401A Pending JP2009280598A (ja) 1997-05-16 2009-07-22 胃腸管上部の機能を強化する方法

Country Status (13)

Country Link
EP (1) EP0981362B1 (enExample)
JP (2) JP4699576B2 (enExample)
CN (1) CN1264307B (enExample)
AT (1) ATE253375T1 (enExample)
AU (1) AU746633B2 (enExample)
BR (1) BR9808804A (enExample)
CA (1) CA2289652C (enExample)
DE (1) DE69819488T2 (enExample)
DK (1) DK0981362T3 (enExample)
ES (1) ES2210756T3 (enExample)
MX (1) MXPA99010523A (enExample)
PT (1) PT981362E (enExample)
WO (1) WO1998052600A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009280598A (ja) * 1997-05-16 2009-12-03 1149336 オンタリオ インコーポレーテッド 胃腸管上部の機能を強化する方法

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9905416D0 (en) * 1999-03-09 1999-05-05 Allelix Biopharma Small molecules having GLP-2 like activity
RU2164349C1 (ru) * 1999-07-27 2001-03-20 Нижегородская государственная медицинская академия Способ определения стоматологического статуса
WO2001041779A2 (en) * 1999-12-08 2001-06-14 1149336 Ontario Inc. Combined use of glp-2 receptor agonist and chemotherapeutic agent in treatment
US7186683B2 (en) 2000-09-18 2007-03-06 Sanos Bioscience A/S Use of GLP for the treatment, prevention, diagnosis, and prognosis of bone-related and nutrition-related disorders
PT1326630E (pt) * 2000-09-18 2008-09-02 Sanos Bioscience As Utilização de péptidos glp-2
US7371721B2 (en) 2000-09-18 2008-05-13 Sanos Bioscience A/S Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes
US7411039B2 (en) 2002-10-14 2008-08-12 Novo Nordisk A/S GLP-2 compounds, formulations, and uses thereof
DK1809318T3 (da) 2004-11-01 2013-09-08 Nps Pharma Inc Behandling af korttarmssyndrom-patienter med tyktarmskontinuitet
DE602006020123D1 (de) † 2005-05-04 2011-03-31 Zealand Pharma As Glucagon-like-peptide-2- (glp-2-) analoga
AU2007319066B2 (en) * 2006-11-08 2013-09-19 Zealand Pharma A/S Selective glucagon-like-peptide-2 (GLP-2) analogues
US20110171164A1 (en) * 2008-09-19 2011-07-14 Nektar Therapeutics Polymer conjugates of glp-2-like peptides
JP5908478B2 (ja) * 2010-08-30 2016-04-26 エヌピーエス ファーマシューティカルズ インコーポレイテッドNps Pharmaceuticals, Inc. h「Gly2」GLP−2の固相合成
EA028929B1 (ru) 2012-05-03 2018-01-31 Зилэнд Фарма А/С Аналоги глюкагоноподобного пептида-2 (glp-2)
US20180200301A1 (en) * 2015-05-21 2018-07-19 Shanghai Institutes For Biological Sciences Chinese Academy Of Sciences Low-Oxygen-Treated Mesenchymal Stem Cell and Use Thereof
KR102502040B1 (ko) 2016-12-09 2023-02-24 질랜드 파마 에이/에스 아실화 glp-1/glp-2 이중 효능제
IL271245B2 (en) 2017-06-16 2023-10-01 Zealand Pharma As Dosing regimen for administration of glucagon-like peptide analog (GLP-2) 2
CN108273038B (zh) * 2018-03-16 2019-03-19 中国人民解放军军事科学院军事医学研究院 防治肠型放射病的药物组合物
CN110226566A (zh) * 2019-07-12 2019-09-13 南京中医药大学 一种放射性口腔黏膜炎动物模型的造模方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK27885A (da) * 1985-01-22 1986-07-23 Novo Industri As Fremstilling af peptider
US5990077A (en) * 1995-04-14 1999-11-23 1149336 Ontario Inc. Glucagon-like peptide-2 and its therapeutic use
EP2275438A1 (en) * 1996-04-12 2011-01-19 1149336 Ontario Inc. Glucagon-like peptide-2 analogs
ES2181054T3 (es) * 1996-12-06 2003-02-16 Amgen Inc Utilizacion de producto(s) proteico(s) kgf y de producto(s) proteico(s) glp-2 para la preparacion de un medicamento.
US5952301A (en) * 1996-12-10 1999-09-14 1149336 Ontario Inc. Compositions and methods for enhancing intestinal function
ATE253375T1 (de) * 1997-05-16 2003-11-15 Ontario Inc 1149336 Verwendung von glp-2 agonisten zur verbesserung der wirkung des oberen gastrointestinaltraktes

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009280598A (ja) * 1997-05-16 2009-12-03 1149336 オンタリオ インコーポレーテッド 胃腸管上部の機能を強化する方法

Also Published As

Publication number Publication date
ATE253375T1 (de) 2003-11-15
WO1998052600A9 (en) 2000-03-09
DE69819488D1 (de) 2003-12-11
AU746633B2 (en) 2002-05-02
CA2289652A1 (en) 1998-11-26
DE69819488T2 (de) 2004-08-26
ES2210756T3 (es) 2004-07-01
MXPA99010523A (es) 2004-09-01
AU7516398A (en) 1998-12-11
EP0981362A1 (en) 2000-03-01
BR9808804A (pt) 2001-09-18
JP2002502369A (ja) 2002-01-22
EP0981362B1 (en) 2003-11-05
CN1264307B (zh) 2013-10-30
HK1030160A1 (en) 2001-04-27
CN1264307A (zh) 2000-08-23
PT981362E (pt) 2004-03-31
JP2009280598A (ja) 2009-12-03
WO1998052600A1 (en) 1998-11-26
CA2289652C (en) 2012-02-28
DK0981362T3 (da) 2004-03-15

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