CN1255064A - α－甲基－对－酪氨酸抑制虹膜黑素细胞中黑色素的产生的用途 - Google Patents

α－甲基－对－酪氨酸抑制虹膜黑素细胞中黑色素的产生的用途 Download PDF

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Publication number
CN1255064A
CN1255064A CN98804999A CN98804999A CN1255064A CN 1255064 A CN1255064 A CN 1255064A CN 98804999 A CN98804999 A CN 98804999A CN 98804999 A CN98804999 A CN 98804999A CN 1255064 A CN1255064 A CN 1255064A
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CN
China
Prior art keywords
tyrosine
methyl
alpha
iris
latanoprost
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN98804999A
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English (en)
Chinese (zh)
Inventor
F·德拉戈
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Health AB
Original Assignee
Pharmacia and Upjohn AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn AB filed Critical Pharmacia and Upjohn AB
Publication of CN1255064A publication Critical patent/CN1255064A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN98804999A 1997-04-22 1998-04-21 α－甲基－对－酪氨酸抑制虹膜黑素细胞中黑色素的产生的用途 Pending CN1255064A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI97A000939 1997-04-22
IT97MI000939A IT1291633B1 (it) 1997-04-22 1997-04-22 Uso dell'alfa-metil-p-tirosina per inibire la produzione di melanina nei melanociti dell'iride

Publications (1)

Publication Number Publication Date
CN1255064A true CN1255064A (zh) 2000-05-31

Family

ID=11376994

Family Applications (1)

Application Number Title Priority Date Filing Date
CN98804999A Pending CN1255064A (zh) 1997-04-22 1998-04-21 α－甲基－对－酪氨酸抑制虹膜黑素细胞中黑色素的产生的用途

Country Status (22)

Country Link
US (1) US6359001B1 (https=)
EP (1) EP0977575B1 (https=)
JP (1) JP2001521540A (https=)
KR (1) KR20010020202A (https=)
CN (1) CN1255064A (https=)
AT (1) ATE227577T1 (https=)
AU (1) AU732046B2 (https=)
CA (1) CA2287887A1 (https=)
DE (1) DE69809408T2 (https=)
DK (1) DK0977575T3 (https=)
ES (1) ES2187028T3 (https=)
HU (1) HUP0002100A3 (https=)
IL (1) IL132503A (https=)
IT (1) IT1291633B1 (https=)
NO (1) NO995122L (https=)
NZ (1) NZ500435A (https=)
PL (1) PL189304B1 (https=)
PT (1) PT977575E (https=)
RU (1) RU2218159C2 (https=)
SI (1) SI0977575T1 (https=)
SK (1) SK284255B6 (https=)
WO (1) WO1998047515A1 (https=)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104220057A (zh) * 2012-01-17 2014-12-17 迪美公司 药物组合物和方法
US9549969B2 (en) 2012-01-17 2017-01-24 Tyme, Inc. Pharmaceutical compositions and methods
US10272068B2 (en) 2012-01-17 2019-04-30 Tyme, Inc. Pharmaceutical compositions and methods
US10646552B2 (en) 2012-01-17 2020-05-12 Tyme, Inc. Pharmaceutical compositions and methods
CN116035151A (zh) * 2023-01-18 2023-05-02 云南贝泰妮生物科技集团股份有限公司 一种刺梨闪释粉及其制备方法和应用

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE281432T1 (de) 1999-03-05 2004-11-15 Univ Duke C-16 ungesätigte fp-selektive prostaglandin analoge
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
WO2010087983A1 (en) * 2009-01-29 2010-08-05 Kambiz Thomas Moazed Method and system for effecting changes in pigmented tissue
WO2011011065A1 (en) * 2009-07-22 2011-01-27 Kambiz Thomas Moazed Method and system for effecting changes in pigmented tissue
US9744237B2 (en) * 2009-01-29 2017-08-29 Kambiz Thomas Moazed Method and system for effecting changes in pigmented tissue
US8481498B1 (en) 2012-01-17 2013-07-09 Steven Hoffman Pharmaceutical compositions and methods
US10751313B2 (en) 2013-10-22 2020-08-25 Yamo Pharmaceuticals Llc Compositions and methods for treating autism
US9763903B2 (en) 2013-10-22 2017-09-19 Steven Hoffman Compositions and methods for treating intestinal hyperpermeability
US9585841B2 (en) 2013-10-22 2017-03-07 Tyme, Inc. Tyrosine derivatives and compositions comprising them
US10813901B2 (en) 2013-10-22 2020-10-27 Yamo Pharmaceuticals Llc Compositions and methods for treating autism
US9326962B2 (en) 2013-10-22 2016-05-03 Steven Hoffman Compositions and methods for treating intestinal hyperpermeability
ES2738248B2 (es) * 2018-06-21 2023-03-10 Consejo Superior Investigacion Uso de inhibidores de la tirosina hidroxilasa para el tratamiento del aneurisma de aorta
CN112789045A (zh) 2018-07-19 2021-05-11 亚莫制药有限公司 用于治疗孤独症的组合物和方法
WO2020232227A1 (en) 2019-05-14 2020-11-19 Tyme, Inc. Compositions and methods for treating cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04117313A (ja) * 1990-09-06 1992-04-17 Kanebo Ltd 美白化粧料

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104220057A (zh) * 2012-01-17 2014-12-17 迪美公司 药物组合物和方法
US9549969B2 (en) 2012-01-17 2017-01-24 Tyme, Inc. Pharmaceutical compositions and methods
CN104220057B (zh) * 2012-01-17 2017-11-03 迪美公司 药物组合物和方法
US9895425B2 (en) 2012-01-17 2018-02-20 Tyme, Inc. Pharmaceutical compositions and methods
CN107714684A (zh) * 2012-01-17 2018-02-23 迪美公司 包含α‑甲基‑DL‑酪氨酸的药物组合物及其应用
US10010590B2 (en) 2012-01-17 2018-07-03 Tyme, Inc. Pharmaceutical compositions and methods
US10272068B2 (en) 2012-01-17 2019-04-30 Tyme, Inc. Pharmaceutical compositions and methods
US10307465B2 (en) 2012-01-17 2019-06-04 Tyme, Inc. Pharmaceutical compositions and methods
US10507198B2 (en) 2012-01-17 2019-12-17 Tyme, Inc. Pharmaceutical compositions and methods
US10646552B2 (en) 2012-01-17 2020-05-12 Tyme, Inc. Pharmaceutical compositions and methods
US11052068B2 (en) 2012-01-17 2021-07-06 Tyme, Inc. Pharmaceutical compositions and methods
US11103559B2 (en) 2012-01-17 2021-08-31 Tyme, Inc. Pharmaceutical compositions and methods
CN116035151A (zh) * 2023-01-18 2023-05-02 云南贝泰妮生物科技集团股份有限公司 一种刺梨闪释粉及其制备方法和应用

Also Published As

Publication number Publication date
HUP0002100A2 (hu) 2000-11-28
EP0977575A1 (en) 2000-02-09
SK284255B6 (sk) 2004-12-01
WO1998047515A1 (en) 1998-10-29
DK0977575T3 (da) 2003-03-10
ATE227577T1 (de) 2002-11-15
AU732046B2 (en) 2001-04-12
CA2287887A1 (en) 1998-10-29
NO995122D0 (no) 1999-10-21
ITMI970939A0 (https=) 1997-04-22
IL132503A (en) 2004-06-20
PL189304B1 (pl) 2005-07-29
US6359001B1 (en) 2002-03-19
RU2218159C2 (ru) 2003-12-10
IL132503A0 (en) 2001-03-19
PL336386A1 (en) 2000-06-19
JP2001521540A (ja) 2001-11-06
DE69809408T2 (de) 2003-07-10
AU7646298A (en) 1998-11-13
ES2187028T3 (es) 2003-05-16
SK142499A3 (en) 2000-09-12
HUP0002100A3 (en) 2003-05-28
PT977575E (pt) 2003-03-31
SI0977575T1 (en) 2003-04-30
ITMI970939A1 (it) 1998-10-22
IT1291633B1 (it) 1999-01-11
NZ500435A (en) 2001-09-28
NO995122L (no) 1999-12-21
DE69809408D1 (de) 2002-12-19
EP0977575B1 (en) 2002-11-13
KR20010020202A (ko) 2001-03-15

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