CN1238003C - Lotion for treating anus disease and production method - Google Patents
Lotion for treating anus disease and production method Download PDFInfo
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- CN1238003C CN1238003C CN 02125093 CN02125093A CN1238003C CN 1238003 C CN1238003 C CN 1238003C CN 02125093 CN02125093 CN 02125093 CN 02125093 A CN02125093 A CN 02125093A CN 1238003 C CN1238003 C CN 1238003C
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Abstract
The present invention relates to lotion for treating anorectal diseases and a producing method. The lotion comprises the raw materials with the percentage content by weight of each component: 14 to 17% of zanthoxylum, 14 to 17% of glycyrrhiza, 14 to 17% of burnet, 14 to 17% of mirabilite, 14 to 17% of parsnip and 16 to 29% of amur corktree bark. The producing method of the lotion comprises: the raw materials are weighed proportionally and are respectively pulverized into a powder state, and are then mixed together so as to be put into a nylon bag; the nylon bag is put into an extracting tank of traditional Chinese medicine so as to be soaked for 40 minutes after water is added; the soaked medicine is heated and boiled for 45 minutes, and medical liquids are stand-by after filtered by gauze; water is added into the extracting tank once again, medical dregs are extracted and dried after the nylon bag is boiled for 45 minutes once again, and the medical liquids are filtered by gauze so as to leave the medical liquids behind for stand-by; the two times of medical liquids are mixed and are concentrated into brown liquids, and a finished product is put into a bottle and is sealed so as to be sterilized for 30 minutes and stored by putting in a shady and dry place. The present invention has the advantages of simple producing method, convenient use, painlessness and high cure rate.
Description
Technical field
The present invention relates to a kind of external-use lotion for the treatment of anal and intestinal disease, particularly a kind of lotion and production method for the treatment of treatment such as hemorrhoid complicated by anal fistula anal and intestinal disease.
Background technology
Anal and intestinal diseases such as hemorrhoid complicated by anal fistula are commonly encountered diseases, frequently-occurring disease.Although multiple treatment means is all arranged, return its class can be divided into two kinds of non-operative treatment and operative therapys for hemorrhoid and fistula motherland medical science and foreign medical science.Non-operative treatment can play and diminish inflammation, mitigation symptoms, control development, basic effect of curing.Operative therapy then can reach radical cure.The fumigation and wash method method is a kind of non-operative treatment of anal and intestinal diseases such as motherland's therapeutic treatment hemorrhoid complicated by anal fistula, plays the effect of heat-clearing and toxic substances removing, reducing swelling and alleviating pain, astringing to arrest bleeding, the parasite killing that dries, putrefaction removing life by fumigation and wash method.No matter adopt operation still to adopt the non-operative treatment treatment all to need medication that wound is carried out fumigation and wash method, although yet there are no report with the Chinese medicine fumigation and washing anal and intestinal disease such as hemorrhoid complicated by anal fistula for the treatment of as lotion with six kinds of pure Chinese medicines such as Cortex Phellodendri, Fructus Zanthoxyli on the books.
Summary of the invention
The object of the present invention is to provide a kind of is raw material with Cortex Phellodendri, Fructus Zanthoxyli, Radix Saposhnikoviae, Natrii Sulfas, Radix Sanguisorbae, Radix Glycyrrhizae Six-element Chinese medicine, and be made into lotion, have the lotion and the production method of the treatment anal and intestinal diseases such as treatment hemorrhoid complicated by anal fistula of heat-clearing and toxic substances removing, reducing swelling and alleviating pain, astringing to arrest bleeding, the parasite killing that dries, putrefaction removing life effect.
The object of the present invention is achieved like this: the raw material that constitutes lotion is made up of Fructus Zanthoxyli, Radix Glycyrrhizae, Radix Sanguisorbae, Natrii Sulfas, Radix Saposhnikoviae, Cortex Phellodendri, and the weight percent content of each component is Fructus Zanthoxyli 14-17%, Radix Glycyrrhizae 14-17%, Radix Sanguisorbae 14-17%, Natrii Sulfas 14-17%, Radix Saposhnikoviae 14-17%, Cortex Phellodendri 16-29%.
The weight percent content that constitutes the lotion raw material components is a Fructus Zanthoxyli 16.7%, Radix Glycyrrhizae 16.6%, Radix Sanguisorbae 16.7%, Natrii Sulfas 16.7%, Radix Saposhnikoviae 16.6%, Cortex Phellodendri 16.7%.
Each raw material also can equivalent add.
The production method of the lotion of described treatment anal and intestinal disease, undertaken by following step:
1, weighing Six-element raw material of Chinese medicine and their pulverize separately are become powder at first in proportion mixes them then, in the Nylon Bag of packing into, and all loose tying of each bag.
2, Nylon Bag is put into the Chinese medicine extraction jar, soaked 40 minutes, the addition of water will suit, and exceed medicamental pulverata.
3, the medicine heated and boiled that will be soaked is 45 minutes, then with medicinal liquid with three layers of filtered through gauze, it is standby to emit medicinal liquid.
4, in extraction pot, add water once more, and after it is boiled 45 minutes once more, propose medicinal residues and drench and do, then with medicinal liquid with three layers of filtered through gauze, it is standby to stay medicinal liquid.
5, with twice medicinal liquid mixing simmer down to brown liquid, with the finished product sealing in the bottle of packing into, every bottle of 500ml, flowing steam sterilization get final product in 30 minutes, put shady and cool dry place and preserved.
Compared to existing technology, advantage of the present invention is: the present invention is dense fried dose, and medicine source is extensive, and stable in properties is not volatile.Do not produce chemical reaction, not perishable.The present invention is applied to for many years clinical, has the function of heat-clearing and toxic substances removing, reducing swelling and alleviating pain, astringing to arrest bleeding, the parasite killing that dries, putrefaction removing life through clinical verification.And inhibiting bacteria and diminishing inflammation is arranged, promote the effect of wound healing, best with the reducing swelling and alleviating pain effect.Flavour of a drug of the present invention are few, and medicine source foot is cheap, does not need decoct every day, and is easy to use, reliable for effect.
The specific embodiment
Below in conjunction with embodiment in detail the present invention is described in detail.
The present invention is made up of Fructus Zanthoxyli, Radix Glycyrrhizae, Radix Sanguisorbae, Natrii Sulfas, Radix Saposhnikoviae, Cortex Phellodendri.The weight percent content of each component is Fructus Zanthoxyli 14-17%, Radix Glycyrrhizae 14-17%, Radix Sanguisorbae 14-17%, Natrii Sulfas 14-17%, Radix Saposhnikoviae 14-17%, Cortex Phellodendri 16-29%.Except that inferior, but the adding of Six-element medicine equivalent, and embodiment (weight) is as follows:
Fructus Zanthoxyli 6000g, Radix Glycyrrhizae 6000g, Radix Sanguisorbae 6000g, Natrii Sulfas 6000g, Radix Saposhnikoviae 6000g, Cortex Phellodendri 6000g.
The weight percent content of each component is represented with following table:
| Title | Weight percent content (%) | |||||
| Fructus Zanthoxyli | 16.7 | 17 | 15 | 17 | 14 | 15 |
| Radix Glycyrrhizae | 16.6 | 17 | 14 | 16 | 15 | 15 |
| Radix Sanguisorbae | 16.7 | 14 | 14 | 15 | 17 | 15 |
| Natrii Sulfas | 16.7 | 15 | 14 | 17 | 16 | 15 |
| Radix Saposhnikoviae | 16.6 | 14 | 14 | 15 | 17 | 15 |
| Cortex Phellodendri | 16.7 | 23 | 29 | 20 | 21 | 25 |
| Add up to | 100 | 100 | 100 | 100 | 100 | 100 |
The pharmacological action that constitutes each component of the present invention is:
Fructus Zanthoxyli: hot, heat, poisonous.Go into spleen, stomach warp.Have warming middle-JIAO to relieve pain, detoxifcation, parasite killing diuresis, detumescence effect.Be used for the abdomen cold type of pain due to the Deficiency and coldness of spleen and stomach, stomachache that causes because of ascarid etc.This medicine has inhibitory action to escherichia coli, dysentery bacterium and dermatophytes, local anesthesia and pain relieving is arranged and kill the effect of ascarid.
Cortex Phellodendri: bitter, tremble with fear, go into kidney, spleen channel.Heat clearing and damp drying, clear asthenic fire are arranged, separate effect such as pyretic toxicity.According to the medicine antibacterial experiment, this product is the strongest to the antibacterial action of dysentery bacterium, and dermatophytes is had inhibitory action.
Radix Saposhnikoviae: hot, sweet, tepor, go into bladder, liver, spleen channel.Inducing diaphoresis to dispel wind is arranged, the pain relieving of drying, effects such as detoxifcation.Be used to the disease of itching, stomachache, hemorrhoid complicated by anal fistula swell and ache etc., and dysentery bacterium is had stronger inhibitory action, diaphoresis is arranged, detoxify, dispel the wind, analgesic activity.
Natrii Sulfas: salty, little hardship, cold.Go into stomach, large intestine channel.The softening the hard mass relieving constipation is arranged, heat-clearing and toxic substances removing, effects such as reducing swelling and alleviating pain.For oral administration be used for the intenseness of heat constipation, external can be controlled aphtha of the mouth and tongue, swelling and pain of hemorrhoid etc.This product is difficult for being absorbed by intestinal wall, forms the high saline solution that oozes after intestinal is dissolved in water, thereby makes intestinal keep a large amount of moisture, stimulates intestinal peristalsis promoting and defecation.
Radix Sanguisorbae: bitter, acid, be slightly cold.Go into liver, stomach, large intestine channel.The hemostasis of the amount of having blood, clearing heat for detumescence, the convergence granulation promoting promotes effects such as wound healing.This product contains a large amount of tannins, and ulcer surface is had astriction, and can suppress staphylococcus, bacillus pyocyaneus, to burn, mucocutaneous inflammation, can control infection and prevent toxemia, and can reduce and ooze out, promote new skin growth.
Radix Glycyrrhizae: sweet, flat, 82 warps.Invigorating the spleen and replenishing QI is arranged, heat-clearing and toxic substances removing, treating stranguria, nourishing the lung to arrest cough, the mediation property of medicine is alleviated effects such as pain relieving.Be used for deficiency of the spleen causing weakness of QI, skin infection swells and ache etc.This product contains glycyrrhizin, and stronger Detoxication is arranged, and tubercule bacillus is had inhibitory action.
Production method embodiment of the present invention:
The present invention presses following step processing:
1, weighing Six-element raw material of Chinese medicine and their pulverize separately are become powder at first in proportion mixes them then, in the Nylon Bag of packing into, and all loose tying of each bag.
2, Nylon Bag is put into the Chinese medicine extraction jar, soaked 40 minutes, the addition of water will suit, and exceed medicamental pulverata.
3, the medicine heated and boiled that will be soaked is 45 minutes, then with medicinal liquid with three layers of filtered through gauze, it is standby to emit medicinal liquid.
4, in extraction pot, add water once more, and after it is boiled 45 minutes once more, propose medicinal residues and drench and do, then with medicinal liquid with three layers of filtered through gauze, it is standby to stay medicinal liquid.
5, with twice medicinal liquid mixing simmer down to brown liquid, with the finished product sealing in the bottle of packing into, every bottle of 500ml, flowing steam sterilization get final product in 30 minutes, put shady and cool dry place and preserved.
Using method of the present invention: divide five uses, 100ml adds boiling water 900ml once a day, smokes afterwards earlier and washes.
Treatment curative effect statistical analysis of the present invention is represented with following table:
240 routine curative effect statistical tables are organized in table 1 operation
| Symptom | Symptom before the fumigation and wash method | Symptom variation behind the fumigation and wash method | |||||||
| The example number | ％ | Produce effects | ％ | Effectively | ％ | Invalid | ％ | Effective percentage | |
| Pain | 239 | 99.7 | 161 | 67.4 | 78 | 32.6 | 100 | ||
| The anus tenesmus | 105 | 43.75 | 90 | 78.26 | 15 | 21.74 | 100 | ||
| The rectum tenesmus | 26 | 10.8 | 24 | 92.31 | 2 | 7.89 | 100 | ||
| Have blood in stool | 147 | 61.25 | 122 | 83.06 | 22 | 14.9 | 3 | 2.04 | 100 |
| Anus edge edema | 43 | 13.75 | 25 | 58.14 | 18 | 41.86 | 100 | ||
| The anus edge is swollen hard | 70 | 29.2 | 58 | 82.86 | 9 | 12.86 | 3 | 4.28 | 95.72 |
| Wound is unclean | 191 | 79.7 | 113 | 53.92 | 78 | 46.8 | 100 | ||
| Total effective rate | 98.97％ | ||||||||
The non-operation 60 routine curative effect statistical tables of table 2
| Symptom | Symptom before the fumigation and wash method | Change behind the fumigation and wash method | Effective percentage | Total effective rate | ||||||
| The example number | ％ | Produce effects | ％ | Effectively | ％ | Invalid | ％ | |||
| Pain | 60 | 100 | 32 | 51.6 | 28 | 48.4 | 100 | 98.29 | ||
| The anus tenesmus | 33 | 55 | 19 | 57.6 | 14 | 42.4 | 100 | |||
| The rectum tenesmus | 12 | 20 | 10 | 83.3 | 2 | 16.7 | 100 | |||
| Have blood in stool | 9 | 15 | 3 | 33.4 | 6 | 66.6 | 100 | |||
| Anus edge edema | 22 | 36.6 | 16 | 72.7 | 6 | 27.3 | 100 | |||
| The anus edge is swollen hard | 25 | 41.6 | 10 | 40 | 12 | 48 | 3 | 12 | 88 | |
| Breach | 7 | 11.6 | 2 | 28.5 | 5 | 71.5 | 100 | |||
Table 3 matched group P.P water 100 routine curative effect statistical tables
| Symptom | Symptom before the fumigation and wash method | Symptom behind the fumigation and wash method | Effective percentage | Total effective rate | ||||
| The example number | ％ | Effectively | ％ | Invalid | ％ | |||
| Pain | 93 | 98 | 76 | 77.55 | 22 | 22.45 | 77.55 | 65.04 |
| The anus tenesmus | 27 | 27 | 16 | 59.26 | 11 | 40.74 | 52.26 | |
| The rectum tenesmus | 7 | 7 | 4 | 57.14 | 3 | 42.86 | 57.14 | |
| Have blood in stool | 55 | 55 | 29 | 52.73 | 26 | 47.27 | 52.78 | |
| Anus edge edema | 31 | 31 | 23 | 74.2 | 8 | 25.8 | 74.2 | |
| The anus edge is swollen hard | 24 | 24 | 17 | 70.8 | 7 | 27.2 | 72.8 | |
| Wound is unclean | 58 | 58 | 36 | 61.6 | 22 | 38.4 | 61.6 | |
Table 4 wound is observed table
Table 5 leukocyte changes observes table
Through significance test, the operation group of treatment group is compared with matched group, and μ is greater than μ 0.01.P illustrates that non-operation group and the matched group curative effect in the treatment group has significant difference, through X less than 0.01
3Check, non-operation group in the treatment group and matched group compare, X
2Greater than X
20.01 P illustrates that less than 0.01 non-operation group and the matched group curative effect in the treatment group has significant difference.Through X
2Check, operation group in the treatment group and non-operation group compare, X
2Greater than 3.84, P is less than 0.05, and illustrating between two groups does not have significant difference.
The present invention is through the check of institute for drug control, Tangshan City, and pH value, relative density, microbial limit three-phase index all meet each pertinent regulations under " Chinese pharmacopoeia " appendix mixture item.
Claims (4)
1, a kind of lotion for the treatment of anal and intestinal disease, it is characterized in that, the raw material that constitutes lotion is made up of Fructus Zanthoxyli, Radix Glycyrrhizae, Radix Sanguisorbae, Natrii Sulfas, Radix Saposhnikoviae, Cortex Phellodendri, the weight percent content of raw material components is Fructus Zanthoxyli 14-17%, Radix Glycyrrhizae 14-17%, Radix Sanguisorbae 14-17%, Natrii Sulfas 14-17%, Radix Saposhnikoviae 14-17%, Cortex Phellodendri 16～29%.
2, the lotion of treatment anal and intestinal disease according to claim 1 is characterized in that, the weight percent content that constitutes the lotion raw material components is Fructus Zanthoxyli 16.7%, Radix Glycyrrhizae 16.6%, Radix Sanguisorbae 16.7%, Natrii Sulfas 16.7%, Radix Saposhnikoviae 16.6%, Cortex Phellodendri 16.7%.
3, the lotion of treatment anal and intestinal disease according to claim 1 is characterized in that, each raw material also can equivalent add.
4, a kind of production method of lotion of treatment anal and intestinal disease as claimed in claim 1 is characterized in that, it is undertaken by following step:
A, weighing Six-element raw material of Chinese medicine and their pulverize separately are become powder at first in proportion mix them, in the Nylon Bag of packing into, with the loose tying of bag then;
B, Nylon Bag is put into the Chinese medicine extraction jar, soaked 40 minutes;
C, the medicine heated and boiled that will be soaked 45 minutes, then with medicinal liquid with filtered through gauze after, it is standby to emit medicinal liquid;
D, add water once more in extraction pot, and after it is boiled 45 minutes once more, propose medicinal residues and drench and do, with the medicinal liquid filtered through gauze, it is standby to stay medicinal liquid then;
E, with twice medicinal liquid mixing simmer down to brown liquid, with the finished product sealing in the bottle of packing into, flowing steam sterilization get final product in 30 minutes, put shady and cool dry place and preserved.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02125093 CN1238003C (en) | 2002-07-12 | 2002-07-12 | Lotion for treating anus disease and production method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02125093 CN1238003C (en) | 2002-07-12 | 2002-07-12 | Lotion for treating anus disease and production method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1466967A CN1466967A (en) | 2004-01-14 |
| CN1238003C true CN1238003C (en) | 2006-01-25 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02125093 Expired - Lifetime CN1238003C (en) | 2002-07-12 | 2002-07-12 | Lotion for treating anus disease and production method |
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| Country | Link |
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| CN (1) | CN1238003C (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102727643B (en) * | 2012-06-20 | 2014-04-02 | 中国中医科学院广安门医院 | Medicine for treating hemorrhoid and alleviating ache and oedema after haemorrhoidectomy and preparation method thereof |
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2002
- 2002-07-12 CN CN 02125093 patent/CN1238003C/en not_active Expired - Lifetime
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| CN1466967A (en) | 2004-01-14 |
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