CN106362077B - Chinese medicine for treating burn, scald and skin trauma and its preparing process - Google Patents

Chinese medicine for treating burn, scald and skin trauma and its preparing process Download PDF

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CN106362077B
CN106362077B CN201610951027.8A CN201610951027A CN106362077B CN 106362077 B CN106362077 B CN 106362077B CN 201610951027 A CN201610951027 A CN 201610951027A CN 106362077 B CN106362077 B CN 106362077B
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medicinal materials
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chinese medicinal
borneol
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CN106362077A (en
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朱铁山
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/732Chaenomeles, e.g. flowering quince
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9064Amomum, e.g. round cardamom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention discloses a Chinese medicament for treating burns, scalds and skin trauma and a preparation method thereof, and is characterized in that: mainly comprises the following Chinese medicinal materials: the weight ratio of the coptis, the fructus amomi, the pawpaw, the borneol, the frankincense and the myrrh is 1: 1. The preparation method comprises the following steps: weighing the above medicines according to the weight ratio of the Chinese medicinal materials, respectively drying the coptis chinensis, the fructus amomi, the pawpaw, the frankincense and the myrrh, then mixing the dried Chinese medicinal materials with the borneol, uniformly mixing, grinding into powder, sieving by a 80-mesh sieve, finishing the processing, and sieving by the 80-mesh sieve to obtain the powder as a processed finished product. Compared with the prior art, the invention has the advantages that: the medicine of the invention adopts a pure traditional Chinese medicine external application mode, the wound surface is healed quickly, the treatment process is simple and convenient, the wound surface does not need to be debrided and changed with medicine repeatedly and a large amount of antibiotics are used for antibiosis, particularly for III-degree burns and scalds, the skin grafting operation treatment is not needed, and the pain and the economic burden of the patient caused by the operation are reduced to a great extent.

Description

Chinese medicine for treating burn, scald and skin trauma and its preparing process
Technical Field
The invention relates to the technical field of medicine industry, in particular to a traditional Chinese medicine for treating burns, scalds and skin trauma and a preparation method thereof.
Background
Burn and scald are traumatic diseases which are injured by external factors such as fire, water, electricity and the like, can bring great pain and irrecoverable scars to patients, and greatly influence the later life of the patients, so how to improve the treatment effect of the disease is important, the burn and scald are both fire toxin or heat toxin, the treatment method mainly regenerates muscle and skin tissues through medicines, the skin trauma comprises scraping, incision and the like caused by mechanical reasons, and the treatment principle is that the muscle and skin tissues are regenerated through medicines to achieve the purpose of healing.
In the prior art, the treatment means is that the skin and muscle tissues are regenerated to realize physiological healing by injecting or orally taking antibiotics for antibiosis while externally applying the medicine to the wound surface. For treating burns and scalds, the existing adopted treatment means have the objective defects that: in the treatment process, the wound surface needs to be debrided and changed with medicine repeatedly and a large amount of antibiotics are used for antibiosis, the time needed for healing is long, scars are easy to leave after healing, particularly for III-degree burns and scalds, a skin grafting operation treatment means needs to be adopted, and great pain and economic burden are brought to patients; in the treatment of mechanical skin trauma, there are objective disadvantages: the wound is required to be sutured, the wound surface is repeatedly debrided and changed with medicine for a plurality of times, and meanwhile, a large amount of antibiotics are used for antibiosis, so that the healing time is long, and great pain and economic burden are brought to patients; for skin and meat rot diseases such as bedsore and diabetic foot, a treatment medicament with good treatment effect is not available at present.
Disclosure of Invention
The invention aims to overcome the technical defects and provide a traditional Chinese medicine for treating burns, scalds and skin trauma, which has simple medicinal components, convenient treatment process and good treatment effect, and a preparation method thereof.
In order to solve the technical problems, the technical scheme provided by the invention is as follows: a traditional Chinese medicine for treating burns, scalds and skin trauma mainly comprises the following traditional Chinese medicinal materials: the weight ratio of the coptis, the fructus amomi, the pawpaw, the borneol, the frankincense and the myrrh is 1: 1.
The preparation method of the medicine comprises the steps of weighing the medicine according to the weight ratio of the Chinese medicinal materials, drying the coptis chinensis, the fructus amomi, the pawpaw, the frankincense and the myrrh respectively, then mixing the dried Chinese medicinal materials with the borneol, grinding the mixture into powder after uniformly mixing, sieving the powder by a 80-mesh sieve to complete the processing, and sieving the powder by the 80-mesh sieve to obtain the processed finished product.
Compared with the prior art, the invention has the advantages that: the medicine formula of the invention adopts a mode of externally using pure traditional Chinese medicine compatibility, when in use, the prepared medicine powder is externally applied on the wound surface of a patient, pain can be relieved within about 10 minutes, the wound surface is scabbed within 24 hours, skin and muscle tissues are regenerated under the protection of scab shells, after the regeneration is finished, the scab shells naturally fall off, and the wound surface is healed as before without scars; the wound surface is healed more quickly, the treatment process is simple and convenient, the wound surface does not need to be debrided and changed with medicine repeatedly and a large amount of antibiotics are used for antibiosis; especially for III degree burns and scalds, the skin grafting operation treatment is not needed. Therefore, the pain and the economic burden of a patient in the treatment process are greatly relieved, the aversion to wind caused by the abuse of antibiotics can be effectively restrained, the pharmaceutical composition has great social significance, and the blank that the drugs with good treatment effects are lacked for treating the skin and meat rot diseases such as bedsore, diabetic foot and the like is filled.
Detailed Description
The present invention will be described in further detail with reference to examples.
Coptis chinensis: the second record of the thirteenth volume of herbs in the ministry of herbage: huang Lian, Sheng Wu Yang Chuan Gu and Shu county Taishan Yang, February and August, its root is connected with pearl and yellow in color, so the name is. Bitter, cold and non-toxic. It can be used for sores, abscess, deep-rooted carbuncle, swelling and toxin, ulcerated or non-ulcerated. The Chinese pharmacopoeia (2015 part) records: coptis chinensis [ function and indication ]: clear heat and dry dampness, purge fire and remove toxicity, treat abscess, furuncle and eczema.
Borneol: the record of the Chinese herbal compendium on the Chinese herbal medicine of borneol in the department of wood: borneol, veronicastrum seed, veronicastrum herb, etc. its name is veronicastrum herb (according to the modern general name of borneol) which is pungent, bitter, slightly cold and non-toxic. It can be used for treating sore and ulcer with swelling and pain, and unhealing ulcer. The Chinese pharmacopoeia (2015 part) records: borneol [ function and indication ]: clear heat and alleviate pain.
Amomum fruit: the record of Amomum villosum in Shi Ju of compendia of materia Medica: sha ren is warm in nature, pungent in flavor, fragrant and dampness-resolving. Modern pharmaceutical research shows that: fructus Amomi has antiulcer effect.
Pawpaw: the Chinese flowering quince in the fruit department of compendium of materia medica records: acid, warm and non-toxic. The Chinese pharmacopoeia (2015 part) records: papaya [ function and indication ]: relaxing tendons and activating collaterals, beriberi and edema.
Myrrh: record of myrrh in the wooden part of materia medica compendium: the Bos country of origin. The blocks are of variable size, black, and like benzoin. [ ODOUR ] bitter, mild and nontoxic. [ INDICATIONS ] can break blood and relieve pain, and treat skin ulcer, canker sore, and anal fistula. The Chinese pharmacopoeia (2015 part) records: myrrh [ function and indications ]: dispel stasis and relieve pain, resolve swelling and promote granulation, and is indicated for carbuncle, swelling and sores.
Frankincense: record of frankincense in xylem of compendium of materia medica: the resin is bitter and warm in nature and is non-toxic. [ INDICATIONS ] has effects of promoting blood circulation, relieving pain, and eliminating carbuncle and cellulitis. The Chinese pharmacopoeia (2015 part) records: myrrh [ function and indications ]: promoting blood circulation to stop pain, subduing swelling and promoting granulation, and abscess, sores and ulcers.
The six medicinal materials are compatible, have strong antibacterial action, are used for wound surfaces, promote blood circulation to stop pain, diminish inflammation and promote tissue regeneration, and can quickly promote muscle and skin tissue regeneration.
A traditional Chinese medicine for treating burns, scalds and skin trauma mainly comprises the following traditional Chinese medicinal materials: the weight ratio of the coptis, the fructus amomi, the pawpaw, the borneol, the frankincense and the myrrh is 1: 1.
The manufacturing method comprises the following steps: weighing the above medicines according to the weight ratio of the Chinese medicinal materials, respectively drying the coptis chinensis, the fructus amomi, the pawpaw, the frankincense and the myrrh, then mixing the dried Chinese medicinal materials with the borneol, uniformly mixing, grinding into powder, sieving by a 80-mesh sieve, finishing the processing, and sieving by the 80-mesh sieve to obtain the powder as a processed finished product.
The medicine of the invention has the advantages that:
1. the pure Chinese medicinal preparation is externally used and has no toxic or side effect;
2. is suitable for treating burn, scald, skin trauma, incision wound caused by mechanical reasons, bedsore and skin and meat rot caused by various reasons;
3. has faster effect and better treatment effect. The prepared medicinal powder can relieve pain after being applied to the wound of a patient for about 10 minutes, and most of burns and scalds of i, ii and iii degrees can be cured within about two weeks by adopting the medicine for treatment, and no scar is left after the cure. Greatly shortens the treatment time of the burns and scalds, relieves the pain and the treatment cost of patients caused by the treatment process, and effectively improves the treatment effect;
4. the use is more convenient. After the patient takes the medicine, the wound can rapidly scab within 24 hours. Particularly, the mechanical trauma does not need to be sutured, the wound does not need to be debrided and changed with dressings repeatedly for many times, the scab can be healed after the scab naturally falls off, and the pain of a patient caused by suturing the wound and repeatedly debriding and changing dressings of the wound is relieved to a greater extent;
5. the traditional Chinese medicine has the effects of removing putrefaction, removing dirt, removing purulence, detoxifying, diminishing inflammation and promoting tissue regeneration, and for skin and meat rotting diseases caused by various reasons, the medicinal powder is directly externally applied to the surface of a wound and directly acts on the wound to take effect, so that the traditional Chinese medicine is used when a patient does not have large-area serious infection, does not need to simultaneously use a large amount of antibiotic for antibiosis, can effectively inhibit the pernicious wind caused by the abuse of the antibiotic at present, and has great social significance;
6. fills the blank that the skin and meat rot diseases such as bedsore, diabetic foot and the like lack of medicaments with good treatment effect.
Example one
Patient king xx, female, 32 years old. 13-day burn at 8-month in 2007, and the wound condition is: the burn of the superficial II degrees of the face, the deep II degrees of burns of the elbows, the legs and the feet of the left upper limb, the double lower limbs and the double feet is treated by adopting the medicament of the invention, the 8-21-day in 2007, and the condition of the wounded face after two weeks after the medicament is used is diagnosed as follows: the dead skin of the face falls off, the new skin grows as long as no scar is left, most of the dead skin of the elbow of the left upper limb falls off, the new skin grows as long as the local wound is scabbed to be fallen off, and the face is basically healed. No antibiotics were injected or administered orally throughout the treatment.
Example two
Patient suxx, female, 70 years old. 13-day burn at 8-month in 2007, and the wound condition is: the deep ii-degree burns of the lower right arm, elbow, lower legs and feet are treated by the medicament, the condition of the injured face is diagnosed after the medicament is used for treating the deep ii-degree burns in 8-21 days in 2007, two weeks after the medicament is used: the crusts of the lower arm of the right upper limb and the elbow fall off, and the wound surface is healed without scars when new skin grows. No antibiotics were injected or administered orally throughout the treatment.
EXAMPLE III
Patient Liu xx, female, 26 years old. 13-day burn at 8-month in 2007, and the wound condition is: the deep ii degree burns of the lower arms, the waist and the abdomen, the lower limbs and the feet of the left upper limb are treated by adopting the medicament, the condition of the injured surface after diagnosis is that the condition is that the injured surface is treated by the medicament after 8, 21 days in 2007 and two weeks after the medicament is used: the abdominal dead skin comes off, new skin grows out, the wound surface is healed without scars, most of the dead skin of both lower limbs and both feet comes off, new skin grows out, local wound surface scabs is formed, and the wound surface condition is diagnosed after the falling-off, 9 months and 1 day in 2007 and three weeks after the administration: the dead skin of both lower limbs and both feet falls off, new skin grows out, the wound surface is healed, and no scar is left. No antibiotics were injected or administered orally throughout the treatment.
Example four
Patient Chua xx, male, 48 years old. In 2016, 6 months and 28 days, the patient is scalded by the silencer at the right ankle part of the motorcycle, and after 9 days of hospital treatment, the wound is not improved, and is inflamed and ulcerated and reaches the dermis. The medicine is used for treatment in 2016, 7 and 7 days, and the wound condition after diagnosis is carried out 24 hours after the medicine is used in 2016, 7 and 8 days: the wound is basically scabbed, the red swelling around the wound subsides, the scab shell naturally falls off in about one week, and the wound is healed. No antibiotics were injected or administered orally throughout the treatment.
EXAMPLE five
Patient yao xx, female, 44 years old. 7-23 days in 2016, the inner sides of the lower legs of the left limbs of a patient are scalded due to moxibustion, after the patients are treated in a hospital for 9 days, the wound surfaces are not improved, two parts of the wound surfaces are ulcerated, the wound surfaces are deep to muscles, the periphery of the wound is red and swollen and is in a pyogenic infection state, the treatment by using the medicine of the invention is started in 2016, 8 and 3 days in 2016, and the wound surface condition is diagnosed 72 hours after the medicine is taken: the red swelling around the wound is eliminated, the wound is completely scabbed, and the scab shell falls off naturally after 7-10 days, so that the wound is healed without scars. No antibiotics were injected or administered orally throughout the treatment.
The invention and its embodiments have been described above, but the description is not limitative, and the examples show only one of the embodiments of the invention. In summary, those skilled in the art should appreciate that they can readily use the disclosed conception and specific embodiments as a basis for designing or modifying other structures for carrying out the same purposes of the present invention without departing from the spirit and scope of the invention as defined by the appended claims.

Claims (2)

1. A traditional Chinese medicine for treating burns, scalds and skin trauma is characterized in that: the traditional Chinese medicine composition is composed of the following traditional Chinese medicinal materials: the weight ratio of the coptis, the fructus amomi, the pawpaw, the borneol, the frankincense and the myrrh is 1: 1.
2. A method for preparing the traditional Chinese medicine of claim 1, which is characterized by comprising the following steps: weighing the above medicines according to the weight ratio of the Chinese medicinal materials, respectively drying the coptis chinensis, the fructus amomi, the pawpaw, the frankincense and the myrrh, then mixing the dried Chinese medicinal materials with the borneol, uniformly mixing, grinding into powder, sieving by a 80-mesh sieve, finishing the processing, and sieving by the 80-mesh sieve to obtain the powder as a processed finished product.
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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1394622A (en) * 2001-07-06 2003-02-05 赵兰洲 Medicine for curing burn and scald
CN1554373A (en) * 2003-12-26 2004-12-15 王克馥 Medicine for treating brun and scald and preparing method
CN1785291A (en) * 2004-12-10 2006-06-14 崔庆智 Medicine for treating burn and scald and its prepartion method
CN102327478A (en) * 2011-09-28 2012-01-25 韩树华 Pharmaceutical composition for treating burns and scalds and preparation method thereof
CN103816247A (en) * 2012-11-19 2014-05-28 中国人民解放军总医院 External Chinese medicinal composition capable of preventing scarring healing of external injury and preparation method for external Chinese medicinal composition

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1394622A (en) * 2001-07-06 2003-02-05 赵兰洲 Medicine for curing burn and scald
CN1554373A (en) * 2003-12-26 2004-12-15 王克馥 Medicine for treating brun and scald and preparing method
CN1785291A (en) * 2004-12-10 2006-06-14 崔庆智 Medicine for treating burn and scald and its prepartion method
CN102327478A (en) * 2011-09-28 2012-01-25 韩树华 Pharmaceutical composition for treating burns and scalds and preparation method thereof
CN103816247A (en) * 2012-11-19 2014-05-28 中国人民解放军总医院 External Chinese medicinal composition capable of preventing scarring healing of external injury and preparation method for external Chinese medicinal composition

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