CN105250712A - Traditional Chinese medicine composition for treating bedsores - Google Patents
Traditional Chinese medicine composition for treating bedsores Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating bedsores. The traditional Chinese medicine composition is prepared from, by weight, 8-12 parts of Yunnan Baiyao, 15-25 parts of astragalus membranaceus, 8-12 parts of ligusticum wallichii, 8-12 parts of pseudo-ginseng, 3-8 parts of golden cypress, 3-8 parts of radix sanguisorbae and 15-25 parts of calcined gypsum. According to the traditional Chinese medicine composition, Yunnan Baiyao, astragalus membranaceus, ligusticum wallichii, pseudo-ginseng, golden cypress, radix sanguisorbae and calcined gypsum are compatible and work together to achieve the effect of treating the bedsores, obvious synergism is achieved, the compatibility relationships of mutual promotion and mutual enhancement are given full play, and the bedsores can be effectively treated. After the traditional Chinese medicine composition is applied, pus seepage is decreased, the wound surface is kept dry, incrustation is formed quickly, time for wound surface healing is shortened, expense is saved, nursing operation is simple and convenient, time and labor are saved, a patient has no adverse reaction, clinical care working load is alleviated, and the application scope is wide.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, be specifically related to a kind of Chinese medicine composition for the treatment of decubital ulcer.
Background technology
Pressure ulcer, also known as pressure ulcer, decubital ulcer, is due to the long-term pressurized of local organization, and continuous ischemia, anoxia, malnutrition and cause tissue fester's necrosis occur.Pressure ulcer is the problem of a universality in rehabilitation, nursing.
Clinical syndrome differentiation is divided into qi depression to blood stasis, accumulates excess syndrome and the deficiency of both QI and blood of malicious decomposed.Clinically, decubital ulcer I degree (erythema phase), decubital ulcer II degree (vesicle phase) and decubital ulcer III degree (ulcerative stage) three phase is divided into according to the forming process of decubital ulcer and the order of severity.Show as in the erythema phase: the compression zone position of whole body shows as local stasis of blood, and skin presents erythema; The vesicle phase shows as: the blister differed in size appears in pressurized position, and skin rubefaction is congested, does not disappear with during finger pressure; Ulcerative stage shows as: ulcer is no more than skin holostrome, and because ulcer basilar part lacks blood supply, in pale asphyxia, granulation edema, flowing water is more than, and severe patient involves fascia and muscle, and traumatic infection is serious.Decubital ulcer is once occur, and cure more difficult, if secondary infection can aggravate disease, severe patient even can cause osteomyelitis, septicemia and hypoproteinemia threat to life.About there are 60,000 people to die from decubital ulcer complication every year according to related documents report, now become No.1 " killer " of typical bed patient.Decubital ulcer not only brings misery to patient, even directly threatens the life of patient, for prolonged illness sickbed patients, further increases their spirit and living burden.
Current clinical treatment decubital ulcer does not also have ideal medicine.Doctor trained in Western medicine surgical operation therapy only for the patient be in a bad way, but has risk and opening is large, and patient suffering greatly, costly, healing is slow.Use antibiotic therapy decubital ulcer to be only effective to traumatic infection, but affect wound healing time.The medicine of existing treatment decubital ulcer among the people is mostly made by oneself personal, and individualized treatment situation is serious, does not have unified treatment by Chinese herbs.
Summary of the invention
Object of the present invention is just to provide a kind of Chinese medicine composition for the treatment of decubital ulcer.
To achieve these goals, the present invention adopts following technical scheme:
Treat a Chinese medicine composition for decubital ulcer, with parts by weight, be made up of following raw material: YUNNAN BAIYAO 8-12 part, Radix Astragali 15-25 part, Rhizoma Chuanxiong 8-12 part, Radix Notoginseng 8-12 part, Cortex Phellodendri 3-8 part, Radix Sanguisorbae 3-8 part, Gypsum Fibrosum Preparatum 15-25 part.
Preferred: a kind of Chinese medicine composition for the treatment of decubital ulcer, with parts by weight, be made up of following raw material: YUNNAN BAIYAO 10 parts, the Radix Astragali 20 parts, Rhizoma Chuanxiong 10 parts, Radix Notoginseng 10 parts, Cortex Phellodendri 6 parts, Radix Sanguisorbae 6 parts, Gypsum Fibrosum Preparatum 20 parts.
China's TCM Culture is of long standing and well established, of extensive knowledge and profound scholarship, and the compatibility of Chinese medicine is particular about mutual reinforcement between, the mutual-assistance, mutual restraint between two drugs, the mutual-detoxication, the mutual inhibition, contrary.Mutual reinforcement between, the medicine fit applications that namely performance effects is similar, can strengthen its original curative effect; The mutual-assistance, in performance effects, namely have the medicine fit applications of certain general character, and based on a kind of medicine, another kind of medicine is auxiliary, can improve the curative effect of principal agent; Mutual restraint between two drugs refers to the mutual inhibitory action between medicine, and the toxicity of medicine or side effect can be cut down by another kind of medicine; The mutual-detoxication, namely a kind of medicine can alleviate or eliminate toxicity or the side effect of another kind of medicine; The mutual inhibition refers to that a kind of medicine can make the original effect of another kind of medicine reduce, and even disappears; Refer to that two kinds of drug combinations can produce or strengthen the compatibility relationship of toxic reaction or side effect on the contrary.Owing to there is different compatibility relationships between different Chinese medicine, therefore when the above Chinese medicine of use two taste, must be allowed a choice, give full play to the compatibility relationship of the mutual reinforcement between mutual-assistance between medicine.The present invention passes through YUNNAN BAIYAO, the Radix Astragali, Rhizoma Chuanxiong, Radix Notoginseng, Cortex Phellodendri, Radix Sanguisorbae, Gypsum Fibrosum Preparatum compatibility, has jointly played the effect for the treatment of decubital ulcer, have obvious potentiation, given full play to the compatibility relationship of the mutual reinforcement between mutual-assistance, effectively can treat decubital ulcer between medicine.Introduce effect of each taste Chinese medicine below respectively and cure mainly disease:
YUNNAN BAIYAO is the famous Chinese patent medicine in Yunnan, is succeeded in developing in 1902 by Yunnan doctor Qu Huanzhang among the people.Good curative effect is had to traumatic injury, wound hemorrhage.YUNNAN BAIYAO is made up of rare medicinal herbs, has effect of removing stasis to stop bleeding, promoting blood circulation and stopping pain, removing toxic substances and promoting subsidence of swelling.Come out over 100 years, YUNNAN BAIYAO is described as " Chinese rarity, traumatology panacea " with its uniqueness, magical effect, is also popular as generation thus, enjoys a high reputation abroad.Can be commercially available.
The Radix Astragali: have another name called Radix Astragali is the dry root of the leguminous plant Radix Astragali or Inner Mongolia Astragalis.Nature and flavor with return through: sweet, tepor.Return lung, spleen channel.Function with cure mainly: tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, promotes the production of body fluid and nourishes blood, row stagnant blood stasis dispelling, expelling pus and toxin by strengthening QI, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, hemiplegia, and arthralgia pain is numb, and carbuncle difficulty is burst, and bursts for a long time and does not hold back.
Rhizoma Chuanxiong: the dry rhizome of samphire Rhizoma Chuanxiong (Ligusticumchuanxiong).Universal umbel, winglike compound leaf, herbaceos perennial.Nature and flavor with return through: pungent, temperature.Return liver, gallbladder, pericardium channel.Function with cure mainly: blood-activating and qi-promoting, wind-expelling pain-stopping.For obstruction of qi in the chest and cardialgia, the twinge of the breast side of body, tumbling and swelling, menoxenia, amenorrhea dysmenorrhea ， mass in the abdomen is suffered from abdominal pain, headache, rheumatic arthralgia.
Radix Notoginseng: nature and flavor with return through sweet, micro-hardship, temperature.Return liver, stomach warp.Function with cure mainly: dissipating blood stasis stops blooding, subduing swelling and relieving pain.For spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling.
Cortex Phellodendri: nature and flavor with return through: bitter, cold.Return kidney, urinary bladder channel.Function with cure mainly: heat clearing and damp drying, pathogenic fire purging except steam, detoxification sore treatment.For damp-heat dysentery, jaundice dark coloured urine, leukorrhagia pudendal pruritus, the puckery pain of pyretic stranguria, beriberi flaccidity of feet with lamenness, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema eczema.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.
Radix Sanguisorbae: nature and flavor with return through: bitter, acid, puckery, be slightly cold.Return liver, large intestine channel.Function with cure mainly: cooling blood for hemostasis, removing toxic substances sore.For having blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, burn due to hot liquid or fire, carbuncle sore tumefacting virus.
Gypsum Fibrosum Preparatum: nature and flavor with return through: sweet, pungent, puckery, cold.Attach to the lung and stomach meridians.Function with cure mainly: removing dampness, granulation promoting, sore, hemostasis.External treatment ulcer being unable to heal, eczema pruritus, burn due to hot liquid or fire, traumatic hemorrhage.
Present invention also offers the application of Chinese medicine composition provided by the invention in preparation treatment decubital ulcer medicine.
Present invention also offers a kind of preparation method of Chinese medicine composition: dry by above-mentioned proportioning raw materials and weigh, mixing, super micron mill crosses 80 order-100 mesh sieves after pulverizing, and ultraviolet-ray sterilizing, mix homogeneously, seals for subsequent use.
Present invention also offers a kind of Chinese medicine composition obtained by preparation method provided by the invention.
Present invention also offers a kind of Chinese medicine preparation, be made up of Chinese medicine composition provided by the invention and pharmaceutically acceptable adjuvant.
As preferably, the dosage form of Chinese medicine preparation is aerosol, powder, unguentum.In Chinese medicine preparation provided by the invention, pharmaceutically acceptable adjuvant is the customary adjuvant in pharmaceutical preparation, and for those skilled in the art think that feasible customary adjuvant is all within protection scope of the present invention, the present invention does not limit at this.
In the present invention, the preparation method of Chinese medicine preparation is conventional preparation method.In the present invention; Chinese medicine composition provided by the invention is mixed with the pharmaceutically acceptable adjuvant needed for different dosage form; utilize routine techniques to make conventional powder, those skilled in the art think that feasible preparation method is all within protection scope of the present invention, and the present invention does not limit at this.
Beneficial effect of the present invention:
Chinese medicine composition of the present invention, can be used for treating patients with decubitus, putrefaction removing, invigorate blood circulation, granulation promoting is effective, without cicatrix more.During treatment, using method is: first rinse wound surface with physiological saline solution again with iodine disinfection local, then Chinese medicine preparation of the present invention being sprinkling upon thickness on wound surface is 2-3 millimeter, and external use sterile gauze covers, and uses 1 every day.Within general 7 ~ 15 days, wound surface can be fully recovered.
The rear sepage of Chinese medicine composition of the present invention reduces, and wound surface is dry, and incrustation is fast, and shorten the time of wound healing, save expense, nursing procedure is easy, time saving and energy saving, has no adverse reaction, and alleviates clinical nursing activity amount, applied widely.
Detailed description of the invention
Embodiment 1
The preparation of Chinese medicine composition
Take YUNNAN BAIYAO 10g, Radix Astragali 20g, Rhizoma Chuanxiong 10g, Radix Notoginseng 10g, Cortex Phellodendri 6g, Radix Sanguisorbae 6g, Gypsum Fibrosum Preparatum 20g, dry, mixing, super micron mill crosses 80 mesh sieves after pulverizing, and ultraviolet-ray sterilizing, mix homogeneously, seals for subsequent use.
Embodiment 2
The preparation of Chinese medicine composition
Take YUNNAN BAIYAO 8g, Radix Astragali 15g, Rhizoma Chuanxiong 8g, Radix Notoginseng 8g, Cortex Phellodendri 3g, Radix Sanguisorbae 3g, Gypsum Fibrosum Preparatum 15g, dry, mixing, super micron mill crosses 100 mesh sieves after pulverizing, and ultraviolet-ray sterilizing, mix homogeneously, seals for subsequent use.
Embodiment 3
The preparation of Chinese medicine composition
Take YUNNAN BAIYAO 12g, Radix Astragali 25g, Rhizoma Chuanxiong 12g, Radix Notoginseng 12g, Cortex Phellodendri 8g, Radix Sanguisorbae 8g, Gypsum Fibrosum Preparatum 25g, dry, mixing, super micron mill crosses 90 mesh sieves after pulverizing, and ultraviolet-ray sterilizing, mix homogeneously, seals for subsequent use.
Experimental example
One, patient data
Two, the criterion of decubital ulcer
I degree: pressurized position skin rubefaction, epidermis is rotten to the corn, oozes out on a small quantity.II degree: skin holostrome ulceration, but subcutaneous tissue not yet involves.III degree: skin ulceration reaches subcutaneous tissue deeply, involves fascia and muscle, but deep layer osseous tissue is not got involved.IV degree: deeply reach osseous tissue, accompanies osteonecrosis and infection simultaneously.
Choose occur decubital ulcer patient 36 example, age 72-98 year, average 87.54 years old.Wherein, man 20 example, female 16 example.Tail sacrum portion 28 example, accounts for 77.7%, and hip 4 example, accounts for 11.1%, and back 1 example, accounts for 2.8%, and ankle and foot 3 example, accounts for 8.3%.
MethodsThe cases enrolled all meets the criterion of decubital ulcer.
Using method: by affected part warm water cleaning, dry, ANER DIAN disinfectant solution is sterilized, and be then sprinkling upon on wound surface by Chinese medicine preparation of the present invention, thickness is 2-3 millimeter, and external use sterile gauze covers, continuous administration 7 ~ 15 days.
Three, efficacy assessment standard
Following efficacy assessment standard is formulated with reference to " disease of tcm Standardization of diagnosis and curative effect ".Recovery from illness: wound surface epithelium covers completely, and cicatrix is solid, observed wound surface through 1 week and does not fester again; Effective: wound surface reduces > 75%, and granulation tissue is fresh, remission; Take a turn for the better: wound surface reduces > 25%, and < 75%, granulation tissue comparatively fresh, symptom is improved; Invalid: though wound surface is comparatively front fresh, reduce < 25%, and granulation tissue growth seldom.
Four, result
Through treatment, 36 routine wounds epitheliums cover completely, and cicatrix is solid, observe wound surface and do not fester again, therefore all meet the standard of recovery from illness through 1 week.
Five, untoward reaction
Over the course for the treatment of tracing observation is carried out for 36 routine patients, does not find obvious untoward reaction.
Model case
Case 1: Lee so-and-so, man, 85 years old, cause " cholelithiasis " row cholecystectomy treatment in 8 years, postoperative discovery choledocholithiasis, abnormal liver function repeatedly, row " ERCP+EST+ bile duct lithotomy " and " the left hepatic duct stenosis bougie of ERCP+, balloon expandable+biliary tract rack implantation "; Suffer from more than 10 years of " cerebral infarction " medical history, more than 2 years of " old myocardial infarction " medical history.Bring into outside institute: the visible 5cm × 6cmII degree pressure ulcer in left sacrum and coccyx bone place, the visible one 2 × 2cmII degree pressure ulcer of left ankle place, the visible one 4 × 2cmII degree pressure ulcer of right ankle place.Liver function biochemistry shows: glutamic oxaloacetic transaminase, GOT: 51U/L, glutamate pyruvate transaminase: 29U/L, glutamy turn phthalein enzyme: 664U/L, alkali phosphatase: 790U/L, albumin: 29.0g/L, globulin: 41.6g/L, potassium: 3.60mmol/l, sodium: 130mmol/L.With the ANER DIAN disinfectant solution sterilization wound surface surrounding skin of Shanghai profit Kanggong department production, with the soft wiping wound surface of physiological saline solution cotton balls and surrounding skin, wait to do, then Chinese medicine preparation of the present invention being sprinkling upon thickness on wound surface is 2-3 millimeter, external use sterile gauze covers, and uses 1 every day.Give nutritional support () simultaneously the next day of albumin 10g once.Give air fluidized bed, timing inflation/deflation, to alleviate the compressing to local surfaces.Observe local circumstance, the 2nd day, decubital ulcer secretions oozed out minimizing, and the 4th day, decubital ulcer was oozed out without secretions, oozes out without secretions, visible granulation tissue.7th day, bedsore wound was fully recovered, the 10th day, cambium and normal surrounding tissue color slightly difference, surperficial smooth non-boundary.
Case 2: Zhao so-and-so, man, 87 years old, patient's " cerebral infarction, parkinson's syndrome, vascular dementia " obnubilation, limbs were stuporous state, agraphia, more than 2 years.Because having " prostatic hyperplasia ", dysuria, more than the 1 year cystostomy that moves ahead, bladder creating-fistula continues indwelling catheter, periodic replacement bladder creating-fistula.Bring into outside institute: a buttocks visible size in left side is about the II phase pressure ulcer of 8cmx6cm, inside has the skin injury of 2x1.5cm, has secretions to ooze out.With the ANER DIAN disinfectant solution sterilization wound surface surrounding skin of Shanghai profit Kanggong department production, sterile scissors cuts off dead bark and black crust, normal saline flushing wound surface, wait to do, then Chinese medicine preparation of the present invention being sprinkling upon thickness on wound surface is 2-3 millimeter, and external use sterile gauze covers, and uses 1 every day.Give nutritional support (hundred general power 500mlqd) simultaneously, give air fluidized bed, timing inflation/deflation, to alleviate the compressing to local surfaces.7 ~ 14 days, bedsore wound was fully recovered.
Case 3: Lee so-and-so, 76 years old, there is cognitive disorder after injected current influenza vaccine before patient 5-6, drowsiness shape in female, that exhales can answer.Reaction is slow, poor memory, language problem.Grow, nutrition is normal, and positive position, haves a medical check-up uncooperative.Move ahead left side TKA for 1 year.The visible size of patient's sacrococcygeal region is about the II phase pressure ulcer of 6cmx4cm, inside has the skin injury of 0.8x0.5cm.With the ANER DIAN disinfectant solution sterilization wound surface surrounding skin of Shanghai profit Kanggong department production, with the soft wiping wound surface of physiological saline solution cotton balls and surrounding skin, wait to do, then Chinese medicine preparation of the present invention being sprinkling upon thickness on wound surface is 2--3 millimeter, external use sterile gauze covers, and uses 1 every day.Give air fluidized bed, timing inflation/deflation, to alleviate the compressing to local surfaces simultaneously.Strengthen nutrition, give rational diet according to the state of an illness.5 ~ 7 days, bedsore wound was fully recovered.
Although above-mentioned, the specific embodiment of the present invention is described; but not limiting the scope of the invention; one of ordinary skill in the art should be understood that; on the basis of technical scheme of the present invention, those skilled in the art do not need to pay various amendment or distortion that creative work can make still within protection scope of the present invention.
Claims (7)
1. treat a Chinese medicine composition for decubital ulcer, it is characterized in that: with parts by weight, be made up of following raw material: YUNNAN BAIYAO 8-12 part, Radix Astragali 15-25 part, Rhizoma Chuanxiong 8-12 part, Radix Notoginseng 8-12 part, Cortex Phellodendri 3-8 part, Radix Sanguisorbae 3-8 part, Gypsum Fibrosum Preparatum 15-25 part.
2. Chinese medicine composition as claimed in claim 1, is characterized in that: with parts by weight, is made up of following raw material: YUNNAN BAIYAO 10 parts, the Radix Astragali 20 parts, Rhizoma Chuanxiong 10 parts, Radix Notoginseng 10 parts, Cortex Phellodendri 6 parts, Radix Sanguisorbae 6 parts, Gypsum Fibrosum Preparatum 20 parts.
3. the application of Chinese medicine composition as claimed in claim 1 or 2 in preparation treatment decubital ulcer medicine.
4. a preparation method for Chinese medicine composition, is characterized in that: with parts by weight, raw material is by YUNNAN BAIYAO 8-12 part, Radix Astragali 15-25 part, Rhizoma Chuanxiong 8-12 part, Radix Notoginseng 8-12 part, Cortex Phellodendri 3-8 part, Radix Sanguisorbae 3-8 part, Gypsum Fibrosum Preparatum 15-25 part forms, and mixing after drying, crosses 80 order-100 mesh sieves after pulverizing, ultraviolet-ray sterilizing, mix homogeneously and get final product.
5. the Chinese medicine composition that preparation method as claimed in claim 4 is obtained.
6. a Chinese medicine preparation, is characterized in that: be made up of the Chinese medicine composition as described in claim 1,2 or 4 and pharmaceutically acceptable adjuvant.
7. Chinese medicine preparation as claimed in claim 6, is characterized in that: the dosage form of described Chinese medicine preparation is aerosol, powder, unguentum.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105687925A (en) * | 2016-03-09 | 2016-06-22 | 山东省千佛山医院 | Traditional Chinese medicine composition for treating elderly female bedsores and preparation method of traditional Chinese medicine composition |
| CN106511676A (en) * | 2016-11-15 | 2017-03-22 | 王同新 | Traditional Chinese medicine composition for treating bedsore in clinical nursing |
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| CN1426786A (en) * | 2001-12-20 | 2003-07-02 | 肖永良 | Ointment made of Chinese medicinal herbs for treating bedsore difficult to cure |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1426786A (en) * | 2001-12-20 | 2003-07-02 | 肖永良 | Ointment made of Chinese medicinal herbs for treating bedsore difficult to cure |
Non-Patent Citations (3)
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| 刘孔锦: "复方三七酊可消肿止痛", 《中原医刊》 * |
| 高月平等: "褥疮的中医药治疗现状", 《中华中医药杂志》 * |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105687925A (en) * | 2016-03-09 | 2016-06-22 | 山东省千佛山医院 | Traditional Chinese medicine composition for treating elderly female bedsores and preparation method of traditional Chinese medicine composition |
| CN106511676A (en) * | 2016-11-15 | 2017-03-22 | 王同新 | Traditional Chinese medicine composition for treating bedsore in clinical nursing |
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