CN1232499A - 人生长基因和身材矮小基因区 - Google Patents

人生长基因和身材矮小基因区 Download PDF

Info

Publication number
CN1232499A
CN1232499A CN97198471A CN97198471A CN1232499A CN 1232499 A CN1232499 A CN 1232499A CN 97198471 A CN97198471 A CN 97198471A CN 97198471 A CN97198471 A CN 97198471A CN 1232499 A CN1232499 A CN 1232499A
Authority
CN
China
Prior art keywords
seq
dna
sequence
gene
shox
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN97198471A
Other languages
English (en)
Chinese (zh)
Inventor
居德伦·拉波尔德－赫尔布兰德
埃尔科莱·拉奥
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gudrun RAPPOLD HOERBRAND
Original Assignee
Gudrun RAPPOLD HOERBRAND
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gudrun RAPPOLD HOERBRAND filed Critical Gudrun RAPPOLD HOERBRAND
Publication of CN1232499A publication Critical patent/CN1232499A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Obesity (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
CN97198471A 1996-10-01 1997-09-29 人生长基因和身材矮小基因区 Pending CN1232499A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US2763396P 1996-10-01 1996-10-01
US60/027,633 1996-10-01
EP97100583.0 1997-01-16
EP97100583 1997-01-16

Publications (1)

Publication Number Publication Date
CN1232499A true CN1232499A (zh) 1999-10-20

Family

ID=26145174

Family Applications (1)

Application Number Title Priority Date Filing Date
CN97198471A Pending CN1232499A (zh) 1996-10-01 1997-09-29 人生长基因和身材矮小基因区

Country Status (20)

Country Link
US (2) US7252974B2 (enExample)
EP (2) EP0946721B1 (enExample)
JP (2) JP2000515025A (enExample)
KR (1) KR20000048838A (enExample)
CN (1) CN1232499A (enExample)
AT (1) ATE230026T1 (enExample)
AU (1) AU744188C (enExample)
BR (1) BR9712185A (enExample)
CA (2) CA2267097A1 (enExample)
CZ (1) CZ297640B6 (enExample)
DE (1) DE69718052T2 (enExample)
DK (1) DK0946721T3 (enExample)
ES (1) ES2188992T3 (enExample)
HU (1) HU225131B1 (enExample)
IL (1) IL129015A0 (enExample)
NO (1) NO991554L (enExample)
NZ (1) NZ334970A (enExample)
PL (1) PL194248B1 (enExample)
SI (1) SI0946721T1 (enExample)
WO (1) WO1998014568A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000056765A1 (en) * 1999-03-19 2000-09-28 Human Genome Sciences, Inc. 48 human secreted proteins
AU3913100A (en) * 1999-03-26 2000-10-16 Human Genome Sciences, Inc. 50 human secreted proteins
US7736654B2 (en) 2001-04-10 2010-06-15 Agensys, Inc. Nucleic acids and corresponding proteins useful in the detection and treatment of various cancers
US7927597B2 (en) 2001-04-10 2011-04-19 Agensys, Inc. Methods to inhibit cell growth
WO2003038087A1 (en) 2001-10-04 2003-05-08 Kansai Technology Licensing Organization Co., Ltd. DR5 GENE PROMOTER AND Siah-1 GENE PROMOTER
EP1583554A2 (en) * 2003-01-13 2005-10-12 Gudrun Rappold-Hoerbrand Use of natriuretic peptides for the treatment of stature disorders related to the shox gene
ES2533767T3 (es) 2005-04-15 2015-04-15 Epigenomics Ag Métodos para el análisis de trastornos proliferativos celulares
US7382944B1 (en) 2006-07-14 2008-06-03 The United States Of America As Represented By The Administration Of The National Aeronautics And Space Administration Protective coating and hyperthermal atomic oxygen texturing of optical fibers used for blood glucose monitoring
ES2384071T3 (es) * 2007-01-19 2012-06-29 Epigenomics Ag Métodos y ácidos nucleicos para análisis de trastornos proliferativos celulares
WO2014182595A1 (en) * 2013-05-06 2014-11-13 Mikko Sofia Diagnostic test for skeletal atavism in horses

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3445933A1 (de) * 1984-12-17 1986-06-19 Röhm GmbH, 6100 Darmstadt Arzneimittel mit diuretischer wirksamkeit
US4983511A (en) * 1989-01-09 1991-01-08 Olin Corporation Method and kit for detecting live microorganisms in chlorine- or bromine-treated water

Also Published As

Publication number Publication date
IL129015A0 (en) 2000-02-17
EP0946721A1 (en) 1999-10-06
PL194248B1 (pl) 2007-05-31
HU225131B1 (en) 2006-06-28
BR9712185A (pt) 1999-08-31
CA2267097A1 (en) 1998-04-09
DE69718052T2 (de) 2003-07-31
NO991554L (no) 1999-05-14
ES2188992T3 (es) 2003-07-01
JP2000515025A (ja) 2000-11-14
JP2004201692A (ja) 2004-07-22
PL332568A1 (en) 1999-09-27
US20090111744A1 (en) 2009-04-30
WO1998014568A1 (en) 1998-04-09
HUP9904175A3 (en) 2002-01-28
DK0946721T3 (da) 2003-04-14
NZ334970A (en) 2000-12-22
EP1260228A3 (en) 2003-03-05
NO991554D0 (no) 1999-03-30
AU744188B2 (en) 2002-02-14
US20030059805A1 (en) 2003-03-27
AU4625297A (en) 1998-04-24
CZ297640B6 (cs) 2007-02-21
KR20000048838A (ko) 2000-07-25
CZ96699A3 (cs) 1999-08-11
HUP9904175A2 (hu) 2000-04-28
EP0946721B1 (en) 2002-12-18
EP1260228A2 (en) 2002-11-27
AU744188C (en) 2003-07-24
CA2647169A1 (en) 1998-04-09
ATE230026T1 (de) 2003-01-15
DE69718052D1 (de) 2003-01-30
US7252974B2 (en) 2007-08-07
SI0946721T1 (en) 2003-06-30

Similar Documents

Publication Publication Date Title
CN1159829A (zh) 17q连锁的乳房癌和卵巢癌易患性基因
AU2016325030A1 (en) Novel biomarkers and methods of treating cancer
CN1270637A (zh) 新的衰老因子基因p23的分离
CN1232499A (zh) 人生长基因和身材矮小基因区
AU2017302611B2 (en) GPR156 variants and uses thereof
US6262334B1 (en) Human genes and expression products: II
JP2001245666A (ja) 新規ポリペプチド
CN1777676A (zh) 与精神分裂症相关的电压门控离子通道基因及蛋白质
CA2348657C (fr) Clonage, expression et caracterisation du gene spg4 responsable de la forme la plus frequente de paraplegie spastique autosomique dominante
HK1023146A (en) Human growth gene and short stature gene region
KR20230124973A (ko) 인간화 tslp 유전자, 인간화 tslp 수용체 유전자, 및/또는인간화 il7ra 유전자를 갖는 비인간 동물
CN1780910A (zh) 对与家族性高胆固醇血症有关的分离的低密度脂蛋白受体(ldl－r)的基因序列中的突变进行检测的方法和装置
US6627745B1 (en) Pyrin gene and mutants thereof, which cause familial Mediterranean fever
Class et al. Patent application title: Human Growth Gene and Short Stature Gene Region Inventors: Gudrun Rappold-Hoerbrand (Heidelberg, DE) Ercole Rao (Riedstadt, DE)
CN1129001A (zh) 编码胰岛素受体底物1的突变dna
CN1246457C (zh) 人tsc403基因和人ing1l基因
CN1222616C (zh) 具有抑癌功能的新的人蛋白及其编码序列
CN1199995C (zh) 具有抑癌功能的新的人蛋白及其编码序列
CN1155616C (zh) 具有促进癌细胞生长功能的新的人蛋白及其编码序列
CN1199997C (zh) 具有促进小鼠nih/3t3细胞转化功能的新的人蛋白及其编码序列
US20030104521A1 (en) Disease associated gene
US20030170683A1 (en) Formin-2 nucleic acids and polypeptides and uses thereof
CN1177047C (zh) 编码具有抑癌功能的人蛋白的多核苷酸
MXPA99002809A (en) Human growth gene and short stature gene region
CN1861805A (zh) 甘油三磷酸脱氢酶基因与原发性高血压的相关性

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication
REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1023146

Country of ref document: HK