DE69718052D1 - Menschliches wachstumsgen und minderwuchse gen bereich - Google Patents
Menschliches wachstumsgen und minderwuchse gen bereichInfo
- Publication number
- DE69718052D1 DE69718052D1 DE69718052T DE69718052T DE69718052D1 DE 69718052 D1 DE69718052 D1 DE 69718052D1 DE 69718052 T DE69718052 T DE 69718052T DE 69718052 T DE69718052 T DE 69718052T DE 69718052 D1 DE69718052 D1 DE 69718052D1
- Authority
- DE
- Germany
- Prior art keywords
- sequence
- shox
- given
- growth
- human growth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 108700025071 Short Stature Homeobox Proteins 0.000 abstract 3
- 102100029992 Short stature homeobox protein Human genes 0.000 abstract 3
- 239000012634 fragment Substances 0.000 abstract 3
- 108020004414 DNA Proteins 0.000 abstract 2
- 102000053602 DNA Human genes 0.000 abstract 2
- 101100477520 Homo sapiens SHOX gene Proteins 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 102000001420 Homeobox domains Human genes 0.000 abstract 1
- 108050009606 Homeobox domains Proteins 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 101150012871 SHOX gene Proteins 0.000 abstract 1
- 208000020221 Short stature Diseases 0.000 abstract 1
- 108091023040 Transcription factor Proteins 0.000 abstract 1
- 102000040945 Transcription factor Human genes 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 239000002299 complementary DNA Substances 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2763396P | 1996-10-01 | 1996-10-01 | |
EP97100583 | 1997-01-16 | ||
PCT/EP1997/005355 WO1998014568A1 (en) | 1996-10-01 | 1997-09-29 | Human growth gene and short stature gene region |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69718052D1 true DE69718052D1 (de) | 2003-01-30 |
DE69718052T2 DE69718052T2 (de) | 2003-07-31 |
Family
ID=26145174
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69718052T Expired - Lifetime DE69718052T2 (de) | 1996-10-01 | 1997-09-29 | Menschliches wachstumsgen und minderwuchse gen bereich |
Country Status (20)
Country | Link |
---|---|
US (2) | US7252974B2 (de) |
EP (2) | EP0946721B1 (de) |
JP (2) | JP2000515025A (de) |
KR (1) | KR20000048838A (de) |
CN (1) | CN1232499A (de) |
AT (1) | ATE230026T1 (de) |
AU (1) | AU744188C (de) |
BR (1) | BR9712185A (de) |
CA (2) | CA2647169A1 (de) |
CZ (1) | CZ297640B6 (de) |
DE (1) | DE69718052T2 (de) |
DK (1) | DK0946721T3 (de) |
ES (1) | ES2188992T3 (de) |
HU (1) | HU225131B1 (de) |
IL (1) | IL129015A0 (de) |
NO (1) | NO991554L (de) |
NZ (1) | NZ334970A (de) |
PL (1) | PL194248B1 (de) |
SI (1) | SI0946721T1 (de) |
WO (1) | WO1998014568A1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000056765A1 (en) * | 1999-03-19 | 2000-09-28 | Human Genome Sciences, Inc. | 48 human secreted proteins |
CA2368469A1 (en) * | 1999-03-26 | 2000-10-05 | Craig A. Rosen | 50 human secreted proteins |
US7927597B2 (en) | 2001-04-10 | 2011-04-19 | Agensys, Inc. | Methods to inhibit cell growth |
AU2002318112B2 (en) | 2001-04-10 | 2007-12-06 | Agensys, Inc. | Nucleic acids and corresponding proteins useful in the detection and treatment of various cancers |
WO2003038087A1 (fr) | 2001-10-04 | 2003-05-08 | Kansai Technology Licensing Organization Co., Ltd. | Promoteur du gene dr5 et promoteur du gene siah-1 |
US20060172929A1 (en) * | 2003-01-13 | 2006-08-03 | Gudrun Rappold-Hoerbrand | Use of natriuretic peptides for the treatment of stature disorders related to the shox gene |
KR20080011287A (ko) | 2005-04-15 | 2008-02-01 | 에피제노믹스 아게 | 세포 증식 질환을 분석하기 위한 방법 및 핵산 |
US7382944B1 (en) | 2006-07-14 | 2008-06-03 | The United States Of America As Represented By The Administration Of The National Aeronautics And Space Administration | Protective coating and hyperthermal atomic oxygen texturing of optical fibers used for blood glucose monitoring |
EP2258871B1 (de) * | 2007-01-19 | 2014-05-14 | Epigenomics AG | Verfahren und Nukleinsäuren zur Analyse von zellproliferativen Krankheiten |
WO2014182595A1 (en) | 2013-05-06 | 2014-11-13 | Mikko Sofia | Diagnostic test for skeletal atavism in horses |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3445933A1 (de) * | 1984-12-17 | 1986-06-19 | Röhm GmbH, 6100 Darmstadt | Arzneimittel mit diuretischer wirksamkeit |
US4983511A (en) * | 1989-01-09 | 1991-01-08 | Olin Corporation | Method and kit for detecting live microorganisms in chlorine- or bromine-treated water |
-
1997
- 1997-09-29 BR BR9712185-1A patent/BR9712185A/pt unknown
- 1997-09-29 DE DE69718052T patent/DE69718052T2/de not_active Expired - Lifetime
- 1997-09-29 AT AT97944906T patent/ATE230026T1/de active
- 1997-09-29 SI SI9730485T patent/SI0946721T1/xx unknown
- 1997-09-29 CA CA002647169A patent/CA2647169A1/en not_active Abandoned
- 1997-09-29 CN CN97198471A patent/CN1232499A/zh active Pending
- 1997-09-29 KR KR1019990702836A patent/KR20000048838A/ko not_active Application Discontinuation
- 1997-09-29 CA CA002267097A patent/CA2267097A1/en not_active Abandoned
- 1997-09-29 JP JP10516222A patent/JP2000515025A/ja active Pending
- 1997-09-29 DK DK97944906T patent/DK0946721T3/da active
- 1997-09-29 EP EP97944906A patent/EP0946721B1/de not_active Expired - Lifetime
- 1997-09-29 IL IL12901597A patent/IL129015A0/xx unknown
- 1997-09-29 NZ NZ334970A patent/NZ334970A/xx unknown
- 1997-09-29 ES ES97944906T patent/ES2188992T3/es not_active Expired - Lifetime
- 1997-09-29 PL PL97332568A patent/PL194248B1/pl not_active IP Right Cessation
- 1997-09-29 AU AU46252/97A patent/AU744188C/en not_active Ceased
- 1997-09-29 HU HU9904175A patent/HU225131B1/hu not_active IP Right Cessation
- 1997-09-29 CZ CZ0096699A patent/CZ297640B6/cs not_active IP Right Cessation
- 1997-09-29 EP EP02011329A patent/EP1260228A3/de not_active Withdrawn
- 1997-09-29 WO PCT/EP1997/005355 patent/WO1998014568A1/en active IP Right Grant
-
1999
- 1999-03-30 NO NO991554A patent/NO991554L/no not_active Application Discontinuation
-
2002
- 2002-05-31 US US10/158,160 patent/US7252974B2/en not_active Expired - Fee Related
-
2004
- 2004-03-02 JP JP2004058276A patent/JP2004201692A/ja active Pending
-
2007
- 2007-05-15 US US11/748,769 patent/US20090111744A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2647169A1 (en) | 1998-04-09 |
NO991554L (no) | 1999-05-14 |
ATE230026T1 (de) | 2003-01-15 |
HUP9904175A3 (en) | 2002-01-28 |
DE69718052T2 (de) | 2003-07-31 |
NO991554D0 (no) | 1999-03-30 |
CA2267097A1 (en) | 1998-04-09 |
HU225131B1 (en) | 2006-06-28 |
JP2000515025A (ja) | 2000-11-14 |
ES2188992T3 (es) | 2003-07-01 |
IL129015A0 (en) | 2000-02-17 |
AU744188C (en) | 2003-07-24 |
CZ96699A3 (cs) | 1999-08-11 |
US7252974B2 (en) | 2007-08-07 |
HUP9904175A2 (hu) | 2000-04-28 |
US20030059805A1 (en) | 2003-03-27 |
PL332568A1 (en) | 1999-09-27 |
DK0946721T3 (da) | 2003-04-14 |
JP2004201692A (ja) | 2004-07-22 |
EP1260228A3 (de) | 2003-03-05 |
CN1232499A (zh) | 1999-10-20 |
US20090111744A1 (en) | 2009-04-30 |
WO1998014568A1 (en) | 1998-04-09 |
CZ297640B6 (cs) | 2007-02-21 |
KR20000048838A (ko) | 2000-07-25 |
AU4625297A (en) | 1998-04-24 |
EP1260228A2 (de) | 2002-11-27 |
SI0946721T1 (en) | 2003-06-30 |
AU744188B2 (en) | 2002-02-14 |
BR9712185A (pt) | 1999-08-31 |
PL194248B1 (pl) | 2007-05-31 |
EP0946721B1 (de) | 2002-12-18 |
EP0946721A1 (de) | 1999-10-06 |
NZ334970A (en) | 2000-12-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |