CN1228994A - 刺猬蛋白的药物组合物及其应用 - Google Patents

刺猬蛋白的药物组合物及其应用 Download PDF

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Publication number
CN1228994A
CN1228994A CN99101764A CN99101764A CN1228994A CN 1228994 A CN1228994 A CN 1228994A CN 99101764 A CN99101764 A CN 99101764A CN 99101764 A CN99101764 A CN 99101764A CN 1228994 A CN1228994 A CN 1228994A
Authority
CN
China
Prior art keywords
carrier
hedgelog protein
protein
hedgelog
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN99101764A
Other languages
English (en)
Chinese (zh)
Inventor
K·兰格
A·帕普迪米卓奥
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of CN1228994A publication Critical patent/CN1228994A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN99101764A 1998-02-04 1999-02-04 刺猬蛋白的药物组合物及其应用 Pending CN1228994A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP98101893 1998-02-04
EP98101893.0 1998-02-04
EP98104416 1998-03-12
EP98104416.7 1998-03-12

Publications (1)

Publication Number Publication Date
CN1228994A true CN1228994A (zh) 1999-09-22

Family

ID=26149005

Family Applications (1)

Application Number Title Priority Date Filing Date
CN99101764A Pending CN1228994A (zh) 1998-02-04 1999-02-04 刺猬蛋白的药物组合物及其应用

Country Status (14)

Country Link
JP (1) JP3092706B2 (no)
KR (2) KR19990072406A (no)
CN (1) CN1228994A (no)
AT (1) ATE331533T1 (no)
AU (1) AU713568B2 (no)
CA (1) CA2260423C (no)
CZ (1) CZ33799A3 (no)
DE (1) DE69932113T2 (no)
HU (1) HUP9900251A3 (no)
IL (1) IL128329A (no)
MA (1) MA26602A1 (no)
NO (1) NO990471L (no)
NZ (1) NZ334065A (no)
SG (1) SG66504A1 (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW570805B (en) 1998-09-01 2004-01-11 Hoffmann La Roche Water-soluble pharmaceutical composition in an ionic complex
KR100452752B1 (ko) * 2000-04-18 2004-10-12 주식회사 펩트론 단백질 함유 서방성 제제를 제조하는 방법 및 그 제제
KR101705323B1 (ko) * 2010-03-23 2017-02-13 코웨이 주식회사 역삼투막 방식의 정수기
CN102174794B (zh) * 2011-03-07 2012-08-15 江苏科技大学 一种六点支撑架桥作业平台自动调平系统及方法
KR102176832B1 (ko) * 2017-11-29 2020-11-10 주식회사 파이안바이오테크놀로지 헤지호그 단백질 및 생체 적합성 물질을 포함하는 미세 입자 및 이를 포함하는 탈모 예방 또는 치료용 조성물

Also Published As

Publication number Publication date
CA2260423A1 (en) 1999-08-04
HUP9900251A3 (en) 2001-01-29
NO990471D0 (no) 1999-02-01
CZ33799A3 (cs) 1999-08-11
AU713568B2 (en) 1999-12-02
IL128329A0 (en) 2000-01-31
HU9900251D0 (en) 1999-03-29
ATE331533T1 (de) 2006-07-15
AU1542699A (en) 1999-08-26
KR100311565B1 (ko) 2001-11-02
IL128329A (en) 2005-08-31
CA2260423C (en) 2006-06-20
HUP9900251A2 (hu) 1999-09-28
NZ334065A (en) 2000-06-23
SG66504A1 (en) 2000-07-18
JP3092706B2 (ja) 2000-09-25
JP2000119193A (ja) 2000-04-25
DE69932113T2 (de) 2007-01-25
MA26602A1 (fr) 2004-12-20
NO990471L (no) 1999-08-05
KR19990072406A (ko) 1999-09-27
KR19990072423A (ko) 1999-09-27
DE69932113D1 (de) 2006-08-10

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Legal Events

Date Code Title Description
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C06 Publication
PB01 Publication
C53 Correction of patent of invention or patent application
CB02 Change of applicant information

Applicant after: Roche Diagnosis GmbH

Applicant before: Boehringer Mannheim GmbH

COR Change of bibliographic data

Free format text: CORRECT: APPLICANT; FROM: BOEHRINGER MANNHEIM GMBH TO: ROCHE DIAGNOSTICS GMBH

C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication