CN1225269C - Medicine for treating prospoalgia - Google Patents
Medicine for treating prospoalgia Download PDFInfo
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- CN1225269C CN1225269C CN 03126276 CN03126276A CN1225269C CN 1225269 C CN1225269 C CN 1225269C CN 03126276 CN03126276 CN 03126276 CN 03126276 A CN03126276 A CN 03126276A CN 1225269 C CN1225269 C CN 1225269C
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Abstract
The present invention relates to Chinese patent medicine, particularly to medicine for treating trigeminal neuralgia. The present invention contains the components of the following parts by weight: 30 to 60 parts of red sage root, 50 to 100 parts of white peony alba, 15 to 30 parts of hemlock parsley, 10 to 20 parts of liquoric root and 30 to 60 parts of milkvetch root, wherein the white peony alba and the liquoric root are sliced according to the parts by weight and then are pulverized into 120 meshes of medicine powder after being dried in the sun or baked. The red sage root, the hemlock parsley and the milkvetch root are mixed and sliced according to the parts by weight, and 5 to 7 times of water is added to mixtures which are boiled in water and concentrated into medical liquid with 1 to 1.5 times of parts by weight of dry medicine; the medicine powder of the white peony alba and the liquoric root powder is added and is thoroughly and uniformly mixed with the medical liquid, and then products are made into capsules after being baked and pulverized. The effect of the present invention for treating trigeminal neuralgia can take rapidly, and the present invention can usually take effect in the day of taking the medicine; the curative effect and the curing performance of the present invention are good without the relapse of trigeminal neuralgia. In addition, the medicine of the present invention has the advantages of wide source, simple processing and no toxic or side effects, and therefore, the medicine can be taken securely.
Description
One. technical field: the present invention relates to a kind of Chinese patent medicine, particularly relate to the prosopalgic medicine of a kind of treatment.
Two. background technology: well-known, the someone says frequent headache or migraine at ordinary times, the said trigeminal neuralgia of doctor trained in Western medicine that Here it is.Trigeminal neuralgia is the commonly encountered diseases in human many diseases, and paroxysmal having an intense pain often appears in chronic disease, the form and the character of pain differ, have as the electric shock, have as pinprick, have as lancinating, the patient suffering is hard to bear, has no way out, and trigeminal neuralgia is a kind of performance of neurapraxia, this disease is shown effect repeatedly, be difficult to cure, cause very big misery, have a strong impact on patient's study, work and life to the patient.The trigeminal neuralgia cause is more, the headache that has nervus vasculairs to cause, and the tension headache that has nervous system to cause, the headache that has rheumatism to cause, the trigeminal neuralgia that has hypertension to cause also has cerebrovascular, or the trigeminal neuralgia that causes of the sequela of cerebral trauma.
In recent years, along with development of science and technology, majority think that trigeminal neuralgia is because nervi trigeminus is caused by contiguous perstriction, cause the fiber extruding by the trifacial compressing of blood vessel, demyelinating becomes, dummy shaft is dashed forward formation and " short circuit " is taken place, import nervus centralis into, and the nervus centralis efferent impulse spread also can become afferent impulse by " short circuit ", so reaches certain " summation " very soon, thereby causes for a moment and have an intense pain, till the neuron that participates in is tired out, through intermittence regular hour, repeat said process again, pain is shown effect repeatedly.
The western medical treatment trigeminal neuralgia is mainly with carbamazepine, and phenytoin sodium is the Western medicine analgesics therapy of representative, or the closed injection therapy, or radiofrequency therapy, or electrotherapy etc., its therapeutic effect is an alleviating pain, pain relieving, calmness, its curative effect is not really desirable, the relapse rate height, recurrence time is shorter and shorter at interval, also has operative therapy, though can improve curative effect, costly, and sometimes if other nerves of damage, cause tangible sequela easily, as facial paralysis.The general operative therapy beyond affordability of patient.Western medicine can only relief of symptoms, can not effect a radical cure, and stronger to the medicine dependency, strengthens with dose, and the patient is drowsiness, dizziness, and hypomnesis, walking is unstable, and heart beating and brothers tremble drug side effect such as fiber crops and produce serious involved Liver and kidney gradually.
The traditional Chinese medical science is thought to trigeminal neuralgia (i.e. headache, migraine): hinder the retardance meridians because of QI and blood stagnates; Or, causing QI and blood disorderly contrary because of all diseases of internal injury, stasis of blood resistance meridians, brain are become homeless to support and all can be caused headache.Headache, it is depressed that migraine is divided into empty positive rising (being Liver and kidney void), deficiency of QI in middle-JIAO and breast substantially, the cold-damp yang collaterals, the former sore spot mostly is a place on the nervi trigeminus, it is one-sided temple jumping pain, latter's sore spot mostly is a trifacial following part, and the prosopalgic superiority of treatment by Chinese herbs is a few side effects, and cure rate is higher.The prosopalgic medicine of treatment of existing market circulation is less, and majority is that out-patient department or outpatient service training are more through proved recipe or side handed down from one's ancestors.As CN1046093C, ZL94103392.9, name is called the prosopalgic Chinese medicine of a kind of treatment.This medicine is by the Radix Astragali, Radix Adenophorae (Radix Glehniae), and Radix Glycyrrhizae, Radix Platycodonis, Rhizoma Cimicifugae, Radix Puerariae, Radix Rehmanniae Preparata, Radix Bupleuri, Scolopendra, 37 flavor Chinese herbal medicine such as Pheretima are formed according to a certain ratio, and cure rate is higher, reaches 92%.But it is more, too bad that this Chinese medicine preparation is introduced medicine, is regardless of primary and secondary.To treat any headache more effective actually, has no way of understanding.CN1052158C, ZL94112730.3, name is called a kind of pure Chinese medicine headache trident and looses and preparation method thereof.This medicine discloses with Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Scorpio, Herba Aristolochiae Mollissimae, and Rhizoma Typhonii, Bombyx Batryticatus, Fructus Viticis, Herba Schizonepetae, Herba Asari, Poria, Radix Glycyrrhizae is made powder with processing technique by a certain percentage.It is introduced effective percentage 100%, cure rate 96%, curative effect is better.But need join hot yellow wine when taking medicine, cumbersome.
Three. summary of the invention:
Purpose of the present invention: overcome the deficiency of known technology, through screening for many years, prescription is developed the prosopalgic medicine of a kind of treatment easy to use meticulously.
Technical solution of the present invention:
The prosopalgic medicine of a kind of treatment is made by following bulk drugs, 30～60 parts of Radix Salviae Miltiorrhizaes, 50～100 parts of the Radix Paeoniae Albas, 15～30 parts of Rhizoma Chuanxiongs, 10～20 parts in Radix Glycyrrhizae, 30～60 parts of the Radixs Astragali.
Described medicine is made by following bulk drugs, 50～60 parts of Radix Salviae Miltiorrhizaes, 70～95 parts of the Radix Paeoniae Albas, 20～25 parts of Rhizoma Chuanxiongs, 15～18 parts in Radix Glycyrrhizae, 45～55 parts of the Radixs Astragali.
Above the preparation method of described medicine, with Radix Paeoniae Alba peeling, head, tail and fibrous root, clean mud drops in the boiling water and boiled 5～10 minutes, pull out and dry or dry, section, the clean mud of Radix Glycyrrhizae, dry, section is got part with Radix Paeoniae Alba sheet and Radix Glycyrrhizae tabellae by proportioning then, pulverizing is 120 purpose powder, and fibrous root is removed in Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong remove impurity, clean mud dries section, and the Radix Astragali is saturating with water infiltration, section is dried or dried, and is stand-by.
The dried tablet of Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, the Radix Astragali is got a part mixing by proportioning, add 5～7 times of decocting in water, when boiling into the concentrated medicament of 1～1.5 times of dried medicine weight portion, stop to heat, the Radix Paeoniae Alba and Radix Glycyrrhizae medicated powder are put into this concentrated medicament, fully mix the back oven dry thoroughly, pulverizing is 120 purpose medicated powder.
Pharmaceutical dosage form of the present invention is a powder, or capsule, or pill, or injection.
Beneficial effect of the present invention:
1. the present invention treats the trigeminal neuralgia instant effect, and took medicine the general same day, and took effect the same day.
Patient's reflection that many prescriptions on individual diagnosis are cured, in the past owing to trigeminal neuralgia causes pain unbearably, take powder of the present invention or capsule after, took medicine the same day, pain alleviates to some extent.Sleep constantly improves in the drug administration process, and the state of an illness progressively alleviates.One turns round and look at surname patient, woman, 62 years old, suffer from the trigeminal neuralgia more than ten years, often pain is eaten bad unbearably, not sleep well, seek medical advice repeatedly to Kaifeng, Zhengzhou hospital of a few institute, did the acupuncture point block treatment, lose effect, after the great majority treatment, interim pain relieving, later recurrence again, last lower tooth all pulls out light, still treats badly, has lost the confidence of treatment.Take medicine of the present invention March calendar year 2001, take every day three times, each 5 capsules, the same day, pain relief was taken medicine ten days, and the state of an illness is clearly better, and the patient is full of confidence to treating, with doctor's close fit, through curing (15 days course of treatment) two courses of treatment.The spy feels very grateful to the treatment doctor.
2. curative effect of medication of the present invention healing property is good, does not recur.
Medicine of the present invention has special efficacy to the trigeminal neuralgia that the treatment cardiovascular and cerebrovascular disease causes.In recent years, treatment trigeminal neuralgia case 119 examples, wherein male's 45 examples, women's 74 examples, the age is cured 84 examples all more than 45 years old, account for 70.59% (standard is: cure and afterwards do not recur more than 1 year, claim to cure), produce effects 24 examples, (the pain number of times obviously reduces to account for 20.17%, pain degree obviously reduces, and claims produce effects), effective 11 examples, account for 9.24% (the pain number of times reduces, and degree alleviates title effectively).The trigeminal neuralgia that the overwhelming majority causes for cardiovascular and cerebrovascular disease in curing the patient.Cure the patient and generally need for taking medicine conveniently, make capsule through 1,2 course of treatment, every capsule is adorned 0.4～0.5 gram medicated powder, takes 4～5 at every turn, takes three times in one day.
3. medicine medicine of the present invention source is extensive, and processing is simple, has no side effect, and can relievedly take.
Main medicine is a Radix Salviae Miltiorrhizae in the medicine of the present invention, and it contains Tanshinone I, II, and III also contains iso tanshinone I, cryptotanshinone, dihydroisotanshinones etc. also contain danshensu, protocatechualdehyde, vitamin E, Sitosterolum, hydroxyl tanshinone, erysipelas acid methyl ester, methylene tanshinquinone, danshenxinkun etc.(1) Radix Salviae Miltiorrhizae energy coronary artery dilator increases coronary flow, improves cardiac function, dwindles the myocardial infarction scope.(2) can expand peripheral blood vessel, improve peripheral circulation, improve hypoxia-bearing capability at high pressure or low pressure lower body.(3) nervous system there is calm and stable effect.Have the blood stasis removing pain relieving, promoting blood circulation to restore menstrual flow, pain and dysphoria and insomnia effect are removed in the relieving restlessness that clears away heart-fire.Strengthening the dosage of Radix Salviae Miltiorrhizae, is the characteristic of medicine of the present invention.Another main medicine is the Radix Paeoniae Alba, and it is the Radix Paeoniae peeling, removes bud, removes rice shoot, and decocting in water is pulled out and dried.It contains paeoniflorin, Sitosterolum, and tannin, a small amount of volatile oil, benzoic acid also contains the triterpenoid compound of four kinds of unknown structure, and its Radix Paeoniae glycoside has tranquillizing and allaying excitement, and pain relieving relaxes muscular tone.Make blood circulation normal, and inhibited to the central nervous system.Cure mainly the dizziness that causes by blood-deficiency leading to hyperactivity of the liver, headache, costa sternales pain.The Radix Paeoniae Alba has good effect to the treatment trigeminal neuralgia.
Introduce Rhizoma Chuanxiong in medicine of the present invention, the Rhizoma Chuanxiong rhizome contains volatile oil, alkaloid, phenolic constituent, interior lipoid, ferulic acid, Rhizoma Chuanxiong has sedation to the central nervous system of human body and animal body, for smooth muscle the spasmolytic effect is arranged again, so Rhizoma Chuanxiong has treatment headache, the effect of stomachache.
In medicine of the present invention, introduce the Radix Astragali.Prosopalgic patient often follows toothache, eats badly, not sleep well for a long time, causes QI and blood deficiency, and asthenic body is utilized Radix Astragali gas compensation function, and for the patient fills blood, strengthening body strengthens the immunologic function of health, and appetite stimulator promotes the effect of other drug.
In medicine of the present invention, introduce Radix Glycyrrhizae.The main component of Radix Glycyrrhizae is the triterpenoid saponin constituents, as glycyrrhizin, also contains the liquiritin of flavone compound etc.Radix Glycyrrhizae has invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, and relieving spasm to stop pain is in harmonious proportion the function of many medicines.
So medicine of the present invention; Utilize Radix Salviae Miltiorrhizae, the Radix Paeoniae Alba, Rhizoma Chuanxiong is the pain relieving of patient's blood stasis removing, promoting blood circulation to restore menstrual flow, the relieving restlessness that clears away heart-fire, tranquillizing and allaying excitement, eliminate pain is that the patient fills blood with the Radix Astragali, keeps fit body, is used to be in harmonious proportion many medicines with Radix Glycyrrhizae, promotes drug effect.So the present invention is the prosopalgic good medicine of treatment, particularly the trigeminal neuralgia that treatment is caused by cerebrovascular has specially good effect.
Four. the specific embodiment:
Embodiment one: get 3 kilograms of Radix Salviae Miltiorrhizaes, 5 kilograms of the Radix Paeoniae Albas, 1.5 kilograms of Rhizoma Chuanxiongs, 1 kilogram in Radix Glycyrrhizae, 3 kilograms of the Radixs Astragali.Mud is removed in various Chinese herbal medicine remove impurity, handle in accordance with the law, dry, weigh, with Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, the Radix Astragali soaks into section, and totally 7.5 kilograms of stem bodys add 37.5 kilograms in water, and decocting in water is concentrated to about 7.5 kilograms of medicinal liquids.With the Radix Paeoniae Alba, the Radix Glycyrrhizae stem body is weighed, and soaks into section, and it is 6 kilograms in 120 order medicated powder that oven dry is pulverized, and this medicated powder is added in the above-mentioned concentrated medicament, fully mix all, and oven dry, pulverizing is 6.375 kilograms in 120 order medicated powder, adorns a capsule with 0.4 gram, can adorn 15937 capsules.
Embodiment two: get 4.5 kilograms of Radix Salviae Miltiorrhizaes, 7.5 kilograms of the Radix Paeoniae Albas, 2.25 kilograms of Rhizoma Chuanxiongs, 1.5 kilograms in Radix Glycyrrhizae, 4.5 kilograms of the Radixs Astragali.Its processing method does not repeat with embodiment one.With Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, 11.25 kilograms of Radix Astragali stem bodys add 67.5 kilograms in water, and decocting in water is concentrated to about 13.5 kilograms of medicinal liquids.With the Radix Paeoniae Alba, 9 kilograms in Radix Glycyrrhizae stem body medicated powder adds in the above-mentioned concentrated medicament, fully mix all, and oven dry, pulverizing is 9.56 kilograms in 120 order medicated powder, adorns a capsule with 0.4 gram, can adorn 23900 capsules.
Embodiment three: get 6 kilograms of Radix Salviae Miltiorrhizaes, 10 kilograms of the Radix Paeoniae Albas, 3 kilograms of Rhizoma Chuanxiongs, 2 kilograms in Radix Glycyrrhizae, 6 kilograms of the Radixs Astragali.Its processing method does not repeat with embodiment one.With Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, 15 kilograms of Radix Astragali stem bodys add the water 105 kg, and decocting in water is concentrated to about 22.5 kilograms of medicinal liquids.With the Radix Paeoniae Alba, 12 kilograms in Radix Glycyrrhizae stem body medicated powder adds in the above-mentioned concentrated medicament, fully mix all, and oven dry, pulverizing is 12.75 kilograms in 120 order medicated powder, adorns a capsule with 0.4 gram, can adorn 31875 capsules.
Embodiment four: get 5 kilograms of Radix Salviae Miltiorrhizaes, 7 kilograms of the Radix Paeoniae Albas, 2 kilograms of Rhizoma Chuanxiongs, 1.5 kilograms in Radix Glycyrrhizae, 4.5 kilograms of the Radixs Astragali.Its processing method does not repeat with embodiment one.With Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, 11.5 kilograms of Radix Astragali stem bodys add 57.5 kilograms in water, and decocting in water is concentrated to about 11.5 kilograms of medicinal liquids.With the Radix Paeoniae Alba, 8.5 kilograms in Radix Glycyrrhizae stem body medicated powder adds in the above-mentioned concentrated medicament, fully mix all, and oven dry, pulverizing is 9.075 kilograms in 120 order medicated powder, adorns a capsule with 0.4 gram, can adorn 22687 capsules.
Embodiment five: get 5.5 kilograms of Radix Salviae Miltiorrhizaes, 8.25 kilograms of the Radix Paeoniae Albas, 2.25 kilograms of Rhizoma Chuanxiongs, 1.65 kilograms in Radix Glycyrrhizae, 5 kilograms of the Radixs Astragali.Its processing method does not repeat with embodiment one.With Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, 12.75 kilograms of Radix Astragali stem bodys add 76.5 kilograms in water, and decocting in water is concentrated to about 15.3 kilograms of medicinal liquids.With the Radix Paeoniae Alba, 9.9 kilograms in Radix Glycyrrhizae stem body medicated powder adds in the above-mentioned concentrated medicament, fully mix all, and oven dry, pulverizing is 10.54 kilograms in 120 order medicated powder, adorns a capsule with 0.4 gram, can adorn 26343 capsules.
Embodiment six: get 6 kilograms of Radix Salviae Miltiorrhizaes, 9.5 kilograms of the Radix Paeoniae Albas, 2.5 kilograms of Rhizoma Chuanxiongs, 1.8 kilograms in Radix Glycyrrhizae, 5.5 kilograms of the Radixs Astragali.Its processing method does not repeat with embodiment one.With Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, 14 kilograms of Radix Astragali stem bodys add 98 kilograms in water, and decocting in water is concentrated to about 21 kilograms of medicinal liquids.With the Radix Paeoniae Alba, 11.3 kilograms in Radix Glycyrrhizae stem body medicated powder adds in the above-mentioned concentrated medicament, fully mix all, and oven dry, pulverizing is 12 kilograms in 120 order medicated powder, adorns a capsule with 0.4 gram, can adorn 30000 capsules.
Claims (5)
1. the prosopalgic medicine of treatment is characterized in that: made 30～60 parts of Radix Salviae Miltiorrhizaes, 50～100 parts of the Radix Paeoniae Albas, 15～30 parts of Rhizoma Chuanxiongs, 10～20 parts in Radix Glycyrrhizae, 30～60 parts of the Radixs Astragali by following bulk drugs.
2. medicine according to claim 1 is characterized in that: made 50～60 parts of Radix Salviae Miltiorrhizaes, 70～95 parts of the Radix Paeoniae Albas, 20～25 parts of Rhizoma Chuanxiongs, 15～18 parts in Radix Glycyrrhizae, 45～55 parts of the Radixs Astragali by following bulk drugs.
3. method for preparing claim 1 or 2 described medicines is characterized in that: Radix Paeoniae Alba peeling, head, tail and fibrous root, and clean mud drops in the boiling water and boiled 5～10 minutes, pull out and dry or dry, section, the clean mud of Radix Glycyrrhizae, dry, section is got part with Radix Paeoniae Alba sheet and Radix Glycyrrhizae tabellae by proportioning then, pulverizing is 120 purpose powder, and fibrous root is removed in Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong remove impurity, clean mud dries section, and the Radix Astragali is saturating with water infiltration, section is dried or dried, and is stand-by.
4. according to the preparation method of the described medicine of claim 3, it is characterized in that: the dried tablet of Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, the Radix Astragali is got a part mixing by proportioning, add 5～7 times of decocting in water, when boiling into the concentrated medicament of 1～1.5 times of dried medicine weight portion, stop to heat, the Radix Paeoniae Alba and Radix Glycyrrhizae medicated powder are put into this concentrated medicament, fully mix the back oven dry thoroughly, pulverizing is 120 purpose medicated powder.
5. medicine according to claim 1 and 2 is characterized in that: this pharmaceutical dosage form is a powder, or capsule, or pill, or injection.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03126276 CN1225269C (en) | 2003-08-01 | 2003-08-01 | Medicine for treating prospoalgia |
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| Application Number | Priority Date | Filing Date | Title |
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| CN 03126276 CN1225269C (en) | 2003-08-01 | 2003-08-01 | Medicine for treating prospoalgia |
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| CN1483443A CN1483443A (en) | 2004-03-24 |
| CN1225269C true CN1225269C (en) | 2005-11-02 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105853585A (en) * | 2016-06-19 | 2016-08-17 | 练燕华 | Traditional Chinese medicine for treating prosopalgia |
| CN112870270B (en) * | 2021-02-26 | 2022-09-20 | 华北理工大学 | Traditional Chinese medicine preparation for treating ulcerative colitis and preparation method thereof |
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