CN1224420C - 视细胞功能紊乱治疗剂 - Google Patents
视细胞功能紊乱治疗剂 Download PDFInfo
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- CN1224420C CN1224420C CNB998162760A CN99816276A CN1224420C CN 1224420 C CN1224420 C CN 1224420C CN B998162760 A CNB998162760 A CN B998162760A CN 99816276 A CN99816276 A CN 99816276A CN 1224420 C CN1224420 C CN 1224420C
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Ophthalmology & Optometry (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Description
给药组 | (n) | a-波峰的延迟(%平均值±SD) | ||
再灌注后60min | 再灌注后90min | 再灌注后120min | ||
对照药物 | (8) | 195.6±53.5 | 190.8±55.3 | 191.9±60.4 |
试验药物 | (8) | 137.1±47.1* | 141.6±44.8* | 134.4±31.6* |
Claims (4)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US11393998P | 1998-12-24 | 1998-12-24 | |
US60/113,939 | 1998-12-24 |
Publications (2)
Publication Number | Publication Date |
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CN1352565A CN1352565A (zh) | 2002-06-05 |
CN1224420C true CN1224420C (zh) | 2005-10-26 |
Family
ID=22352417
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CNB998162760A Expired - Fee Related CN1224420C (zh) | 1998-12-24 | 1999-12-20 | 视细胞功能紊乱治疗剂 |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1140134A1 (zh) |
JP (1) | JP2002542150A (zh) |
KR (1) | KR20010099928A (zh) |
CN (1) | CN1224420C (zh) |
AR (1) | AR022017A1 (zh) |
AU (1) | AU781049B2 (zh) |
BR (1) | BR9917113A (zh) |
CA (1) | CA2356382A1 (zh) |
MX (1) | MXPA01006449A (zh) |
NO (1) | NO20013146L (zh) |
NZ (1) | NZ513111A (zh) |
TW (1) | TW546145B (zh) |
WO (1) | WO2000038703A1 (zh) |
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US20070032853A1 (en) | 2002-03-27 | 2007-02-08 | Hossainy Syed F | 40-O-(2-hydroxy)ethyl-rapamycin coated stent |
AU2003209297A1 (en) | 2002-01-18 | 2003-09-02 | Massachusetts Eye And Ear Infirmary | Methods and compositions for preserving the viability of photoreceptor cells |
WO2004027027A2 (en) * | 2002-09-18 | 2004-04-01 | Trustees Of The University Of Pennsylvania | Method of inhibiting choroidal neovascularization |
US20050118344A1 (en) | 2003-12-01 | 2005-06-02 | Pacetti Stephen D. | Temperature controlled crimping |
US20060258698A1 (en) | 2005-02-09 | 2006-11-16 | Sreenivasu Mudumba | Liquid formulations for treatment of diseases or conditions |
WO2007019427A2 (en) * | 2005-08-08 | 2007-02-15 | Massachusetts Eye & Ear Infirmary | Methods and compositions for preserving the viability of photoreceptor cells |
US8492400B2 (en) | 2006-02-09 | 2013-07-23 | Santen Pharmaceutical Co., Ltd. | Stable formulations, and methods of their preparation and use |
JP5506378B2 (ja) | 2006-03-23 | 2014-05-28 | 参天製薬株式会社 | 血管透過性に関連する疾患または病気のための製剤および方法 |
EP3868407A4 (en) * | 2018-10-15 | 2022-02-23 | Osaka University | MEDICINE FOR IMPROVING OR PREVENTING RETINA AND/OR PHOTORECEPTION RELATED SYMPTOMS AND METHOD FOR SCREENING SUBSTANCE FOR IMPROVING OR PREVENTING RETINA AND/OR PHOTORECEPTION RELATED SYMPTOMS |
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ATE147936T1 (de) * | 1990-08-23 | 1997-02-15 | Univ New York | Verfahren und zusammensetzungen für die behandlung durch t-zellen vermittelter krankheiten |
IL102414A (en) * | 1991-07-25 | 1996-08-04 | Univ Louisville Res Found | Medicinal preparations for the treatment of ocular inflammation, containing rapamycin |
US5922773A (en) * | 1992-12-04 | 1999-07-13 | The Children's Medical Center Corp. | Glaucoma treatment |
US5597809A (en) * | 1994-06-23 | 1997-01-28 | Massachusetts Eye & Ear Infirmary | Treatment of optic neuritis |
CA2295098A1 (en) * | 1997-06-30 | 1999-01-07 | Allergan Sales, Inc. | Calcium blockers to treat proliferative vitreoretinopathy |
CZ287497B6 (cs) * | 1997-12-30 | 2000-12-13 | Galena, A. S. | Topické oční přípravky s imunosupresivními látkami |
US6376517B1 (en) * | 1998-08-14 | 2002-04-23 | Gpi Nil Holdings, Inc. | Pipecolic acid derivatives for vision and memory disorders |
-
1999
- 1999-12-20 KR KR1020017008060A patent/KR20010099928A/ko not_active Application Discontinuation
- 1999-12-20 WO PCT/JP1999/007161 patent/WO2000038703A1/en not_active Application Discontinuation
- 1999-12-20 BR BR9917113-9A patent/BR9917113A/pt not_active IP Right Cessation
- 1999-12-20 JP JP2000590655A patent/JP2002542150A/ja active Pending
- 1999-12-20 CN CNB998162760A patent/CN1224420C/zh not_active Expired - Fee Related
- 1999-12-20 CA CA002356382A patent/CA2356382A1/en not_active Abandoned
- 1999-12-20 MX MXPA01006449A patent/MXPA01006449A/es unknown
- 1999-12-20 EP EP99959930A patent/EP1140134A1/en not_active Withdrawn
- 1999-12-20 NZ NZ513111A patent/NZ513111A/en unknown
- 1999-12-20 AU AU16906/00A patent/AU781049B2/en not_active Ceased
- 1999-12-22 TW TW088122634A patent/TW546145B/zh not_active IP Right Cessation
- 1999-12-23 AR ARP990106748A patent/AR022017A1/es not_active Application Discontinuation
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2001
- 2001-06-22 NO NO20013146A patent/NO20013146L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2000038703A1 (en) | 2000-07-06 |
KR20010099928A (ko) | 2001-11-09 |
AU781049B2 (en) | 2005-05-05 |
BR9917113A (pt) | 2001-10-23 |
NZ513111A (en) | 2003-10-31 |
JP2002542150A (ja) | 2002-12-10 |
NO20013146L (no) | 2001-08-20 |
AU1690600A (en) | 2000-07-31 |
CA2356382A1 (en) | 2000-07-06 |
EP1140134A1 (en) | 2001-10-10 |
CN1352565A (zh) | 2002-06-05 |
MXPA01006449A (es) | 2002-04-24 |
NO20013146D0 (no) | 2001-06-22 |
TW546145B (en) | 2003-08-11 |
AR022017A1 (es) | 2002-09-04 |
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