CN1223350C - 用作避孕剂的炔雌醇和屈螺酮的药物联合形式 - Google Patents
用作避孕剂的炔雌醇和屈螺酮的药物联合形式 Download PDFInfo
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- CN1223350C CN1223350C CNB008150540A CN00815054A CN1223350C CN 1223350 C CN1223350 C CN 1223350C CN B008150540 A CNB008150540 A CN B008150540A CN 00815054 A CN00815054 A CN 00815054A CN 1223350 C CN1223350 C CN 1223350C
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- Prior art keywords
- drospirenone
- ethinylestradiol
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- 229920001155 polypropylene Polymers 0.000 description 1
- 239000005033 polyvinylidene chloride Substances 0.000 description 1
- 239000000651 prodrug Substances 0.000 description 1
- 229940002612 prodrug Drugs 0.000 description 1
- 239000000583 progesterone congener Substances 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 229940080313 sodium starch Drugs 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 125000000185 sucrose group Chemical group 0.000 description 1
- 229940126703 systemic medication Drugs 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- LLZRNZOLAXHGLL-UHFFFAOYSA-J titanic acid Chemical group O[Ti](O)(O)O LLZRNZOLAXHGLL-UHFFFAOYSA-J 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 229960002622 triacetin Drugs 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24095399P | 1999-08-31 | 1999-08-31 | |
| EP99202826 | 1999-08-31 | ||
| US60/240,953 | 1999-08-31 | ||
| EP99202826.6 | 1999-08-31 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2005100992135A Division CN1879632A (zh) | 1999-08-31 | 2000-08-31 | 包含炔雌醇和屈螺酮的药物组合物、其应用和制备方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1407895A CN1407895A (zh) | 2003-04-02 |
| CN1223350C true CN1223350C (zh) | 2005-10-19 |
Family
ID=26153358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB008150540A Expired - Lifetime CN1223350C (zh) | 1999-08-31 | 2000-08-31 | 用作避孕剂的炔雌醇和屈螺酮的药物联合形式 |
Country Status (11)
| Country | Link |
|---|---|
| CN (1) | CN1223350C (no) |
| BG (2) | BG109749A (no) |
| CA (1) | CA2382426C (no) |
| EE (1) | EE05317B1 (no) |
| HR (1) | HRP20020258B1 (no) |
| IL (2) | IL197396A (no) |
| MX (1) | MXPA02002043A (no) |
| NO (3) | NO327588B3 (no) |
| RU (4) | RU2449796C9 (no) |
| SK (1) | SK287634B6 (no) |
| UA (1) | UA81387C2 (no) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1625849A1 (en) * | 2004-08-09 | 2006-02-15 | Liconsa, Liberacion Controlada de Sustancias Activas, S.A. | Pharmaceutical composition comprising drospirenone and ethynylestradiol |
| CN101489563A (zh) * | 2006-07-06 | 2009-07-22 | 拜耳先灵医药股份有限公司 | 用于避孕和预防先天性畸形风险的药物制剂 |
| JP6285866B2 (ja) | 2011-11-23 | 2018-02-28 | セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． | 天然複合ホルモン補充製剤および療法 |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| RU2618471C2 (ru) * | 2012-12-03 | 2017-05-03 | Закрытое Акционерное Общество "Вертекс" | Пероральная фармацевтическая композиция диуретика и ингибитора АПФ в микронизированной форме, лекарственное средство и его применение |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| KR20170005819A (ko) | 2014-05-22 | 2017-01-16 | 쎄러퓨틱스엠디, 인코퍼레이티드 | 천연 복합 호르몬 대체 제형 및 요법 |
| CN108606963B (zh) * | 2017-12-27 | 2021-05-18 | 上海长海医院 | 含有屈螺酮和雌激素的复方避孕贴、制备方法及应用 |
| CN111529482A (zh) * | 2020-05-20 | 2020-08-14 | 祝培 | 十一酸睾酮缓释植入剂及其应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2652761C2 (de) * | 1976-11-16 | 1985-11-21 | Schering AG, 1000 Berlin und 4709 Bergkamen | 15,16-Methylen-Spirolactone, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel |
| DE4344462C2 (de) * | 1993-12-22 | 1996-02-01 | Schering Ag | Zusammensetzung für die Empfängnisverhütung |
| DE4411585A1 (de) * | 1994-03-30 | 1995-10-05 | Schering Ag | Pharmazeutisches Kombinationspräparat zur hormonalen Kontrazeption |
| KR100518102B1 (ko) * | 1996-07-26 | 2005-10-04 | 와이어쓰 | 프로게스틴과 에스트로겐의 혼합물을 포함하는 단일상 피임약 키트 |
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2000
- 2000-08-31 MX MXPA02002043A patent/MXPA02002043A/es active IP Right Grant
- 2000-08-31 EE EEP200900049A patent/EE05317B1/xx not_active IP Right Cessation
- 2000-08-31 CN CNB008150540A patent/CN1223350C/zh not_active Expired - Lifetime
- 2000-08-31 RU RU2002107987/15A patent/RU2449796C9/ru not_active IP Right Cessation
- 2000-08-31 CA CA002382426A patent/CA2382426C/en not_active Expired - Lifetime
- 2000-08-31 UA UA2002032519A patent/UA81387C2/xx unknown
- 2000-08-31 SK SK257-2002A patent/SK287634B6/sk not_active IP Right Cessation
- 2000-08-31 RU RU2002107987/15K patent/RU2269342C2/ru not_active IP Right Cessation
-
2002
- 2002-03-20 BG BG109749A patent/BG109749A/bg unknown
- 2002-03-20 BG BG106533A patent/BG65204B1/bg unknown
- 2002-03-27 HR HR20020258A patent/HRP20020258B1/xx not_active IP Right Cessation
-
2005
- 2005-10-14 RU RU2005131868/15A patent/RU2396082C2/ru active
-
2008
- 2008-09-08 NO NO20083854A patent/NO327588B3/no not_active IP Right Cessation
-
2009
- 2009-03-04 IL IL197396A patent/IL197396A/en active IP Right Grant
- 2009-05-07 NO NO20091809A patent/NO20091809L/no not_active Application Discontinuation
- 2009-08-19 IL IL200482A patent/IL200482A0/en unknown
-
2010
- 2010-02-26 NO NO2010004C patent/NO2010004I1/no unknown
- 2010-04-14 RU RU2010114825/15A patent/RU2482853C2/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| IL200482A0 (en) | 2011-07-31 |
| BG106533A (bg) | 2002-10-31 |
| RU2269342C9 (ru) | 2007-10-27 |
| RU2482853C2 (ru) | 2013-05-27 |
| EE200900049A (et) | 2009-10-15 |
| NO327588B1 (no) | 2009-08-31 |
| RU2396082C2 (ru) | 2010-08-10 |
| BG65204B1 (bg) | 2007-07-31 |
| RU2269342C2 (ru) | 2006-02-10 |
| RU2449796C9 (ru) | 2007-10-27 |
| RU2005131868A (ru) | 2007-04-20 |
| NO20083854L (no) | 2002-04-26 |
| SK287634B6 (sk) | 2011-04-05 |
| UA81387C2 (en) | 2008-01-10 |
| IL197396A (en) | 2010-04-29 |
| EE05317B1 (et) | 2010-08-16 |
| RU2449796C2 (ru) | 2006-02-10 |
| NO20091809L (no) | 2002-04-26 |
| BG109749A (bg) | 2008-06-30 |
| CA2382426C (en) | 2006-02-28 |
| CA2382426A1 (en) | 2001-03-08 |
| MXPA02002043A (es) | 2003-08-20 |
| HRP20020258A2 (en) | 2005-02-28 |
| RU2010114825A (ru) | 2011-10-20 |
| CN1407895A (zh) | 2003-04-02 |
| NO2010004I1 (no) | 2010-03-22 |
| SK2572002A3 (en) | 2002-11-06 |
| HRP20020258B1 (en) | 2007-05-31 |
| NO327588B3 (no) | 2011-05-16 |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
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Owner name: SCHERING AG Free format text: FORMER NAME OR ADDRESS: SCHERING CORP. |
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Address after: Berlin Patentee after: Schering AG Address before: Berlin Patentee before: SCHERING CORP (US) |
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Owner name: BAYER SCHERING PHARMACEUTICAL CO. Free format text: FORMER NAME OR ADDRESS: SCHERING AG |
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Address after: Berlin Patentee after: Schering AG Address before: Berlin Patentee before: Schering AG |
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Owner name: BAYER PHARMA AG Free format text: FORMER NAME: SCHERING AG |
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