HRP20020258B1 - Pharmaceutical combination of ethinylestradiol and drospirenone for use as a contraceptive - Google Patents
Pharmaceutical combination of ethinylestradiol and drospirenone for use as a contraceptiveInfo
- Publication number
- HRP20020258B1 HRP20020258B1 HR20020258A HRP20020258A HRP20020258B1 HR P20020258 B1 HRP20020258 B1 HR P20020258B1 HR 20020258 A HR20020258 A HR 20020258A HR P20020258 A HRP20020258 A HR P20020258A HR P20020258 B1 HRP20020258 B1 HR P20020258B1
- Authority
- HR
- Croatia
- Prior art keywords
- drospirenone
- ethinylestradiol
- contraceptive
- pharmaceutical combination
- active ingredient
- Prior art date
Links
- METQSPRSQINEEU-UHFFFAOYSA-N dihydrospirorenone Natural products CC12CCC(C3(CCC(=O)C=C3C3CC33)C)C3C1C1CC1C21CCC(=O)O1 METQSPRSQINEEU-UHFFFAOYSA-N 0.000 title abstract 3
- METQSPRSQINEEU-HXCATZOESA-N drospirenone Chemical compound C([C@]12[C@H]3C[C@H]3[C@H]3[C@H]4[C@@H]([C@]5(CCC(=O)C=C5[C@@H]5C[C@@H]54)C)CC[C@@]31C)CC(=O)O2 METQSPRSQINEEU-HXCATZOESA-N 0.000 title abstract 3
- 229960004845 drospirenone Drugs 0.000 title abstract 3
- BFPYWIDHMRZLRN-UHFFFAOYSA-N 17alpha-ethynyl estradiol Natural products OC1=CC=C2C3CCC(C)(C(CC4)(O)C#C)C4C3CCC2=C1 BFPYWIDHMRZLRN-UHFFFAOYSA-N 0.000 title abstract 2
- BFPYWIDHMRZLRN-SLHNCBLASA-N Ethinyl estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 BFPYWIDHMRZLRN-SLHNCBLASA-N 0.000 title abstract 2
- 229960002568 ethinylestradiol Drugs 0.000 title abstract 2
- 239000003433 contraceptive agent Substances 0.000 title 1
- 230000002254 contraceptive effect Effects 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 2
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24095399P | 1999-08-31 | 1999-08-31 | |
EP99202826 | 1999-08-31 | ||
PCT/IB2000/001213 WO2001015701A1 (en) | 1999-08-31 | 2000-08-31 | Pharmaceutical combination of ethinylestradiol and drospirenone for use as a contraceptive |
Publications (2)
Publication Number | Publication Date |
---|---|
HRP20020258A2 HRP20020258A2 (en) | 2005-02-28 |
HRP20020258B1 true HRP20020258B1 (en) | 2007-05-31 |
Family
ID=26153358
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HR20020258A HRP20020258B1 (en) | 1999-08-31 | 2002-03-27 | Pharmaceutical combination of ethinylestradiol and drospirenone for use as a contraceptive |
Country Status (11)
Country | Link |
---|---|
CN (1) | CN1223350C (no) |
BG (2) | BG109749A (no) |
CA (1) | CA2382426C (no) |
EE (1) | EE05317B1 (no) |
HR (1) | HRP20020258B1 (no) |
IL (2) | IL197396A (no) |
MX (1) | MXPA02002043A (no) |
NO (3) | NO327588B3 (no) |
RU (4) | RU2449796C9 (no) |
SK (1) | SK287634B6 (no) |
UA (1) | UA81387C2 (no) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1625849A1 (en) * | 2004-08-09 | 2006-02-15 | Liconsa, Liberacion Controlada de Sustancias Activas, S.A. | Pharmaceutical composition comprising drospirenone and ethynylestradiol |
CN101489563A (zh) * | 2006-07-06 | 2009-07-22 | 拜耳先灵医药股份有限公司 | 用于避孕和预防先天性畸形风险的药物制剂 |
JP6285866B2 (ja) | 2011-11-23 | 2018-02-28 | セラピューティックスエムディー インコーポレーテッドTherapeuticsmd, Inc. | 天然複合ホルモン補充製剤および療法 |
US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
RU2618471C2 (ru) * | 2012-12-03 | 2017-05-03 | Закрытое Акционерное Общество "Вертекс" | Пероральная фармацевтическая композиция диуретика и ингибитора АПФ в микронизированной форме, лекарственное средство и его применение |
US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
KR20170005819A (ko) | 2014-05-22 | 2017-01-16 | 쎄러퓨틱스엠디, 인코퍼레이티드 | 천연 복합 호르몬 대체 제형 및 요법 |
CN108606963B (zh) * | 2017-12-27 | 2021-05-18 | 上海长海医院 | 含有屈螺酮和雌激素的复方避孕贴、制备方法及应用 |
CN111529482A (zh) * | 2020-05-20 | 2020-08-14 | 祝培 | 十一酸睾酮缓释植入剂及其应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2652761C2 (de) * | 1976-11-16 | 1985-11-21 | Schering AG, 1000 Berlin und 4709 Bergkamen | 15,16-Methylen-Spirolactone, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel |
DE4344462C2 (de) * | 1993-12-22 | 1996-02-01 | Schering Ag | Zusammensetzung für die Empfängnisverhütung |
DE4411585A1 (de) * | 1994-03-30 | 1995-10-05 | Schering Ag | Pharmazeutisches Kombinationspräparat zur hormonalen Kontrazeption |
KR100518102B1 (ko) * | 1996-07-26 | 2005-10-04 | 와이어쓰 | 프로게스틴과 에스트로겐의 혼합물을 포함하는 단일상 피임약 키트 |
-
2000
- 2000-08-31 MX MXPA02002043A patent/MXPA02002043A/es active IP Right Grant
- 2000-08-31 EE EEP200900049A patent/EE05317B1/xx not_active IP Right Cessation
- 2000-08-31 CN CNB008150540A patent/CN1223350C/zh not_active Expired - Lifetime
- 2000-08-31 RU RU2002107987/15A patent/RU2449796C9/ru not_active IP Right Cessation
- 2000-08-31 CA CA002382426A patent/CA2382426C/en not_active Expired - Lifetime
- 2000-08-31 UA UA2002032519A patent/UA81387C2/xx unknown
- 2000-08-31 SK SK257-2002A patent/SK287634B6/sk not_active IP Right Cessation
- 2000-08-31 RU RU2002107987/15K patent/RU2269342C2/ru not_active IP Right Cessation
-
2002
- 2002-03-20 BG BG109749A patent/BG109749A/bg unknown
- 2002-03-20 BG BG106533A patent/BG65204B1/bg unknown
- 2002-03-27 HR HR20020258A patent/HRP20020258B1/xx not_active IP Right Cessation
-
2005
- 2005-10-14 RU RU2005131868/15A patent/RU2396082C2/ru active
-
2008
- 2008-09-08 NO NO20083854A patent/NO327588B3/no not_active IP Right Cessation
-
2009
- 2009-03-04 IL IL197396A patent/IL197396A/en active IP Right Grant
- 2009-05-07 NO NO20091809A patent/NO20091809L/no not_active Application Discontinuation
- 2009-08-19 IL IL200482A patent/IL200482A0/en unknown
-
2010
- 2010-02-26 NO NO2010004C patent/NO2010004I1/no unknown
- 2010-04-14 RU RU2010114825/15A patent/RU2482853C2/ru active
Also Published As
Publication number | Publication date |
---|---|
IL200482A0 (en) | 2011-07-31 |
BG106533A (bg) | 2002-10-31 |
RU2269342C9 (ru) | 2007-10-27 |
CN1223350C (zh) | 2005-10-19 |
RU2482853C2 (ru) | 2013-05-27 |
EE200900049A (et) | 2009-10-15 |
NO327588B1 (no) | 2009-08-31 |
RU2396082C2 (ru) | 2010-08-10 |
BG65204B1 (bg) | 2007-07-31 |
RU2269342C2 (ru) | 2006-02-10 |
RU2449796C9 (ru) | 2007-10-27 |
RU2005131868A (ru) | 2007-04-20 |
NO20083854L (no) | 2002-04-26 |
SK287634B6 (sk) | 2011-04-05 |
UA81387C2 (en) | 2008-01-10 |
IL197396A (en) | 2010-04-29 |
EE05317B1 (et) | 2010-08-16 |
RU2449796C2 (ru) | 2006-02-10 |
NO20091809L (no) | 2002-04-26 |
BG109749A (bg) | 2008-06-30 |
CA2382426C (en) | 2006-02-28 |
CA2382426A1 (en) | 2001-03-08 |
MXPA02002043A (es) | 2003-08-20 |
HRP20020258A2 (en) | 2005-02-28 |
RU2010114825A (ru) | 2011-10-20 |
CN1407895A (zh) | 2003-04-02 |
NO2010004I1 (no) | 2010-03-22 |
SK2572002A3 (en) | 2002-11-06 |
NO327588B3 (no) | 2011-05-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A1OB | Publication of a patent application | ||
ARAI | Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application | ||
B1PR | Patent granted | ||
PNAN | Change of the applicant name, address/residence |
Owner name: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT, DE |
|
PNAN | Change of the applicant name, address/residence |
Owner name: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT, PATENTS |
|
PNAN | Change of the applicant name, address/residence |
Owner name: BAYER PHARMA AKTIENGESELLSCHAFT, DE |
|
ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20190725 Year of fee payment: 20 |
|
PB20 | Patent expired after termination of 20 years |
Effective date: 20200831 |