CN1211435A - Tiepifengdou infused powder preparation and its compounding technique - Google Patents

Abstract

A dissolvable granular preparation for treating the dificiency of nutrient fluid or vital essence of heart, liver, lung, stomach and kidney with 51.9%-90.45% of effective rate is prepared from dendrobium tosaense stem, American ginseng and dextrose through extraction, filter, concentrating, separation, stirring, granulating baking, sterilization and packing.

Description

Tiepifengdou infused powder and reparation technology thereof

The present invention relates to a kind of Tiepifengdou infused powder and reparation technology thereof, belong to a kind of Chinese herbal and crude drugs preparations and production technology thereof.

The present invention is that continue my name is called " Tiepifengdou oral liquid and compound method thereof ", application number is 96102780.0, the applying date is the another application after the application on March 27th, 96, the Tiepifengdou oral liquid that provides in person in above-mentioned application is a kind of can directly taking, have nourishing YIN and moistening the lung, YIN nourishing and the production of body fluid promoting, the nourishing the stomach that clears away heart-fire, improve immune function of human body, keep fit brain-strengthening, the nutrient health of slow down aging.In order to make this rare medicinal herbs of Herba Dendrobii, obtain more in depth developing, serve society more widely, be fit to the needs of various people's medications.

The object of the present invention is to provide a kind of another kind of dosage form of health product of Herba Dendrobii, i.e. Tiepifengdou infused powder.

Another object of the present invention is to provide the reparation technology of Tiepifengdou infused powder.

Realize that technical scheme scheme of the present invention is as follows:

Described Tiepifengdou infused powder is that the processed goods Herba Dendrobii with Herba Dendrobii is that principal agent adds a certain proportion of Radix Panacis Quinquefolii, glucose through formulated electuary.It is characterized in that described Tiepifengdou infused powder prescription is, Herba Dendrobii 1000 grams, Radix Panacis Quinquefolii 800 grams, glucose 6000 grams are mixed with 2000 bags of the Tiepifengdou infused powders of every bag 3 gram.

The preparing process of above-mentioned Tiepifengdou infused powder is as follows:

A. the Herba Dendrobii of specified quantity is pulverized be Powdered → soak → extract 3 to 4 times → filter → concentrate → separate → concentrated → extractum;

B. the Radix Panacis Quinquefolii of specified quantity is cut into slices → soaked → extract → filter → concentrate → extractum;

C. the Herba Dendrobii residue after extracting through four times among the flow process A is added boiled water produce polysaccharide → filter polysaccharide slime formers → concentrate back adds ethanol polysaccharide is separated out;

D. preparation: the dendrobium officinale extracturm that will produce by flow process A and mix by the Radix Panacis Quinquefolii extractum that flow process B produces and to stir, even heating, the pro rata adding of Herba Dendrobii polysaccharide that will produce by flow process C stirs then, Radix Panacis Quinquefolii, dendrobium officinale extracturm;

E. gained Radix Panacis Quinquefolii among the flow process D, dendrobium officinale extracturm are added the specified quantity glucose stir → granulate → dry → sieve → airpillow-dry → mixing sterilization → packing gets product.

Tiepifengdou infused powder of the present invention is that the nourishing YIN Chinese medicine of distinguished YIN nourishing function---Herba Dendrobii is a principal agent to have, and is equipped with rare medicinal herbs such as Radix Panacis Quinquefolii and refines through science and form.Have nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, the effect of the nourishing YIN that clears away heart-fire.Cure mainly the spiritlessness and weakness that causes because of the five internal organs deficiency of YIN, deficiency of YIN dry cough, thirsty and dry pharynx is had sore throat, and it is sterile etc. that dysphoria and insomnia is wedded for a long time.Be particularly useful for cancer patient postoperative or treatment back and chronic hepatopathy, heart disease, diabetes the above-mentioned symptom occurs person.Carry out observation of curative effect 293 routine case total effective rates 90.45%, obvious effective rate 51.19%, invalid 9.55% according to clinical hospital.

The detailed processing technology and the most preferred embodiment of Tiepifengdou infused powder of the present invention are described below:

A. Herba Dendrobii is got 1000 grams and is pulverized and to be powdery, it is dropped in extraction pot, by the throwing amount 11 extraordinarily water purification soaked 4-6 hour, heat up then 80 ℃ and be incubated 6 hours, cooled off 1 hour, put into filtering jar and filter.Residue in the extraction pot is all thrown water purification by 10 times and is extracted 3-4 time and filter as above-mentioned method continuously.Extracting solution after the above filtration is put into high-efficiency evaporator,, when liquid cumulative volume to be extracted is concentrated into 20 to 30 liters, puts into the evaporation of worn-out mouthful of pot internal heating and do at 80 ℃ of following evacuation concentrating under reduced pressure.Add 30 liters of dissolvings of pure water again, cold filtration then, filtrate is concentrated into proportion in worn-out mouthful of pot of suction again and is 1.20-1.25, and is stand-by.

B. Radix Panacis Quinquefolii is cut into lamellar and takes out 800 grams, drop in the extraction pot,, soaked 2 hours, be warming up to 80 ℃ gradually in jar, be incubated 3 hours by 15 extraordinarily entry of inventory.Putting into filtering jar then while hot filters.Filtrate is pressed in the high-efficiency evaporator concentrates, temperature is no more than 80 ℃, be concentrated into original volume 1/3 for extremely.

The residue of Radix Panacis Quinquefolii extracts respectively 3 times, adds the water purification amount at every turn and be 10 times of Radix Panacis Quinquefolii.Emit after 3 hours in insulation under 80 ℃, refilter, operate the same.The extracting solution that extracts is several times mixed, and it is interior concentrated to be pressed into concentration tank, is evacuated to the Alcohol-settling tank internal cooling at 1/4 o'clock of volume during to former putting into, and adds ethanol, precipitate with ethanol 24-36 hour, draws supernatant liquid and again the bottom precipitation is carried out the secondary precipitate with ethanol 24 hours.Twice precipitated liquid merging refiltered.Filtrate is squeezed in the high-efficiency evaporator, reclaim ethanol, be concentrated into original volume 1/3 at 60 ℃-80 ℃.Move to evaporation boiler in the high-efficiency evaporator and be concentrated into proportion about 1.20～1.25 and be Radix Panacis Quinquefolii extractum, stand-by.

C. the residue after Herba Dendrobii extract extracts through flow process A adds 2.5 liters in boiled water, extract and divide sugar, through strictness filter polysaccharide slime formers, mucus concentrates the back and adds ethanol and use polysaccharide to separate out, and filters the back and drops into worn-out mouthful of pot.Volatilization ethanol is to qualified.

D. will be respectively according to the dendrobium officinale extracturm of A, the extraction of B flow process, Radix Panacis Quinquefolii extractum mixes stirring, and even heating will add in proportion according to the Herba Dendrobii polysaccharide that flow process C extracts then, stirs, and reconcentration gets Radix Panacis Quinquefolii, dendrobium officinale extracturm.

E. glucose 6000 gram is poured into blender and mixed all will pour into by Radix Panacis Quinquefolii, dendrobium officinale extracturm that the D flow process is produced again and mix all, move on in the comminutor again and granulate.Put into steel disk then equably and dry, sieve through whole sticking that granule is qualified granule between the 3-10 mesh sieve again.Qualified granule being put into ebullated dryer is dried to moisture content and is lower than 5% for qualified again.

All granules are poured into mixer after with infrared ray and high temperature sterilization to be mixed.And after packing finished product.

Now illustrate the function of this medicine:

Open *, woman, 51 years old, diagnosis: chronic pharyngitis.

Simple medical history: after the tonsil enucleation, dry pharynx seemingly has the foreign body screens before 20 years, and the self-induction resistance reduces, myasthenia of limbs, easy catching a cold.

Clinical examination: pharyngeal hyperemia, both sides tonsillar fossa surface irregularity, viscous secretion band blood, the retropharyneal folliculosis color is red, and the both sides red closure of pachyderma circumscripta color is not good enough, and body of the tongue is general red, white and thin fur, thready and soft pulse.

Tiepifengdou infused powder: three guarantees every day (9 gram) divide clothes, totally 10 days three times.

Clinical efficacy: bottleneck throat transference cure after ten days is complete.

Claims (2)

1. a Tiepifengdou infused powder is that the processed goods Herba Dendrobii with Herba Dendrobii is that principal agent adds a certain proportion of Radix Panacis Quinquefolii, glucose, and the electuary through formulated is characterized in that; The prescription of described Tiepifengdou infused powder is Herba Dendrobii 1000 gram, Radix Panacis Quinquefolii 800 grams, and glucose 6000 grams are mixed with 2000 bags of the Tiepifengdou infused powders of every bag 3 gram.

2. the compound method of Tiepifengdou infused powder according to claim 1 is characterized in that;

A. the Herba Dendrobii of specified quantity is pulverized be Powdered → soak → extract 3 to 4 times → filter → concentrate → separate → concentrated → extractum;

B. the Radix Panacis Quinquefolii of specified quantity is cut into slices → soaked → extract → filter → concentrate → extractum;

C. the Herba Dendrobii residue after extracting through four times among the flow process A is added boiled water produce polysaccharide → filter polysaccharide slime formers → concentrate back adds ethanol polysaccharide is separated out;

D. preparation: the dendrobium officinale extracturm that will produce by flow process A and mix by the Radix Panacis Quinquefolii extractum that flow process B produces and to stir, even heating, the pro rata adding of Herba Dendrobii polysaccharide that will produce by flow process C stirs then, Radix Panacis Quinquefolii, dendrobium officinale extracturm;

E. gained Radix Panacis Quinquefolii among the flow process D, dendrobium officinale extracturm are added the specified quantity glucose stir → granulate → dry → sieve → airpillow-dry → mixing sterilization → packing gets product.