CN1211108C - Chinese patent drug for treating thrombus obliterating angiitis - Google Patents
Chinese patent drug for treating thrombus obliterating angiitis Download PDFInfo
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Abstract
The present invention relates to a Chinese patent drug for treating thromboangiitis obliterans, which is prepared from astragalus root, long-noded pit viper, scorpion, air potato, safflower, peach kernel, hemlock parsley, red peony root, double blossom, human placenta, angelica, radix achyranthe, leech, liquorice, monkshood, figwort, red sage root, coix seed, spatholobus stem, ground beeltle, dragon blood, frankincense, corydalis, patrinia, etc. according to a certain weight proportion. The Chinese patent drug is capable of clearing heat, removing toxicity, regulating vital energy, activating blood, warming yang, dispelling wind, dredging channels, warming and dispelling cold and evil, removing pyretic toxicity and smoothing vital blood circulation, and has the characteristics of obvious therapeutic effect, rapid symptom elimination, convenient taking, no toxic or side effect, low therapeutic cost, etc. The effective rate is 95%, the effectual rate is 77.8%, and the healing rate is 50%.
Description
The present invention relates to a kind of Chinese patent medicine, specifically a kind of Chinese patent medicine for the treatment of thromboangiitis obliterans.
Thromboangiitis obliterans is that a kind of limbs disability rate is very high, and in can causing, the chronic nonsuppurative inflammation of petty action vein blood vessel obturation, mainly involve in the extremity, small artery.Clinical manifestation is afraid of cold for suffering from the limb far-end, feeling of numbness is arranged, foot and shank have the pain of delocalization, continue intermittent claudication then to occur, and toes have rest pain, the aggravation at night, the toe-end temperature reduces, and bleach even be purple dark-coloured, be the able-bodied disease of a kind of serious harm human body, the only a few severe patient even the amputation of need going bring great psychic pain and financial burden to the patient.To the scorching disease of rhomboembolia type arteries and veins villous themeda, doctor trained in Western medicine does not still have active drug and method treatment at present, vasodilation gallbladder ginseng, kallidinogenase etc., and it is invalid to have proved iron deficiency acroesthesia clinically.Blood vessel lytic agent urokinase, streptokinase etc. also can only be effective to acute thrombotic vascular occlusion, and be invalid to chronic occlusion, and toxic and side effects is big, can not effect a radical cure, treatment cost height.
The object of the present invention is to provide a kind of heat-clearing and toxic substances removing, the network blood of regulating the flow of vital energy, warming YANG dispelling wind and removing obstruction in the collateral, make the cold-evil be able to temperature and loose, pyretic toxicity is able to removing summer-heat, and QI-blood circulation is unobstructed, and no pain, to have no side effect, treat cost low, and the Chinese patent medicine of treatment thromboangiitis obliterans.
Solution of the present invention is based on motherland's medical science to pathogenetic understanding of thromboangiitis obliterans and Therapeutic Principle.Study with reference to modern pharmacology, select for use heat-clearing and toxic substances removing, promoting blood circulation to remove obstruction in the collateral class medicine formulated, existing blood viscosity lowering, improve the effect of hemorheology, the LBF of increasing amount is arranged again, improve the limbs microcirculation, promote the effect of side limb circulation, can obviously improve suffer from that limb is heavy, pain, symptom such as peep brokenly, rot, to reach the effect of healing thromboangiitis obliterans.
It is formulated by pure Chinese medicine that the present invention treats the Chinese patent medicine of thromboangiitis obliterans, so without any side effects to human body.
The present invention treat the thromboangiitis obliterans Chinese patent medicine formula and weight proportion as follows: Radix Astragali 30-50 part, Agkistrodon 6-15 part, Scorpio 2-6 part, Rhizoma Dioscoreae Bulbiferae 10-20 part, Flos Carthami 6-12 part, Semen Persicae 12-20 part, Rhizoma Chuanxiong 10-15 part, Radix Paeoniae Rubra 10-15 part, Flos Lonicerae 20-30 part, Placenta Hominis 15-20 part, Radix Angelicae Sinensis 10-30 part, Radix Cyathulae 10-20 part, Hirudo 3-6 part, Radix Glycyrrhizae 9-12 part, Radix Aconiti Lateralis Preparata 6-8 part, Radix Scrophulariae 10-20 part, Radix Salviae Miltiorrhizae 20-40 part, Semen Coicis 20-30 part, Caulis Spatholobi 12-15 part, Eupolyphaga Seu Steleophaga 12-15 part, Sanguis Draxonis 6-9 part, Olibanum 5-9 part, Herba Violae 20-40 part, Herba Patriniae 12-20 part.
Use the above-mentioned prescription treatment thromboangiitis obliterans of Chinese patent medicine of the present invention, curative effect is obvious, and it is rapid to eliminate symptom, and taking convenience has no side effect, and the treatment cost is low, effective percentage 95%, obvious effective rate 77.8%, cure rate 50%.
The antipyretic and antidotal type medicine is Flos Lonicerae, Semen Coicis, Herba Violae, Rhizoma Dioscoreae Bulbiferae, Herba Patriniae, Radix Scrophulariae in the Chinese patent medicine of the present invention; The class of invigorating blood circulation medicine is: Flos Carthami, Radix Paeoniae Rubra, Semen Persicae, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Radix Cyathulae, Hirudo, Radix Salviae Miltiorrhizae, Caulis Spatholobi, Eupolyphaga Seu Steleophaga, Olibanum; Dispelling, collateral-activating class medicine is: Agkistrodon, Scorpio; Warming YANG class medicine is: Radix Aconiti Lateralis Preparata, Placenta Hominis; Promoting tissue regeneration and ulcer healing class medicine is a Resina Draconis; QI invigorating class medicine is the Radix Astragali.
Prove according to Traditional Chinese medical theory and modern medicine study, the nature and flavor of various composition medicines in the Chinese patent medicine of the present invention, return through and useful effect as follows:
Flos Lonicerae: nature and flavor are sweet, cold, return lung, stomach, large intestine channel, and heat-clearing and toxic substances removing contains bios, reseda flavin etc., has broad-spectrum antibacterial action.(1. seeing " Chinese medicine summary " 90 pages, Yu Daxiang chief editor, in June, 1985, People's Health Publisher)
Herba Violae: nature and flavor hardship, suffering, cold, GUIXIN, Liver Channel, heat-clearing and toxic substances removing contains glycoside, flavonoid etc., and broad-spectrum antibacterial action is arranged.(the same 1. 91-92 page or leaf)
Semen Coicis: nature and flavor are sweet, light, be slightly cold, and return spleen, lung, kidney channel, and row is dense for spleen invigorating eliminating dampness by diuresis, heat clearing away, contains Semen Coicis oil, coixenolide etc.(the same 1. 106 pages)
Herba Patriniae: nature and flavor suffering, hardship, be slightly cold, return stomach, large intestine, Liver Channel, heat-clearing and toxic substances removing, the pain that disappears evacuation of pus, stasis-dispelling and pain-killing.(2. see " Chinese materia medica " 61 pages, insult a principle chief editor, nineteen eighty-three December, Shanghai science tech publishing house)
Radix Scrophulariae: nature and flavor hardship, salty, cold, nourishing YIN and clearing away heat, the detoxifcation softening the hard mass contains harpagoside, alkaloid etc., and bacillus pyocyaneus is had inhibitory action.(the same 1. 94 pages)
Rhizoma Dioscoreae Bulbiferae: nature and flavor hardship, cold, return lung, Liver Channel, heat-clearing and toxic substances removing, eliminating stagnation removing heat from blood, (the same 2. 180 pages)
Flos Carthami: nature and flavor suffering, temperature, GUIXIN, Liver Channel, promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing contains carthamin, Carthamus yellow etc., and the anticoagulant effect is arranged.(the same 1. 123 pages)
Radix Paeoniae Rubra: the nature and flavor hardship, be slightly cold, return Liver Channel, blood circulation promoting and blood stasis dispelling, clearing away heat and cooling blood contains Radix Paeoniae Rubra first element, second element, benzoic acid etc., anticoagulant is arranged and reduce the effect of fibrinogen level.(the same 1. 122 pages)
Semen Persicae: nature and flavor hardship, sweet, flat, GUIXIN, liver, large intestine channel, removing blood stasis contains amygdalin, fatty wet goods, and remarkable inhibition hemagglutinative function is arranged.(the same 1. 122)
Rhizoma Chuanxiong: nature and flavor suffering, temperature, return liver, gallbladder, heart color warp, promoting flow of QI and blood, wind-expelling pain-stopping contains alkaloid, volatilization wet goods, can reduce plasma viscosity, and can directly expand peripheral vessels.(the same 1. 123 pages)
Radix Salviae Miltiorrhizae: the nature and flavor hardship, be slightly cold, GUIXIN, Liver Channel, blood circulation promoting and blood stasis dispelling contains TANSHINONES first, second, the third gradegrade C, can expand peripheral vessels, and anticoagulation and antiplatelet aggregative activity are arranged.(the same 1. 122 pages)
Radix Cyathulae: nature and flavor hardship, acid, flat, blood circulation promoting and blood stasis dispelling contains alkaloid etc., and the effect that improves erythrocyte deformability is arranged.(the same 1. 123-124 page or leaf)
Caulis Spatholobi: nature and flavor hardship, little sweet, warm, return liver, kidney channel, to enrich blood and invigorate blood circulation, channels sootheing and network vessel quickening contains milletol etc., and the effect of microcirculation improvement is arranged.(the same 1. 124-125 page or leaf)
Olibanum: nature and flavor suffering, hardship, temperature have promoting blood circulation and stopping pain, the effect of detumescence and promoting granulation.(the same 1. 125 pages)
Radix Angelicae Sinensis: nature and flavor are sweet, hot, warm, and GUIXIN, liver, spleen channel are enriched blood and invigorated blood circulation, and contain volatile oil, alkaloid etc., and the effect that reduces fibrinogen level is arranged.(the same 1. 132 pages)
Hirudo: nature and flavor are salty, bitter, flat, return Liver Channel, removing blood stasis, and hirudin has anticoagulation.(the same 2. 162 pages)
Eupolyphaga Seu Steleophaga: nature and flavor are salty, cold, return Liver Channel, and removing blood stasis has the effect of microcirculation improvement.(the same 2. 161 pages)
Agkistrodon: nature and flavor are sweet, salty, warm, return Liver Channel, and dispelling, collateral-activating is favus malignant boil key medicine.(the same 2. 87 pages)
Scorpio: nature and flavor suffering, flat, return Liver Channel, the detoxicating and resolving stagnation of pathogens removing obstruction in the collateral to relieve pain, it is deep to wear muscle, removes the wind effect by wetting.(the same 2. 202 pages)
Radix Aconiti Lateralis Preparata: nature and flavor suffering, heat, GUIXIN, kidney, spleen channel, it is supporing yang to mend fire, and dispersing cold for relieving pain is controlled the cold weak effect of beriberi.(the same 2. 108 pages)
Placenta Hominis: nature and flavor are sweet, salty, warm, return lung, liver, kidney channel, mend smart, nourish blood, QI invigorating.(the same 2. 228 pages)
Sanguis Draxonis: nature and flavor are sweet, salty, flat, GUIXIN, Liver Channel, and hemostasia and promoting granulation is held back skin ulcer, the promoting blood circulation to remove blood stasis pain relieving.(the same 2. 274 pages)
The Radix Astragali: sweet, the tepor of nature and flavor, return the spleen lung meridian, tonifying Qi and lifting yang, promoting pus discharge and tissue regeneration strengthening contains saccharide, choline etc., has antithrombotic to form, improve the effect (the same 1. 130 pages) of cutaneous circulation
All medicines are synthetic, heat-clearing and toxic substances removing, and blood circulation promoting and blood stasis dispelling, promoting tissue regeneration and ulcer healing plays antiinflammatory, improves hemorheology, improves the effect of blood samples of patients circulation, thereby reaches the purpose of curing thromboangiitis obliterans.
Motherland's medical science has absorbed the organic conception theory of mutual generation of five phases restriction or checking relation in five elements in the Chinese ancient philosophy, think and on physiology and pathology, have confidential relation between the vital organs of the human body, this cacosplanchnia often causes the disease of other internal organs, the disease of other internal organs also can cause the pathological changes of these internal organs, and internal organs and extremity nine orifices are closely related on pathogenesis, various paathogenic factors interact, and finally cause the function disorder, disorder of QI and blood and disease takes place.Thromboangiitis obliterans belongs to " necrosis " category in the traditional Chinese medical science, due to, deficiency of the liver and kindey strong mainly due to temper, cold-damp invasion and attack, the venation that stagnates.Spleen kidney yang QI-insufficiency can not the replenishing vital QI with drugs of warm nature extremity, and the summer is felt the heresy of the cold-damp that falls, coagulation of QI-blood then, meridians check, stagnation of QI and blood may bring about pain, the extremity QI and blood is not filled, and loses in moistening fosterly, and then skin and flesh is withered withered not flourish, deficiency of the liver and kindey, the strongly fragrant heat-transformation of a specified duration of cold-evil, noxious dampness contamination, the venation impatency, limb not depletion of blood is supported, and causes burned black necrosis, very then comes off.Pain is wasting QI-blood for a long time, causes QI and blood deficiency.
Chinese patent medicine of the present invention is a starting point with warming YANG to expel cold, promoting blood circulation to remove obstruction in the collateral, heat-clearing and toxic substances removing.At first set about from kidney warming and yang invigorating, medicinal Radix Aconiti Lateralis Preparata, Placenta Hominis, Radix Aconiti Lateralis Preparata are gone into the spleen kidney channel, the sun of energy warming the spleen kidney, and dispersing cold for relieving pain, Placenta Hominis are returned the Liver and kidney warp, energy nourishing blood and invigorating qi, the warm logical foster extremity that moisten.The cold-evil stagnates, and QI and blood is obstructed, and then limbs pain is just used medicines such as Semen Persicae, Flos Carthami, Rhizoma Chuanxiong, Radix Polygoni Ciliinerve, the effect of playing promoting blood circulation, dredging meridian and relieving pain altogether unbearably.Poison is accumulate in the strongly fragrant heat-transformation of a specified duration of cold-evil, and evil poison contamination adds with Flos Lonicerae, Herba Patriniae, Herba Violae, with heat-clearing and toxic substances removing, and detumescence and apocenosis.More help with Agkistrodon, Scorpio expel wind to dredge collateral, eliminating stagnation disappears bitterly.The blood supply of limbs depletion of blood, and cause burned black necrosis, square with Sanguis Draxonis, promoting tissue regeneration and ulcer healing, eliminating stasis to stop pain.The disease of QI and blood deficiency appears in the sick impairment of QI of consumption for a long time blood, and heavily mend and instead easily stay heresy, thus with the Radix Astragali, Radix Angelicae Sinensis, make gas prosperous capable with short blood, blood stasis dispelling and just not hindering, the particularly Radix Astragali one thing energy evacuation of pus pain relieving, the hemopoietic of invigorating blood circulation, expelling the toxic substance from the body with tonic carbuncle of yin nature are persons particularly liable to develop skin infection's panacea in fact.All medicines share, and YIN-cold must be loose, and QI and blood must be logical, and are eliminating evil and just do not hinder, and it is dense that QI invigorating helps arranging, treating both the principal and secondary aspects of a disease, and cold and heat decompose, and all diseases will cancellation.
For showing the curative effect of Chinese patent medicine of the present invention, Chinese patent medicine of the present invention has been carried out the clinical comparison test.According to statistics, test group is totally 180 examples, wherein: male 127 examples, women 53 examples, the age is at 22-67 between year, 42 years old mean age, medical history 8 months-3 years, average 1.6 years, Therapeutic Method was for taking Chinese patent medicine of the present invention, each 1 ball, every day 3 times, per 15 days was 1 course of treatment, the mean treatment time was 14 courses of treatment; Matched group is totally 186 examples, wherein: male 19 examples, women 67 examples, the age is between 19-62 year, medical history 6 months-1.9 years, average 1.2 years, Therapeutic Method was for taking Western medicine, and as Ai Lasulin, the sour sheet etc. that looses, every day 3 times, the mean treatment time is 8 months.And it is as follows to formulate criterion of therapeutical effect:
Recovery from illness: transference cure, dorsal artery of foot or posterior tibial artery are beaten and are recovered normal, and the position test transfers feminine gender to, recovers former work, follows up a case by regular visits to 1-3, does not have recurrence.
Produce effects: clinical symptoms significantly alleviates, and rest pain and intermittent claudication disappear, and suffers from limb color of the leather and temperature and before is clearly better, and the more preceding obvious improvement of beating of instep and posterior tibial artery can be engaged in light work.
Take a turn for the better: the improvement of having beaten of pain relief, but still have slight rest pain, instep and posterior tibial artery.
Invalid: symptom and sign do not have the improver.
The upright shelves of warp stay to be looked into and follow up survey, and carries out the statistical analysis contrast, and statistical result is as follows:
Table 1, test group curative effect situation
2, matched group curative effect situation
From above-mentioned clinical treatment contrast test, picked at random 2 examples are further to show the therapeutic effect of Chinese patent medicine of the present invention.
Wu Xiulun, man, 49 years old, Ma Lou township, Taiqian County, Henan Province Wu Lou people from village, precious at the beginning of calendar year 2001 is to suffer from thromboangiitis obliterans to have a surplus in 1 year, invalid through multi-treatment, the inventor locates to seek medical advice July calendar year 2001, the atrophy of Ipsilateral muscle of leg, and instep portion skin is brown-black, instep portion arteriopalmus disappears, and halluces has 2 * 2 centimetres of depression ulcer, and the skin ulcer face has more purulent secretion, pain increases severely, hold up and turn and go, about 50 meters of every walkings along the street, pain is led capable shank, night, the pain increased, take Chinese patent medicine of the present invention, early, in, respectively obey 1 ball evening, 15 days was 1 course of treatment, take medicine through 5 courses of treatment, around pain relief, the wound surface scarlet granulation that reveals, wound surface and central authorities be the point-like healing.Continuation clothes Chinese patent medicine of the present invention is totally 16 courses of treatment, the pain complete obiteration, and ulcer all heals, and recovery from illness is followed up a case by regular visits to, so far recurrence.
Gu Guangxiang, the man, 47 years old, Yanggu County Da Bu township secondary school teachers, Ipsilateral instep portion skin is livid purple color, the obvious atrophy of muscle of leg, instep portion arteriopalmus disappears.Instep, right side portion and five toe pain were had a surplus as cutting in 8 months, and night, unable to fall asleep often bent over to sit with one's arms about one's knees all night, and walking along the street is born a heavy burden, and the pain increased.Be diagnosed as thromboangiitis obliterans by certain hospital attached to a medical college, hospitalization, well are done the artery bypass art, and be invalid.In August, 1999, oral medicine of the present invention, every day 3 times, each 1 ball, per 15 days was 1 course of treatment, take medicine 4 courses of treatment, pain relief, instep portion skin color has clear improvement, and continues to obey 12 courses of treatment by former side, and recovery from illness is followed up a case by regular visits to, so far recurrence.
Below in conjunction with most preferred embodiment Chinese patent medicine of the present invention is described in further detail.
Get Radix Astragali 30g, Agkistrodon 10g, Scorpio 6g, Rhizoma Dioscoreae Bulbiferae 12g, Flos Carthami 11g, Semen Persicae 15g, Rhizoma Chuanxiong 12g, Radix Paeoniae Rubra 12g, Flos Lonicerae 20g, Placenta Hominis 20g, Radix Angelicae Sinensis 20g, Radix Cyathulae 12g, Hirudo 6g, Radix Glycyrrhizae 12g, Radix Aconiti Lateralis Preparata 6g, Radix Scrophulariae 15g, Radix Salviae Miltiorrhizae 20g, Semen Coicis 20g, Caulis Spatholobi 12g, Eupolyphaga Seu Steleophaga 12g, Sanguis Draxonis 62, Olibanum 9z, Herba Violae 20g, Herba Patriniae 20g, with the said medicine mix homogeneously, grind to form smalls, thin square-bottomed bamboo basket sieving, make honeyed pill, every ball 9g, each 1 ball, every day 3 times, 15 days is 1 course of treatment, state of an illness weight person serve on 16-23 the course of treatment, can effectively treat thromboangiitis obliterans.
Claims (2)
1, a kind of Chinese patent medicine for the treatment of thromboangiitis obliterans, it is characterized in that it is made by the following weight Chinese medicinal raw materials: Radix Astragali 30-50 part, Agkistrodon 6-15 part, Scorpio 2-6 part, Rhizoma Dioscoreae Bulbiferae 10-20 part, Flos Carthami 6-12 part, Semen Persicae 12-20 part, Rhizoma Chuanxiong 10-15 part, Radix Paeoniae Rubra 10-15 part, Flos Lonicerae 20-30 part, Placenta Hominis 15-20 part, Radix Angelicae Sinensis 10-30 part, Radix Cyathulae 10-20 part, Hirudo 3-6 part, Radix Glycyrrhizae 9-12 part, Radix Aconiti Lateralis Preparata 6-8 part, Radix Scrophulariae 10-20 part, Radix Salviae Miltiorrhizae 20-40 part, Semen Coicis 20-30 part, Caulis Spatholobi 12-15 part, Eupolyphaga Seu Steleophaga 12-15 part, Sanguis Draxonis 6-9 part, Olibanum 5-9 part, Herba Violae 20-40 part and Herba Patriniae 12-20 part.
2, Chinese patent medicine as claimed in claim 1 is characterized in that wherein the weight proportion of each raw material is: Radix Astragali 30g, Agkistrodon 10g, Scorpio 6g, Rhizoma Dioscoreae Bulbiferae 12g, Flos Carthami 12g, Semen Persicae 15g, Rhizoma Chuanxiong 12g, Radix Paeoniae Rubra 12g, Flos Lonicerae 20g, Placenta Hominis 20g, Radix Angelicae Sinensis 20g, Radix Cyathulae 12g, Hirudo 6g, Radix Glycyrrhizae 12g, Radix Aconiti Lateralis Preparata 6g, Radix Scrophulariae 15g, Radix Salviae Miltiorrhizae 20g, Semen Coicis 20g, Caulis Spatholobi 12g, Eupolyphaga Seu Steleophaga 12g, Sanguis Draxonis 62, Olibanum 9z, Herba Violae 20g, Herba Patriniae 20g.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021357390A CN1211108C (en) | 2002-10-25 | 2002-10-25 | Chinese patent drug for treating thrombus obliterating angiitis |
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| Application Number | Priority Date | Filing Date | Title |
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| CNB021357390A CN1211108C (en) | 2002-10-25 | 2002-10-25 | Chinese patent drug for treating thrombus obliterating angiitis |
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Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101011493B (en) * | 2007-01-16 | 2010-12-08 | 李丰举 | Angiitis granule and its preparation method |
| CN101199658B (en) * | 2007-12-19 | 2012-07-18 | 李华君 | Chinese medicine compound for oral administration for treating vasculitis |
| CN101380391B (en) * | 2008-09-11 | 2012-05-23 | 刘湘秋 | Traditional Chinese medicine external application paste for treating angiitis |
| CN101711813B (en) * | 2009-11-11 | 2012-01-11 | 宋爱民 | Traditional Chinese medicine pill for treating vasculitis |
| CN102406743B (en) * | 2011-11-23 | 2015-06-24 | 朱法存 | Traditional Chinese preparation for treating cerebral thrombosis |
| CN104666780A (en) * | 2015-02-10 | 2015-06-03 | 青岛市中心医院 | Traditional Chinese medicinal preparation for treating thromboangiitis obliterans |
| CN104800302A (en) * | 2015-03-30 | 2015-07-29 | 奚济孝 | Externally applied plaster for treating thromboangiitis obliterans and preparation method |
| CN105709155A (en) * | 2016-05-03 | 2016-06-29 | 魏忠 | Traditional Chinese medicine for treating thromboangiitis obliterans |
| CN106138702A (en) * | 2016-09-12 | 2016-11-23 | 防城港思创信息技术有限公司 | Inflammation diminishing and blood circulation promoting soup for thrombophlebitis |
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