CN101066335B - Chinese medicine for treating thromboangiitis obliterans and phlebitis and its preparation method - Google Patents

Chinese medicine for treating thromboangiitis obliterans and phlebitis and its preparation method Download PDF

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CN101066335B
CN101066335B CN2007100157987A CN200710015798A CN101066335B CN 101066335 B CN101066335 B CN 101066335B CN 2007100157987 A CN2007100157987 A CN 2007100157987A CN 200710015798 A CN200710015798 A CN 200710015798A CN 101066335 B CN101066335 B CN 101066335B
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phlebitis
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thromboangiitis obliterans
treatment
chinese patent
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CN101066335A (en
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张连仁
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Abstract

The present invention relates to Chinese medicine technology, and is especially one kind of Chinese medicine for treating throboangiitis obliterans and phlebitis and its preparation process. The Chinese medicine is prepared with figwort root, peach kernel, pangolin scale, earthworm, red sage and other seven kinds of Chinese medicinal materials in certain weight proportion, and through soaking in spirit, decocting and bottling. It has high effective rate and curative rate of treating throboangiitis obliterans and phlebitis and its preparation process.

Description

A kind of treatment thromboangiitis obliterans, phlebitis Chinese patent medicine and preparation method thereof
One, technical field
The present invention relates to a kind of treatment thromboangiitis obliterans, phlebitis Chinese patent medicine and preparation method thereof, belong to treatment vasculitis, phlebitis Chinese patent drug technique field.
Two, background technology
At present, treatment thromboangiitis obliterans, phlebitis adopt operative treatment, wound are arranged, to bring painful big of patient and therapeutic effect is undesirable; The employing Drug therapy, also not effective especially at present medicine.
Three, summary of the invention
The object of the present invention is to provide a kind ofly can overcome the defective that prior art exists, and effective percentage reaches more than 90%, treatment thromboangiitis obliterans more than 45% of cure rate, phlebitis Chinese patent medicine and preparation method thereof.
The present invention is based on motherland's medical science to thromboangiitis obliterans and thrombophlebitis pathogeny, become just to execute and control and further to the modern pharmacology exploratory development, it is closely related etc. to think that the vital organs of the human body and extremity nine orifices have.Finally cause function to get muddled, QI-blood circulation is lacked of proper care and is fallen ill.Thromboangiitis obliterans (venation blood stasis symptom) belongs to the traditional Chinese medical science " gangrene of finger or toe " category.Because feelings will internal injury, caused by liver and kidney deficiency and experiencing due to tobacco poisoning, the wound etc., sick at the extremity blood vessels, but substantial connection arranged with Liver and kidney two is dirty.Thrombophlebitis belongs to Chinese medicine categories such as " superficial obstructive phlebitis diseases ", and its cause of disease is the damp and hot evil poison of diseases caused by exogenous pathogenic factor, and feelings will is hindered etc.With damp invasion of lower energizer, qi depression to blood stasis is main pathogenesis to disease at blood vessels.Chinese patent medicine heat-clearing and toxic substances removing of the present invention, blood circulation promoting and dispersing pathogen accumulation, dispelling wind and removing obstruction in the collateral, compensate qi and blood, blood viscosity lowering, vessel softening, increase elasticity are set up the circulation of side limb and are the Therapeutic Principle.Eliminate to suffer from limb ischemia, blood stasis, swelling, pain and fester, sign symptom and reach and cure vasculitic effect.
A kind of treatment thromboangiitis obliterans of the present invention, phlebitis Chinese patent medicine include wine, water and raw material, and according to weight proportion, raw material comprises following component:
Radix Scrophulariae 10-20 part, Semen Persicae 10-16 part, Squama Manis 4-8 part, Pheretima 10-15 part, Radix Salviae Miltiorrhizae 18-25 part, Radix Angelicae Sinensis 10-20 part, Scorpio 2-6 part, Herba Violae 10-25 part, 2040 parts of Flos Lonicerae, Radix Astragali 40-60 part, Oletum Trogopterori 10-16 part, Bungarus Parvus 2-6 part, the weight proportion of wine, water, raw material are that 500-800 part wine is joined 300-600 part water, join 150-200 part raw material.
A large amount of Traditional Chinese medical theory and modern medicine studies prove that each composition pharmacological and formulation ratio thereof carry out a large amount of exploratory developments in the Chinese patent medicine of the present invention, and it is concluded active ingredient and acts on as follows:
Radix Scrophulariae: nature and flavor hardship, sweet, salty, cold, return the lung kidney channel, contain Radix Scrophulariae glycoside, alkaloid etc., the heat clearing away YIN nourishing, detoxicating and resolving stagnation of pathogens has inhibitory action to bacillus pyocyaneus.
Semen Persicae: nature and flavor hardship, sweet, flat, GUIXIN liver large intestine channel contains amygdalin, fatty wet goods, and removing blood stasis has significant anticoagulant effect.Cure mainly: stasis, wind illness, hectic fever due to YIN-deficiency, cold and heat, pain etc.
Radix Salviae Miltiorrhizae: the nature and flavor hardship, be slightly cold, the GUIXIN Liver Channel, contain TANSHINONES etc.The expansion peripheral vessels, anticoagulation, anti-platelet aggregation, conscience blood part has blood circulation promoting and blood stasis dispelling, cooling blood and relieving pain, clearing heat for detumescence etc.
Radix Angelicae Sinensis: nature and flavor are sweet, hot, warm, return liver heart spleen channel, contain volatile oil, alkaloid, have and invigorate blood circulation, enrich blood, and Fibrinogen is descended, and can enrich blood, effects such as cold expelling, pain relieving.
Pheretima: nature and flavor are salty, cold, return the Liver and kidney lung meridian, and property is apt to away scurry, current meridians, effects such as expelling cold and dampness.
Squama Manis: the big gun Squama Manis: nature and flavor are salty, and flavor is cold, returns liver stomach warp, interior logical internal organs, the effects such as meridians, detumescence and apocenosis of passing through inside.
Bungarus Parvus: nature and flavor are sweet, salty, warm, return Liver Channel, effects such as dispelling, collateral-activating.
Scorpio: nature and flavor suffering, flat, return Liver Channel, dehumidifying removes wind, detoxicating and resolving stagnation of pathogens, effects such as removing obstruction in the collateral to relieve pain, sore swollen toxin.
Flos Lonicerae: nature and flavor are sweet, cold, return lung, stomach, large intestine channel, contain cyclohexanhexanol, and the reseda flavin has the broad-spectrum antibacterial action.
The Radix Astragali: sweet, the tepor of nature and flavor, return spleen, lung meridian, contain saccharide, choline, antithrombotic effect is arranged, promoting pus discharge and tissue regeneration strengthening improves sanguimotor effect.
Herba Violae: nature and flavor hardship, suffering, cold, the GUIXIN Liver Channel, heat-clearing and toxic substances removing contains glycoside, flavonoid etc., and the broad-spectrum antibacterial action is arranged.
Oletum Trogopterori: nature and flavor are sweet, warm, return Liver Channel, go into liver blood part, promoting blood circulation and stopping pain, promoting blood circulation etc.
All medicines synthesize Synergistic treatment: with heat-clearing and toxic substances removing, and blood circulation promoting and blood stasis dispelling, anti-inflammation detumescence improves hemorheology, and promoting tissue regeneration and ulcer healing is cured vasculitic purpose thereby reach.
A kind of manufacture method for the treatment of thromboangiitis obliterans, phlebitis Chinese patent medicine of the present invention may further comprise the steps:
At first, get each component mix homogeneously according to weight proportion;
Then, soaked 30-60 minute with drinks;
Carried out fried back sub-bottling fried 40-80 minute.
Instructions of taking: every day three times is for oral administration, obeys 30 milliliters at every turn, and every day 3 times, one month is a course of treatment, the shortest 2 courses of treatment, the longest 6 courses of treatment, average 3 courses of treatment, can effectively treat thromboangiitis obliterans, phlebitis.
A kind of treatment thromboangiitis obliterans of the present invention, phlebitis Chinese patent medicine, promoting blood circulation to remove obstruction in the collateral, heat-clearing and toxic substances removing, damp eliminating, cold setting about, the side is with medicines such as Semen Persicae, Radix Salviae Miltiorrhizae, gathers promoting blood circulation to restore menstrual flow, removing obstruction for relieving pain altogether.Cold-damp pathogenic heat poison adds Flos Lonicerae, Herba Violae, heat-clearing and toxic substances removing, detumescence, evacuation of pus etc.Agkistrodon, Scorpio expel wind to dredge collateral, eliminating stagnation disappear bitterly.Oletum Trogopterori eliminating stasis to stop pain, clearing heat for calming endogenous wind, current meridians are selected Pheretima etc. for use.QI and blood deficiency, so with the Radix Astragali, Radix Angelicae Sinensis, and Radix Angelicae Sinensis, the Radix Astragali are invigorated blood circulation, hemopoietic, pain relieving, and QI and blood must be logical, not eliminating evil just the wound, and treating both the principal and secondary aspects of a disease, cold and heat decompose, all card cancellations.A kind of treatment thromboangiitis obliterans of the present invention, phlebitis Chinese patent medicine, effective percentage is more than 90%, and obvious effective rate is more than 75%, and cure rate is more than 45%.
Four, the specific embodiment
Describe the present invention in detail with embodiment below, but these embodiment must not be interpreted as the limitation of the present invention that goes up in all senses.
Embodiment 1
A kind of treatment thromboangiitis obliterans, phlebitis Chinese patent medicine, according to weight proportion, raw material comprises following component: 10 parts of Radix Scrophulariae, 10 parts in Semen Persicae, 4 parts of Squama Manis, 10 parts of Pheretimas, 18 parts of Radix Salviae Miltiorrhizaes, 10 parts of Radix Angelicae Sinensis, 2 parts of Scorpios, 10 parts of Herba Violaes, 20 parts of Flos Lonicerae, 40 parts of the Radixs Astragali, 10 parts of Oletum Trogopteroris, 2 parts of Bungarus Parvus, the weight proportion of wine, water, raw material are that 500 portions of wine are joined 300 parts of water, join 150 parts of raw materials.
Manufacture method may further comprise the steps: at first, get each component mix homogeneously according to weight proportion; Then, soaked 30-60 minute with drinks; Carried out fried back sub-bottling fried 40-80 minute.
Embodiment 2
Present embodiment 2 is with the difference of embodiment 1
A kind of treatment thromboangiitis obliterans, phlebitis Chinese patent medicine, according to weight proportion, raw material comprises following component: 20 parts of Radix Scrophulariae, 16 parts in Semen Persicae, 8 parts of Squama Manis, 15 parts of Pheretimas, 25 parts of Radix Salviae Miltiorrhizaes, 20 parts of Radix Angelicae Sinensis, 6 parts of Scorpios, 25 parts of Herba Violaes, 40 parts of Flos Lonicerae, 60 parts of the Radixs Astragali, 16 parts of Oletum Trogopteroris, 6 parts of Bungarus Parvus, the weight proportion of wine, water, raw material are that 800 portions of wine are joined 600 parts of water, join 200 parts of raw materials.
Embodiment 3
Present embodiment 3 is with the difference of embodiment 1
A kind of treatment thromboangiitis obliterans, phlebitis Chinese patent medicine, according to weight proportion, raw material comprises following component: 15 parts of Radix Scrophulariae, 13 parts in Semen Persicae, 6 parts of Squama Manis, 12 parts of Pheretimas, 21 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Angelicae Sinensis, 4 parts of Scorpios, 17 parts of Herba Violaes, 30 parts of Flos Lonicerae, 50 parts of the Radixs Astragali, 13 parts of Oletum Trogopteroris, 4 parts of Bungarus Parvus, the weight proportion of wine, water, raw material are that 650 portions of wine are joined 450 parts of water, join 160 parts of raw materials.
Embodiment 4
Present embodiment 4 is with the difference of embodiment 1
A kind of treatment thromboangiitis obliterans, phlebitis Chinese patent medicine, according to weight proportion, raw material comprises following component: 10 parts of Radix Scrophulariae, 18 parts in Semen Persicae, 7 parts of Squama Manis, 15 parts of Pheretimas, 20 parts of Radix Salviae Miltiorrhizaes, 10 parts of Radix Angelicae Sinensis, 6 parts of Scorpios, 20 parts of Herba Violaes, 32 parts of Flos Lonicerae, 53 parts of the Radixs Astragali, 13 parts of Oletum Trogopteroris, 3 parts of Bungarus Parvus, the weight proportion of wine, water, raw material are that 800 portions of wine are joined 350 parts of water, join 180 parts of raw materials.
For showing the curative effect of Chinese patent medicine of the present invention, carried out clinical comparison.According to statistics, test group is totally 200 many cases, wherein male 137 examples, women 67 examples, the age between 23-76,46 years old mean age, medical history 2 months-3 years.Therapeutic Method is the fried Chinese medicine of wine of taking invention, and each 30 milliliters, every day 3 times, one month is a course of treatment, the shortest 2 courses of treatment, the longest 6 courses of treatment, average 3 courses of treatment.
The formulation criterion of therapeutical effect is as follows:
Recovery from illness: transference cure, turning out cloudy property of position test, it is normal that dorsal artery of foot recovers, and the phlebitis lower limb swell and ache and also recover fully, recover former work, follow up a case by regular visits to 2-3 and do not have recurrence.
Produce effects: clinical symptoms obviously alleviates, and intermittent claudication disappears, and suffer from limb color of the leather temperature and be clearly better, lower limb disappearances of swelling and ache, instep, posterior tibial artery fluctuate and are clearly better, and can be engaged in general work.
Take a turn for the better: pain relief, lower limb swell and ache and are clearly better, but ask night and still have rest pain, but can fall asleep, and the dorsal artery of foot pollex slightly takes a turn for the better.
Invalid: symptom and sign does not have improvement and takes a turn for the better.
Table 1: test group 1 curative effect situation
Standard curative effect number Invalid Take a turn for the better Produce effects Recovery from illness
Total number of persons Number Number Number Number
200 7 3.5% 23 11.5% 60 30% 110 55%
Table 2: test group 2 curative effect situations
From above-mentioned clinical patient treatment contrast test, choose the therapeutic effect that 2 examples further show Chinese patent medicine of the present invention.
Case 1: Lan Haozheng, man, 49 years old, the accounting of Xin Zhuan town, Zhaoyuan City, Shandong Province supply and marketing cooperative, be diagnosed as thromboangiitis obliterans in Yantai hospital in April, 2003, and the smelting of being in hospital is treated, prepare to implement amputation, the inventor locates to seek medical advice in May, 2003, the atrophy of Ipsilateral Calf muscle, the instep is brown-black, the dorsal artery of foot disappearance of beating, 2 * 3 centimetres of ulcer of thumb are suppurated, pain is heavier, can not walk, night, the pain increased can not fall asleep, and takes Chinese patent medicine preparation of the present invention, in 40 milliliters, the evening 50 milliliters, pain obviously alleviates after 7 days, one the course of treatment wound surface grow scarlet granulation, 2 the pain complete obiterations course of treatment, all healings and fully recovering of 4 the ulcer course of treatment.
Case 2: Zhang Jisheng, the man, 62 years old, the worker of Yantai Port Office, sub-district, Zhifu District letter home, Yantai City, at the Yantai hospital diagnosis is thrombophlebitis, does not take a turn for the better left lower extremity III ~ C pitting edema through wheat harvesting period treatment, skin is purplish red, the red and swollen tenderness of great saphenous vein many places lump, difficulty in walking can not be worked, the aggravation of movable back, early 30 milliliters of oral medicine of the present invention every days, 30 milliliters of noons, 40 milliliters of evenings, swell and ache after three days and be clearly better, can walk, return to one's perfect health 2 courses of treatment, follows up a case by regular visits to so far not recurrence.

Claims (3)

1. treat thromboangiitis obliterans, phlebitis Chinese patent medicine for one kind, it is characterized in that:
According to weight proportion, raw material is by Radix Scrophulariae 10-20 part, Semen Persicae 10-16 part, Squama Manis 4-8 part, Pheretima 10-15 part, Radix Salviae Miltiorrhizae 18-25 part, Radix Angelicae Sinensis 10-20 part, Scorpio 2-6 part, Herba Violae 10-25 part, Flos Lonicerae 20-40 part, Radix Astragali 40-60 part, Oletum Trogopterori 10-16 part, Bungarus Parvus 2-6 part is formed, the weight proportion of wine, water, raw material is that 500-800 part wine is joined 300-600 part water, joins 150-200 part raw material.
2. according to the described a kind of manufacture method for the treatment of thromboangiitis obliterans, phlebitis Chinese patent medicine of claim 1, it is characterized in that may further comprise the steps:
At first, get each component mix homogeneously according to weight proportion;
Then, soak with drinks;
Carry out fried, fried back sub-bottling.
3. according to the described a kind of manufacture method for the treatment of thromboangiitis obliterans, phlebitis Chinese patent medicine of claim 2, it is characterized in that the drinks soak time is 30-60 minute, fried 40-80 minute.
CN2007100157987A 2007-06-01 2007-06-01 Chinese medicine for treating thromboangiitis obliterans and phlebitis and its preparation method Active CN101066335B (en)

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Publication number Priority date Publication date Assignee Title
CN105709187A (en) * 2016-01-29 2016-06-29 王延刚 Traditional Chinese medicinal composition for treating extremity superficial thrombophlebitis

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1679843A (en) * 2005-01-27 2005-10-12 朱腾月 Oral medicine for treating thromboangitis obliterans
CN101053632A (en) * 2006-04-13 2007-10-17 吴希文 Traditional Chinese medicine for treating thromboangitis obliterans

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1679843A (en) * 2005-01-27 2005-10-12 朱腾月 Oral medicine for treating thromboangitis obliterans
CN101053632A (en) * 2006-04-13 2007-10-17 吴希文 Traditional Chinese medicine for treating thromboangitis obliterans

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