CN1679843A - Oral medicine for treating thromboangitis obliterans - Google Patents

Oral medicine for treating thromboangitis obliterans Download PDF

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CN1679843A
CN1679843A CN 200510042054 CN200510042054A CN1679843A CN 1679843 A CN1679843 A CN 1679843A CN 200510042054 CN200510042054 CN 200510042054 CN 200510042054 A CN200510042054 A CN 200510042054A CN 1679843 A CN1679843 A CN 1679843A
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radix
processed
herba
medicine
olibanum
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CN100341545C (en
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朱腾月
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Abstract

A Chinese medicine for treating thromboangitis obliterans is prepared proportionally from 28 Chinese-medicinal materials including Chinese angelica root, Chuan-xiong rhizome, red peony root, red sage root, etc.

Description

The oral medicine of treatment thromboangiitis obliterans
Technical field
Medicine of the present invention belongs to traditional Chinese medical science powder technical field, is a kind of oral medicine for the treatment of thromboangiitis obliterans specifically.
Background technology
Thromboangiitis obliterans is a kind of inflammation and occlusive disease that involves blood vessel.The medium and small artery and vein of main invasion and attack extremity, especially lower limb.The cause of disease of primary disease is not understood as yet fully.Can only say and be caused, long-term smoking, cold stimulation by multiple factor; self hormonal regulation; immune dysfunction or nervus vasculairs insufficiency of accommodation, the constriction to involved vessels is hardened is non-infectious holostrome inflammation; in thrombosis is arranged; be extensive fibrosis around blood vessel wall reaches, suffer from limb ischemia palor, send out cool; Zhou Jing dwindles, of flaccid muscles, atrophy.Later stage is because of ischemic limb gangrene, ulcer.Patient's pain is painful unusual.Operate as normal and life have been had a strong impact on.
To the treatment of primary disease, doctor trained in Western medicine adopts more oral, instillation vasodilation is as hyoscyamine, kallidinogenase; Thrombolytic agent, as urokinase, streptokinase, or therapy such as operation.The patient suffering is big, and the expense height influences operate as normal and life, and very easily recurrence.The traditional Chinese medical science adopts YANGHE TANG more, Angelicae Decoction for Activating Blood, and the way that SIMIAOYONGAN TANG etc. are oral, specific aim are not strong, and treatment time is long, cures the symptoms, not the disease, and effect is not good.
The object of the present invention is to provide a kind of oral medicine for the treatment of thromboangiitis obliterans.But warming YANG to expel cold, blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain, heat-clearing and toxic substances removing, putrefaction-removing granulation-promoting.Thereby reach the purpose of treatment thromboangiitis obliterans.Medicine of the present invention is formulated by pure Chinese medicine, and patient's taking convenience is evident in efficacy, is not easy to obtain after healing and sends out.
Summary of the invention
Solution of the present invention is based on pathogenetic understanding and the Therapeutic Principle of motherland to thromboangiitis obliterans.Study with reference to modern medicines, utilization is nourished blood, is invigorated blood circulation, warming YANG, collateral dredging, spasmolytic, pain relieving, heat-clearing and toxic substances removing, benefiting qi and nourishing blood class medicine are formulated, blood viscosity lowering is promptly arranged, improve the effect of hemorheology, the LBF of increasing amount is arranged again, improve the microcirculatory effect of limbs, can obviously improve symptoms such as of flaccid muscles, atrophy, extremity gangrene, pain, ulcer, reach the purpose of treatment thromboangiitis obliterans.It is formulated by pure Chinese medicine that the present invention treats the oral medicine of thromboangiitis obliterans, without any side effects to human body.
It is as follows that the present invention treats the prescription and the weight proportion of oral medicine of thromboangiitis obliterans:
Radix Ilicis Pubescentis 60-70 part, Radix Angelicae Sinensis 15-20 part, Radix Rehmanniae 20-25 part, Rhizoma Chuanxiong 10-15 part, Radix Paeoniae Rubra 15-20 part, Radix Salviae Miltiorrhizae 20-25 part, Flos Carthami 10-15 part, Semen Persicae 10-15 part, Herba Asari 3-5 part, Olibanum (processed) 10-15 part, Myrrha (processed) 10-15 part, Caulis Spatholobi 30-35 part, Hirudo 10-15 part, Scolopendra 10-15 part, Pheretima 12-15 part, Scorpio 3-5 part, Squama Manis 3-5 part, Agkistrodon 3-5 part, Herba Ephedrae 10-15 part, Ramulus Cinnamomi 10-15 part, Cornu Cervi Degelatinatum 15-20 part, gun additioner 30-40 part, Radix Astragali 30-35 part, Radix Codonopsis 15-20 part, Flos Lonicerae 60-90 part, Radix Scrophulariae 60-70 part, Herba Violae 30-40 part, Radix Glycyrrhizae 15-20 part.
Use the above-mentioned prescription of medicine of the present invention, the treatment thromboangiitis obliterans, taking convenience, evident in efficacy, effective percentage 96%, cure rate reaches 84%.
Drug action mechanism of the present invention is as follows:
The antipyretic and antidotal type medicine is in the medicine of the present invention: Flos Lonicerae, Radix Glycyrrhizae, Radix Scrophulariae, Herba Violae; The class of invigorating blood circulation medicine is: Radix Ilicis Pubescentis, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, the Radix Rehmanniae, Flos Carthami, Semen Persicae, Caulis Spatholobi, Radix Paeoniae Rubra; Dispelling, collateral-activating class medicine is: Hirudo, Pheretima, Scolopendra, Scorpio, Agkistrodon, Squama Manis; Warming YANG class medicine is: Cornu Cervi Degelatinatum, Herba Ephedrae, Ramulus Cinnamomi, gun additioner, Herba Asari; Pain relieving class medicine is: Olibanum (processed), Myrrha (processed); The QI invigorating medicine is: the Radix Astragali, Radix Codonopsis.
Prove according to Traditional Chinese medical theory and modern medicine study, the nature and flavor of various composition medicines in the Chinese patent medicine of the present invention, return through and useful effect as follows:
Radix Ilicis Pubescentis: mildly bitter flavor is sweet, property is flat, nontoxic, goes into heart spleen channel.Effect (see " Chinese medicine voluminous dictionary " 442 pages, the new medical college in Jiangsu is compiled, and Shanghai science tech publishing house publishes in May, 1986) with heat-clearing and toxic substances removing, blood circulation and channel invigorating.
Radix Angelicae Sinensis: sweet in the mouth suffering, warm in nature, go into the heart, liver, spleen channel.Having enriches blood invigorates blood circulation, and moisturizes the effect (the same 877 pages) of pain relieving.
The Radix Rehmanniae: bitter in the mouth, cool in nature, go into liver, kidney channel.The effect that have YIN nourishing, nourishes blood (the same 75 pages).Rhizoma Chuanxiong: acrid in the mouth, warm in nature, go into liver, gallbladder meridian.Effect (the same 221 pages) with activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness, promoting blood circulation and stopping pain.
Radix Paeoniae Rubra: sour in the mouth hardship, cool in nature, go into liver, spleen channel.Effect (the same 1095 pages) with clots absorbing, pain relieving, removing heat from blood detumescence.
Radix Salviae Miltiorrhizae: bitter in the mouth, slightly warm in nature, go into the heart, Liver Channel.Effect (the same 480 pages) with blood circulation promoting and blood stasis dispelling, evacuation of pus, pain relieving.
Flos Carthami: acrid in the mouth, warm in nature, go into the heart, Liver Channel.Effect (the same 993 pages) with promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.
Semen Persicae: bitter but sweet flavor, property are put down, and go into the heart, liver, large intestine channel.Effect (the same 1788 pages) with blood stasis removing and clots absorbing.
Herba Asari: acrid in the mouth, warm in nature, go into lung, kidney channel.Effect (the same 1479 pages) with expelling wind and cold, circulation of qi promoting.
Olibanum: acrid in the mouth hardship, warm in nature, go into the heart, liver, spleen channel.Have regulating qi and activating blood, analgesic therapy, chase after the effect (the same 1380 pages) of poison.
Myrrha: bitter in the mouth, property are put down, and go into Liver Channel.Effect (the same 1168 pages) with diffusing blood and dissolving stasis, subduing swelling and relieving pain.
Hirudo: salty in the mouth hardship, property are flat, poisonous, go into liver, urinary bladder channel.Effect (the same 518 pages) with removing blood stasis, removing blood stasis.
Radix Glycyrrhizae: sweet in the mouth, property are put down, and go into spleen, stomach, lung meridian.Emergency, detoxifcation, coordinating the actions of various ingredients in a prescription (the same 570 pages) are arranged.
Caulis Spatholobi: bitter in the mouth, sweet, warm in nature, go into the heart, spleen two warps.Have invigorate blood circulation, the effect (the same 1207 pages) of Shujin.
Scolopendra: acrid in the mouth, warm in nature, poisonous, go into Liver Channel.Have dispel the wind, the effect (the same 247 pages) of arresting convulsion, counteracting toxic substances, eliminating stagnation.
Scorpio: salty in the mouth, suffering, property are put down, and be poisonous, goes into Liver Channel.Have dispel the wind, the effect (the same 2113 pages) of relieving convulsion, collateral dredging.
Pheretima: salty in the mouth, cold in nature, go into liver, spleen, lung meridian.Heat clearing away, suppressing the hyperactive liver, Zhichuan, (the same 2113 pages) stimulate the menstrual flow.
Agkistrodon: sweet in the mouth, salty, warm in nature, poisonous, liver, spleen channel.Wind-damp dispelling, saturating muscles and bones, jerk (the same 714 pages) of calming the frightened.
Squama Manis: salty in the mouth, cool in nature, go into liver, stomach warp.The routed carbuncle of detumescence is searched wind active (the same 1727 pages).
Cornu Cervi Degelatinatum: salty in the mouth, warm in nature, go into liver, kidney channel.Tonify deficiency, supporing yang (the same 2241 pages).
The Fructus Citri tangerinae branch: acrid in the mouth, sweet, warm in nature, go into urinary bladder channel.Warming the meridian and promoting blood circulation (the same 1772 pages).
Radix Codonopsis: sweet in the mouth, property are put down, and go into spleen channel.Benefit through QI invigorating, (the same 2038 pages) promote the production of body fluid.
The Radix Astragali: sweet in the mouth, slightly warm in nature, go into lung, spleen channel.Benefit is defended consolidating superficial resistance, inducing diuresis to remove edema, invigorating the spleen and replenishing QI (the same 2038 pages).
Herba Ephedrae: acrid in the mouth, hardship, slightly warm in nature, go into lung, urinary bladder channel.But diaphoresis, relieving asthma, diuretic (the same 2223 pages).
Herba Violae: bitter in the mouth, cold in nature, go into the heart, Liver Channel.Clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling (the same 801 pages).
Radix Aconiti Lateralis Preparata: acrid in the mouth, sweet, hot in nature, poisonous, go into the heart, spleen, kidney channel.Recuperating depleted YANG is mended fire, dispelling cold and removing dampness (the same 1191 pages).
Flos Lonicerae: sweet in the mouth, cold nature, go into lung, stomach warp.Heat-clearing and toxic substances removing (the same 1404 pages).
Radix Scrophulariae: bitter in the mouth, salty, cool in nature, go into lung, kidney channel.YIN nourishing, pathogenic fire reducing, relieving restlessness, detoxifcation (the same, 770 pages).
All medicines are synthetic, and heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, warming YANG to expel cold play antiinflammatory, improve sanguimotor effect, thereby reach the purpose of curing thromboangiitis obliterans.
The Chinese medicine traditional theory is thought: have substantial connection between the vital organs of the human body on physiology, influence each other, interact, as the function disorder, cause the body disorder of QI and blood and disease takes place.The thromboangiitis obliterans traditional Chinese medical science belongs to " necrosis " category, claims " thromb angintis and thromboarteriosclerosis " again.Its pathogenic factor is that human body temper is unstrong, deficiency of the liver and kindey, is added with cold-damp and attacks outward, and eating and drinking without temperance is had a liking for the cigarette impairment caused by overstrain, and inducements such as direct stimulation cause QI and blood not smooth, and venation stagnates and forms.Spleen kidney yang QI-insufficiency can not the replenishing vital QI with drugs of warm nature extremity, coagulation of QI-blood then, and meridians check, stagnation of QI and blood may bring about pain, the extremity insufficiency of vital energy and blood loses in moistening fosterly, and then skin and flesh is withered withered not flourish, deficiency of the liver and kindey, heat transformed from stagnated cold, the noxious dampness contamination, the venation obturation, limb tip depletion of blood is supported, and causes burned black necrosis, very then comes off.
Medicine of the present invention is a starting point with heat-clearing and toxic substances removing, warming YANG to expel cold, promoting blood circulation to remove obstruction in the collateral, first-selected Radix Ilicis Pubescentis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Caulis Spatholobi, Flos Carthami, Semen Persicae, Radix Angelicae Sinensis, the Radix Rehmanniae, Radix Paeoniae Rubra, blood circulation promoting and blood stasis dispelling, the Radix Astragali, Radix Codonopsis invigorating the spleen and replenishing QI, the hemopoietic of invigorating blood circulation, the evacuation of pus pain relieving, the Zhi Qiben of meaning; Herba Ephedrae, Ramulus Cinnamomi, Cornu Cervi Degelatinatum, gun additioner cold expelling, Flos Lonicerae, Radix Scrophulariae, Herba Violae, Radix Glycyrrhizae, detoxifcation; Scorpio, Agkistrodon spasmolytic, Hirudo, Scolopendra, Pheretima, Squama Manis collateral dredging; Herba Asari, Olibanum (processed), Myrrha (processed) pain relieving, that calls effects a permanent cure.Treating both the principal and secondary aspects of a disease.Reach monarch, Each performs its own functions, symptomatic treatment in acute condition, relieving the primary symptom in a chronic case, treating both the principal and secondary aspects of a disease.All medicines share, and YIN-cold must be loose, and QI and blood must be logical, not eliminating evil just the wound, and QI invigorating helps evacuation of pus, and cold and heat decompose, and all diseases will cancellation.Reach the purpose of treatment thromboangiitis obliterans.
The specific embodiment
Below in conjunction with embodiment medicine of the present invention is described further.
Embodiment 1: get Radix Ilicis Pubescentis 60g, Radix Angelicae Sinensis 15g, Radix Rehmanniae 20g, Rhizoma Chuanxiong 10g, Radix Paeoniae Rubra 18g, Radix Salviae Miltiorrhizae 25g, Flos Carthami 15g, Semen Persicae 10g, Herba Asari 3g, Olibanum (processed) 10g, Myrrha (processed) 10g, Caulis Spatholobi 30g, Hirudo 10g, Scolopendra 10g, Pheretima 12g, Scorpio 3g, Squama Manis 3g, Agkistrodon 3g, Herba Ephedrae 10g, Ramulus Cinnamomi 10g, Cornu Cervi Degelatinatum 15g, gun additioner 30g.
Cure mainly: the asthenic cold type thromboangiitis obliterans.
Radix Aconiti Lateralis Preparata is concocted in the side: get Radix Aconiti Lateralis Preparata and clean, clear water soaked 12 hours, removed and removed the peel umbilicus, and section adds blister to mouth again and tastes spicy slightly sense for spending.Take out, soaked 1-3 days with ginger decoction, cook then, bake to seventy percent again and do, pour urgent the stir-fry to cigarette of useing force in the pot into and rise, it is degree that little drum splits, and taking-up cools, and is standby.Olibanum is concocted: get the Olibanum of choosing clean and put into pot and fry with slow fire and see slightly to the surface and fusing slightly to be yellow that taking-up cools, and is standby.
The concocting method of Myrrha is identical with Olibanum.
Said medicine is decocted in water for oral dose, and every day, potion was taken at twice, and serveing on 20 is a course of treatment, and state of an illness weight person serve on 5-7 the course of treatment, can effectively treat thromboangiitis obliterans.
Embodiment 2: get Radix Ilicis Pubescentis 60g, Radix Angelicae Sinensis 15g, Radix Rehmanniae 20g, Rhizoma Chuanxiong 10g, Radix Paeoniae Rubra 18g, Radix Salviae Miltiorrhizae 25g, Flos Carthami 15g, Semen Persicae 10g, Herba Asari 3g, Olibanum (processed) 10g, Myrrha (processed) 10g, Caulis Spatholobi 30g, Hirudo 10g, Scolopendra 10g, Pheretima 12g, Scorpio 3g, Squama Manis 3g, Agkistrodon 3g, Radix Astragali 30g, Radix Codonopsis 15g.
Cure mainly: the QIXUELIANGXU type thromboangiitis obliterans.Method for making, instructions about how to take medicine are with embodiment 1.
Embodiment 3: get Radix Ilicis Pubescentis 60g, Radix Angelicae Sinensis 15g, Radix Rehmanniae 20g, Rhizoma Chuanxiong 10g, Radix Paeoniae Rubra 18g, Radix Salviae Miltiorrhizae 25g, Flos Carthami 15g, Semen Persicae 10g, Herba Asari 3g, Olibanum (processed) 10g, Myrrha (processed) 10g, Caulis Spatholobi 30g, Hirudo 10g, Scolopendra 10g, Pheretima 12g, Scorpio 3g, Squama Manis 3g, Agkistrodon 3g, Flos Lonicerae 90g, Radix Scrophulariae 60g, Herba Violae 30g, Radix Glycyrrhizae 15g.
Cure mainly: the heat-toxin type thromboangiitis obliterans.Method for making, instructions about how to take medicine are with embodiment 1.
For showing the curative effect of medicine of the present invention, medicine of the present invention has been carried out the clinical comparison test.According to statistics, the 150 routine patients that treat are divided into test group and matched group, respectively be 75 examples; Male's 50 examples in the test group, women's 25 examples, the age is at 25-69 between year, 47 years old mean age, medical history 6 months-3 years.Therapeutic Method is for taking medicine of the present invention, and every day, potion was taken at twice, and serveing on 20 is a course of treatment, and the mean treatment time is 5 courses of treatment; Male's 48 examples in the contrast, women's 27 examples, the age between 24-69, medical history 6 months-3 years, Therapeutic Method is mainly takes Western medicine, as uses vasodilation, as hyoscyamine, kallidinogenase, thrombolytic agent, as treatments such as urokinase, streptokinases, the mean treatment time is 7 months-1 year.It is as follows to have formulated criterion of therapeutical effect:
Recovery from illness: transference cure, dorsal artery of foot and posterior tibial artery pulse are beaten and are recovered normal, and the position movement test transfers feminine gender to, recovers former work, and have carried out following the tracks of and followed up a case by regular visits to 1-3, no longer recurrence.
Produce effects: clinical symptoms obviously alleviates, and rest pain and intermittent claudication disappear, and suffering from limb color of the leather and surface temperature before has obviously, and instep portion, posterior tibial artery pulse are beaten and before had clear improvement, and can be engaged in than light work.
Take a turn for the better: the improvement of having beaten of pain relief, but still have slight rest pain, instep portion and posterior tibial artery pulse.
Invalid: symptom and sign do not have the improver.
The upright shelves of warp stay to be looked into and follow up survey, and carries out the statistical analysis contrast, and statistical result is as follows:
Table one, test group curative effect situation:
Standard curative effect number Invalid Take a turn for the better Produce effects Recovery from illness
Total number of persons Number ??% Number ????% Number ???% Number ????%
??75 ??3 ??4 ??9 ????12 ??45 ???60 ??63 ????84
Table two, matched group curative effect situation:
Standard curative effect number Invalid Take a turn for the better Produce effects Recovery from illness
Sum Number ????% Number ????% Number ????% Number ????%
??75 ??19 ????25 ??26 ????35 ??23 ????30 ???30 ????40
From above-mentioned clinical treatment contrast test, picked at random 2 examples are further to show the therapeutic effect of medicine of the present invention.
Wu Chunwei, the man, 43 years old, Gao Miaowang township, Yanggu County, Shandong Province Wu Tang people from village, first visit in March, 2000 is nearly a year of thromboangiitis obliterans, and is invalid through multi-treatment, the inventor punishes treatment in May, 2000.The atrophy of patient's Calf muscle, instep portion skin is brown, and instep portion tremulous pulse pollex disappears substantially, and there is ulcer on the surface, and purulent secretion is arranged, and oral account severe pain is handicapped; Take medicine of the present invention, 4 courses of treatment, pain relief, secretions are gradually few, wound surface reveal cerise and healing gradually.Continue clothes the present invention and consolidate 2 courses of treatment, reached the pain complete obiteration, ulcer all heals, and recovery from illness is followed up a case by regular visits to, so far not recurrence.
Song Fujun, man 41 years old, West Lake township, Yanggu County, Shandong Province, the worker, Ipsilateral instep portion skin is purple, and muscle of leg is atrophy, and instep portion arteriopalmus disappears.Left side instep portion pain was had a surplus as cutting in 6 months, night unable to fall asleep, walking along the street is born a heavy burden, the pain increased.Be diagnosed as thromboangiitis obliterans by County Hospital, the hospitalization therapeutic effect is not good, and is invalid substantially.August calendar year 2001, come this drug invention people to punish treatment, 5 courses of treatment, oral medicine of the present invention, pain relief, instep portion skin color has clear improvement, and continues to obey 3 courses of treatment by former side, and recovery from illness is followed up a case by regular visits to, so far recurrence.

Claims (4)

1, a kind of Chinese patent medicine for the treatment of thromboangiitis obliterans is characterized in that it is made by the following weight Chinese medicinal raw materials: Radix Ilicis Pubescentis 60-70 part, Radix Angelicae Sinensis 15-20 part, Radix Rehmanniae 20-25 part, Rhizoma Chuanxiong 10-15 part, Radix Paeoniae Rubra 15-20 part, Radix Salviae Miltiorrhizae 20-25 part, Flos Carthami 10-15 part, Semen Persicae 10-15 part, Herba Asari 3-5 part, Olibanum (processed) 10-15 part, Myrrha (processed) 10-15 part, Caulis Spatholobi 30-35 part, Hirudo 10-15 part, Scolopendra 10-15 part, Pheretima 12-15 part, Scorpio 3-5 part, Squama Manis 3-5 part, Agkistrodon 3-5 part, Herba Ephedrae 10-15 part, Ramulus Cinnamomi 10-15 part, Cornu Cervi Degelatinatum 15-20 part, gun additioner 30-40 part, Radix Astragali 30-35 part, Radix Codonopsis 15-20 part, Flos Lonicerae 60-90 part, Radix Scrophulariae 60-70 part, Herba Violae 30-40 part, Radix Glycyrrhizae 15-20 part.
2, Chinese patent medicine as claimed in claim 1 is characterized in that wherein the weight proportion of each raw material is: Radix Ilicis Pubescentis 60, Radix Angelicae Sinensis 15, the Radix Rehmanniae 20, Rhizoma Chuanxiong 10, Radix Paeoniae Rubra 18, Radix Salviae Miltiorrhizae 25, Flos Carthami 15, Semen Persicae 10, Herba Asari 3, Olibanum (processed) 10, Myrrha (processed) 10, Caulis Spatholobi 30, Hirudo 10, Scolopendra 10, Pheretima 12, Scorpio 3, Squama Manis 3, Agkistrodon 3, Herba Ephedrae 10, Ramulus Cinnamomi 10, Cornu Cervi Degelatinatum 15, gun additioner 30.
3, Chinese patent medicine as claimed in claim 1 is characterized in that wherein the weight proportion of each raw material is: Radix Ilicis Pubescentis 60, Radix Angelicae Sinensis 15, the Radix Rehmanniae 20, Rhizoma Chuanxiong 10, Radix Paeoniae Rubra 18, Radix Salviae Miltiorrhizae 25, Flos Carthami 15, Semen Persicae 10, Herba Asari 3, Olibanum (processed) 10, Myrrha (processed) 10, Caulis Spatholobi 30, Hirudo 10, Scolopendra 10, Pheretima 12, Scorpio 3, Squama Manis 3, Agkistrodon 3, the Radix Astragali 30, Radix Codonopsis 15.
4, Chinese patent medicine as claimed in claim 1 is characterized in that wherein the weight proportion of each raw material is: Radix Ilicis Pubescentis 60, Radix Angelicae Sinensis 15, the Radix Rehmanniae 20, Rhizoma Chuanxiong 10, Radix Paeoniae Rubra 18, Radix Salviae Miltiorrhizae 25, Flos Carthami 15, Semen Persicae 10, Herba Asari 3, Olibanum (processed) 10, Myrrha (processed) 10, Caulis Spatholobi 30, Hirudo 10, Scolopendra 10, Pheretima 12, Scorpio 3, Squama Manis 3, Agkistrodon 3, Flos Lonicerae 90, Radix Scrophulariae 60, Herba Violae 30, Radix Glycyrrhizae 15.
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