CN107412681A - A kind of medicine for treating Buerger's disease and preparation method thereof - Google Patents

A kind of medicine for treating Buerger's disease and preparation method thereof Download PDF

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CN107412681A
CN107412681A CN201710758191.1A CN201710758191A CN107412681A CN 107412681 A CN107412681 A CN 107412681A CN 201710758191 A CN201710758191 A CN 201710758191A CN 107412681 A CN107412681 A CN 107412681A
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impurity
picked
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王文春
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    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/58—Reptiles
    • A61K35/583—Snakes; Lizards, e.g. chameleons
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    • A61K35/586—Turtles; Tortoises, e.g. terrapins
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    • A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
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Abstract

The invention discloses a kind of medicine for treating Buerger's disease and preparation method thereof, its be mainly safflower, styrax, storax, monkshood, Chinese cassia tree, the wind-weed, earthworm, Rhizoma Sparganii, curcuma zedoary, the red sage root, frankincense, myrrh, play both sides of the street, blood rattan, dragonhead, fern asparagus fern, the constant weight such as pseudo-ginseng proportioning are prepared, medicine of the present invention has promoting blood circulation and removing blood stasis, the function of Xiao Ji Zhi Tong, it is quick for treating Buerger's disease, good effect, do not recur.

Description

A kind of medicine for treating Buerger's disease and preparation method thereof
Technical field
The present invention relates to a kind of medicine for treating Buerger's disease and preparation method thereof, belongs to the field of Chinese medicines.
Background technology
Buerger's disease is to cause occlusion in arteriolar spasm and thrombosis, causes ischaemic.This disease Person between twenty and fifty are more common in, are apt to occur in lower limb.Suffering limb is presented that momentary or continuation is pale, cyanosis, has a scorching hot and shouting pain, and sick limb is sagging When color of the leather redden, bleach during upper act, followed by toes are numb, Calf muscle pain, excite during walking, disappear during rest；Calf Shallow phlebitis and oedema often occurs.At present, because Western medicine can not effectively treat Buerger's disease, and operative treatment It is costly, therefore great demand be present to the Chinese medicine of effectively treatment Buerger's disease in people.
The content of the invention
The present inventor has been successfully found effective treatment thrombus finally according to secret recipe handed down from one's ancestors and the checking repeatedly of clinical test The medicine of obliterans, so as to complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine composition of effectively treatment Buerger's disease.
Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.
Medicine of the present invention is selection safflower, styrax, storax, monkshood, Chinese cassia tree, the wind-weed, earthworm, Rhizoma Sparganii, curcuma zedoary, pellet Ginseng, frankincense, myrrh, play both sides of the street, blood rattan, dragonhead, fern asparagus fern, pseudo-ginseng, nepal pennywort herb, the tuber of dwarf lilyturf, shoulder plate return, red child Youngster, cymbopogon distans, Giantleaf Ardisia Rhizome, elatostema umbellatum, manystem stonecrop leaf, tortoise version, notopterygium root, levisticum, Trigonotis peduncularis, frangipanis, masson pine branchlet-tip, sweetgum are posted Life, giant knotweed, kelp, marine alga, scorpio, gecko, drymoglossum-like lepidogrammitis herb, fine stern wind are combined preparation, and these drug regimens are caused Each efficacy of drugs produces synergy, so as to effectively treat icteric hepatitis.It is wherein because its nature and flavor from safflower It is sweet, to put down, enter the heart, Liver Channel, have promoting blood circulation and removing blood stasis, dissipate the strongly fragrant function of opening knot, control troubled thoughts pent-up, chest diaphragm ruffian is vexed, spits blood, and typhoid fever goes mad, It is frightened to be afraid of in a trance, women's Amenorrhea, postpartum blood stasis stomachache, tumbling and swelling.From styrax be because its nature and flavor work hard, temperature, enter the heart, Liver, the spleen channel, have and have one's ideas straightened out, and ward off dirty, the function of qi and blood circulation promotion, control palsy and faint cruelly, trusted subordinate's pain, postpartum anemic fainting, little Jing Epilepsy, wandering arthritis waist Bitterly.It is because its nature and flavor is pungent from storax, temperature, enters lung, Liver Channel, have sensible, ward off dirty, open strongly fragrant, the function of slit phlegm, controls soldier's right dusk , phlegm stops up , Jing Epilepsy of losing consciousness, a kind of malaria, the sudden pain of trusted subordinate, mange, pernio.It is because its property acrid-sweet flavor from monkshood, heat is poisonous, enters The heart, spleen, kidney channel, there is back sun to mend fire, the function of dispelling cold and removing dampness, control yin excess network sun, loss of YANG due to profuse perspiration, tell profit and faint inverse, trusted subordinate's crymodynia, spleen Cold dysentery is let out, tinea pedis oedema, infantile chronic fright, wind-cold-dampness arthralgia, Wei lame contractions, cloudy subcutaneous ulcer sore is leaked and the disease of all chronic diseaseses.From meat Osmanthus is because its property acrid-sweet flavor, heat, enters kidney, spleen, bladder warp, has complement positive, warming spleen and stomach, removing internal cold, the function of promoting blood circulation, controls life Door fire declines, cold weak pulse of limb, yang depletion collapse, diarrhea of suffering from abdominal pain, cold hernia run quickly globefish, waist and knee crymodynia, Jing Bi Disorder lumps in the abdomen, cloudy subcutaneous ulcer, streamer, and empty sun It is floating to get over, heat in the upper and cold in the lower.It is because its is bitter in taste from the wind-weed, trembles with fear, enter lung, stomach, kidney channel, there is nourishing Yin and falling fire, the work(of moisturize laxation Can, control dysphoria with smothery sensation and quench one's thirst, hectic fever due to yin labor heat, cough with lung heat, dry feces, difficult urination.It is because its nature and flavor is salty from earthworm, trembles with fear, Enter liver, spleen, lung channel, there is a heat-clearing, soothing the liver, Zhichuan, the function of dredging collateral, and it is manic to control high fever, convulsion, headache due to pathogenic wind-heat, hot eyes, in Wind hemiplegia, pants, larynx numbness, arthralgia, bleeding from the gum, urinary obstruction, scrofula, mumps, sore.It is from Rhizoma Sparganii because its property It is bitterly, to put down, enter liver, the spleen channel have a blood-breaking, promoting the circulation of qi, disperse accumulations, the function , Zhi lumps in the chest and abdomen of analgesic, and qi and blood coagulates band, trusted subordinate's pain, Swollen pain under the side of body, Amenorrhea, postpartum blood stasis stomachache, traumatic injury, sore swells are hard.It is from curcuma zedoary because its nature and flavor acrid, bitter, warm.Return Liver, the spleen channel.Promoting the circulation of qi blood-breaking, Xiao Ji Zhi Tong.Yong Yu abdominal lump of mass in abdomen, blood stasis closed, dyspepsia distending pain, treating swelling and pain by traumatic injury, early cervical carcinoma. It is because its bitter in taste, tepor from the red sage root, enters the heart, Liver Channel, have blood circulation and promoting silt, calming heart and tranquilizing mind, apocenosis, the function of analgesic, control Angina pectoris, irregular menstruation, dysmenorrhoea, to close, metrorrhagia band Xia , Disorder lumps in the abdomen, accumulation, abdominal pain due to blood stasis, arthralgia, shock palpitation not sleep, malignant sore Pyogenic infections.It is because its nature and flavor is worked hard from frankincense, temperature, enters the heart, liver, the spleen channel, have regulating qi and activating blood, analgesic therapy, the function of chasing after poison, control gas Blood stagnation, trusted subordinate's pain, ulcerative carbuncle pyogenic infections, traumatic injury, dysmenorrhoea, postpartum blood stasis stabbing pain.Be from myrrh because its is bitter in taste, It is flat, enter Liver Channel, there are scattered blood stasis eliminatings, the function of detumescence ding-tong, control and fall damage, metal-inflicted wound, muscles and bones, all pains of trusted subordinate, Disorder lumps in the abdomen, Amenorrhea, ulcer Swelling and pain, anal fistula, mesh barrier.It is because its is bitter in taste flat from playing both sides of the street, pass through 12 warps, there is dispelling wind and removing obstruction in the meridians, the work(of promoting urination and removing dampness Can, harness the river swollen, turgor, Amenorrhea, breast is few, brothers' contraction.It is because its nature and flavor octanoic acid, temperature, there is blood-nourishing dispersing blood stasis, qi-regulating from blood rattan The function of dampness elimination, control consumptive disease and hinder bleeding, podomere ache, heart and stomach pain, tinea pedis Impotence numbness, irregular menstruation, traumatic injury.It is blue or green from full leaf Orchid is because its is bitter in taste, temperature, has and relievings asthma, antibechic, the function of anti-inflammatory, punish-old year chronic bronchitis.From fern asparagus fern be because It is sweet, light, flat for its nature and flavor, enter lung channel, moisten the lung and relieve the cough, the antipruritic function of desinsection controls pulmonary tuberculosis chronic cough, lung abscess, pertussis, Cough up sputum streaked with blood, bronchial astehma.It is because its property sweet and slightly bitter taste from pseudo-ginseng, temperature, enter liver, stomach, large intestine channel, there is hemostasis, dissipate the stasis of blood, Detumescence, the function of analgesic therapy, control haematemesis, hemoptysis, bleeding from five sense organs or subcutaneous tissue, have blood in stool, bloody flux, uterine bleeding , Disorder lumps in the abdomen, postpartum anemic fainting, lochia not under, fall and flutter the stasis of blood Blood, traumatism and bleeding, carbuncle swells pain.）From nepal pennywort herb be because its cool in nature, mildly bitter flavor, it is nontoxic, control traumatic injury, catch a cold, cough Cough phlegm blood.It is because its property sweet and slightly bitter taste from the tuber of dwarf lilyturf, trembles with fear, enter lung, stomach, the heart channel of Hang-Shaoyin, there is Yin nourishing and lung moistening, relieving restlessness that clears away heart-fire, beneficial stomach The function of promoting the production of body fluid, dryness of the lung dry cough is controlled, spitted blood, spitting of blood, consumptive lung disease, lung carbuncle, consumptive disease dysphoria with smothery sensation is clear thirsty, pyreticosis Tianjin wound, dry throat, just It is secret.It is because its nature and flavor is bitter from shouldering plate to return, puts down, favourable water, heat-clearing, promoting blood circulation, the function of removing toxic substances, harness the river swollen, jaundice, let out Rush down, malaria, dysentery, pertussis, stranguria with turbid discharge, erysipelas, scrofula, eczema, mange.It is because its nature and flavor is sweet from the red kid, trembles with fear, control sense Emit cough, treating rheumatic ostealgia, pain in the back, indigestion, treating swelling and pain by traumatic injury, furunculosis.From cymbopogon distans worked hard because of its nature and flavor, it is cool, have Inducing diaphoresis, dampness removing, relieving asthma, the function of cough-relieving, the heat that cures the wound is caught a cold, and gonorrhoea, rheumatism muscles and bones is ached, chronic bronchitis.From Giantleaf Ardisia Rhizome It is because its nature and flavor is pungent, temperature, has wind-damp dispelling, strengthen the bone, the function of promoting blood circulation, control rheumatism arthralgia and myalgia, traumatic injury, postpartum Blood stasis, ulcer ulcer.From elatostema umbellatum be because its mild-natured, mildly bitter flavor, it is nontoxic, control dysentery, rheumatalgia, jaundice, oedema, nothing Name pyogenic infections, fracture.It is the sweet micro-pungent because its cold nature from manystem stonecrop leaf, has clearing heat and detoxicating, hemostasis, the function of wind-damp dispelling, controls Abscess of throat, nosebleed epistaxis, wind-heat is dizzy, rheumatic arthritis, nasal eczema, eczema, sore.It is because its nature and flavor is salty sweet from tortoise version, puts down, Enter liver and kidney channel, have enriching yin, checking exuberance of yang, kidney tonifying, the function of strong bone, control the deficiency of the kidney yin, hectic fever due to yin labor heat, spit blood, bleeding from five sense organs or subcutaneous tissue, chronic cough, lose Essence, uterine bleeding, with, pain in the back, the atrophic debility of bones, wind formation from yin deficiency, protracted dysentery, chronic malaria, hemorrhoid, non-closure of fontanels jin infants.It is because of it from notopterygium root Nature and flavor are worked hard, and temperature, enter bladder, kidney channel, there is scattered exterior cold, and wind-damp dispelling, the function in sharp joint, cure cold chill, lossless, chill of having a headache Arthritis with fixed pain caused by dampness, item strengthening tendons is anxious, joint ache, geomantic omen edema, skin sore.It is because its nature and flavor is worked hard from levisticum, temperature, enters kidney, wing Guang passes through, and has wind-dispelling, wins wet, cold dispelling, the function of analgesic, controls wind-cold-dampness arthralgia, waist urushic acid pain, trick contraction pain, chronic bronchitis, head Bitterly, dentalgia.From Trigonotis peduncularis worked hard because of its nature and flavor, it is cool, the enuresis is controlled, dysentery, carbuncle on the back, heat is swollen, numbness in hands and feet.From chicken Egg flower is because its nature and flavor is sweet, is put down, nontoxic, controls damp-heat diarrhea, tenesmus, and can moistening lung removing toxic substances.Be from masson pine branchlet-tip because Its is warm-natured, bitter and puckery flavor, there is the function of promoting blood circulation and stopping pain, controls traumatic injury, urine leaching pain.It is because its nature and flavor is pungent from flatshoot mistletoe branchlet and leaf Hardship, temperature, there is wind-dispelling, invigorates blood circulation, and dehumidifying, cough-relieving, the function of eliminating the phlegm, controls waist and aches, treating rheumatic ostealgia, epersalgia cough, dysentery, Under uterine bleeding band, puerperal abdominalgia with blood stasis, sore scabies.It is because its is bitter in taste from giant knotweed, puts down, there is wind-dispelling, dampness removing, broken stasis of blood, the work(to stimulate the menstrual flow Can, control rheumatism arthralgia and myalgia, jaundice with damp-heat pathogen, under stranguria with turbid discharge band, women's Amenorrhea, lochiostasis , lumps in the chest and abdomen, blood under anal fistula, Injury from falling down, scald, malignant sore tinea.It is because its nature and flavor is salty from kelp, trembles with fear, enter stomach, there are softening hard masses, the function of water-filling, control Scrofula, goiter and tumor is dysphagic, oedema, testiclar gall, under band.It is because its is bitter in taste salty from marine alga, trembles with fear, enter lung, spleen, kidney channel, have Softening hard masses, dissolving phlegm, Li Shui, the function of expelling the heat-evil, control scrofula, goiter and tumor, accumulation, oedema, tinea pedis, testiclar gall.Be from scorpio because Its nature and flavor is salty pungent, puts down, poisonous, has wind-dispelling, only convulsion, and dredging collateral, the function of removing toxic substances controls convulsion , Dian Epilepsy, apoplexy, hemiplegia, Kou Yan crooked are oblique, antimigraine, arthralgia pain due to rheumatism, lockjaw, scrofula, rubella sore swells.From gecko be because its nature and flavor it is salty, It is cold, it is slightly poisonous, there is wind-dispelling, calm the frightened, dissipating bind, the function of removing toxic substances, control paralysis due to windstroke, severe and wadering arthralgia pain, wind phlegm Jing Epilepsy, scrofula, malignant sore. Be from drymoglossum-like lepidogrammitis herb because its is bitter in taste, it is cool, have clearing heat and detoxicating, the function of dampness removing dispersing blood stasis, control mumps, abscess of throat, gall-bladder Inflammation, lump in the abdomen, tympanites, consumptive disease hemoptysis, scrofula, stranguria with turbid discharge hematuria, malignant boil ulcerative carbuncle swell, traumatic injury.It is from fine stern wind because its nature and flavor Pungent, temperature has expelling wind and clearing away cold, and the function for sterilization of invigorating blood circulation controls treating rheumatic ostealgia, cough due to wind-cold evil, coldaccumulating abdominalgia, nameless sores or boils, and bruise is stung Wound.
Embodiment
The drug dose of instant component is also that inventor show that the dosage of each component is following heavy by largely groping to summarize All there is the effect of preferable in the range of amount：
5-9 grams of safflower, 5-8 grams of styrax, 5-8 grams of storax, 5-8 grams of monkshood, 6-9 grams of Chinese cassia tree, 12-18 grams of the wind-weed, earthworm 12-15 grams, 9-15 grams of Rhizoma Sparganii, 9-15 grams of curcuma zedoary, 25-30 grams of the red sage root, 12-15 grams of frankincense, 12-15 grams of myrrh, play both sides of the street 25-30 Gram, 25-30 grams of blood rattan, 9-15 grams of dragonhead, 9-15 grams of fern asparagus fern, 3-8 grams of pseudo-ginseng, 20-30 grams of nepal pennywort herb, the tuber of dwarf lilyturf 9-15 grams, shoulder plate return 20-30 grams, 9-15 grams of the red kid, 20-30 grams of cymbopogon distans, 20-30 grams of Giantleaf Ardisia Rhizome, 9-15 grams of elatostema umbellatum, 9-15 grams of manystem stonecrop leaf, 25-30 grams of tortoise version, 12-15 grams of notopterygium root, 12-15 grams of levisticum, 9-15 grams of Trigonotis peduncularis, 8-12 grams of frangipanis, pine Written 60-70 grams, 12-15 grams of flatshoot mistletoe branchlet and leaf, 20-30 grams of giant knotweed, 12-15 grams of kelp, 12-15 grams of marine alga, 5-8 grams of scorpio, wall Brave 6-9 grams, 20-30 grams of drymoglossum-like lepidogrammitis herb, 30-40 grams of fine stern wind.
Preferably
6 grams of safflower, 6 grams of styrax, 6 grams of storax, 6 grams of monkshood, 8 grams of Chinese cassia tree, 15 grams of the wind-weed, 15 grams of earthworm, 15 grams of Rhizoma Sparganii, 15 grams of curcuma zedoary, 30 grams of the red sage root, 15 grams of frankincense, 15 grams of myrrh, play both sides of the street 30 grams, 30 grams of blood rattan, 12 grams of dragonhead, fern asparagus fern 12 grams, 6 grams of pseudo-ginseng, 25 grams of nepal pennywort herb, 12 grams of the tuber of dwarf lilyturf, shoulder plate return 25 grams, 12 grams of the red kid, 25 grams of cymbopogon distans, Giantleaf Ardisia Rhizome 25 grams, 12 grams of elatostema umbellatum, 12 grams of manystem stonecrop leaf, 30 grams of tortoise version, 15 grams of notopterygium root, 15 grams of levisticum, 12 grams of Trigonotis peduncularis, 9 grams of frangipanis, 65 grams of masson pine branchlet-tip, 15 grams of flatshoot mistletoe branchlet and leaf, 25 grams of giant knotweed, 15 grams of kelp, 15 grams of marine alga, 6 grams of scorpio, 8 grams of gecko, drymoglossum-like lepidogrammitis herb 25 Gram, 35 grams of fine stern wind.
The preparation method of medicine of the present invention is as follows
First, stock up
1st, safflower：Impurity is picked, and removes yellow feeler；
2nd, styrax：Crude drug is taken, impurity is removed, breaks into fritter；
3rd, storax：Bark is wounded or cut by early summer, as deep as woody part, is made secretion face cream, is infiltrated skin zone, tree is peeled to autumn Skin, face cream is squeezed, residue squeezes again after adding boiling, removes the early-products of impurity, as storax；Such a early-products are dissolved in again In alcohol, filtering, alcohol is boiled off, then into styrax depuratus；
4th, monkshood：It is soaked in water, pulls out, cuts into slices, dry；
5th, Chinese cassia tree：Net impurity is picked, scrapes off tertia, the used time smashes, or scrapes off tertia, infiltrates a moment with warm water, section, dries；
6th, the wind-weed：Net impurity is picked, is hit and washed with water, is pulled out, is softened, section is dried；
7th, earthworm：Impurity is picked, is rinsed with water, is pulled out in time, is dried, segment；
8th, Rhizoma Sparganii：Net impurity is picked, is soaked in water, pulls out and runs through, cuts into slices, dries；
9th, curcuma zedoary：Crude drug is taken, impurity is removed, size stepping, cleans, slightly soak, take out, run through, shave, dry, weed out Chip；
10th, the red sage root：Net impurity is picked, removes rhizome, is cleaned, is pulled out, cut into slices, dry after running through；
11st, frankincense：Pick sand impurity；
12nd, myrrh：Impurity is picked, breaks into fragment；
13rd, play both sides of the street：Impurity is removed, cleans, dries；
14th, blood rattan：Water logging is run through, and section, is dried；
15th, dragonhead：Summer harvests, and removes silt, dead leaf, dries；
16th, fern asparagus fern：Spring, the excavation of season in autumn two, remove stem, clean, decortication, dry；
17th, pseudo-ginseng：Net impurity is picked, is smashed to pieces, cuts into slices and dries after grinding or running through；
18th, nepal pennywort herb：Whole year can adopt, and dry；
19th, the tuber of dwarf lilyturf：Net impurity is picked, is soaked in water, is pulled out, the heart is pumped after running through, then clean and dry；
20th, plate is shouldered to return：Autumn harvests, and cleans, dries；
21st, the red kid：Whole year can adopt, and clean, dry；
22nd, cymbopogon distans：Aerial part is extracted at the beginning of autumn late summer, is dried；
23rd, Giantleaf Ardisia Rhizome：Autumn excavates, and cleans, and removes fibrous root, dries；
24th, elatostema umbellatum：Spring, summer take, and clean, dry；
25th, manystem stonecrop leaf：Summer, autumn collection, are dried；
26th, tortoise version：Soaked with clear water, scrape off residual meat, cleaned, dry, knock fritter；
27th, notopterygium root：Impurity is picked, cleans, runs through, cuts into slices, dries；
28th, levisticum：Impurity is picked, separates size, cleans, is cut into slices after running through, is dried；
29th, Trigonotis peduncularis：Early summer harvests, and dries；
30th, frangipanis：Summer, autumn harvesting blooming flower piece, are dried；
31st, masson pine branchlet-tip：Net impurity is picked, is dried；
32nd, flatshoot mistletoe branchlet and leaf：Summer, autumn harvesting, are dried；
33rd, giant knotweed：Crude drug is taken, impurity is removed, cleaning, drying, splits broken；
34th, kelp：Impurity is picked, is rinsed with water, wide silk is cut into, dries；
35th, marine alga：Impurity is picked, is slightly floated with water, is slightly dried in the air, segment, dry；
36th, scorpio：Clear water floats the matter that desalts, and dries, or low baking temperature roasting is used；
37th, gecko：Crude drug is taken, removes impurity；
38th, the seed of cowherb：Winnow with a dustpan net impurity, put in pot
39th, drymoglossum-like lepidogrammitis herb：Net impurity is picked, is dried；
40th, fine stern wind：Whole year can adopt, and dry.
2nd, prepare
1st, take monkshood to add 2 grams of salt, 3 grams of water to mix rear fried dry thoroughly, grind；
2nd, Rhizoma Sparganii, curcuma zedoary, frankincense, myrrh, tortoise version is taken with 2 grams of mature vinegar fried drys, to grind respectively；
3rd, take safflower, styrax, storax, Chinese cassia tree, the wind-weed, earthworm, the red sage root, play both sides of the street, blood rattan, dragonhead, fern day Winter, pseudo-ginseng, nepal pennywort herb, the tuber of dwarf lilyturf, shoulder plate return, the red kid, cymbopogon distans, Giantleaf Ardisia Rhizome, elatostema umbellatum, manystem stonecrop leaf, notopterygium root, solely Work, Trigonotis peduncularis, frangipanis, masson pine branchlet-tip, flatshoot mistletoe branchlet and leaf, giant knotweed, kelp, marine alga, scorpio, gecko, drymoglossum-like lepidogrammitis herb, fine stern windmill into Broken medicinal powder；
4th, take 400 grams of heating of refined honey to boil 5 minutes, add the above-mentioned medicinal powder all ground, stir, be cooked by slow fire 12 minutes, Temperature is treated, the particle pill of sorghum rice size is made, shady place is put and dries in the shade and produce.
Safflower is promoting blood circulation and removing blood stasis in prescription, and the scattered stasis of blood opens knot, and styrax, which has, has one's ideas straightened out, and the function of qi and blood circulation promotion, storax has sensible It is monarch drug in a prescription to open strongly fragrant function；Chinese cassia tree has the function and monkshood, the wind-weed, earthworm, Rhizoma Sparganii, curcuma zedoary, the red sage root, frankincense, myrrh of promoting blood circulation For ministerial drug；12 taste medicines play promoting blood circulation and removing blood stasis jointly, dissipate Yu Kaijie, the effect of nourishing Yin and falling fire can effect a permanent cure.Play both sides of the street have dispelling wind and removing obstruction in the meridians, The function of promoting urination and removing dampness and blood rattan, dragonhead, fern asparagus fern, pseudo-ginseng, nepal pennywort herb, the tuber of dwarf lilyturf, shoulder plate return, the red kid, rue Vanilla is adjutant；Giantleaf Ardisia Rhizome has the function of promoting blood circulation, is medicine is taken stopgap measures with all medicines that is left.
Medicine of the present invention has promoting blood circulation and removing blood stasis, the function of Xiao Ji Zhi Tong, for treat Buerger's disease it is quick, Good effect, do not recur.
The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these experiments include medicine of the present invention Animal toxicity test and clinical observation on the therapeutic effect experiment.
The animal toxicity test of [test example 1] medicine of the present invention
West Germany rabbit 30 is taken, male and female dual-purpose, body weight 2.0-2.5kg, is divided into two groups, one of which is overdose, and another group is just Constant, pill overdose group 0.35g/kg, normal amount group 0.15g/kg are taken, using dilution administration by gavage administration, twice a day, connected It is continuous to take 7 days, observation administration reaction, the results showed that rabbit activity, diet are normal, and medicine is without bad toxic side effect.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1st, general information
Accept out-patient totally 37 for medical treatment.
2nd, diagnostic criteria
Suffering limb is presented that momentary or continuation is pale, cyanosis, has a scorching hot and shouting pain, and color of the leather reddens when sick limb is sagging, upper act time-varying In vain, followed by toes are numb, Calf muscle pain, excite during walking, disappear during rest；Calf often occur shallow phlebitis and Oedema.It was found that pulsation of foot dorsal artery weakens or disappeared.
3rd, treatment method
Above-mentioned particle pill is taken to patient, 8 grams every time, it is early, middle and late daily it is each once, 30 days as one therapeutic course, even served 4 The course for the treatment of.
4th, efficacy assessment standard
It is effective：Buerger's disease symptom disappears, recovery from illness；
Take a turn for the better：Limb pain mitigates, edema extinction, and feeling of numbness disappears, and progressively recovers normal；
It is invalid：Improvement standard person is not reached.
5th, treatment results（It see the table below）：
In above-mentioned treatment, with drug therapy Patients With Thromboangitis Obliterans 37 of the present invention, as a result effective 29, obvious effective rate For 78.38%, take a turn for the better 6, improvement rate 16.22%, invalid 2, total effective rate 94.60%.

Claims (3)

  1. A kind of 1. medicine for treating Buerger's disease, it is characterised in that：It is by the bulk drug in following weight range It is made：
    5-9 grams of safflower, 5-8 grams of styrax, 5-8 grams of storax, 5-8 grams of monkshood, 6-9 grams of Chinese cassia tree, 12-18 grams of the wind-weed, earthworm 12-15 grams, 9-15 grams of Rhizoma Sparganii, 9-15 grams of curcuma zedoary, 25-30 grams of the red sage root, 12-15 grams of frankincense, 12-15 grams of myrrh, play both sides of the street 25-30 Gram, 25-30 grams of blood rattan, 9-15 grams of dragonhead, 9-15 grams of fern asparagus fern, 3-8 grams of pseudo-ginseng, 20-30 grams of nepal pennywort herb, the tuber of dwarf lilyturf 9-15 grams, shoulder plate return 20-30 grams, 9-15 grams of the red kid, 20-30 grams of cymbopogon distans, 20-30 grams of Giantleaf Ardisia Rhizome, 9-15 grams of elatostema umbellatum, 9-15 grams of manystem stonecrop leaf, 25-30 grams of tortoise version, 12-15 grams of notopterygium root, 12-15 grams of levisticum, 9-15 grams of Trigonotis peduncularis, 8-12 grams of frangipanis, pine Written 60-70 grams, 12-15 grams of flatshoot mistletoe branchlet and leaf, 20-30 grams of giant knotweed, 12-15 grams of kelp, 12-15 grams of marine alga, 5-8 grams of scorpio, wall Brave 6-9 grams, 20-30 grams of drymoglossum-like lepidogrammitis herb, 30-40 grams of fine stern wind.
  2. 2. medicine according to claim 1, wherein the dosage of each bulk drug is：
    6 grams of safflower, 6 grams of styrax, 6 grams of storax, 6 grams of monkshood, 8 grams of Chinese cassia tree, 15 grams of the wind-weed, 15 grams of earthworm, 15 grams of Rhizoma Sparganii, 15 grams of curcuma zedoary, 30 grams of the red sage root, 15 grams of frankincense, 15 grams of myrrh, play both sides of the street 30 grams, 30 grams of blood rattan, 12 grams of dragonhead, fern asparagus fern 12 grams, 6 grams of pseudo-ginseng, 25 grams of nepal pennywort herb, 12 grams of the tuber of dwarf lilyturf, shoulder plate return 25 grams, 12 grams of the red kid, 25 grams of cymbopogon distans, Giantleaf Ardisia Rhizome 25 grams, 12 grams of elatostema umbellatum, 12 grams of manystem stonecrop leaf, 30 grams of tortoise version, 15 grams of notopterygium root, 15 grams of levisticum, 12 grams of Trigonotis peduncularis, 9 grams of frangipanis, 65 grams of masson pine branchlet-tip, 15 grams of flatshoot mistletoe branchlet and leaf, 25 grams of giant knotweed, 15 grams of kelp, 15 grams of marine alga, 6 grams of scorpio, 8 grams of gecko, drymoglossum-like lepidogrammitis herb 25 Gram, 35 grams of fine stern wind.
  3. 3. the preparation method of medicine according to claim 1 or claim 2, it is characterised in that：It comprises the following steps：
    （One）Stock
    （1）Safflower：Impurity is picked, and removes yellow feeler；
    （2）Styrax：Crude drug is taken, impurity is removed, breaks into fritter；
    （3）Storax：Bark is wounded or cut by early summer, as deep as woody part, is made secretion face cream, is infiltrated skin zone, tree is peeled to autumn Skin, face cream is squeezed, residue squeezes again after adding boiling, removes the early-products of impurity, as storax；Such a early-products are dissolved in again In alcohol, filtering, alcohol is boiled off, then into styrax depuratus；
    （4）Monkshood：It is soaked in water, pulls out, cuts into slices, dry；
    （5）Chinese cassia tree：Net impurity is picked, scrapes off tertia, the used time smashes, or scrapes off tertia, infiltrates a moment with warm water, section, dries；
    （6）The wind-weed：Net impurity is picked, is hit and washed with water, is pulled out, is softened, section is dried；
    （7）Earthworm：Impurity is picked, is rinsed with water, is pulled out in time, is dried, segment；
    （8）Rhizoma Sparganii：Net impurity is picked, is soaked in water, pulls out and runs through, cuts into slices, dries；
    （9）Curcuma zedoary：Crude drug is taken, impurity is removed, size stepping, cleans, slightly soak, take out, run through, shave, dry, weed out Chip；
    （10）The red sage root：Net impurity is picked, removes rhizome, is cleaned, is pulled out, cut into slices, dry after running through；
    （11）Frankincense：Pick sand impurity；
    （12）Myrrh：Impurity is picked, breaks into fragment；
    （13）Play both sides of the street：Impurity is removed, cleans, dries；
    （14）Blood rattan：Water logging is run through, and section, is dried；
    （15）Dragonhead：Summer harvests, and removes silt, dead leaf, dries；
    （16）Fern asparagus fern：Spring, the excavation of season in autumn two, remove stem, clean, decortication, dry；
    （17）Pseudo-ginseng：Net impurity is picked, is smashed to pieces, cuts into slices and dries after grinding or running through；
    （18）Nepal pennywort herb：Whole year can adopt, and dry；
    （19）The tuber of dwarf lilyturf：Net impurity is picked, is soaked in water, is pulled out, the heart is pumped after running through, then clean and dry；
    （20）Plate is shouldered to return：Autumn harvests, and cleans, dries；
    （21）The red kid：Whole year can adopt, and clean, dry；
    （22）Cymbopogon distans：Aerial part is extracted at the beginning of autumn late summer, is dried；
    （23）Giantleaf Ardisia Rhizome：Autumn excavates, and cleans, and removes fibrous root, dries；
    （24）Elatostema umbellatum：Spring, summer take, and clean, dry；
    （25）Manystem stonecrop leaf：Summer, autumn collection, are dried；
    （26）Tortoise version：Soaked with clear water, scrape off residual meat, cleaned, dry, knock fritter；
    （27）Notopterygium root：Impurity is picked, cleans, runs through, cuts into slices, dries；
    （28）Levisticum：Impurity is picked, separates size, cleans, is cut into slices after running through, is dried；
    （29）Trigonotis peduncularis：Early summer harvests, and dries；
    （30）Frangipanis：Summer, autumn harvesting blooming flower piece, are dried；
    （31）Masson pine branchlet-tip：Net impurity is picked, is dried；
    （32）Flatshoot mistletoe branchlet and leaf：Summer, autumn harvesting, are dried；
    （33）Giant knotweed：Crude drug is taken, impurity is removed, cleaning, drying, splits broken；
    （34）Kelp：Impurity is picked, is rinsed with water, wide silk is cut into, dries；
    （35）Marine alga：Impurity is picked, is slightly floated with water, is slightly dried in the air, segment, dry；
    （36）Scorpio：Clear water floats the matter that desalts, and dries, or low baking temperature roasting is used；
    （37）Gecko：Crude drug is taken, removes impurity；
    （38）The seed of cowherb：Winnow with a dustpan net impurity, put in pot
    （39）Drymoglossum-like lepidogrammitis herb：Net impurity is picked, is dried；
    （40）Fine stern wind：Whole year can adopt, and dry；
    （Two）Prepare
    （1）Take monkshood to add 2 grams of salt, 3 grams of water to mix rear fried dry thoroughly, grind；
    （2）Rhizoma Sparganii, curcuma zedoary, frankincense, myrrh, tortoise version is taken with 2 grams of mature vinegar fried drys, to grind respectively；
    （3）Take safflower, styrax, storax, Chinese cassia tree, the wind-weed, earthworm, the red sage root, play both sides of the street, blood rattan, dragonhead, fern day Winter, pseudo-ginseng, nepal pennywort herb, the tuber of dwarf lilyturf, shoulder plate return, the red kid, cymbopogon distans, Giantleaf Ardisia Rhizome, elatostema umbellatum, manystem stonecrop leaf, notopterygium root, solely Work, Trigonotis peduncularis, frangipanis, masson pine branchlet-tip, flatshoot mistletoe branchlet and leaf, giant knotweed, kelp, marine alga, scorpio, gecko, drymoglossum-like lepidogrammitis herb, fine stern windmill into Broken medicinal powder；
    （4）Take 400 grams of heating of refined honey to boil 5 minutes, add the above-mentioned medicinal powder all ground, stir, be cooked by slow fire 12 minutes, Temperature is treated, the particle pill of sorghum rice size is made, shady place is put and dries in the shade and produce.
CN201710758191.1A 2017-08-29 2017-08-29 A kind of medicine for treating Buerger's disease and preparation method thereof Pending CN107412681A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1115247A (en) * 1994-07-18 1996-01-24 马世发 Anti-cold symptoms fragrant powder
CN1679843A (en) * 2005-01-27 2005-10-12 朱腾月 Oral medicine for treating thromboangitis obliterans
CN101053632A (en) * 2006-04-13 2007-10-17 吴希文 Traditional Chinese medicine for treating thromboangitis obliterans

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1115247A (en) * 1994-07-18 1996-01-24 马世发 Anti-cold symptoms fragrant powder
CN1679843A (en) * 2005-01-27 2005-10-12 朱腾月 Oral medicine for treating thromboangitis obliterans
CN101053632A (en) * 2006-04-13 2007-10-17 吴希文 Traditional Chinese medicine for treating thromboangitis obliterans

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