CN107596280A - A kind of medicine for treating atherosclerosis and preparation method thereof - Google Patents

A kind of medicine for treating atherosclerosis and preparation method thereof Download PDF

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CN107596280A
CN107596280A CN201711087890.4A CN201711087890A CN107596280A CN 107596280 A CN107596280 A CN 107596280A CN 201711087890 A CN201711087890 A CN 201711087890A CN 107596280 A CN107596280 A CN 107596280A
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马敏
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Abstract

The invention discloses a kind of medicine for treating atherosclerosis and preparation method thereof, it is mainly by leech, ground bettle, gecko, borneol, giant knotweed, marine alga, kelp, red halloysite, celery, the capsule of weeping forsythia, almond, japanese plum root-bark, jatamans valeriana rhizome, fortune firethorn fruit, Long Zhu, skink, buchanan cryptolepis root, cayropteris incana, radix polygonati officinalis, Blumea balsamifera, cholla stem, tripe is drawn, smilax, Rubus parvifolius, cymbopogon distans, Chinese prickly ash, Rhizoma Sparganii, curcuma zedoary, sowthistle, Chinese munronia herb, runcinate knotweed herb is prepared according to a certain weight ratio, the present invention has broken stasis of blood blood, stimulate the menstrual flow, calming liver and clearing heat, nourishing YIN for benefiting the kidney, clearing heat and detoxicating function, it is quick for treating atherosclerosis, good effect.

Description

A kind of medicine for treating atherosclerosis and preparation method thereof
Technical field
The present invention relates to a kind of medicine for treating atherosclerosis and preparation method thereof, belongs to the field of Chinese medicines.
Technical background
Atherosclerosis is a kind of chronic, gradual arterial disease, the fats portion that is deposited in artery during morbidity or All blood flow is blocked.When otherwise smooth, solid endarterium is roughening, thickens, and by fat, fibrin(One kind is used In the protein of blood coagulation), calcium and cell debris be when blocking, atherosclerosis just occurs.The traditional Chinese medical science then thinks Atherosclerosis Change relevant with venation block, the turbid heap soil or fertilizer over and around the roots Sheng of phlegm, obstructed circulation of nutrient QI and de fensive QI, caused by liver and kidney deficiency.Because western medicine side effect is big, therefore people are to having There is great demand in the Chinese medicine of effect treatment atherosclerosis, up to now, it has not been found that having on the present invention Close report.
The content of the invention
The present inventor is on the basis of secret prescription handed down in the family from generation to generation, and the checking repeatedly Jing Guo clinical test, works out and effectively control finally again The medicine of atherosclerosis is treated, so as to complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine composition of more effectively treatment atherosclerosis.
Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.
Medicine of the present invention is selection leech, ground bettle, gecko, borneol, giant knotweed, marine alga, kelp, red halloysite, celery, is connected Stick up, almond, japanese plum root-bark, jatamans valeriana rhizome, fortune firethorn fruit, Long Zhu, skink, buchanan cryptolepis root, cayropteris incana, radix polygonati officinalis, Blumea balsamifera, cholla stem, tripe Drawing, smilax, Rubus parvifolius, cymbopogon distans, Chinese prickly ash, Rhizoma Sparganii, curcuma zedoary, sowthistle, Chinese munronia herb, runcinate knotweed herb, turnip seed, crotalaria seesiliflora, Carambola, berba aristolochiae mollissimae, Rhizoma Panacis japonici are combined preparation, cause each efficacy of drugs to produce synergy these drug regimens, So as to effectively treat atherosclerosis.It is wherein because the salty hardship of its nature and flavor from leech, puts down, poisonous, enter liver, bladder Through, there is blood-breaking, by the stasis of blood, the function of stimulating the menstrual flow, control and store Xue , Disorder lumps in the abdomen, accumulation, women's Amenorrhea, dry blood is into consumptive disease, injury from falling down, conjunctival congestion with ophthalmalgia, Cloudiness.It is slightly poisonous, the return liver warp because its nature and flavor is salty, cold from ground bettle, has broken stasis of blood blood, the function of continuous muscles and bones, control muscles and bones folding Wound, blood stasis closed , abdominal lump of mass in abdomen.It is because its nature and flavor is salty from gecko, trembles with fear, it is slightly poisonous, there is wind-dispelling, calm the frightened, dissipating bind, removing toxic substances Function, control paralysis due to windstroke, severe and wadering arthralgia pain, wind phlegm Jing Epilepsy, scrofula, malignant sore.From borneol be because its nature and flavor work hard, it is cool, enter the heart, Lung channel, there are logical all keys, dissipate stagnated fire, go screen improving eyesight, the function of swelling and pain relieving, control apoplexy lockjaw, pyreticosis coma , Jing Epilepsy phlegm fans, gas Close deafness, larynx numbness, aphtha, tympanitis, carbuncle swells, hemorrhoid, conjunctivitis, enterobiasis.It is because its is bitter in taste from giant knotweed, puts down, There is a wind-dispelling, dampness removing, broken stasis of blood, the function of stimulating the menstrual flow controls rheumatism arthralgia and myalgia, jaundice with damp-heat pathogen, and under stranguria with turbid discharge band, women's Amenorrhea, postpartum dislikes Do not reveal , lumps in the chest and abdomen, blood under anal fistula, injury from falling down, scald, malignant sore tinea.It is because its is bitter in taste salty from marine alga, trembles with fear, Enter lung, spleen, kidney channel, there are softening hard masses, dissolving phlegm, Li Shui, the function of expelling the heat-evil, control scrofula, goiter and tumor, accumulation, oedema, tinea pedis, testiclar gall. It is because its nature and flavor is salty from kelp, trembles with fear, enter stomach, there are softening hard masses, the function of water-filling, control scrofula, goiter and tumor is dysphagic, oedema, testis Swelling and pain, with.Be the temperature because its property sweet-puckery flavor from red halloysite, enter spleen, stomach, large intestine channel, puckery intestines, hemostasis, hygroscopic, myogenic it Effect, chronic diarrhea is controlled, protracted dysentery, is had blood in stool, prolapse of the anus, seminal emission, uterine bleeding, with, unhealing ulcer.From celery be because its nature and flavor sweetness and bitterness, It is cool, enter the positive bright, JUE YIN meridian of foot, have calming liver and clearing heat, the function of expelling wind and removing dampness, control high blood pressure, dizziness and headache, flush red, blood Leaching, carbuncle swells.Be from the capsule of weeping forsythia because its is bitter in taste, it is cool, enter the heart, liver, gallbladder channel, there is heat-clearing, detoxify, dissipating bind, the function of detumescence, control Warm, erysipelas, macula, large carbuncle pyogenic infections, scrofula, urine leaching closes.It is because its is bitter in taste from almond, temperature is poisonous, enters lung, big Intestines pass through, and have expelling phlegm and arresting coughing, relieving asthma, the function of ease constipation, control exogenous cough, asthma is full, larynx numbness, dry constipation of intestines.From japanese plum root-bark be because It is bitter in taste for its, it is salty, tremble with fear, nontoxic, enter liver, spleen the heart channel of Hang-Shaoyin, have and drop inverse, eliminating dampness, clearing heat and detoxicating function, control circulation of vital energy in the wrong direction run quickly globefish, it is damp and hot Dysentery, leukorrhea with reddish discharge, quench one's thirst, tinea pedis, erysipelas sore carbuncle.It is because its nature and flavor is pungent from jatamans valeriana rhizome, temperature is nontoxic, enters lung, stomach two Through having in row, cold dispelling, promoting blood circulation, the function of menstruation regulating, controlling having a heatstroke abdominal distention, vomiting and diarrhea, lung qi oedema, anemofrigid cold, menstruation It is uncomfortable, consumptive disease wound cough.It is because its nature and flavor sweet acid from fortune firethorn fruit, has invigorating the spleen disperse accumulations, the function of promoting blood circulation and hemostasis, control lump in the abdomen, product Food, diarrhea, dysentery, uterine bleeding, postpartum blood stasis.It is because its is bitter in taste from imperial pearl, trembles with fear, it is nontoxic, control gonorrhoea, furunculosis.From stone Imperial son is because its nature and flavor is salty, is trembled with fear, poisonous, has broken knot, the function of water-filling, controls difficult urination, urolithiasis, malignant sore scrofula, ulcer on the shank.Choosing It is because its nature and flavor is light with buchanan cryptolepis root, puts down, it is poisonous, there is promoting blood circulation, subside a swelling, analgesic function, control bruise wound, fracture, Low Back Pain stomachache, Oedema.It is because its nature and flavor is pungent from cayropteris incana, temperature is nontoxic, has dispelling wind and eliminating dampness, the function of the cough relieving powder stasis of blood, cure cold heating, wind Wet ostalgia, pertussis, chronic bronchitis, irregular menstruation, uterine bleeding, leukorrhea, postpartum blood stasis are had a pain, traumatic injury, and pruitus is wet Rash, sore swells.It is because its nature and flavor is sweet from radix polygonati officinalis, puts down, enter lung, stomach, there is yin-nourishing, moisturize, relieving restlessness, the function of quenching the thirst, control heat Sick sun wound, cough, polydipsia, deficient fever, the paddy that disappears is easily hungry, frequent urination.It is because its nature and flavor is worked hard from Blumea balsamifera, temperature, has Middle benefit gas is invigorated blood circulation, dispelling wind and eliminating dampness, the function of desinsection, controls cold-dampness rush down dysentery, borborygmus of suffering from abdominal pain, swelling, arthralgia and myalgia, traumatic injury, tinea sore. From cholla stem be because its nature and flavor micro-sweet, it is nontoxic, control palpitation, have blood in stool, hemorrhoid blood, laryngalgia, malignant boil swells.Drawn from tripe is because its property Acrid-sweet flavor, temperature is poisonous, enters lung, spleen two passes through, and has tonifying Qi establishing-Yang, the function of nourishing heart hemostasis, controls impotence, leukorrhea, rheumatic heart Disease, consumptive disease chronic cough, knife wound bleeding.It is because its property slightly sweet flavor from smilax, puts down, enter liver, stomach, there is removing toxic substances, dehumidify, Li Guan The function of section, control syphilis, stranguria with turbid discharge, muscles and bones contraction pain, tinea pedis, furunculosis, carbuncle swells, scrofula.From Rubus parvifolius, alias:Red plum disappears, March Bubble, its is bitter in taste, puckery, cool, has clearing heat and cooling blood, dissipating bind, analgesic, the function of inducing diuresis to remove edema, cure cold heating, abscess of throat, coughs up Blood, spit blood, dysentery, enteritis, hepatitis, hepatosplenomegaly, nephritic dropsy, urinary infection, calculus, irregular menstruation, leukorrhea, rheumatic bone Bitterly, treating swelling and pain by traumatic injury;Eczema, dermatitis are controlled in external application.From cymbopogon distans worked hard because of its nature and flavor, it is cool, there is inducing diaphoresis, dampness removing, relieving asthma, only The function of cough, the heat that cures the wound flu, gonorrhoea, rheumatism muscles and bones are ached, chronic bronchitis.It is because its nature and flavor is pungent from Chinese prickly ash, temperature, has Poison, enter spleen, lung, kidney channel, there is warming spleen and stomach for dispelling cold, dehumidify, analgesic, desinsection, solution fish raw meat poison, control having indigestion and stop drinking, trusted subordinate's crymodynia, vomiting, Oh, cough with dyspnea, wind-cold-dampness arthralgia, diarrhea, dysentery, colic, dentalgia, roundworm disease, enterobiasis, pruritus vulvae, sore scabies.It is from Rhizoma Sparganii Because its nature and flavor toil, to put down, enter liver, the spleen channel, have blood-breaking, promoting the circulation of qi, disperse accumulations, the function of analgesic, control lumps in the chest and abdomen, qi and blood coagulates band, Trusted subordinate's pain, swollen pain under the side of body, Amenorrhea, postpartum blood stasis stomachache, traumatic injury, sore swells are hard.From curcuma zedoary be because its nature and flavor it is pungent, Bitter, temperature, Return liver, the spleen channel have a promoting the circulation of qi blood-breaking, the function , Zhi abdominal lump of mass in abdomen of Xiao Ji Zhi Tong, blood stasis closed, dyspepsia distending pain, and bruise swells Bitterly, early cervical carcinoma.It is because its cold in nature, bitter from sowthistle, has clearing heat and detoxicating, the function of qi-restoratives cough-relieving, controls bacillary dysentery, larynx Inflammation, weakness cough, internal piles abjection, leukorrhea.Be from Chinese munronia herb because its is mild-natured, it is lightly seasoned, it is nontoxic, control the cough of five consumptive diseases, fall Beat damage and rheumatism, external application nameless sores or boils.It is because the bitter micro-pungent of its nature and flavor from runcinate knotweed herb, trembles with fear, there is clearing heat and detoxicating, promoting blood circulation The function of detumescence, control dysentery, leukorrhea, blood-head headache, uterine bleeding, Amenorrhea, acute mastitis boil, traumatic injury.Be from turnip seed because Its nature and flavor is pungent, puts down, enter liver, spleen two pass through, and have improving eyesight, heat-clearing, the function of dampness removing, control glaucoma, and mesh is dark, jaundice, dysentery, and urine is not Profit.It is because its nature and flavor is light from crotalaria seesiliflora, puts down have nourishing YIN for benefiting the kidney, the function of anticancer, control cutaneum carcinoma, tinnitus is deaf, the head Dizziness.It is because its nature and flavor sweet acid from carambola, trembles with fear, have heat-clearing, promote the production of body fluid, Li Shui, the function of removing toxic substances controls cough due to wind-heat evil, polydipsia, Aphthous stomatitis, toothache, urolithiasis.It is because its is bitter in taste from berba aristolochiae mollissimae, puts down, control rheumatic arthritis, suffer from abdominal pain, malaria, carbuncle swells.From bamboo Section pseudo-ginseng is because its nature and flavor sweetness and bitterness, and temperature, enter liver, spleen two pass through, and has cough-relieving, resolving sputum, dissipates the stasis of blood, the function of promoting blood circulation, control cough ant phlegm, Over-strained hemoptysis, traumatic injury, carbuncle swells, traumatism and bleeding.
Embodiment
The drug dose of prescription of the present invention is also that inventor show that the dosage of each component is under by largely groping to summarize Stating all has the effect of preferable in weight range:
9-13 grams of leech, 15-20 grams of ground bettle, 10-15 grams of gecko, 1-2 grams of borneol, 25-35 grams of giant knotweed, 25-35 grams of marine alga, elder brother 25-35 grams of cloth, 10-15 grams of red halloysite, 15-25 grams of celery, 10-20 grams of the capsule of weeping forsythia, 10-15 grams of almond, 10-15 grams of japanese plum root-bark, spider 10-15 grams of spider perfume (or spice), 10-15 grams of fortune firethorn fruit, 25-35 grams of imperial pearl, 2-6 grams of skink, 0.3-0.5 grams of buchanan cryptolepis root, cayropteris incana 10-20 Gram, 10-20 grams of radix polygonati officinalis, 15-25 grams of Blumea balsamifera, 10-15 grams of cholla stem, tripe draw 10-20 grams, 25-35 grams of smilax, Rubus parvifolius 10- 15 grams, 25-35 grams of cymbopogon distans, 3-9 grams of Chinese prickly ash, 10-20 grams of Rhizoma Sparganii, 10-20 grams of curcuma zedoary, 10-20 grams of sowthistle, Chinese munronia herb 10-20 grams, 10-20 grams of runcinate knotweed herb, 55-65 grams of turnip seed, 25-35 grams of crotalaria seesiliflora, 55-65 grams of carambola, 10-20 grams of berba aristolochiae mollissimae, 10-15 grams of Rhizoma Panacis japonici.
Preferably:
11 grams of leech, 18 grams of ground bettle, 12 grams of gecko, 1.5 grams of borneol, 30 grams of giant knotweed, 30 grams of marine alga, 30 grams of kelp, red halloysite 12 grams, 20 grams of celery, 15 grams of the capsule of weeping forsythia, 12 grams of almond, 12 grams of japanese plum root-bark, 12 grams of jatamans valeriana rhizome, 12 grams of fortune firethorn fruit, 30 grams of imperial pearl, stone Imperial 4 grams of son, 0.3 gram of buchanan cryptolepis root, 15 grams of cayropteris incana, 15 grams of radix polygonati officinalis, 20 grams of Blumea balsamifera, 12 grams of cholla stem, tripe draw 15 grams, smilax 30 grams, 12 grams of Rubus parvifolius, 30 grams of cymbopogon distans, 6 grams of Chinese prickly ash, 15 grams of Rhizoma Sparganii, 15 grams of curcuma zedoary, 15 grams of sowthistle, 15 grams of Chinese munronia herb, 15 grams of runcinate knotweed herb, 60 grams of turnip seed, 30 grams of crotalaria seesiliflora, 60 grams of carambola, 15 grams of berba aristolochiae mollissimae, 12 grams of Rhizoma Panacis japonici.
The preparation method of medicine of the present invention is as follows:
First, stock up
1st, leech:Clean, it is vexed soft, segment, dry;
2nd, ground bettle:Take crude drug, cleaning, drying;
3rd, gecko:Crude drug is taken, removes impurity;
4th, borneol:Original is used as medicine;
5th, giant knotweed:Crude drug is taken, impurity is removed, cleaning, drying, splits broken;
6th, marine alga:Impurity is picked, is slightly floated with water, is slightly dried in the air, segment, dry;
7th, kelp:Impurity is picked, is rinsed with water, wide silk is cut into, dries;
8th, red halloysite:Pick soil, impurity;
9th, celery:Net impurity is picked, is dried;
10th, the capsule of weeping forsythia:Net impurity is picked, stranding is opened, except discarding stalk;
11st, almond:Net impurity is picked, puts in boiling water and slightly boils, skin microcreping of waiting, which rises, to be pulled out, is soaked in cold water, is sloughed kind of a skin, dry, and is winnowed with a dustpan net;
12nd, japanese plum root-bark:Whole year can excavate;
13rd, jatamans valeriana rhizome:Clean, cut off fibrous root, cut into slices, dry;
14th, fortune firethorn fruit:Pluck, dry during autumn fruit maturation;
15th, Long Zhu:The 7-8 months harvest;
16th, skink:Catch, put to death between summer, autumn, except internal organ, put ventilation drying;
17th, buchanan cryptolepis root:Net impurity is picked, is dried;
18th, cayropteris incana:Summer, autumn harvesting, segment, are dried;
19th, radix polygonati officinalis:Impurity is removed, cleans soil, vexed profit is uniform to inside and outside humidity, section, dries;
20th, Blumea balsamifera:Whole year can adopt, and pick net impurity, dry;
21st, cholla stem:The 4-8 months, when cactus juice is full, the luxuriant cactus tree of growth selection, crust is cut, makes its slurry Liquid is excessive, is collected after condensing;
22nd, tripe is drawn:Dug after spring sends out before seedling, or seedling stem is withered after autumn and adopt root, removed stem seedling, tremble net silt, dry;
23rd, smilax:Floated with water logging, summer changes water 1 time daily, and spring, every 2 days of autumn change water 1 time, and winter can change water on the 3rd 1 time, prevents It is only smelly, untill soaking, pull section out, dry in time;
24th, Rubus parvifolius:Autumn uproots, and summer and autumn adopt cauline leaf, dries;
25th, cymbopogon distans:Aerial part is extracted at the beginning of autumn late summer, is dried;
26th, Chinese prickly ash:Remove carpopodium and seed green pepper mesh, put fried in pot to make sound, oil goes out, take out, cool;
27th, Rhizoma Sparganii:Net impurity is picked, is soaked in water, pulls out and runs through, cuts into slices, dries;
28th, curcuma zedoary:Crude drug is taken, impurity is removed, size stepping, cleans, slightly soak, take out, run through, shave, dry, weed out Chip;
29th, sowthistle:Spring uproops before blooming, and cleans, dries;
30th, Chinese munronia herb:Net impurity is picked, is dried;
31st, runcinate knotweed herb:Summer, autumn harvesting;
32nd, turnip seed:Complete stool is extracted when late spring, early summer seed maturity, lower seed is rubbed with the hands, removes impurity, dry;
33rd, crotalaria seesiliflora:Tapped during autumn fruit maturation, remove impurity, dry;
34th, carambola:Fresh carambola is taken, cleans, dries;
35th, berba aristolochiae mollissimae:May harvests before blooming, and dries;
36th, Rhizoma Panacis japonici:Take rhizome the 9-10 months, remove fibrous root, clean soil, dry or a heatable brick bed is done.
2nd, prepare
1st, water intaking leech, ground bettle, gecko, borneol, skink are placed in porcelain broad-mouthed receptacle for holding liquid and are pounded broken medicinal powder;
2nd, by the giant knotweed cooked, marine alga, kelp, red halloysite, celery, the capsule of weeping forsythia, almond, japanese plum root-bark, jatamans valeriana rhizome, fortune firethorn fruit, dragon Pearl, buchanan cryptolepis root, cayropteris incana, radix polygonati officinalis, Blumea balsamifera, cholla stem, tripe drawing, smilax, Rubus parvifolius, cymbopogon distans, Chinese prickly ash, Rhizoma Sparganii, curcuma zedoary, lettuce Mai dishes, Chinese munronia herb, runcinate knotweed herb, turnip seed, crotalaria seesiliflora, carambola, berba aristolochiae mollissimae, Rhizoma Panacis japonici wear into broken medicinal powder;
3rd, separately take 300 grams of sesame oil to be placed in decocting container, boil 15 minutes, add the above-mentioned medicinal powder ground, intense fire is boiled to the dregs of a decoction During all black, filter off except the dregs of a decoction, then 400 grams of the medicinal powder smashed to pieces and refined honey are added after 48 minutes with being cooked by slow fire, mix Uniformly, continue, with being cooked by slow fire 38 minutes, to remove fire and treat temperature, the big piller of mung bean is made, put shady place and dry in the shade and produce.
Leech blood-breaking in prescription, by the stasis of blood, stimulate the menstrual flow, ground bettle has broken stasis of blood blood, and both functions of continuous muscles and bones are monarch drug in a prescription;Marine alga is soft Heavily fortified point, dissolving phlegm, Li Shui, expel the heat-evil, celery has a calming liver and clearing heat, the function of expelling wind and removing dampness, with gecko, borneol, giant knotweed, kelp, red halloysite, The capsule of weeping forsythia is ministerial drug, and ten taste medicines play broken stasis of blood blood, stimulated the menstrual flow, the effect of calming liver and clearing heat, expelling wind and removing dampness jointly, treats atherosclerosis Effect is comprehensive, and with broken stasis of blood blood, stimulate the menstrual flow, based on calming liver and clearing heat, can effect a permanent cure;Japanese plum root-bark, which has, drops inverse, eliminating dampness, clearing heat and detoxicating function It is adjutant with almond, jatamans valeriana rhizome, fortune firethorn fruit, Long Zhu, skink, buchanan cryptolepis root, cayropteris incana, radix polygonati officinalis, Blumea balsamifera, cholla stem;Agriculture is lucky Profit has nourishing YIN for benefiting the kidney, and the function of anticancer is to take stopgap measures with remaining all medicines to make medicine.
Medicine of the present invention have broken stasis of blood blood, stimulate the menstrual flow, calming liver and clearing heat, nourishing YIN for benefiting the kidney, clearing heat and detoxicating function, it is dynamic for treating Pulse atherosclerosis are quick, good effect.
The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these experiments include medicine of the present invention Animal toxicity test and clinical observation on the therapeutic effect experiment.
The animal toxicity test of [test example 1] medicine of the present invention
Rabbit 30 is taken, male and female dual-purpose, 2.0-2.5kg of body weight, is divided to two groups, every group 15, one of which is tested for overdose Group, another group is normal amount test group.Super quantity group is 0.3g/kg, normal amount 0.1g/kg, and administering mode is given for administration by gavage Medicine, twice daily, 7 days are even served, the reaction of observation administration daily, the results showed that two groups of rabbit activities, diet are normal, and medicine is without bad Toxic side effect.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1st, general information
Accept out-patient totally 62 for medical treatment.
2nd, diagnostic criteria
The symptom of atherosclerosis includes:Dizzy headache, failure of memory, sleep-disorder.
3rd, treatment method
From said medicine, taken to patient, each 5-6 grams, it is early, middle and late daily it is each once, 15 days as one therapeutic course, continuous clothes With 3 courses for the treatment of.
4th, efficacy assessment standard
It is effective:Symptoms of atherosclerosis disappears, and recovers normal, recovery from illness;
Take a turn for the better:Patient's dizziness headache, failure of memory, the phenomenon of sleep-disorder mitigate, and symptoms of atherosclerosis is clearly better, Progressively recover;
It is invalid:Improvement standard person is not reached.
5th, treatment results(It see the table below):
In above-mentioned treatment, with drug therapy atherosclerotic 62 of the present invention, as a result effective 53, obvious effective rate is 85.49%, take a turn for the better 7, improvement rate 11.29%, invalid 2, total effective rate 96.78%.

Claims (3)

  1. A kind of 1. medicine for treating atherosclerosis, it is characterised in that:It is made up of the bulk drug in following weight range:
    9-13 grams of leech, 15-20 grams of ground bettle, 10-15 grams of gecko, 1-2 grams of borneol, 25-35 grams of giant knotweed, 25-35 grams of marine alga, elder brother 25-35 grams of cloth, 10-15 grams of red halloysite, 15-25 grams of celery, 10-20 grams of the capsule of weeping forsythia, 10-15 grams of almond, 10-15 grams of japanese plum root-bark, spider 10-15 grams of spider perfume (or spice), 10-15 grams of fortune firethorn fruit, 25-35 grams of imperial pearl, 2-6 grams of skink, 0.3-0.5 grams of buchanan cryptolepis root, cayropteris incana 10-20 Gram, 10-20 grams of radix polygonati officinalis, 15-25 grams of Blumea balsamifera, 10-15 grams of cholla stem, tripe draw 10-20 grams, 25-35 grams of smilax, Rubus parvifolius 10- 15 grams, 25-35 grams of cymbopogon distans, 3-9 grams of Chinese prickly ash, 10-20 grams of Rhizoma Sparganii, 10-20 grams of curcuma zedoary, 10-20 grams of sowthistle, Chinese munronia herb 10-20 grams, 10-20 grams of runcinate knotweed herb, 55-65 grams of turnip seed, 25-35 grams of crotalaria seesiliflora, 55-65 grams of carambola, 10-20 grams of berba aristolochiae mollissimae, 10-15 grams of Rhizoma Panacis japonici.
  2. 2. medicine according to claim 1, wherein the dosage of each bulk drug is:
    11 grams of leech, 18 grams of ground bettle, 12 grams of gecko, 1.5 grams of borneol, 30 grams of giant knotweed, 30 grams of marine alga, 30 grams of kelp, red halloysite 12 grams, 20 grams of celery, 15 grams of the capsule of weeping forsythia, 12 grams of almond, 12 grams of japanese plum root-bark, 12 grams of jatamans valeriana rhizome, 12 grams of fortune firethorn fruit, 30 grams of imperial pearl, stone Imperial 4 grams of son, 0.3 gram of buchanan cryptolepis root, 15 grams of cayropteris incana, 15 grams of radix polygonati officinalis, 20 grams of Blumea balsamifera, 12 grams of cholla stem, tripe draw 15 grams, smilax 30 grams, 12 grams of Rubus parvifolius, 30 grams of cymbopogon distans, 6 grams of Chinese prickly ash, 15 grams of Rhizoma Sparganii, 15 grams of curcuma zedoary, 15 grams of sowthistle, 15 grams of Chinese munronia herb, 15 grams of runcinate knotweed herb, 60 grams of turnip seed, 30 grams of crotalaria seesiliflora, 60 grams of carambola, 15 grams of berba aristolochiae mollissimae, 12 grams of Rhizoma Panacis japonici.
  3. 3. the preparation method of medicine according to claim 1 or claim 2, it is characterised in that:It comprises the following steps:
    (One)Stock
    (1)Leech:Clean, it is vexed soft, segment, dry;
    (2)Ground bettle:Take crude drug, cleaning, drying;
    (3)Gecko:Crude drug is taken, removes impurity;
    (4)Borneol:Original is used as medicine;
    (5)Giant knotweed:Crude drug is taken, impurity is removed, cleaning, drying, splits broken;
    (6)Marine alga:Impurity is picked, is slightly floated with water, is slightly dried in the air, segment, dry;
    (7)Kelp:Impurity is picked, is rinsed with water, wide silk is cut into, dries;
    (8)Red halloysite:Pick soil, impurity;
    (9)Celery:Net impurity is picked, is dried;
    (10)The capsule of weeping forsythia:Net impurity is picked, stranding is opened, except discarding stalk;
    (11)Almond:Net impurity is picked, puts in boiling water and slightly boils, skin microcreping of waiting, which rises, to be pulled out, is soaked in cold water, is sloughed kind of a skin, dry, winnow with a dustpan Only;
    (12)Japanese plum root-bark:Whole year can excavate;
    (13)Jatamans valeriana rhizome:Clean, cut off fibrous root, cut into slices, dry;
    (14)Fortune firethorn fruit:Pluck, dry during autumn fruit maturation;
    (15)Long Zhu:The 7-8 months harvest;
    (16)Skink:Catch, put to death between summer, autumn, except internal organ, put ventilation drying;
    (17)Buchanan cryptolepis root:Net impurity is picked, is dried;
    (18)Cayropteris incana:Summer, autumn harvesting, segment, are dried;
    (19)Radix polygonati officinalis:Impurity is removed, cleans soil, vexed profit is uniform to inside and outside humidity, section, dries;
    (20)Blumea balsamifera:Whole year can adopt, and pick net impurity, dry;
    (21)Cholla stem:The 4-8 months, when cactus juice is full, the luxuriant cactus tree of growth selection, crust is cut, makes it Slurries are excessive, collected after condensing;
    (22)Tripe is drawn:Dug after spring sends out before seedling, or seedling stem is withered after autumn and adopt root, removed stem seedling, tremble net silt, dry;
    (23)Smilax:Floated with water logging, summer changes water 1 time daily, and spring, every 2 days of autumn change water 1 time, and winter can change water on the 3rd 1 time, prevents It is only smelly, untill soaking, pull section out, dry in time;
    (24)Rubus parvifolius:Autumn uproots, and summer and autumn adopt cauline leaf, dries;
    (25)Cymbopogon distans:Aerial part is extracted at the beginning of autumn late summer, is dried;
    (26)Chinese prickly ash:Remove carpopodium and seed green pepper mesh, put fried in pot to make sound, oil goes out, take out, cool;
    (27)Rhizoma Sparganii:Net impurity is picked, is soaked in water, pulls out and runs through, cuts into slices, dries;
    (28)Curcuma zedoary:Crude drug is taken, impurity is removed, size stepping, cleans, slightly soak, take out, run through, shave, dry, sieve Remove chip;
    (29)Sowthistle:Spring uproops before blooming, and cleans, dries;
    (30)Chinese munronia herb:Net impurity is picked, is dried;
    (31)Runcinate knotweed herb:Summer, autumn harvesting;
    (32)Turnip seed:Complete stool is extracted when late spring, early summer seed maturity, lower seed is rubbed with the hands, removes impurity, dry;
    (33)Crotalaria seesiliflora:Tapped during autumn fruit maturation, remove impurity, dry;
    (34)Carambola:Fresh carambola is taken, cleans, dries;
    (35)Berba aristolochiae mollissimae:May harvests before blooming, and dries;
    (36)Rhizoma Panacis japonici:Take rhizome the 9-10 months, remove fibrous root, clean soil, dry or a heatable brick bed is done;
    (Two)Prepare
    (1)Water intaking leech, ground bettle, gecko, borneol, skink are placed in porcelain broad-mouthed receptacle for holding liquid and are pounded broken medicinal powder;
    (2)By the giant knotweed cooked, marine alga, kelp, red halloysite, celery, the capsule of weeping forsythia, almond, japanese plum root-bark, jatamans valeriana rhizome, fortune firethorn fruit, dragon Pearl, buchanan cryptolepis root, cayropteris incana, radix polygonati officinalis, Blumea balsamifera, cholla stem, tripe drawing, smilax, Rubus parvifolius, cymbopogon distans, Chinese prickly ash, Rhizoma Sparganii, curcuma zedoary, lettuce Mai dishes, Chinese munronia herb, runcinate knotweed herb, turnip seed, crotalaria seesiliflora, carambola, berba aristolochiae mollissimae, Rhizoma Panacis japonici wear into broken medicinal powder;
    (3)Separately take 300 grams of sesame oil to be placed in decocting container, boil 15 minutes, add the above-mentioned medicinal powder ground, intense fire is boiled to the dregs of a decoction During all black, filter off except the dregs of a decoction, then 400 grams of the medicinal powder smashed to pieces and refined honey are added after 48 minutes with being cooked by slow fire, mix Uniformly, continue, with being cooked by slow fire 38 minutes, to remove fire and treat temperature, the big piller of mung bean is made, put shady place and dry in the shade and produce.
CN201711087890.4A 2017-11-08 2017-11-08 A kind of medicine for treating atherosclerosis and preparation method thereof Pending CN107596280A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102600255A (en) * 2012-03-29 2012-07-25 周柳池 Coronary disease treatment capsule
CN104274549A (en) * 2013-07-03 2015-01-14 河北以岭医药研究院有限公司 Application of traditional Chinese medicine composition to prepare medicines for preventing atherosclerosis
US9744196B2 (en) * 2012-10-24 2017-08-29 N2 Pharmaceuticals Ltd Composition for parenteral administration, method for producing and method use thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102600255A (en) * 2012-03-29 2012-07-25 周柳池 Coronary disease treatment capsule
US9744196B2 (en) * 2012-10-24 2017-08-29 N2 Pharmaceuticals Ltd Composition for parenteral administration, method for producing and method use thereof
CN104274549A (en) * 2013-07-03 2015-01-14 河北以岭医药研究院有限公司 Application of traditional Chinese medicine composition to prepare medicines for preventing atherosclerosis

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
周国雄: "《中西医结合老年病治疗学》", 31 July 1993, 广东科技出版社 *
申斌等: "自拟颈斑消贴膏贴敷人迎穴对颈动脉粥样硬化斑块的影响", 《中医药导报》 *

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Application publication date: 20180119