CN1208045C - 含有脂肪酸酰胺、唑类化合物和视黄醇或视黄酯的护肤组合物 - Google Patents
含有脂肪酸酰胺、唑类化合物和视黄醇或视黄酯的护肤组合物 Download PDFInfo
- Publication number
- CN1208045C CN1208045C CNB971129738A CN97112973A CN1208045C CN 1208045 C CN1208045 C CN 1208045C CN B971129738 A CNB971129738 A CN B971129738A CN 97112973 A CN97112973 A CN 97112973A CN 1208045 C CN1208045 C CN 1208045C
- Authority
- CN
- China
- Prior art keywords
- retinol
- fatty acid
- acid
- skin
- retinyl ester
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 title claims abstract description 114
- 235000020944 retinol Nutrition 0.000 title claims abstract description 106
- 239000011607 retinol Substances 0.000 title claims abstract description 105
- 229960003471 retinol Drugs 0.000 title claims abstract description 105
- 239000000194 fatty acid Substances 0.000 title claims abstract description 45
- 235000014113 dietary fatty acids Nutrition 0.000 title claims abstract description 44
- 229930195729 fatty acid Natural products 0.000 title claims abstract description 44
- 150000004665 fatty acids Chemical class 0.000 title claims abstract description 42
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- WWDMJSSVVPXVSV-YCNIQYBTSA-N retinyl ester Chemical compound CC1CCCC(C)(C)C1\C=C\C(\C)=C\C=C\C(\C)=C\C(O)=O WWDMJSSVVPXVSV-YCNIQYBTSA-N 0.000 title abstract description 55
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 claims abstract description 43
- 229960001727 tretinoin Drugs 0.000 claims abstract description 40
- OWEGWHBOCFMBLP-UHFFFAOYSA-N 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one Chemical compound C1=CN=CN1C(C(=O)C(C)(C)C)OC1=CC=C(Cl)C=C1 OWEGWHBOCFMBLP-UHFFFAOYSA-N 0.000 claims description 25
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- OCAPBUJLXMYKEJ-UHFFFAOYSA-N 1-[biphenyl-4-yl(phenyl)methyl]imidazole Chemical compound C1=NC=CN1C(C=1C=CC(=CC=1)C=1C=CC=CC=1)C1=CC=CC=C1 OCAPBUJLXMYKEJ-UHFFFAOYSA-N 0.000 claims description 19
- 229960002206 bifonazole Drugs 0.000 claims description 19
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- 238000000034 method Methods 0.000 claims description 11
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- 125000002252 acyl group Chemical group 0.000 claims description 7
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- 125000002811 oleoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])/C([H])=C([H])\C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 6
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- BYBLEWFAAKGYCD-UHFFFAOYSA-N Miconazole Chemical compound ClC1=CC(Cl)=CC=C1COC(C=1C(=CC(Cl)=CC=1)Cl)CN1C=NC=C1 BYBLEWFAAKGYCD-UHFFFAOYSA-N 0.000 claims description 3
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- LEZWWPYKPKIXLL-UHFFFAOYSA-N 1-{2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl}imidazole Chemical compound C1=CC(Cl)=CC=C1COC(C=1C(=CC(Cl)=CC=1)Cl)CN1C=NC=C1 LEZWWPYKPKIXLL-UHFFFAOYSA-N 0.000 claims description 2
- 239000003581 cosmetic carrier Substances 0.000 claims description 2
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- 125000001236 palmitoleoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])/C([H])=C([H])\C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 2
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- 125000000946 retinyl group Chemical group [H]C([*])([H])/C([H])=C(C([H])([H])[H])/C([H])=C([H])/C([H])=C(C([H])([H])[H])/C([H])=C([H])/C1=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
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- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 7
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- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 6
- VYGQUTWHTHXGQB-FFHKNEKCSA-N Retinol Palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-FFHKNEKCSA-N 0.000 description 6
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- 238000002360 preparation method Methods 0.000 description 6
- QGNJRVVDBSJHIZ-QHLGVNSISA-N retinyl acetate Chemical compound CC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C QGNJRVVDBSJHIZ-QHLGVNSISA-N 0.000 description 6
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- 230000000474 nursing effect Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 150000004987 o-phenylenediamines Chemical class 0.000 description 1
- 239000007764 o/w emulsion Substances 0.000 description 1
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 239000003605 opacifier Substances 0.000 description 1
- DXGLGDHPHMLXJC-UHFFFAOYSA-N oxybenzone Chemical compound OC1=CC(OC)=CC=C1C(=O)C1=CC=CC=C1 DXGLGDHPHMLXJC-UHFFFAOYSA-N 0.000 description 1
- 229960001173 oxybenzone Drugs 0.000 description 1
- 125000004430 oxygen atom Chemical group O* 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 102000013415 peroxidase activity proteins Human genes 0.000 description 1
- 108040007629 peroxidase activity proteins Proteins 0.000 description 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- ZPWFUIUNWDIYCJ-UHFFFAOYSA-N propan-2-yl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC(C)C ZPWFUIUNWDIYCJ-UHFFFAOYSA-N 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 208000029561 pustule Diseases 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000001172 regenerating effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- YGSDEFSMJLZEOE-UHFFFAOYSA-M salicylate Chemical compound OC1=CC=CC=C1C([O-])=O YGSDEFSMJLZEOE-UHFFFAOYSA-M 0.000 description 1
- 229960001860 salicylate Drugs 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 208000008742 seborrheic dermatitis Diseases 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 229910000077 silane Inorganic materials 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 230000009759 skin aging Effects 0.000 description 1
- 230000036548 skin texture Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- WRPMUZXHQKAAIC-ZZEZOPTASA-N stearyl oleate Chemical compound CCCCCCCCCCCCCCCCCCOC(=O)CCCCCCC\C=C/CCCCCCCC WRPMUZXHQKAAIC-ZZEZOPTASA-N 0.000 description 1
- 239000004575 stone Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000001117 sulphuric acid Substances 0.000 description 1
- 235000011149 sulphuric acid Nutrition 0.000 description 1
- 239000011885 synergistic combination Substances 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- BORJONZPSTVSFP-UHFFFAOYSA-N tetradecyl 2-hydroxypropanoate Chemical compound CCCCCCCCCCCCCCOC(=O)C(C)O BORJONZPSTVSFP-UHFFFAOYSA-N 0.000 description 1
- 238000010257 thawing Methods 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 150000003573 thiols Chemical class 0.000 description 1
- WBYWAXJHAXSJNI-VOTSOKGWSA-M trans-cinnamate Chemical compound [O-]C(=O)\C=C\C1=CC=CC=C1 WBYWAXJHAXSJNI-VOTSOKGWSA-M 0.000 description 1
- ZDPHROOEEOARMN-UHFFFAOYSA-N undecanoic acid Chemical compound CCCCCCCCCCC(O)=O ZDPHROOEEOARMN-UHFFFAOYSA-N 0.000 description 1
- 229940005605 valeric acid Drugs 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 125000001834 xanthenyl group Chemical class C1=CC=CC=2OC3=CC=CC=C3C(C12)* 0.000 description 1
- 150000003751 zinc Chemical class 0.000 description 1
- OYWXIJJKRYRHIN-DNOYCTHFSA-L zinc;(2e,4e,6e,8e)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoate Chemical compound [Zn+2].[O-]C(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C.[O-]C(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OYWXIJJKRYRHIN-DNOYCTHFSA-L 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US638,074 | 1984-08-06 | ||
| US638074 | 1984-08-06 | ||
| US08/638,074 US5716627A (en) | 1996-04-25 | 1996-04-25 | Skin care compositions containing fatty acid amides, azoles, and retinol or retinyl ester |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1169854A CN1169854A (zh) | 1998-01-14 |
| CN1208045C true CN1208045C (zh) | 2005-06-29 |
Family
ID=24558543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB971129738A Expired - Lifetime CN1208045C (zh) | 1996-04-25 | 1997-04-25 | 含有脂肪酸酰胺、唑类化合物和视黄醇或视黄酯的护肤组合物 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5716627A (en:Method) |
| EP (1) | EP0803248B1 (en:Method) |
| JP (1) | JP3540913B2 (en:Method) |
| CN (1) | CN1208045C (en:Method) |
| AR (1) | AR006800A1 (en:Method) |
| AU (1) | AU709425B2 (en:Method) |
| BR (1) | BR9701946B1 (en:Method) |
| CA (1) | CA2202338C (en:Method) |
| DE (1) | DE69714900T2 (en:Method) |
| ES (1) | ES2181993T3 (en:Method) |
| ID (1) | ID17286A (en:Method) |
| IN (1) | IN189552B (en:Method) |
| MX (1) | MX9702920A (en:Method) |
| NZ (1) | NZ314561A (en:Method) |
| ZA (1) | ZA973150B (en:Method) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5747051A (en) * | 1996-09-27 | 1998-05-05 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing an amide of a hydroxy fatty acid and a retinoid |
| GB9918022D0 (en) * | 1999-07-30 | 1999-09-29 | Unilever Plc | Skin care composition |
| US6358517B1 (en) * | 1999-10-22 | 2002-03-19 | Unilever Home & Personal Care Usa, Division Of Conopco | Cosmetic compositions containing resveratrol and retinoids |
| US6261566B1 (en) * | 1999-10-22 | 2001-07-17 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Cosmetic compositions containing mulberry extract and retinoids |
| EP1227834A2 (en) * | 1999-11-10 | 2002-08-07 | Vlaams Interuniversitair Instituut voor Biotechnologie vzw. | Use of caspase-14 and caspase-14 modulators to diagnose and/or treat skin, eye and brain disorders |
| CA2412788C (en) * | 2000-06-30 | 2011-09-06 | Unilever Plc | Skin conditioning compositions containing compounds for mimicking the effect on skin of retinoic acid |
| US20020143059A1 (en) * | 2000-12-28 | 2002-10-03 | Sreekumar Pillai | Skin care product containing retinoids, retinoid booster and phytoestrogens in a dual compartment package |
| US6949247B2 (en) * | 2000-12-28 | 2005-09-27 | Unilever Home & Personal Care Usa Division Of Conopco, Inc. | Stable skin care compositions containing a retinoid and a retinoid booster system |
| DE60228713D1 (de) * | 2001-07-18 | 2008-10-16 | Unilever Nv | Zusammensetzungen für die behandlung von haaren und/oder kopfhaut |
| US20040242704A1 (en) | 2003-03-14 | 2004-12-02 | University Of Washington, Techtransfer - Invention Licensing | Stabilized mutant opsin proteins |
| US7494459B2 (en) * | 2003-06-26 | 2009-02-24 | Biophan Technologies, Inc. | Sensor-equipped and algorithm-controlled direct mechanical ventricular assist device |
| CN1988898B (zh) | 2004-06-18 | 2012-12-26 | 华盛顿大学 | 用于治疗视觉障碍的视黄醛衍生物及其使用方法 |
| US8715733B2 (en) * | 2004-07-23 | 2014-05-06 | DePuy Synthes Products, LLC | Enhanced adipose tissue |
| BRPI0908154A2 (pt) | 2008-02-11 | 2015-08-11 | Univ Washington | Métodos para o tratamento e a prevenção de disfunções retinianas relacionadas à idade |
| JP2011020958A (ja) * | 2009-07-16 | 2011-02-03 | Hakutsuru Shuzo Kk | シワ抑制用組成物 |
| MX2012003220A (es) | 2009-09-15 | 2012-08-03 | Quadra Logic Tech Inc | Formulaciones farmaceuticas que comprenden 9-cis-retinil esteres en un vehiculo de lipido. |
| JP6250389B2 (ja) | 2010-04-19 | 2017-12-20 | ノベリオン セラピューティクス インコーポレイテッド | 内因性レチノイド欠損に関連する視覚障害を治療する又は改善する治療計画及び治療方法 |
| US9055745B2 (en) | 2011-04-13 | 2015-06-16 | Natureza, Inc. | Compositions for internal and external insecticides, ovicides, repellents and wound healing |
| DE102011087320A1 (de) * | 2011-11-29 | 2013-05-29 | Henkel Ag & Co. Kgaa | Neuartige Wirkstoffkombination zur effizienten Anti-Faltenwirkung |
| DE102011087319A1 (de) | 2011-11-29 | 2013-05-29 | Henkel Ag & Co. Kgaa | Kosmetische Verwendung von Climbazol |
| ES2378028B1 (es) * | 2012-02-22 | 2013-02-18 | Ignacio Umbert Millet | Composición cosmética para el rejuvenecimiento de la piel y procedimiento y usos correspondientes |
| AU2013232697B2 (en) | 2012-03-01 | 2017-10-19 | Eluminex Biosciences (Suzhou) Limited | Therapeutic regimens and methods for improving visual function in visual disorders associated with an endogenous retinoid deficiency |
| WO2014180600A1 (en) * | 2013-05-07 | 2014-11-13 | Unilever Plc | Use of climbazole |
| US9833402B2 (en) | 2014-01-27 | 2017-12-05 | Conopco, Inc. | Composition |
| CN106714792A (zh) * | 2014-08-08 | 2017-05-24 | R·米利亚乔 | 用于治疗炎症性和过敏性病理学的脂肪酸和十六酰胺乙醇的混合物 |
| CN105230617B (zh) * | 2015-09-25 | 2017-05-10 | 浙江大学 | 亚油酰乙醇胺在提高植物灰霉病和细菌性叶斑病抗性中的应用 |
| CN105900981B (zh) * | 2016-04-27 | 2018-03-16 | 浙江大学 | 亚油酰乙醇胺在提高植物黄化曲叶病毒病抗性中的应用 |
| BR102018005599A2 (pt) * | 2018-03-21 | 2019-10-08 | Pedro Barboza Da Rocha | Composição cicatrizante, hidratante, umectante e emoliente para administração tópica em lesões de pele intertrigo, lesões de pele por incontinência urinária e fecal e outras lesões afins. |
| WO2021059281A1 (en) * | 2019-09-26 | 2021-04-01 | Sol-Gel Technologies Ltd. | Treatment of skin disorders with topical combination compositions comprising tapinarof and an additional ahr activator |
| CN115697290B (zh) | 2020-05-29 | 2025-02-25 | 联合利华知识产权控股有限公司 | 针对视黄酸前体具有增强的颜色稳定性的化妆品组合物 |
| WO2022253516A1 (en) | 2021-06-04 | 2022-12-08 | Unilever Ip Holdings B.V. | A cosmetic composition comprising a retinoid for providing antiaging benefits |
| WO2022268415A1 (en) | 2021-06-24 | 2022-12-29 | Unilever Ip Holdings B.V. | Cosmetic composition with enhanced color stability |
| WO2024132346A1 (en) | 2022-12-21 | 2024-06-27 | Unilever Ip Holdings B.V. | Oil-continuous cosmetic composition |
| WO2025140995A1 (en) | 2023-12-29 | 2025-07-03 | Unilever Ip Holdings B.V. | Cosmetic composition with enhanced color stability |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1126289A (en) * | 1966-05-12 | 1968-09-05 | Hoffmann La Roche | Water-dispersible water-free vitamin preparations and a process for the manufacture thereof |
| US4363815A (en) * | 1975-07-23 | 1982-12-14 | Yu Ruey J | Alpha hydroxyacids, alpha ketoacids and their use in treating skin conditions |
| US4380549A (en) * | 1975-07-23 | 1983-04-19 | Scott Eugene J Van | Topical treatment of dry skin |
| CA1241602A (en) * | 1984-02-23 | 1988-09-06 | Ortho Pharmaceutical Corporation | Antifungal aerosol solution |
| US4867971A (en) * | 1988-04-22 | 1989-09-19 | Colgate-Palmolive Company | Low pH shampoo containing climbazole |
| GB8814296D0 (en) * | 1988-06-16 | 1988-07-20 | Unilever Plc | Shampoo composition |
| CA2002859C (en) * | 1988-11-29 | 1998-12-29 | Jean P. F. Van Wauwe | Method of treating epithelial disorders |
| FR2644063B1 (fr) * | 1989-03-13 | 1991-06-14 | Fabre Pierre Cosmetique | Compositions dermatologiques et cosmetologiques a base d'alcoylcarboxamide et de sel de zinc utiles dans le traitement de la dermite seborrheique et/ou des troubles de la seborrhee |
| GB8910069D0 (en) * | 1989-05-03 | 1989-06-21 | Janssen Pharmaceutica Nv | Method of topically treating acne vulgaris |
| US5476852A (en) * | 1989-05-03 | 1995-12-19 | Janssen Pharmaceutica N.V. | Method of topically treating acne vulgaris, hyperkeratotic dermatoses, and photo-aging of the skin |
| US5348736A (en) * | 1989-06-21 | 1994-09-20 | Colgate-Palmolive Company | Stabilized hair-treating compositions |
| US5057501A (en) * | 1990-03-13 | 1991-10-15 | Dermatologic Research Corporation | Methods for treatment of papulosquamous and eczematous diseases |
| FR2666347B1 (fr) * | 1990-08-31 | 1992-12-11 | Oreal | Compositions de lavage a base de silicones et procede de mise en óoeuvre. |
| BR9200951A (pt) * | 1991-03-21 | 1992-11-17 | Hoffmann La Roche | Compostos, processo para sua producao,preparacoes farmaceuticas e uso |
| US5750570A (en) * | 1992-03-31 | 1998-05-12 | The Regents Of The University Of Michigan | Method of treatment of hyperpigmentation in black skin with retinoic acid and method of lightening black skin with retinoic acid |
| CA2123794C (en) * | 1992-06-17 | 1998-09-15 | William Michael Luke | Coolant compositions with reduced stinging |
| ES2136105T3 (es) * | 1992-08-04 | 1999-11-16 | Rhone Poulenc Rorer Gmbh | Preparacion farmaceutica y/o cosmetica. |
| GR1002207B (en) * | 1992-08-06 | 1996-03-27 | Johnson & Johnson Consumer | Skin care compositions containing imidazoles. |
| MX9303557A (es) * | 1992-08-06 | 1994-03-31 | Beta Pharm Co | Metodo para la administracion de un antiandrogeno, en particular, espironolactona, a traves de la piel. |
| DE4328871A1 (de) * | 1993-08-27 | 1995-03-02 | Beiersdorf Ag | Mittel gegen empfindliche, hyperreaktive Hautzustände, atopische Dermatiden, Pruritus, Psoriasis Prurigo, Photodermatosen und Ichthyosis |
| WO1995017175A1 (en) * | 1993-12-23 | 1995-06-29 | The Procter & Gamble Company | Antimicrobial wipe compositions |
| US5536740A (en) * | 1995-06-01 | 1996-07-16 | Elizabeth Arden Company, Division Of Conopco, Inc. | Skin care compositions containing dimethyl imidazolidinone and retinol or retinyl ester |
-
1996
- 1996-04-25 US US08/638,074 patent/US5716627A/en not_active Expired - Lifetime
-
1997
- 1997-04-09 AU AU19018/97A patent/AU709425B2/en not_active Ceased
- 1997-04-09 NZ NZ314561A patent/NZ314561A/xx not_active IP Right Cessation
- 1997-04-10 CA CA002202338A patent/CA2202338C/en not_active Expired - Lifetime
- 1997-04-10 ES ES97302459T patent/ES2181993T3/es not_active Expired - Lifetime
- 1997-04-10 DE DE69714900T patent/DE69714900T2/de not_active Expired - Lifetime
- 1997-04-10 EP EP97302459A patent/EP0803248B1/en not_active Expired - Lifetime
- 1997-04-14 ZA ZA973150A patent/ZA973150B/xx unknown
- 1997-04-15 IN IN226BO1997 patent/IN189552B/en unknown
- 1997-04-22 MX MX9702920A patent/MX9702920A/es unknown
- 1997-04-23 ID IDP971348A patent/ID17286A/id unknown
- 1997-04-23 AR ARP970101637A patent/AR006800A1/es active IP Right Grant
- 1997-04-24 JP JP10759597A patent/JP3540913B2/ja not_active Expired - Lifetime
- 1997-04-25 BR BRPI9701946-1A patent/BR9701946B1/pt active IP Right Grant
- 1997-04-25 CN CNB971129738A patent/CN1208045C/zh not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP3540913B2 (ja) | 2004-07-07 |
| DE69714900D1 (de) | 2002-10-02 |
| BR9701946A (pt) | 1998-09-15 |
| US5716627A (en) | 1998-02-10 |
| DE69714900T2 (de) | 2002-12-19 |
| CA2202338C (en) | 2004-11-23 |
| EP0803248A3 (en) | 1997-12-17 |
| AU1901897A (en) | 1997-10-30 |
| BR9701946B1 (pt) | 2010-11-03 |
| EP0803248A2 (en) | 1997-10-29 |
| ES2181993T3 (es) | 2003-03-01 |
| CN1169854A (zh) | 1998-01-14 |
| MX9702920A (es) | 1998-04-30 |
| EP0803248B1 (en) | 2002-08-28 |
| JPH1036248A (ja) | 1998-02-10 |
| AU709425B2 (en) | 1999-08-26 |
| NZ314561A (en) | 1999-02-25 |
| IN189552B (en:Method) | 2003-03-29 |
| CA2202338A1 (en) | 1997-10-25 |
| ID17286A (id) | 1997-12-18 |
| AR006800A1 (es) | 1999-09-29 |
| ZA973150B (en) | 1998-10-04 |
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