CN1198793C - 甲基文拉法辛的醚 - Google Patents
甲基文拉法辛的醚 Download PDFInfo
- Publication number
- CN1198793C CN1198793C CNB008161496A CN00816149A CN1198793C CN 1198793 C CN1198793 C CN 1198793C CN B008161496 A CNB008161496 A CN B008161496A CN 00816149 A CN00816149 A CN 00816149A CN 1198793 C CN1198793 C CN 1198793C
- Authority
- CN
- China
- Prior art keywords
- formula
- compound
- alkyl
- acceptable salt
- hydrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (5)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44826899A | 1999-11-24 | 1999-11-24 | |
US09/448,268 | 1999-11-24 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNA2004100882450A Division CN1636559A (zh) | 1999-11-24 | 2000-11-21 | 甲基文拉法辛的醚 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1399626A CN1399626A (zh) | 2003-02-26 |
CN1198793C true CN1198793C (zh) | 2005-04-27 |
Family
ID=23779642
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB008161496A Expired - Fee Related CN1198793C (zh) | 1999-11-24 | 2000-11-21 | 甲基文拉法辛的醚 |
CNA2004100882450A Pending CN1636559A (zh) | 1999-11-24 | 2000-11-21 | 甲基文拉法辛的醚 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNA2004100882450A Pending CN1636559A (zh) | 1999-11-24 | 2000-11-21 | 甲基文拉法辛的醚 |
Country Status (25)
Country | Link |
---|---|
EP (1) | EP1232141B1 (zh) |
JP (1) | JP2003514889A (zh) |
KR (1) | KR100843991B1 (zh) |
CN (2) | CN1198793C (zh) |
AR (1) | AR024498A1 (zh) |
AT (1) | ATE278659T1 (zh) |
AU (1) | AU767835B2 (zh) |
BR (1) | BR0015795A (zh) |
CA (1) | CA2391288A1 (zh) |
CZ (1) | CZ20021816A3 (zh) |
DE (1) | DE60014693T2 (zh) |
DK (1) | DK1232141T3 (zh) |
ES (1) | ES2228636T3 (zh) |
HK (1) | HK1045835A1 (zh) |
HU (1) | HUP0203594A2 (zh) |
IL (2) | IL149531A0 (zh) |
MX (1) | MXPA02005174A (zh) |
NO (1) | NO20022446L (zh) |
NZ (1) | NZ519130A (zh) |
PL (1) | PL202846B1 (zh) |
PT (1) | PT1232141E (zh) |
SI (1) | SI1232141T1 (zh) |
TW (1) | TWI268919B (zh) |
WO (1) | WO2001038293A1 (zh) |
ZA (1) | ZA200204986B (zh) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6602911B2 (en) * | 2001-11-05 | 2003-08-05 | Cypress Bioscience, Inc. | Methods of treating fibromyalgia |
DK2621891T3 (da) * | 2010-10-01 | 2020-02-17 | Shan Dong Luye Pharm Co Ltd | Polymorfer af 4-[2-dimethylamino-1-(1 hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoathydrochlorid, fremgangsmåder til fremstilling og anvendelse deraf |
CN103319373B (zh) * | 2012-03-23 | 2017-09-19 | 浙江九洲药业股份有限公司 | 1‑[2‑氨基‑1‑(4‑苄氧基苯基)乙基]环己烷醇的制备方法及相关中间体 |
-
2000
- 2000-11-21 CN CNB008161496A patent/CN1198793C/zh not_active Expired - Fee Related
- 2000-11-21 AU AU17833/01A patent/AU767835B2/en not_active Ceased
- 2000-11-21 CA CA002391288A patent/CA2391288A1/en not_active Abandoned
- 2000-11-21 PT PT00980588T patent/PT1232141E/pt unknown
- 2000-11-21 AT AT00980588T patent/ATE278659T1/de not_active IP Right Cessation
- 2000-11-21 EP EP00980588A patent/EP1232141B1/en not_active Expired - Lifetime
- 2000-11-21 SI SI200030509T patent/SI1232141T1/xx unknown
- 2000-11-21 BR BR0015795-3A patent/BR0015795A/pt active Pending
- 2000-11-21 CZ CZ20021816A patent/CZ20021816A3/cs unknown
- 2000-11-21 JP JP2001539850A patent/JP2003514889A/ja not_active Withdrawn
- 2000-11-21 DE DE60014693T patent/DE60014693T2/de not_active Expired - Fee Related
- 2000-11-21 ES ES00980588T patent/ES2228636T3/es not_active Expired - Lifetime
- 2000-11-21 WO PCT/US2000/031895 patent/WO2001038293A1/en active IP Right Grant
- 2000-11-21 DK DK00980588T patent/DK1232141T3/da active
- 2000-11-21 PL PL355171A patent/PL202846B1/pl not_active IP Right Cessation
- 2000-11-21 MX MXPA02005174A patent/MXPA02005174A/es active IP Right Grant
- 2000-11-21 IL IL14953100A patent/IL149531A0/xx unknown
- 2000-11-21 HU HU0203594A patent/HUP0203594A2/hu unknown
- 2000-11-21 KR KR1020027006602A patent/KR100843991B1/ko not_active IP Right Cessation
- 2000-11-21 CN CNA2004100882450A patent/CN1636559A/zh active Pending
- 2000-11-21 NZ NZ519130A patent/NZ519130A/en unknown
- 2000-11-22 AR ARP000106165A patent/AR024498A1/es unknown
- 2000-11-23 TW TW089124917A patent/TWI268919B/zh not_active IP Right Cessation
-
2002
- 2002-05-08 IL IL149531A patent/IL149531A/en not_active IP Right Cessation
- 2002-05-23 NO NO20022446A patent/NO20022446L/no not_active Application Discontinuation
- 2002-06-20 ZA ZA200204986A patent/ZA200204986B/en unknown
- 2002-10-09 HK HK02107379A patent/HK1045835A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HK1045835A1 (en) | 2002-12-13 |
IL149531A0 (en) | 2002-11-10 |
EP1232141A1 (en) | 2002-08-21 |
PT1232141E (pt) | 2004-12-31 |
CZ20021816A3 (cs) | 2002-08-14 |
WO2001038293A1 (en) | 2001-05-31 |
TWI268919B (en) | 2006-12-21 |
AR024498A1 (es) | 2002-10-02 |
CN1399626A (zh) | 2003-02-26 |
KR100843991B1 (ko) | 2008-07-07 |
EP1232141B1 (en) | 2004-10-06 |
ATE278659T1 (de) | 2004-10-15 |
BR0015795A (pt) | 2002-07-23 |
AU1783301A (en) | 2001-06-04 |
NZ519130A (en) | 2003-09-26 |
ZA200204986B (en) | 2003-09-27 |
AU767835B2 (en) | 2003-11-27 |
PL202846B1 (pl) | 2009-07-31 |
DE60014693D1 (en) | 2004-11-11 |
ES2228636T3 (es) | 2005-04-16 |
CA2391288A1 (en) | 2001-05-31 |
NO20022446D0 (no) | 2002-05-23 |
PL355171A1 (en) | 2004-04-05 |
MXPA02005174A (es) | 2002-11-07 |
JP2003514889A (ja) | 2003-04-22 |
DE60014693T2 (de) | 2005-03-10 |
DK1232141T3 (da) | 2004-11-29 |
IL149531A (en) | 2008-12-29 |
SI1232141T1 (en) | 2004-12-31 |
HUP0203594A2 (en) | 2003-02-28 |
NO20022446L (no) | 2002-05-23 |
KR20030058931A (ko) | 2003-07-07 |
CN1636559A (zh) | 2005-07-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
CI01 | Publication of corrected invention patent application |
Correction item: Inventor Correct: Ullrich John William False: Missing third inventor Number: 9 Volume: 19 |
|
CI02 | Correction of invention patent application |
Correction item: Inventor Correct: Ullrich John William False: Missing third inventor Number: 9 Page: The title page Volume: 19 |
|
COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: MISS OF 3RD INVENTOR TO: ULLRICH JOHN WILLIAM |
|
ERR | Gazette correction |
Free format text: CORRECT: INVENTOR; FROM: MISS OF 3RD INVENTOR TO: ULLRICH JOHN WILLIAM |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20050427 Termination date: 20091221 |