CN1196474C - 脂质体包封的dna口服疫苗 - Google Patents

脂质体包封的dna口服疫苗 Download PDF

Info

Publication number
CN1196474C
CN1196474C CNB008134766A CN00813476A CN1196474C CN 1196474 C CN1196474 C CN 1196474C CN B008134766 A CNB008134766 A CN B008134766A CN 00813476 A CN00813476 A CN 00813476A CN 1196474 C CN1196474 C CN 1196474C
Authority
CN
China
Prior art keywords
liposome
liposomes
dna
group
micromolar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB008134766A
Other languages
English (en)
Chinese (zh)
Other versions
CN1376056A (zh
Inventor
G·格雷格里亚迪斯
Y·佩里尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lipoxen Technologies Ltd
Original Assignee
Lipoxen Technologies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lipoxen Technologies Ltd filed Critical Lipoxen Technologies Ltd
Publication of CN1376056A publication Critical patent/CN1376056A/zh
Application granted granted Critical
Publication of CN1196474C publication Critical patent/CN1196474C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CNB008134766A 1999-10-01 2000-10-02 脂质体包封的dna口服疫苗 Expired - Fee Related CN1196474C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99307786 1999-10-01
EP99307786.6 1999-10-01

Publications (2)

Publication Number Publication Date
CN1376056A CN1376056A (zh) 2002-10-23
CN1196474C true CN1196474C (zh) 2005-04-13

Family

ID=8241653

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB008134766A Expired - Fee Related CN1196474C (zh) 1999-10-01 2000-10-02 脂质体包封的dna口服疫苗

Country Status (11)

Country Link
US (1) US7008791B1 (https=)
EP (1) EP1217989B1 (https=)
JP (1) JP2003529550A (https=)
KR (1) KR100744237B1 (https=)
CN (1) CN1196474C (https=)
AT (1) ATE312599T1 (https=)
AU (1) AU7540500A (https=)
CA (1) CA2386024A1 (https=)
DE (1) DE60024843T2 (https=)
ES (1) ES2256043T3 (https=)
WO (1) WO2001024773A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2279127T3 (es) 2002-07-05 2007-08-16 Lipoxen Technologies Limited Procedimiento para aumentar una respuesta inmunitaria de vacunacion de acido nucleico.
EP1628636A1 (de) * 2003-05-09 2006-03-01 Novosom AG Injizierbare liposomale depots zum wirkstoffdelivery
JP4255396B2 (ja) * 2004-03-19 2009-04-15 津田駒工業株式会社 水噴射式織機の水受け装置
NZ578541A (en) * 2006-12-22 2012-04-27 Soluciones Biotecnologicas Innovacion Ltda Dna vaccines for fish
EP2146692A1 (en) * 2007-03-19 2010-01-27 Fresenius Kabi Oncology Limited Proliposomal and liposomal compositions
CN101940320B (zh) * 2010-08-06 2012-08-29 南昌大学 薄膜分散-动态高压微射流制备中链脂肪酸纳米脂质体
CN101940321B (zh) * 2010-08-06 2012-06-20 南昌大学 动态高压微射流-冻融法制备中链脂肪酸纳米脂质体
EP2708134A1 (en) 2012-09-17 2014-03-19 Unilever N.V. Dough compositions comprising a structured fat phase

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU728581B2 (en) 1996-09-13 2001-01-11 Lipoxen Limited Liposomes
FR2760193B1 (fr) * 1997-02-28 1999-05-28 Transgene Sa Lipides et complexes de lipides cationiques et de substances actives, notamment pour la transfection de cellules

Also Published As

Publication number Publication date
ATE312599T1 (de) 2005-12-15
WO2001024773A1 (en) 2001-04-12
JP2003529550A (ja) 2003-10-07
CA2386024A1 (en) 2001-04-12
US7008791B1 (en) 2006-03-07
KR20030011763A (ko) 2003-02-11
KR100744237B1 (ko) 2007-07-30
DE60024843T2 (de) 2006-08-10
EP1217989A1 (en) 2002-07-03
CN1376056A (zh) 2002-10-23
DE60024843D1 (de) 2006-01-19
AU7540500A (en) 2001-05-10
WO2001024773B1 (en) 2001-08-16
ES2256043T3 (es) 2006-07-16
EP1217989B1 (en) 2005-12-14

Similar Documents

Publication Publication Date Title
CN1138533C (zh) 脂质体
CN100340289C (zh) 增强核酸接种免疫应答的方法
Benvegnu et al. New generation of liposomes called archaeosomes based on natural or synthetic archaeal lipids as innovative formulations for drug delivery
CN1096851C (zh) 疫苗组合物佐剂
US20210322573A1 (en) Use of liposomes in a carrier comprising a continuous hydrophobic phase for delivery of polynucleotides in vivo
CA2192597A1 (fr) Utilisation d'un compose amphipathique cationique comme agent de transfection, comme adjuvant de vaccin, ou comme medicament
CN1085449A (zh) 疫苗或与其相关的改进
US20190275145A1 (en) Particulate vaccine formulations
JPH09501169A (ja) 小胞に生体高分子物質を高度に充填する方法
CN1196474C (zh) 脂质体包封的dna口服疫苗
CN1882358A (zh) 添加烷基磷脂酰胆碱作为辅药的疫苗组合物
US20200222322A1 (en) Phosphoserine containing compositions for immune tolerance induction
CN121311463A (zh) 可电离脂质化合物、包含其的脂质载体及应用
EP0713387B1 (en) A method for preparation of vesicles loaded with biological structures, biopolymers and/or oligomers
CN120158462A (zh) 编码水痘-带状疱疹病毒糖蛋白E的mRNA疫苗
EP1361862B1 (en) Liposome-mediated dna administration
CN1756534A (zh) 用于减少脂质体诱导的补体激活的脂质体组合物
WO2025224684A1 (en) Compositions and methods for producing engineered immune cells
CN1829535A (zh) 用于接种的sphingoid聚烷基胺缀合物

Legal Events

Date Code Title Description
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20050413

Termination date: 20111002