CN118829641A - 用于治疗脱发的化合物 - Google Patents

用于治疗脱发的化合物 Download PDF

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Publication number
CN118829641A
CN118829641A CN202280092697.2A CN202280092697A CN118829641A CN 118829641 A CN118829641 A CN 118829641A CN 202280092697 A CN202280092697 A CN 202280092697A CN 118829641 A CN118829641 A CN 118829641A
Authority
CN
China
Prior art keywords
compound
hair
compounds
hour
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202280092697.2A
Other languages
English (en)
Chinese (zh)
Inventor
丹尼尔·雷·孙
丹尼尔·沃尔特·吉尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pileji Pharmaceutical Co
Original Assignee
Pileji Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pileji Pharmaceutical Co filed Critical Pileji Pharmaceutical Co
Publication of CN118829641A publication Critical patent/CN118829641A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Birds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
CN202280092697.2A 2021-12-29 2022-12-21 用于治疗脱发的化合物 Pending CN118829641A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163294775P 2021-12-29 2021-12-29
US63/294,775 2021-12-29
PCT/US2022/082185 WO2023129854A1 (en) 2021-12-29 2022-12-21 Compounds for treatment of hair loss

Publications (1)

Publication Number Publication Date
CN118829641A true CN118829641A (zh) 2024-10-22

Family

ID=85157456

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202280092697.2A Pending CN118829641A (zh) 2021-12-29 2022-12-21 用于治疗脱发的化合物

Country Status (12)

Country Link
US (1) US20250163045A1 (enExample)
EP (1) EP4457226A1 (enExample)
JP (1) JP2025502850A (enExample)
KR (1) KR20240129011A (enExample)
CN (1) CN118829641A (enExample)
AR (1) AR128100A1 (enExample)
AU (1) AU2022425460A1 (enExample)
CA (1) CA3244825A1 (enExample)
IL (1) IL314007A (enExample)
MX (1) MX2024008333A (enExample)
TW (1) TW202333692A (enExample)
WO (1) WO2023129854A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12649736B2 (en) 2019-12-20 2026-06-09 The Regents Of The University Of California Synthesis of compounds to promote hair growth
EP4172159A4 (en) 2020-06-30 2024-01-10 The Regents of the University of California Compositions and methods for modulating hair growth
CN121005682A (zh) * 2024-05-24 2025-11-25 上海医药工业研究院有限公司 一种2-苯基-吡咯类化合物、其制备方法及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL321754A (en) 2017-06-30 2025-08-01 Univ California Compositions and methods for modulating hair growth
MX2021008089A (es) * 2019-01-02 2021-08-05 Univ California Composiciones y metodos para modular el crecimiento del cabello.
EP4172159A4 (en) * 2020-06-30 2024-01-10 The Regents of the University of California Compositions and methods for modulating hair growth
EP4172158A4 (en) * 2020-06-30 2024-01-10 The Regents of the University of California Compositions and methods for modulating hair growth

Also Published As

Publication number Publication date
CA3244825A1 (en) 2023-07-06
WO2023129854A1 (en) 2023-07-06
IL314007A (en) 2024-08-01
AR128100A1 (es) 2024-03-27
TW202333692A (zh) 2023-09-01
MX2024008333A (es) 2024-08-30
KR20240129011A (ko) 2024-08-27
EP4457226A1 (en) 2024-11-06
US20250163045A1 (en) 2025-05-22
AU2022425460A1 (en) 2024-07-18
JP2025502850A (ja) 2025-01-28

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