TW202333692A - 用於治療脫髮之化合物 - Google Patents

用於治療脫髮之化合物 Download PDF

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Publication number
TW202333692A
TW202333692A TW111149987A TW111149987A TW202333692A TW 202333692 A TW202333692 A TW 202333692A TW 111149987 A TW111149987 A TW 111149987A TW 111149987 A TW111149987 A TW 111149987A TW 202333692 A TW202333692 A TW 202333692A
Authority
TW
Taiwan
Prior art keywords
compound
hair growth
compounds
group
hour
Prior art date
Application number
TW111149987A
Other languages
English (en)
Chinese (zh)
Inventor
丹尼爾 雷 孫
丹尼爾 瓦特 基爾
Original Assignee
美商皮樂吉製藥公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 美商皮樂吉製藥公司 filed Critical 美商皮樂吉製藥公司
Publication of TW202333692A publication Critical patent/TW202333692A/zh

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Birds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
TW111149987A 2021-12-29 2022-12-26 用於治療脫髮之化合物 TW202333692A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163294775P 2021-12-29 2021-12-29
US63/294,775 2021-12-29

Publications (1)

Publication Number Publication Date
TW202333692A true TW202333692A (zh) 2023-09-01

Family

ID=85157456

Family Applications (1)

Application Number Title Priority Date Filing Date
TW111149987A TW202333692A (zh) 2021-12-29 2022-12-26 用於治療脫髮之化合物

Country Status (12)

Country Link
US (1) US20250163045A1 (enExample)
EP (1) EP4457226A1 (enExample)
JP (1) JP2025502850A (enExample)
KR (1) KR20240129011A (enExample)
CN (1) CN118829641A (enExample)
AR (1) AR128100A1 (enExample)
AU (1) AU2022425460A1 (enExample)
CA (1) CA3244825A1 (enExample)
IL (1) IL314007A (enExample)
MX (1) MX2024008333A (enExample)
TW (1) TW202333692A (enExample)
WO (1) WO2023129854A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12649736B2 (en) 2019-12-20 2026-06-09 The Regents Of The University Of California Synthesis of compounds to promote hair growth
EP4172159A4 (en) 2020-06-30 2024-01-10 The Regents of the University of California Compositions and methods for modulating hair growth
CN121005682A (zh) * 2024-05-24 2025-11-25 上海医药工业研究院有限公司 一种2-苯基-吡咯类化合物、其制备方法及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL321754A (en) 2017-06-30 2025-08-01 Univ California Compositions and methods for modulating hair growth
MX2021008089A (es) * 2019-01-02 2021-08-05 Univ California Composiciones y metodos para modular el crecimiento del cabello.
EP4172159A4 (en) * 2020-06-30 2024-01-10 The Regents of the University of California Compositions and methods for modulating hair growth
EP4172158A4 (en) * 2020-06-30 2024-01-10 The Regents of the University of California Compositions and methods for modulating hair growth

Also Published As

Publication number Publication date
CN118829641A (zh) 2024-10-22
CA3244825A1 (en) 2023-07-06
WO2023129854A1 (en) 2023-07-06
IL314007A (en) 2024-08-01
AR128100A1 (es) 2024-03-27
MX2024008333A (es) 2024-08-30
KR20240129011A (ko) 2024-08-27
EP4457226A1 (en) 2024-11-06
US20250163045A1 (en) 2025-05-22
AU2022425460A1 (en) 2024-07-18
JP2025502850A (ja) 2025-01-28

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