CN1184901C - Health-care Zaozhishen food - Google Patents

Abstract

The present invention provides Health-care Zaozhishen food which is characterized in that the Health-care Zaozhishen food is compounded from components of the following proportion by weight: 70 to 90 wt% of spirulina powder, 9 to 25 wt % of Huaqi ginseng, and 1 to 5 wt % of glossy ganoderma. After the spirulina powder, the Huaqi ginseng and the glossy ganoderma are mutually compounded, the advantages are improved, and the shortages are replenished; the present invention also has the advantages of no poison, no harm, high safety and reliability, and instant effect proved by various certifications; the SOD activity of organisms can be rapidly improved, and the MDA is lowered; the present invention simultaneously has the obvious functions of delaying aging, resisting radiation and regulating immunity and is new ideal health food.

Description

Health-care Zaozhishen food

The present invention relates to a kind of health food, relate in particular to a kind of can delaying senility, improve organism SOD (peroxidase, Sediment oxygen demand) vigor and reduce the health food of MDA (lipid peroxide, Methylene Dioxyampbetamine).

Spirulina (Spirulina) is a kind of ancient algae, through scientists study, it contains beta carotene, gamma-Linolenic acid, the strong liver factor, abundant chlorophyll, polysaccharide and the multiple compositions such as the factor that can promote the lactein generation, wherein beta carotene can change into vitamin A in vivo, and vitamin A can promote the fast breeding of new cell, strengthen the toughness of cell membrane, have important function to delaying senility.And gamma-Linolenic acid to be human body can't synthesize but be must obligato unrighted acid, it has the elimination free radical, promotes fat metabolism, reduce cholesterol level, prevent cholesterol solidifying in blood, it still is the precursor of prostaglandin, has radiation-resisting functional.The strong liver factor can promote liver cell regeneration, improves blood function.Chlorophyll can not only promote digestion, and in having and the toxin in the blood and it is got rid of external function, chlorophyll also has antiinflammation simultaneously, can strengthen the immunocompetence of human body.Polysaccharide can reduce the frequency of mutation that ionising radiation causes greatly, obviously improves the reparation synthesis capability of the DNA that endonuclease causes the excision repairing activity and the enhanced rad of damage dna.Can promote the factor that lactein produces, have the intestinal flora of recovery balance, gastric ulcer can be effectively eliminated in the effect of repairing the stomach mucous membrane. diseases such as constipation.In addition, spirulina can also promote the recovery of pancreatic functions.Therefore, it is comparatively desirable pure natural health-care.But obviously there is the slow deficiency that waits that takes effect in existing spirulina preparation, and just can take effect after need taking for a long time.

The object of the present invention is to provide a kind of instant effect, and need not to take for a long time, and the health-care Zaozhishen food that can delay senility.

Health food of the present invention is by following component in percentage by weight:

Spirulina 70-90%,

American ginseng 9-25%,

Glossy ganoderma 1-5%,

And an amount of starch, perhaps soybean oil, perhaps dextrin and sugar are made tablet, capsule or pulvis.

Wherein, spirulina (Spirulina) adopts the smart powder of blunt top spirulina.

American ginseng (American Ginseng) adopts the commercially available U.S. to produce the American ginseng powder.It has mends and not dry advantage.Concrete function is as follows: can reduce the infringement of radiation pair cell, improve memory and reaction sensitivity, antifatigue, the stress of alleviating, suppress tumour cell, irritate body and produce disease-resistant enzyme, reduce the situation of blood sugar, control insulin, strengthen body immunity, enhancing sexual function etc.

Glossy ganoderma (Ganoderma Lucidum (LeYss.ex Fr) Karst) is adopted commercially available high fine glossy ganoderma powder, and it can the beneficial motive, beneficial irritability, beneficial vital essence, it is refreshing to protect, go into the heart being responsible for production of blood, good color, and the cuisine canon body is not old for a long time, promotes longevity.In addition, glossy ganoderma has dual regulation to immune function of human body, can improve the ability of anti-chemical lesion of marrow and radiation injury, tumour cell there is the obvious suppression effect, can improves coronary circulation and myocardial blood supply, improve the body anoxia endurance, reduce blood fat, alleviate the atherosclerotic degree, promote the protein of normal structure and damaged tissue, nucleic acid to synthesize, stronger anti-aging effects is arranged.

Spirulina, American ginseng, behind the mutual compatibility of glossy ganoderma, the chapter of benefiting mutually of learning from other's strong points to offset one's weaknesses, and it is nontoxic, safe and reliable, through various testing identities, its instant effect, can improve the SOD vigor of organism rapidly and reduce MDA, have the function that significantly delays senility simultaneously, radiation-resisting functional and immunoloregulation function are the comparatively desirable health foods of a new generation.The present invention obtains proof by following test:

Table 1 Zaozhishen sheet is to the influence of drosophila survival test

Group	Sex	Dosage (%)	Sample number	Average weight (μ g)	The half death time (d)	The highest average life span (d)	Average life span (d)
								Control group	Male	0	215	625±40	46.59	63.7±3.34	46.43±9.79
Female	235	780±37	48.05	65.2±2.76	48.28±9.86
						Low	Male		0.03		228	620±27	49.20	62.0±4.27	47.56±11.18
Female	225	784±20	49.13	65.5±2.80	48.45±10.03
							In	Male		0.1	216	622±27	46.44	64.7±2.67	47.42±9.96
Female	233	772±40	54.73	71.0±1.89*	52.58±11.33*
						Inferior high		Male	0.3		236	624±26	48.50	68.2±2.57*	49.12±9.29*
Female	225	768±47	58.05	72.4±3.06*	56.59±9.72*
							High	Male		0.9	208	620±26	51.88	70.2±3.01*	51.59±8.92*
Female	230	788±18	52.23	68.5±3.84*	51.70±8.18*

* relatively there were significant differences (P＜0.05) with control group

The result shows that the average life span of male fruit bat 0.3%, 0.9% dosage group and the highest average life span are significantly higher than control group (P＜0.05), and the average life span of 0.1%, 0.3%, the 0.9% dosage group of female fruit bat and the highest average life span are significantly higher than control group (P＜0.05).

Table 2 respectively organize mouse initial body weight, mid-term body weight, finish body weight

Initial body weight body weight in mid-term finishes body weight

Group number of animals (only) body weight (g) number of animals (only) body weight (g) number of animals (only) body weight (g)

Control group 11 33.6 ± 6.9 11 34.0 ± 5.8 11 34.2 ± 5.6

Model group 11 34.6 ± 4.8 11 35.8 ± 3.8 11 35.5 ± 3.1

Low dose group 11 34.5 ± 5.7 11 33.6 ± 4.7 11 34.1 ± 5.6

Middle dosage group 11 35.6 ± 6.0 11 35.6 ± 5.2 11 37.8 ± 6.7

High dose group 11 34.5 ± 7.3 11 32.4 ± 4.2 11 36.0 ± 5.0

By table 2 as seen, each treated animal body weight before and after experiment does not have significant change.

Table 3 Zaozhishen sheet is to the influence of mice plasma lipid peroxide

Dosage group g/kg.bw number of animals (only) MDA nmol/ml P value

Control group 11 5.60 ± 0.89

Model group 11 6.80 ± 0.80＜0.01*

0.25 11 5.44±1.56 ＜0.05**

0.50 11 5.96±1.27

1.00 11 5.61±1.23

*: with the control group ratio; *: with the model group ratio.

Table 4 Zaozhishen sheet is to the influence of mice plasma SOD

Dosage group g/kg.bw number of animals (only) SOD vigor nU/ml P value

Control group 11 547 ± 126

Model group 11 329 ± 169＜0.01*

0.25 11 385±179

0.50 11 533±117 ＜0.01**

1.00 11 566±159 ＜0.01**

*: with the control group ratio; *: with the model group ratio.

The drosophila survival test of this inspection product, lipid peroxide and antioxidase result are all positive, and promptly photosynthetic board life oasis Zaozhishen sheet has function in delaying senility.

The photosynthetic board life of table 5 oasis Zaozhishen sheet is to the influence of mouse delayed allergy (DTH)

Group number of animals (only) swelling degree of the paw (mm) (the P value of X ± S)

Control group 13 0.19 ± 0.01

0.5g/kg.bw organize 11 0.39 ± 0.01*＜0.01

1.0g/kg.bw organize 13 0.37 ± 0.02*＜0.01

1.5g/kg.bw organize 13 0.34 ± 0.01**＜0.05

* compare with control group, highly significant difference (P＜0.01) is arranged; * compares with control group, and significant difference (P＜0.05) is arranged.

The photosynthetic board life of table 6 oasis Zaozhishen sheet is to the influence of mice serum hemolytic antibody product

Group number of animals (only) antibody product (the P value of X ± S)

Control group 13 187.23 ± 40.65

0.5g/kg.bw organize 11 171.82 ± 27.99＞0.05

1.0g/kg.bw organize 13 185.77 ± 27.86＞0.05

1.5g/kg.bw organize 12 180.75 ± 20.25＞0.05

The photosynthetic board life of table 7 oasis Zaozhishen sheet is engulfed the influence of chicken red blood cell ability to mouse macrophage

Group number of animals (only) phagocytic rate (the %) (phagocytic index of X ± S) (the P value of X ± S)

Contrast 12 33.42 ± 5.25 0.79 ± 0.08

0.5g/kg.bw organize 11 32.00 ± 3.52 0.89 ± 0.04*

1.0g/kg.bw organize 12 43.50 ± 5.14*, 1.39 ± 0.07*＜0.01

1.5g/kg.bw organize 12 44.33 ± 4.91*, 1.40 ± 0.06*＜0.01

* compare with control group, highly significant difference (P＜0.01) is arranged

The photosynthetic board life of table 8 oasis Zaozhishen sheet is to the influence of NK cells in mice activity

Group number of animals (only) NK cytoactive rate (%) (the P value of X ± S)

Contrast 12 30.39 ± 11.64

0.5g/kg.bw organize 11 33.54 ± 12.32＞0.05

1.0g/kg.bw organize 12 28.99 ± 10.88＞0.05

1.5g/kg.bw organize 12 40.84 ± 18.40＞0.05

0.5g/kg.bw, each dosage of 1.0g/kg.bw, 1.5g/kg.bw can improve tardy parasexuality respond of mouse and Turnover of Mouse Peritoneal Macrophages phagocytic function, has immunoregulation effect according to estimating according to (3.1.3 result's judgement) this product.

Table 9 Zaozhishen sheet is to the influence of total white blood cells

Group dosage number of animals leukocyte count

Mg/kg.bw (only) (* 10 ⁹/ L)

Blank 10 7.09 ± 2.01

Radiation contrasts 10 1.30 ± 0.39 ^*

Zaozhishen sheet 0.5 10 1.53 ± 0.48 ^{* ▲ ▲}

1.0 10 1.60±0.39 ^*▲▲

1.5 10 1.99±1.01 ^*▲▲

*: P＜0.05 (comparing) with the blank group, ^{▲ ▲}: P＜0.05 (comparing) with the radiation control group

Each dosage of this inspection product (photosynthetic board life oasis Zaozhishen sheet) can increase raying murine interleukin sum.

Table 10 Zaozhishen sheet is to the influence of raying mouse mean survival time

Group dosage number of animals mean survival time

Mg/kg.bw (only) (my god)

Blank 13 20.46 ± 5.28

Radiation contrasts 13 11.92 ± 6.69*

Zaozhishen sheet 0.5 13 10.62 ± 4.09*

1.0 14 15.78±5.39

1.5 13 15.61±6.37

*: P＜0.05 (comparing) with the blank group

Annotate: the time-to-live is the 1st fate behind the irradiation in the table, the dead animals survived time in radiation after 23 days.

Mean survival time of this inspection product 1.0g/kg.bw and 1.5/kg.bw dosage group mouse and blank group be there was no significant difference relatively.The mean survival time that can keep the raying mouse is at normal level.

Table 11 Zaozhishen sheet to mouse irradiation after the influence of 18 days survival rates

Group dosage is observed several 18 days survival rates of number of animals surviving animals

(mg/kg.bw) (only) (only) (%)

Blank 13 11 84.62

Radiation contrasts 13 4 30.79*

Zaozhishen sheet 0.5 13 1 7.69*

1.0 14 8 57.14

1.5 13 7 53.85

*: P＜0.005 (comparing) with the blank group

18 days survival rates and blank group there was no significant difference relatively behind this inspection product 1.0g/kg.bw and the 1.5g/kg.bw dosage group mouse irradiation, the survival rate that can keep the raying mouse is at normal level.

Table 12 Zaozhishen sheet is to the influence of mouse Bone marrow cells micronucleus rate

Group dosage number of animals is had a liking for many red blood cell number micronucleus and is counted micronuclear rates

(g/kg.bw) (only) (individual/only) (individual) (‰)

Blank 10 1,000 0.60 ± 0.52 0.60

Radiation contrasts 10 1,000 14.90 ± 1.29* 14.90

Zaozhishen sheet 0.5 10 1,000 9.10 ± 1.37** 9.10

1.0 10 1000 4.40±1.27** 4.40

1.5 10 1000 2.70±1.16** 2.70

*: P＜0.01 (comparing), * *: P＜0.01 (comparing) with the radiation control group with the blank group

Three dosage groups of this inspection product (photosynthetic board life oasis Zaozhishen sheet) all have the effect of remarkable reduction raying PCEMNR micronucleus occurrence rate, and dose-response relationship is preferably arranged.

This inspection product (photosynthetic board life oasis Zaozhishen sheet) can make raying murine interleukin number increase, and marrow polychromatic erythrocyte micronuclear rates reduces, and keeps its mean survival time and 18 days survival rates at normal level.Has certain radiation resistance.

Embodiment 1

Get spirulina powder 700g, American ginseng powder 250g, glossy ganoderma powder 50g, food starch 10g mixes the back and makes 2000 tablets of Zaozhishen tablets with existing processing method, and obey 2-3 every day, obeys 2 at every turn.

Embodiment 2

Get spirulina powder 900g, American ginseng powder 90g, glossy ganoderma powder 10g, edible soybean oil 150g, ethyl cellulose 20g makes 1000 soft capsules with existing processing method behind the emulsification mixing, and obey 2-3 every day, obeys 1 at every turn.

Embodiment 3

Get spirulina powder 800g, American ginseng powder 170g, glossy ganoderma powder 30g, sucrose 1300g, dextrin 700g, ethanol is an amount of, mixes the back and makes 1000 bagged soluble granules with existing processing method, and obey 2-3 every day, obeys 1 bag at every turn, and brew with boiling water.

Claims (1)

1, a kind of health-care Zaozhishen food is characterized in that it is by following component in percentage by weight:

Spirulina 70-90%,

American ginseng 9-25%,

Glossy ganoderma 1-5%, and an amount of starch, perhaps soybean oil, perhaps dextrin and sugar are made tablet, capsule or pulvis.