CN100409855C - Tablet containing lucid ganoderma and spirulina spp. ,and its preparation method - Google Patents

Abstract

The present invention relates to a tablet of ganoderma lucidum and spirulina and a preparation method thereof. 87 to 92.5% of spirulina fine powder and 5 to 8% of ganoderma lucidum spore powder with broken walls are used as principal raw material, and 1.0 to 2.0% of cellulose, 1.25 to 2.5% of silicon dioxide and 0.25 to 0.5% of magnesium stearate are matched. After the material is sufficiently mixed and sieved by a sieve of 60 meshes, dry powder is directly pressed into the tablet by a ZP19 rotary tablet machine with a molding method. The product of the present invention not only maintains spirulina nutrients, but also supplements the biological active components of the ganoderma lucidum spore powder with broken walls. The product is rich in more than 55% of rich good protein, eight requisite amino acids for human bodies, various vitamins, gamma-linolenic acids, beta-carotenes whose quantity is 10 times of that of carrots, nutrient components(polysaccharide, etc.) and biological active components. The tablet can supplement and balance nutrients, and obviously enhance body immunity. The tablet is an ideal nutrient health-care food for people with cancer and people who have weak bodies.

Description

Lucid ganoderma spirulina tablet agent and preparation method thereof

Technical field

The present invention relates to a kind ofly to be used for enhance immunity, suppress tumor, life lengthening, antidotal nutrient and healthcare products, particularly a kind of lucid ganoderma spirulina tablet agent the invention still further relates to the preparation method of this complex tablet.

Background technology

Diet and nutrition are the major issues that is related to people's health and thousands upon thousands family daily lifes.According to national nutrition survey and the Ministry of Public Health statistics to disease, China resident is existing dull or lack the Deficiency disease that is caused because of food variety, as iron deficiency anemia, rickets, child's zinc deficiency and vitamin A B deficiency disease etc.; Have again because meals are uneven formed and some nutritional disorder's diseases associated, as cardiovascular disease, cerebrovascular disease, malignant tumor etc.; No matter be child or adult, cause the extraordinary or fat real nutrition problem that has also become China area that are fairly developed economically of body weight owing to surfeit.Cancer is very big to the threat of human health and life simultaneously, and it and cardiovascular disease have become two big difficulties medically.Constitute two of the cause of death in the whole world.In the whole world 5,200,000,000 populations, the new cancer stricken of 7,000,000 people there is approximately every year, has every year more than 500 ten thousand people to die from cancer approximately, cancer patient's death is just arranged almost per 6 seconds.China on average has the new cancer stricken of 1,500,000 people present every year approximately, there are every year 800000 people to die from cancer approximately, dead 1949 of cancer account for the tenth of total cause of death, wherein pulmonary carcinoma, cancer of pancreas, hepatocarcinoma, nasopharyngeal carcinoma, carcinoma of prostate, malignant lymphoma etc., the trend that rising is arranged in recent years, because popularizing of anti-cancer measure, cervical cancer, testis cancer, leukemia etc. have a declining tendency.

At present, very popular to the research and development of rare Chinese medicines such as Ganoderma, product is also many especially.See that from dosage form the overwhelming majority is oral liquid, wine, capsule; Adopt crude drug in whole on the raw material, join material and aspect fortification, be short of, long-time edible, easily get angry; The adjuvant ratio is big, generally accounts for more than the 15-20%; The technological operation complexity.

Summary of the invention

The object of the present invention is to provide a kind ofly can replenish, balanced nutrients, significantly enhancing human body immunity power; The opposing radiation suppresses the growth of tumor cell, alleviates the damage of cancer patient radiotherapy chemotherapy, life lengthening, antidotal a kind of lucid ganoderma spirulina tablet agent, and its technological operation is simple, steady quality.

The objective of the invention is to be achieved through the following technical solutions:

A kind of lucid ganoderma spirulina tablet agent is prepared from by following raw material and proportioning:

Spirulina powder 87-92.5% Sporoderm-broken Ganoderma Lucidum Spore powder 5-8% silica 1 .25-2.5%

Cellulose 1.0-2.0% magnesium stearate 0.25-0.5%;

Its preparation method is:

Spirulina powder, Sporoderm-broken Ganoderma Lucidum Spore powder were mixed 60 mesh sieves, be equipped with silicon dioxide, cellulose, magnesium stearate again, respectively behind pulverizing, abundant mix homogeneously, cross the 40-60 eye mesh screen, adopt rotary tablet machine, pressure is 40,000 Ns, thick 3 millimeters of sheet, and dry powder straight forming method is pressed into tablet.

Ganoderma just is listed in top gradely in the Shennong's Herbal of the Eastern Han Dynasty before bimillennium, think " food for a long time, it is not old to make light of one's life by commiting suicide, the angle prolongs life ".Put down in writing in the Compendium of Material Medica that Ming Dynasty's Li Shizhen (1518-1593 A.D.) is write: Ganoderma bitter in the mouth, flat, nontoxic, the beneficial motive is invigorated blood circulation, and goes into heart hyperemia, helps the heart to fill arteries and veins, calm the nerves, lung benefiting gas, tonifying liver gas, invigorating middle warmer increases wisdom, good color, sharp joint, hard muscles and bones is eliminated the phlegm, and is good for the stomach.Ganoderma belongs to dish portion in Compendium of Material Medica, the flat nontoxic food of a specified duration of property is not harmful to the health, and is the medicine of going up very much, conforms with very much the intension of Chinese's integration of edible and medicinal herbs.

Modern medicine proves: Ganoderma contains several physiological active substances, can regulate, strengthen body immunity, and neurasthenia, rheumatic arthritis, coronary heart disease, hypertension, hepatitis, diabetes, tumor etc. are had good synergistic therapeutic action.In addition, Ganoderma also has effects such as resisting fatigue, looks improving and the skin nourishing, slow down aging.

The Ganoderma spore powder of one of primary raw material of the present invention is that the Ganoderma development later stage launches the seed that discharges, biologically claim " basidiospore ", be powder after putting together, the common name Ganoderma spore powder, its utilization and research are newfound in recent years, Ganoderma spore powder is collected very difficulty under natural environment, approximately produce 1000 kilograms of former Ganoderma Lucidums and could collect 1 kilogram of spore powder, each spore diameter has only the 5-8 micron, spore contains the polysaccharide peptide abundanter than Ganoderma, ribosidoadenine, protein, enzyme, special composition such as selenium element, Ganoderma spore powder is in enhance immunity, and the drug effect aspect that suppresses tumor is considerably beyond its parent Ganoderma.

Ganoderma spore powder is rich in polysaccharide peptide, triterpenes Ganodenic acid, natural organic germanium, enzyme, selenium element isoreactivity material, experimental results show that through domestic and international pharmacological research:

Peptidoglycan: kill 90% above cancerous cell effectively, improve the content of immunoglobulin and complement rapidly, directly stimulate the ability of synthetic interleukin I of lymphocyte and II, stimulate tumor necrosis factor to produce, the activating macrophage phagocytic function, strengthen NK (NKT) cell activity, strengthen body immunity.

Ganoderan: but the strengthening immune system function, prophylaxis of tumours and cancer; Bring high blood pressure down the generation of angiocardiopathy preventing; Stimulate secretion of insulin, blood sugar lowering concentration.

The Ganodenic acid of triterpenes: can directly kill tumor cell; Improve allergic constitution, the dephlogistication symptom; Cholesterol reducing is avoided sclerosis of blood vessels; Strengthen liver function, perfect Alimentary running.

Natural organic germanium: the ability that can strengthen the blood of human body oxygen uptake reaches more than 1.5 times, enhances metabolism, and eliminates interior free yl, prevents cell senescence; Can from cancerous cell, press power taking, its current potential is descended, thereby anticancer worsens, and prevent to other organ place diffusion; Natural organic germanium anticancer diffusibility reaches 89.3%.

Ribosidoadenine: suppress platelet aggregation, prevent thrombosis.

Trace element-selenium: prophylaxis of cancer, ease the pain, the prevention prostatic lesion, with vitamin C and usefulness, but prevention of cardiac strengthens sexual function.

Another primary raw material spirulina (Spirulina) of the present invention is a class rudimentary plant, genus Cyanophyta (cyomophyta) Oscillariaceae (Oscilatoriaceae), they are the same with antibacterial, there is not real nucleus (title protokaryon) in the cell, so claim cyanobacteria again.The cellularity of cyanophyceae is original, and very simple, is the photosynthetic organism that occurs the earliest on the earth, has had 3,500,000,000 years on this celestial body.Prove after deliberation; it contains 8 seed amino acids that 60-70% protein contains needed by human, multivitamin, tens kinds of trace element and mineral; contain phycocyanin beta-carotene, gamma-Linolenic acid and polysaccharides multiple bioactive substances such as (0.5-1.5%); the low-sugar low-fat fat; having effects such as the body immunity of enhancing, blood fat reducing, blood sugar lowering, antitumor, now is national Chinese medicine protection kind.Be international biology, a kind of medicine food dual purpose plant albumen new resources of threpsology and medical circle extensive concern.

The present invention shows that through Gansu Prov. Medical Science Research Inst.'s { sweet (province) medical courses in general are defended searching the (2005) No. 0507 } physics and chemistry and sanitary inspection report this product contains protein 57%, total flavones 12.5mg/kg, and health and heavy metal content index meet relevant criterion.

Test basis:

GB/T 5009.3.5.11.12.17---2003, health food check and assessment technique standard

GB/T 4789.23.4.5.10.11.15---2003

Assay: GB/T5009---2003, GB/T4789---2003 subordinate list

Inspection item	Unit	Detected value
			Plumbous	mg/kg	0.03
Arsenic	mg/kg	Do not detect
			Hydrargyrum	mg/kg	Do not detect
Moisture content	％	5.3
			Protein	％	58.33
Total polysaccharides	mg/kg	11.35
			Total plate count	CFU/g	130

Coliform	MPN/100g	＜30
			Salmonella		Do not detect
Shigella		Do not detect
			Staphylococcus aureus		Do not detect
Hemolytic streptococcus		Do not detect
			Mycete	CFU/g	＜10
Yeast	CFU/g	＜10

The present invention is guidance with the theory of Chinese medical science, in conjunction with the modern medicine principle, forms scientific formula with spirulina powder, Sporoderm-broken Ganoderma Lucidum Spore powder raw material.Be characterized in:

(1) prescription is unique, with the spirulina powder is basic nutrient source, provide and enriched high quality protein, aminoacid, and multivitamin, tens kinds of trace element and mineral, beta-carotene, gamma-Linolenic acid and polysaccharides multiple bioactive substances such as (0.5-1.5%).Science compatibility Cordyceps, Fructus Lycii, green tea extract, each functional component are collaborative mutually, have strengthened immunomodulating, antitumor and hepatoprotective effect.Reinforce insufficiency and reduce excessiveness, blood circulation promoting and blood stasis dispelling, supplementing QI for promoting the production of body fluid; Microcirculation improvement plays two-ways regulation blood glucose, effect of prevent diabetes complication and heart and brain pipe disease.

(2) raw material is a pure natural medicine food dual purpose plant extract, and consumption is fewer but better, and effect is outstanding.

(3) the interpolation adjuvant is few, is guaranteeing content of effective below 5%.

(4) technology is simple, constant product quality.Press the main ingredient compatibility on technology, dry powder direct tabletting is promptly plastic.

(5) comprehensive nutrition, effect is obvious.This product has not only kept nutritious spirulina but also augmented bioactive ingredients in the Sporoderm-broken Ganoderma Lucidum Spore powder, be rich in eight seed amino acids that enrich high quality protein and needed by human more than 55%, nutritional labeling and bioactive substances such as multivitamin, gamma-Linolenic acid, beta-carotene (be Radix Dauci Sativae 10 times), polysaccharide material, can replenish balanced nutrients, significantly enhancing human body immunity power; The opposing radiation suppresses the growth of tumor cell, alleviates the damage of cancer patient radiotherapy chemotherapy; Life lengthening, defying age.

The specific embodiment

Below in conjunction with embodiment the present invention is further elaborated:

Embodiment 1

Get smart powder 870 grams of spirulina (Spirlina), Sporoderm-broken Ganoderma Lucidum Spore powder 80 grams of sporoderm-broken rate more than 90% mixed 60 mesh sieves for primary raw material, were equipped with cellulose 20 grams again, silicon dioxide 25 grams, magnesium stearate 5 grams fully behind the mix homogeneously, are crossed 60 eye mesh screens, adopt the ZP19 rotary tablet machine, pressure is 40,000 Ns, thick 3 millimeters of sheet, and dry powder straight forming method is pressed into tablet.Making weight is 0.3 gram/sheet composite sheet, and every contains effect raw material 0.280 gram, adjuvant 0.02 gram.

Embodiment 2

Get smart powder 925 grams of spirulina (Spirlina), Ganoderma extract 50 grams of sporoderm-broken rate more than 90% mixed 60 mesh sieves for primary raw material, were equipped with cellulose 10 grams again, silica 1 2.5 grams, magnesium stearate 2.5 grams fully behind the mix homogeneously, are crossed 40 eye mesh screens, adopt the ZP19 rotary tablet machine, pressure is 40,000 Ns, thick 3 millimeters of sheet, and dry powder straight forming method is pressed into tablet.Make the composite sheet that weight is 0.3 gram/sheet, every contains effect raw material 0.29 gram, adjuvant 0.01 gram.

Claims (3)

1. lucid ganoderma spirulina tablet agent is characterized in that being prepared from by following raw material and proportioning:

Spirulina powder 87-92.5% Sporoderm-broken Ganoderma Lucidum Spore powder 5-8% silica 1 .25-2.5%

Cellulose 1.0-2.0% magnesium stearate 0.25-0.5%

2. method for preparing lucid ganoderma spirulina tablet agent as claimed in claim 1, it is characterized in that according to following process preparation: spirulina, Sporoderm-broken Ganoderma Lucidum Spore powder are mixed sieve, be equipped with silicon dioxide again, magnesium stearate, respectively behind pulverizing, abundant mix homogeneously, cross the 40-60 eye mesh screen, adopt rotary tablet machine, the compacting of dry powder straight forming method forms.

3. a kind of method for preparing the lucid ganoderma spirulina tablet agent according to claim 2, the pressure that it is characterized in that described employing rotary tablet machine are 35～40,000 Ns, thick 3 millimeters of sheet.