CN118460487A - 生产omega-羟基化的脂肪酸衍生物的方法 - Google Patents
生产omega-羟基化的脂肪酸衍生物的方法 Download PDFInfo
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- CN118460487A CN118460487A CN202410503321.7A CN202410503321A CN118460487A CN 118460487 A CN118460487 A CN 118460487A CN 202410503321 A CN202410503321 A CN 202410503321A CN 118460487 A CN118460487 A CN 118460487A
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- fatty acid
- hydroxy fatty
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- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0077—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
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- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
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- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
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- C12P7/00—Preparation of oxygen-containing organic compounds
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- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
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- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
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- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/14—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen (1.14.14)
- C12Y114/14001—Unspecific monooxygenase (1.14.14.1)
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- C12Y114/15—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen (1.14.15)
- C12Y114/15003—Alkane 1-monooxygenase (1.14.15.3)
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- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/0102—Diacylglycerol O-acyltransferase (2.3.1.20)
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- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/01075—Long-chain-alcohol O-fatty-acyltransferase (2.3.1.75)
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- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/01—Carboxylic ester hydrolases (3.1.1)
- C12Y301/01005—Lysophospholipase (3.1.1.5)
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- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/02—Thioester hydrolases (3.1.2)
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- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/02—Thioester hydrolases (3.1.2)
- C12Y301/02014—Oleoyl-[acyl-carrier-protein] hydrolase (3.1.2.14), i.e. ACP-thioesterase
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- C07K2319/00—Fusion polypeptide
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- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
- C12Y102/01042—Hexadecanal dehydrogenase (acylating) (1.2.1.42), i.e. fatty acyl-CoA reductase
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361835464P | 2013-06-14 | 2013-06-14 | |
| US61/835,464 | 2013-06-14 | ||
| PCT/US2014/042594 WO2014201474A1 (en) | 2013-06-14 | 2014-06-16 | Methods of producing omega-hydroxylated fatty acid derivatives |
| CN201480033702.8A CN105378486B (zh) | 2013-06-14 | 2014-06-16 | 生产omega-羟基化的脂肪酸衍生物的方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201480033702.8A Division CN105378486B (zh) | 2013-06-14 | 2014-06-16 | 生产omega-羟基化的脂肪酸衍生物的方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN118460487A true CN118460487A (zh) | 2024-08-09 |
Family
ID=51177165
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202410503321.7A Pending CN118460487A (zh) | 2013-06-14 | 2014-06-16 | 生产omega-羟基化的脂肪酸衍生物的方法 |
| CN201480033702.8A Active CN105378486B (zh) | 2013-06-14 | 2014-06-16 | 生产omega-羟基化的脂肪酸衍生物的方法 |
| CN202410501856.0A Pending CN118374462A (zh) | 2013-06-14 | 2014-06-16 | 生产omega-羟基化的脂肪酸衍生物的方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201480033702.8A Active CN105378486B (zh) | 2013-06-14 | 2014-06-16 | 生产omega-羟基化的脂肪酸衍生物的方法 |
| CN202410501856.0A Pending CN118374462A (zh) | 2013-06-14 | 2014-06-16 | 生产omega-羟基化的脂肪酸衍生物的方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US10711288B2 (https=) |
| EP (2) | EP2984490B1 (https=) |
| JP (3) | JP7004500B2 (https=) |
| KR (4) | KR20220053681A (https=) |
| CN (3) | CN118460487A (https=) |
| AU (2) | AU2014277874B2 (https=) |
| BR (2) | BR112015031233A2 (https=) |
| CA (1) | CA2915229A1 (https=) |
| MX (2) | MX385154B (https=) |
| MY (3) | MY203897A (https=) |
| SI (1) | SI2984490T1 (https=) |
| WO (1) | WO2014201474A1 (https=) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2984490T1 (sl) | 2013-06-14 | 2020-10-30 | Genomatica, Inc. | Metode proizvodnje derivatov omega hidroksilirane maščobne kisline |
| EP3129492B1 (en) * | 2014-04-10 | 2020-06-03 | Genomatica, Inc. | Chemo-enzymatic process for the preparation of lactones and macrocyclic ketones |
| WO2015176020A1 (en) | 2014-05-16 | 2015-11-19 | Provivi, Inc. | Synthesis of olefinic alcohols via enzymatic terminal hydroxylation |
| CN106604990B (zh) * | 2014-06-16 | 2022-04-05 | 基因组股份公司 | 具有改进的特性的ω-羟化酶相关的融合多肽 |
| EP4089176A1 (en) | 2014-07-18 | 2022-11-16 | Genomatica, Inc. | Microbial production of 1,3 diols |
| US11319562B2 (en) | 2015-04-15 | 2022-05-03 | Ramon Gonzalez | Modified fatty acid biosynthesis with ACP-dependent thiolases |
| WO2016168247A1 (en) * | 2015-04-15 | 2016-10-20 | William Marsh Rice University | Modified fatty acid biosynthesis with acp-dependent thiolases |
| EP3378940B1 (en) * | 2015-10-27 | 2020-06-03 | Korea Research Institute of Bioscience and Biotechnology | Method for producing heavy chain diol |
| KR101903553B1 (ko) * | 2015-10-27 | 2018-10-04 | 한국생명공학연구원 | 중쇄 아미노카르복시산의 생산 방법 |
| WO2017101987A1 (en) * | 2015-12-15 | 2017-06-22 | REG Life Sciences, LLC | Omega-hydroxylase-related fusion polypeptide variants with improved properties |
| CN107201356A (zh) * | 2016-03-17 | 2017-09-26 | 中国科学院青岛生物能源与过程研究所 | 支撑p450脂肪酸脱羧酶活性的还原伴侣蛋白组合及其应用 |
| MY205555A (en) | 2017-04-03 | 2024-10-25 | Genomatica Inc | Thioesterase variants having improved activity for the production of medium-chain fatty acid derivatives |
| KR102170282B1 (ko) * | 2017-12-15 | 2020-10-29 | 건국대학교 산학협력단 | α,ω-디올류 생산하는 재조합 미생물 및 α,ω-디올류의 생산방법 |
| TWI701040B (zh) * | 2018-03-19 | 2020-08-11 | 國立臺灣大學 | 蛋白質的用途及包含該蛋白質之全細胞催化系統及其應用 |
| EP3792351A4 (en) | 2018-04-16 | 2022-01-19 | Korea Research Institute of Bioscience and Biotechnology | Method for producing multi-hydroxy derivatives of polyunsaturated fatty acids |
| EP3824071A4 (en) * | 2018-07-17 | 2022-04-20 | Conagen Inc. | BIOSYNTHETIC MANUFACTURE OF GAMMA LACTONES |
| KR102117828B1 (ko) | 2018-07-19 | 2020-06-02 | 서울대학교산학협력단 | 레귤론 변이를 통한 지방산 및 지방산 유도체 생산에서 불포화도 감소 |
| EP3844179A4 (en) | 2018-08-31 | 2022-08-31 | Genomatica, Inc. | XYLR MUTANT FOR IMPROVED XYLOSE UTILIZATION OR IMPROVED CO-UTILIZATION OF GLUCOSE AND XYLOSE |
| CN111218485B (zh) * | 2018-11-26 | 2023-01-24 | 中国科学院大连化学物理研究所 | 一种生产ω-1-羟基脂肪酸的方法 |
| CN111218430B (zh) * | 2018-11-26 | 2022-06-14 | 中国科学院大连化学物理研究所 | 一种nadh类似物依赖型的细胞色素p450还原酶及其应用 |
| CN111592996A (zh) * | 2019-12-09 | 2020-08-28 | 福建省水产研究所(福建水产病害防治中心) | 一种芽孢杆菌cqn-2高密度发酵培养方法 |
| EP4314274A4 (en) * | 2021-03-29 | 2026-01-07 | Genomatica Inc | PRODUCTION OF NON-NATIVE MONOUNSATURATED FATTY ACIDS IN BACTERIA |
| JP2023005283A (ja) * | 2021-06-28 | 2023-01-18 | 出光興産株式会社 | ペプチドタグ付加タンパク質を用いた代謝物生産 |
| US20250207159A1 (en) | 2022-03-16 | 2025-06-26 | Genomatica, Inc. | Microorganisms And Methods For Production Of Fatty Acid Derivatives With Reduced Levels Of Byproducts |
| CN114480513A (zh) * | 2022-04-01 | 2022-05-13 | 北京林业大学 | 一种基因编辑酵母体外合成麝香酮的方法 |
| CN115537369B (zh) * | 2022-11-09 | 2024-03-01 | 云南农业大学 | 2-十二烯二酸促进蒙氏假单胞菌生长和定殖的应用 |
| CN116064362B (zh) * | 2022-12-15 | 2025-10-28 | 浙江大学 | 一种利用葡萄糖从头合成12-氨基月桂酸的基因工程菌及其构建和应用 |
| CN116790529B (zh) * | 2023-05-24 | 2025-01-17 | 天津大学 | P450 bm3蛋白突变体及其应用 |
| CN117343970B (zh) * | 2023-10-24 | 2025-01-21 | 杭州佳嘉乐生物技术有限公司 | 一种提升植物油脂亲肤感的油脂发酵方法 |
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