CN118453592A - 用于治疗糖尿病的葡萄糖激酶活化剂组合物 - Google Patents
用于治疗糖尿病的葡萄糖激酶活化剂组合物 Download PDFInfo
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- CN118453592A CN118453592A CN202410499223.0A CN202410499223A CN118453592A CN 118453592 A CN118453592 A CN 118453592A CN 202410499223 A CN202410499223 A CN 202410499223A CN 118453592 A CN118453592 A CN 118453592A
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- diabetes
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- glucokinase activator
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- Vascular Medicine (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US201261648110P | 2012-05-17 | 2012-05-17 | |
| US61/648,110 | 2012-05-17 | ||
| CN201380024802.XA CN104349790A (zh) | 2012-05-17 | 2013-05-15 | 用于治疗糖尿病的葡萄糖激酶活化剂组合物 |
| PCT/US2013/041076 WO2013173417A2 (en) | 2012-05-17 | 2013-05-15 | Glucokinase activator compositions for the treatment of diabetes |
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| CN201380024802.XA Pending CN104349790A (zh) | 2012-05-17 | 2013-05-15 | 用于治疗糖尿病的葡萄糖激酶活化剂组合物 |
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| KR101878252B1 (ko) | 2010-05-26 | 2018-07-13 | 브이티브이 테라퓨틱스 엘엘씨 | 글루코키나아제 활성화제와 병용되는 메트포르민의 용도, 및 메트포르민과 글루코키나아제 활성화제를 포함하는 조성물 |
| CN118453592A (zh) * | 2012-05-17 | 2024-08-09 | Vtv治疗有限责任公司 | 用于治疗糖尿病的葡萄糖激酶活化剂组合物 |
| KR102408480B1 (ko) | 2018-05-30 | 2022-06-10 | 이삼구 | 당뇨질환의 치료용 조성물 |
| CN114209694A (zh) * | 2018-05-31 | 2022-03-22 | 华领医药技术（上海）有限公司 | 含有葡萄糖激酶激活剂和ppar受体激活剂的药物组合及其制备方法和用途 |
| WO2019241089A1 (en) | 2018-06-12 | 2019-12-19 | Vtv Therapeutics Llc | Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs |
| US11872221B2 (en) | 2020-01-31 | 2024-01-16 | Hua Medicine (Shanghai) Ltd. | Treating untreated or treatment-resistant diabetes with glucokinase activator |
| CA3169432A1 (en) * | 2020-01-31 | 2021-08-05 | Hua Medicine (Shanghai) Ltd. | Treating treatment-resistant diabetes with glucokinase activator |
| WO2021167840A1 (en) | 2020-02-18 | 2021-08-26 | Vtv Therapeutics Llc | Sulfoxide and sulfone glucokinase activators and methods of use thereof |
| US11857536B2 (en) | 2020-06-04 | 2024-01-02 | Hua Medicine (Shanghai) Ltd. | Glucokinase activator for treating diabetes with renal impairment |
| CA3185834A1 (en) * | 2020-06-04 | 2021-12-09 | Hua Medicine (Shanghai) Ltd. | Glucokinase activator for treating diabetes with hepatic impairment |
| AU2020451588A1 (en) * | 2020-06-04 | 2023-01-19 | Hua Medicine (Shanghai) Ltd. | Glucokinase activator for treating diabetes with renal impairment |
| CA3181722A1 (en) * | 2020-06-08 | 2021-12-16 | Jing TENG | Salts or co-crystals of {2-[3-cyclohexyl-3-(trans-4-propoxy-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid and uses thereof |
| AU2021289591A1 (en) * | 2020-06-08 | 2023-01-19 | Vtv Therapeutics Llc | Crystalline forms of {2-[3-cyclohexyl-3-(trans-4-propoxy- cyclohexyl)-ureido]-thiazol-5-ylsulfanyl} -acetic acid and and uses thereof |
| CN115350268B (zh) * | 2022-08-24 | 2025-02-11 | 深圳青澜生物技术有限公司 | 一种用于治疗糖尿病的制剂、微针及其制备工艺 |
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| US6294546B1 (en) * | 1999-08-30 | 2001-09-25 | The Broad Of Trustees Of The Leland Stanford Junior University | Uses of diterpenoid triepoxides as an anti-proliferative agent |
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| KR101878252B1 (ko) * | 2010-05-26 | 2018-07-13 | 브이티브이 테라퓨틱스 엘엘씨 | 글루코키나아제 활성화제와 병용되는 메트포르민의 용도, 및 메트포르민과 글루코키나아제 활성화제를 포함하는 조성물 |
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2013
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- 2013-05-15 WO PCT/US2013/041076 patent/WO2013173417A2/en not_active Ceased
- 2013-05-15 HK HK15103235.2A patent/HK1202458A1/xx unknown
- 2013-05-15 AU AU2013262895A patent/AU2013262895A1/en not_active Abandoned
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- 2013-05-15 CN CN201380024802.XA patent/CN104349790A/zh active Pending
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| HK1202458A1 (en) | 2015-10-02 |
| KR20150013838A (ko) | 2015-02-05 |
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| US10980861B2 (en) | 2021-04-20 |
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| US10588943B2 (en) | 2020-03-17 |
| AU2013262895A1 (en) | 2014-11-13 |
| CA2872021C (en) | 2022-08-16 |
| JP6234443B2 (ja) | 2017-11-22 |
| KR20210027547A (ko) | 2021-03-10 |
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| US20180311314A1 (en) | 2018-11-01 |
| IN2014DN09554A (enExample) | 2015-07-17 |
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| CA2872021A1 (en) | 2013-11-21 |
| WO2013173417A2 (en) | 2013-11-21 |
| AU2017203835B2 (en) | 2018-11-22 |
| US10004782B2 (en) | 2018-06-26 |
| KR102371364B1 (ko) | 2022-03-07 |
| SG10201609644UA (en) | 2017-01-27 |
| SG11201406987UA (en) | 2014-12-30 |
| MX360304B (es) | 2018-10-29 |
| WO2013173417A3 (en) | 2014-02-20 |
| EP2849776A2 (en) | 2015-03-25 |
| AU2017203835A1 (en) | 2017-06-22 |
| BR112014028622A2 (pt) | 2017-06-27 |
| EA201492109A1 (ru) | 2015-07-30 |
| JP2015517525A (ja) | 2015-06-22 |
| US20200138909A1 (en) | 2020-05-07 |
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