CN1183133C - 2-氨基-6-苯胺基-嘌呤及其作为药物的用途 - Google Patents

2-氨基-6-苯胺基-嘌呤及其作为药物的用途 Download PDF

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Publication number
CN1183133C
CN1183133C CNB008038155A CN00803815A CN1183133C CN 1183133 C CN1183133 C CN 1183133C CN B008038155 A CNB008038155 A CN B008038155A CN 00803815 A CN00803815 A CN 00803815A CN 1183133 C CN1183133 C CN 1183133C
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CN
China
Prior art keywords
amino
phenyl
ethyl
purine
base
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Expired - Fee Related
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CNB008038155A
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English (en)
Chinese (zh)
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CN1340054A (zh
Inventor
P
P·因巴奇
H-G·卡普拉罗
J·金莫曼
G·卡拉瓦蒂
P·弗雷特
W·K－D·布里尔
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Novartis AG
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Novartis AG
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Publication of CN1340054A publication Critical patent/CN1340054A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CNB008038155A 1999-02-18 2000-02-16 2-氨基-6-苯胺基-嘌呤及其作为药物的用途 Expired - Fee Related CN1183133C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9903762.4 1999-02-18
GBGB9903762.4A GB9903762D0 (en) 1999-02-18 1999-02-18 Organic compounds

Publications (2)

Publication Number Publication Date
CN1340054A CN1340054A (zh) 2002-03-13
CN1183133C true CN1183133C (zh) 2005-01-05

Family

ID=10848053

Family Applications (1)

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CNB008038155A Expired - Fee Related CN1183133C (zh) 1999-02-18 2000-02-16 2-氨基-6-苯胺基-嘌呤及其作为药物的用途

Country Status (13)

Country Link
US (1) US6767906B2 (https=)
EP (1) EP1153024B1 (https=)
JP (1) JP2002537300A (https=)
CN (1) CN1183133C (https=)
AT (1) ATE265456T1 (https=)
AU (1) AU3804500A (https=)
BR (1) BR0008365A (https=)
CA (1) CA2360353A1 (https=)
DE (1) DE60010234T2 (https=)
ES (1) ES2219326T3 (https=)
GB (1) GB9903762D0 (https=)
PT (1) PT1153024E (https=)
WO (1) WO2000049018A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101148449B (zh) * 2006-09-20 2010-08-11 浙江医药股份有限公司新昌制药厂 2-(6-喹啉氨基)-6-环丙氨基-9h-嘌呤成盐的方法

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DE60010234T2 (de) 2005-04-14
DE60010234D1 (de) 2004-06-03
CA2360353A1 (en) 2000-08-24
ES2219326T3 (es) 2004-12-01
JP2002537300A (ja) 2002-11-05
GB9903762D0 (en) 1999-04-14
ATE265456T1 (de) 2004-05-15
HK1042479A1 (en) 2002-08-16
AU3804500A (en) 2000-09-04
US6767906B2 (en) 2004-07-27
CN1340054A (zh) 2002-03-13
EP1153024A1 (en) 2001-11-14
BR0008365A (pt) 2001-11-13
PT1153024E (pt) 2004-08-31
EP1153024B1 (en) 2004-04-28
US20020016329A1 (en) 2002-02-07
WO2000049018A1 (en) 2000-08-24

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Termination date: 20100216