CN1175258A - 用作抗病毒药的噻吩并 嗪酮类衍生物 - Google Patents

用作抗病毒药的噻吩并 嗪酮类衍生物 Download PDF

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Publication number
CN1175258A
CN1175258A CN95197615A CN95197615A CN1175258A CN 1175258 A CN1175258 A CN 1175258A CN 95197615 A CN95197615 A CN 95197615A CN 95197615 A CN95197615 A CN 95197615A CN 1175258 A CN1175258 A CN 1175258A
Authority
CN
China
Prior art keywords
compound
cbz
carbobenzoxy
amino
exchange
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN95197615A
Other languages
English (en)
Chinese (zh)
Inventor
R·L·扎维斯特
M·J·帕列特
H·T·塞拉菲诺瓦斯卡
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of CN1175258A publication Critical patent/CN1175258A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oncology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN95197615A 1994-12-22 1995-12-20 用作抗病毒药的噻吩并 嗪酮类衍生物 Pending CN1175258A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9426021.3 1994-12-22
GBGB9426021.3A GB9426021D0 (en) 1994-12-22 1994-12-22 Pharmaceuticals

Publications (1)

Publication Number Publication Date
CN1175258A true CN1175258A (zh) 1998-03-04

Family

ID=10766452

Family Applications (1)

Application Number Title Priority Date Filing Date
CN95197615A Pending CN1175258A (zh) 1994-12-22 1995-12-20 用作抗病毒药的噻吩并 嗪酮类衍生物

Country Status (14)

Country Link
EP (1) EP0799230A1 (no)
JP (1) JPH11500710A (no)
CN (1) CN1175258A (no)
AU (1) AU4347596A (no)
BR (1) BR9510418A (no)
CA (1) CA2208458A1 (no)
CZ (1) CZ195897A3 (no)
FI (1) FI972585A (no)
GB (1) GB9426021D0 (no)
HU (1) HUT77123A (no)
NO (1) NO972905L (no)
PL (1) PL320889A1 (no)
WO (1) WO1996019482A1 (no)
ZA (1) ZA9510823B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1595997A (en) * 1996-01-26 1997-08-20 Smithkline Beecham Plc Thienoxazinone derivatives useful as antiviral agents
GB9601544D0 (en) 1996-01-26 1996-03-27 Smithkline Beecham Plc Pharmaceuticals
WO1997048707A1 (en) * 1996-06-20 1997-12-24 Smithkline Beecham Plc 4h-3,1-benzoxazin-4-one derivatives and analogs as antiviral agents
WO1998045298A1 (en) * 1997-04-10 1998-10-15 Smithkline Beecham Plc Antiviral agents
GB9710928D0 (en) * 1997-05-29 1997-07-23 Smithkline Beecham Plc Pharmaceuticals
EP1467978A4 (en) 2001-12-20 2005-11-02 Osi Pharm Inc "COMPOUNDS THAT CONTAIN VACCINATES DRUG LIPASE, THEIR SYNTHESIS AND USE"

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3681351A (en) * 1970-04-15 1972-08-01 Ian Wellings CERTAIN 5,6,7,8-TETRAHYDRO-5,8-ETHANO-PYRIDINO{8 2,3-b{9 -THIENO{8 5,4-d{9 PYRIMIDINES
CA1094063A (en) * 1977-08-22 1981-01-20 Davis L. Temple, Jr. Thieno ¬2,3-d| pyrimidine antiallergic agents

Also Published As

Publication number Publication date
NO972905L (no) 1997-08-18
CA2208458A1 (en) 1996-06-27
CZ195897A3 (cs) 1998-03-18
PL320889A1 (en) 1997-11-10
FI972585A (fi) 1997-08-19
BR9510418A (pt) 1998-05-19
GB9426021D0 (en) 1995-02-22
WO1996019482A1 (en) 1996-06-27
MX9704737A (es) 1997-10-31
EP0799230A1 (en) 1997-10-08
JPH11500710A (ja) 1999-01-19
FI972585A0 (fi) 1997-06-17
HUT77123A (hu) 1998-03-02
AU4347596A (en) 1996-07-10
ZA9510823B (en) 1996-08-16
NO972905D0 (no) 1997-06-20

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication