CN117042782A - 使用了化学交联海藻酸的多层结构体 - Google Patents

使用了化学交联海藻酸的多层结构体 Download PDF

Info

Publication number
CN117042782A
CN117042782A CN202180087544.4A CN202180087544A CN117042782A CN 117042782 A CN117042782 A CN 117042782A CN 202180087544 A CN202180087544 A CN 202180087544A CN 117042782 A CN117042782 A CN 117042782A
Authority
CN
China
Prior art keywords
alginic acid
formula
group
chemically modified
represented
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202180087544.4A
Other languages
English (en)
Chinese (zh)
Inventor
古迫正司
津田直人
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mochida Pharmaceutical Co Ltd
Original Assignee
Mochida Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mochida Pharmaceutical Co Ltd filed Critical Mochida Pharmaceutical Co Ltd
Publication of CN117042782A publication Critical patent/CN117042782A/zh
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/20Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28Polysaccharides or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/44Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/26Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/042Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606Coatings
    • A61L2300/608Coatings having two or more layers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/62Encapsulated active agents, e.g. emulsified droplets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/64Animal cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN202180087544.4A 2020-12-28 2021-12-27 使用了化学交联海藻酸的多层结构体 Pending CN117042782A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020219024 2020-12-28
JP2020-219024 2020-12-28
PCT/JP2021/048566 WO2022145419A1 (ja) 2020-12-28 2021-12-27 化学架橋アルギン酸を用いた多層構造体

Publications (1)

Publication Number Publication Date
CN117042782A true CN117042782A (zh) 2023-11-10

Family

ID=82260785

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180087544.4A Pending CN117042782A (zh) 2020-12-28 2021-12-27 使用了化学交联海藻酸的多层结构体

Country Status (5)

Country Link
US (1) US20240342340A1 (https=)
EP (1) EP4268856A4 (https=)
JP (1) JPWO2022145419A1 (https=)
CN (1) CN117042782A (https=)
WO (1) WO2022145419A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116710110A (zh) * 2020-12-28 2023-09-05 持田制药株式会社 新型的多层聚合物涂层交联海藻酸凝胶纤维

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019240219A1 (ja) * 2018-06-14 2019-12-19 持田製薬株式会社 新規な架橋アルギン酸

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4663286A (en) * 1984-02-13 1987-05-05 Damon Biotech, Inc. Encapsulation of materials
US5589591A (en) 1986-07-03 1996-12-31 Advanced Magnetics, Inc. Endotoxin-free polysaccharides
WO1993013136A1 (en) 1991-12-20 1993-07-08 Howmedica Inc. Ultra-pure polysaccharide materials for medical use
JPH08269102A (ja) 1995-03-30 1996-10-15 Shiseido Co Ltd エンドトキシンフリーのβ1,3−グルカン及びその製造法並びに医療用ゲル素材
JPH09324001A (ja) 1996-04-02 1997-12-16 Kyowa Hakko Kogyo Co Ltd ヒアルロン酸ナトリウムの精製法
US6281341B1 (en) 1997-04-30 2001-08-28 Biomm, Inc. & University Of Miami Hetero-polysaccharide conjugate and methods of making and using the same
AU780366B2 (en) 2000-01-20 2005-03-17 Diatranz Otsuka Limited Preparation and xenotransplantation of porcine islets
JP4676880B2 (ja) 2002-10-21 2011-04-27 ジボダン エス エー シクロオクト−(エン−)イル誘導体の香料としての使用
JP2005036036A (ja) 2003-07-16 2005-02-10 Tanabe Seiyaku Co Ltd エンドトキシン除去方法
JP4986273B2 (ja) 2005-09-15 2012-07-25 持田製薬株式会社 アルギン酸を含む創傷被覆材
US8815283B2 (en) 2009-06-02 2014-08-26 Mcmaster University Immuno-compatible hydrogel system
US9090868B2 (en) * 2010-07-12 2015-07-28 President And Fellows Of Harvard College Alginate hydrogel fibers and related materials
EP2680862B1 (en) * 2011-03-04 2016-07-20 Wake Forest University Health Sciences Encapsulated cells for hormone replacement therapy
CN103981147B (zh) * 2013-02-08 2017-11-10 中国科学院上海生命科学研究院 一种新的制备肝实质细胞的方法
WO2014171842A1 (en) 2013-04-19 2014-10-23 Living Cell Technologies New Zealand Limited Biocompatible encapsulation system
US20170080391A1 (en) 2014-03-19 2017-03-23 E.W. - Hydrophilic Processes Ltd. Highly efficient reverse osmosis filter
CN105078923A (zh) 2014-05-07 2015-11-25 中国科学院大连化学物理研究所 Peg原位共价接枝的海藻酸盐微胶囊及其制备和应用
US11655343B2 (en) * 2016-03-24 2023-05-23 Takeda Pharmaceutical Company Limited Alginate hydrogel compositions
SG11201811763SA (en) * 2016-07-18 2019-02-27 Eth Zuerich B-cell-mimetic cells
KR20190118181A (ko) 2017-02-16 2019-10-17 아지노모토 가부시키가이샤 폴리머 비드
JP7346380B2 (ja) 2018-02-28 2023-09-19 持田製薬株式会社 新規光架橋性アルギン酸誘導体
CN114929754A (zh) 2019-12-18 2022-08-19 持田制药株式会社 新型交联海藻酸

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019240219A1 (ja) * 2018-06-14 2019-12-19 持田製薬株式会社 新規な架橋アルギン酸

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
HASAN ULUDAG 等: "Technology of mammalian cell encapsulation", 《ADVANCED DRUG DELIVERY REVIEWS》, vol. 42, 31 December 2000 (2000-12-31), pages 29 - 64 *

Also Published As

Publication number Publication date
JPWO2022145419A1 (https=) 2022-07-07
EP4268856A1 (en) 2023-11-01
US20240342340A1 (en) 2024-10-17
EP4268856A4 (en) 2025-09-24
WO2022145419A1 (ja) 2022-07-07

Similar Documents

Publication Publication Date Title
AU2019200810B2 (en) Modified alginates for anti-fibrotic materials and applications
JP7210095B2 (ja) 化学架橋アルギン酸を用いた移植用デバイス
CN112236457B (zh) 新型交联海藻酸
JP2019509387A (ja) ジェランガムヒドロゲル、調製物、方法、およびそれらの使用
JP7704952B2 (ja) 新規な架橋アルギン酸
JP2015040276A (ja) 生分解性ポリマーと粘土鉱物とを複合してなるヒドロゲル化剤
JP7346380B2 (ja) 新規光架橋性アルギン酸誘導体
Zhou et al. An injectable carboxymethyl chitosan-based hydrogel with controlled release of BMP-2 for efficient treatment of bone defects
CN117042782A (zh) 使用了化学交联海藻酸的多层结构体
JP7625014B2 (ja) 化学架橋アルギン酸を用いた移植用デバイス
JP2025131662A (ja) 新規な架橋アルギン酸構造体
HUE031774T2 (en) Crosslinked hyaluronic acid derivatives, process and their use
CN116406394B (zh) 可交联的烯丙基酰氨基聚合物
Tsou Enzyme-Assisted Development of Hydrogels As Medical Materials With Injectable, Biodegradable and Biocompatible Properties
CAMANA et al. Synthesis and characterisation of Pluronic hydrogels for biomedical applications

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination