CN1169811C - 合成(3aS)-5,5-二氧代-2,3,3a,4-四氢-1H-吡咯并[2,1-c][1,2,4]苯并噻二嗪的新方法 - Google Patents

合成(3aS)-5,5-二氧代-2,3,3a,4-四氢-1H-吡咯并[2,1-c][1,2,4]苯并噻二嗪的新方法 Download PDF

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Publication number
CN1169811C
CN1169811C CNB021057907A CN02105790A CN1169811C CN 1169811 C CN1169811 C CN 1169811C CN B021057907 A CNB021057907 A CN B021057907A CN 02105790 A CN02105790 A CN 02105790A CN 1169811 C CN1169811 C CN 1169811C
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China
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formula
compound
pyrrolo
dioxo
mol
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Expired - Fee Related
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CNB021057907A
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English (en)
Chinese (zh)
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CN1381455A (zh
Inventor
E�����ж�
E·福切尔
��˹��ŵ��
G·托米诺特
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J-P·勒库夫
J·A·兰斯登
C·J·考布里
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Les Laboratoires Servier SAS
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Les Laboratoires Servier SAS
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CNB021057907A 2001-04-18 2002-04-18 合成(3aS)-5,5-二氧代-2,3,3a,4-四氢-1H-吡咯并[2,1-c][1,2,4]苯并噻二嗪的新方法 Expired - Fee Related CN1169811C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0105226A FR2823753B1 (fr) 2001-04-18 2001-04-18 Nouveau procede de synthese de la (3as)-5,5-dioxo-2,3,3a, 4-tetrahydro-1h-pyrrolo [2,1-c] [1,2,4] benzothiadiazine
FR0105226 2001-04-18

Publications (2)

Publication Number Publication Date
CN1381455A CN1381455A (zh) 2002-11-27
CN1169811C true CN1169811C (zh) 2004-10-06

Family

ID=8862416

Family Applications (1)

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CNB021057907A Expired - Fee Related CN1169811C (zh) 2001-04-18 2002-04-18 合成(3aS)-5,5-二氧代-2,3,3a,4-四氢-1H-吡咯并[2,1-c][1,2,4]苯并噻二嗪的新方法

Country Status (23)

Country Link
US (1) US6518422B2 (https=)
EP (1) EP1251132B1 (https=)
JP (1) JP4011956B2 (https=)
KR (1) KR100468066B1 (https=)
CN (1) CN1169811C (https=)
AR (1) AR036871A1 (https=)
AT (1) ATE269339T1 (https=)
AU (1) AU782080B2 (https=)
BR (1) BR0201307A (https=)
CA (1) CA2382405C (https=)
DE (1) DE60200627T2 (https=)
DK (1) DK1251132T3 (https=)
EA (1) EA004927B1 (https=)
ES (1) ES2223031T3 (https=)
FR (1) FR2823753B1 (https=)
HU (1) HUP0201256A3 (https=)
MX (1) MXPA02003639A (https=)
NO (1) NO20021768L (https=)
NZ (1) NZ518422A (https=)
PL (1) PL353512A1 (https=)
PT (1) PT1251132E (https=)
SI (1) SI1251132T1 (https=)
ZA (1) ZA200203085B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2856065B1 (fr) * 2003-06-13 2005-08-19 Servier Lab Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US20060014887A1 (en) * 2004-07-19 2006-01-19 3M Innovative Properties Company Method of hydrolyzing a dispersion of ionic fluoropolymer
FR2879201B1 (fr) * 2004-12-10 2007-02-16 Servier Lab Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DK2230094T3 (en) 2009-03-20 2014-03-03 Kremstal Tuerenwerk Gmbh Process for coating of panels

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3294791A (en) * 1966-03-14 1966-12-27 American Home Prod Tetrahydro-2, 5-methano-1, 2, 5-benzothiadiazepine 1, 1-dioxide
US3471483A (en) * 1967-11-09 1969-10-07 American Home Prod 1 - substituted - 2,3,3a - 4 - tetrahydro - 1h-pyrrolo(2,1 - c)(1,2,4)benzothiadiazine,5,5-dioxide
JPH06192272A (ja) * 1992-12-24 1994-07-12 Japan Tobacco Inc 新規なトリアゾロベンゾチアジアジン及びトリアゾロベンゾチアジアゼピン誘導体
FR2722502B1 (fr) * 1994-07-12 1996-08-23 Adir Nouveau derive de benzothiadiazine, son procede depreparation et les compositions pharmaceutiques qui le contiennent
FR2812291B1 (fr) * 2000-07-28 2002-12-13 Adir Nouveaux derives de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
US20020161222A1 (en) 2002-10-31
DK1251132T3 (da) 2004-10-25
HUP0201256A2 (hu) 2002-12-28
CA2382405C (fr) 2007-03-06
JP2003012674A (ja) 2003-01-15
SI1251132T1 (en) 2004-10-31
KR100468066B1 (ko) 2005-01-24
AU3440502A (en) 2002-10-24
ES2223031T3 (es) 2005-02-16
EP1251132B1 (fr) 2004-06-16
NO20021768L (no) 2002-10-21
EP1251132A1 (fr) 2002-10-23
EA200200378A2 (ru) 2002-10-31
EA004927B1 (ru) 2004-10-28
EA200200378A3 (ru) 2002-12-26
ZA200203085B (en) 2002-11-25
DE60200627D1 (de) 2004-07-22
JP4011956B2 (ja) 2007-11-21
NZ518422A (en) 2002-12-20
DE60200627T2 (de) 2005-07-14
NO20021768D0 (no) 2002-04-15
AR036871A1 (es) 2004-10-13
HUP0201256A3 (en) 2004-11-29
BR0201307A (pt) 2003-06-10
PL353512A1 (en) 2002-10-21
US6518422B2 (en) 2003-02-11
HK1049668A1 (en) 2003-05-23
CA2382405A1 (fr) 2002-10-18
PT1251132E (pt) 2004-09-30
ATE269339T1 (de) 2004-07-15
MXPA02003639A (es) 2004-11-12
FR2823753B1 (fr) 2004-07-16
HU0201256D0 (https=) 2002-06-29
CN1381455A (zh) 2002-11-27
KR20020081148A (ko) 2002-10-26
AU782080B2 (en) 2005-06-30
FR2823753A1 (fr) 2002-10-25

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Granted publication date: 20041006