CN116898910A - A topical Chinese medicinal composition for treating children chronic cough, and its preparation method - Google Patents

A topical Chinese medicinal composition for treating children chronic cough, and its preparation method Download PDF

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CN116898910A
CN116898910A CN202311066386.1A CN202311066386A CN116898910A CN 116898910 A CN116898910 A CN 116898910A CN 202311066386 A CN202311066386 A CN 202311066386A CN 116898910 A CN116898910 A CN 116898910A
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parts
traditional chinese
chinese medicine
cough
wind
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甘旗旗
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Xi'an Xd Group Hospital
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Xi'an Xd Group Hospital
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Abstract

The invention discloses an external traditional Chinese medicine composition for treating children chronic cough and a preparation method thereof, and relates to the technical field of preparation of traditional Chinese medicine external products, wherein the external traditional Chinese medicine composition comprises an external traditional Chinese medicine composition for treating wind-heat cough and an external traditional Chinese medicine composition for treating wind-cold cough; the external traditional Chinese medicine composition for treating wind-heat cough comprises the following raw materials: honeysuckle, creeping oxalis, weeping forsythiae capsule, watermelon vine, origanum vulgare, yellow Pi He, wild buckwheat rhizome, dysosma versipellis, cordate houttuynia, horseshoe gold, loquat leaf, luffa, gypsum and liquorice; the external traditional Chinese medicine composition for treating cough due to wind-cold evil comprises the following raw materials: herba Schizonepetae, semen oryzae sativae, perillae herba, rhizoma Kaempferiae, calyx kaki, radix Saposhnikoviae, flos Caryophylli, fructus Litseae, herba Ocimi, pericarpium Pyri, rhizoma Cynanchi Stauntonii, radix Platycodi, semen Cucurbitae, lignum Cinnamomi Camphorae, and cortex Cinnamomi. The external traditional Chinese medicine composition has good treatment effect and definite curative effect on children chronic cough, and the medicine is mild, has no stimulation and no toxic or side effect.

Description

A topical Chinese medicinal composition for treating children chronic cough, and its preparation method
Technical Field
The invention relates to the technical field of preparation of external traditional Chinese medicine products, in particular to an external traditional Chinese medicine composition for treating children chronic cough and a preparation method thereof.
Background
Chronic cough in children is a cough which is mainly or exclusively clinically manifested and has no obvious abnormality in chest X-ray film after the course of disease is more than 4 weeks. The chronic cough has important influence on physical and mental health of children, and has important significance for diagnosing, treating and managing the chronic cough of children. However, there is currently no specific therapeutic drug for pediatric chronic cough, and there is a lack of standardized management.
The Chinese herbal medicine is a treasure in China, the effect of treating both principal and secondary aspect of diseases can be achieved by reasonably using the Chinese herbal medicine to treat the diseases, and the Chinese herbal medicine has the characteristics of high safety, no toxic or side effect and difficult generation of drug resistance. However, due to poor taste and smell of traditional Chinese medicine, children have poor compliance for oral administration, and vomit is easy to cause after taking the medicine, so that the administration dosage is difficult to ensure, and therefore, traditional Chinese medicine preparations are less adopted in treating children chronic cough.
The external treatment method of the traditional Chinese medicine is one of the treatment methods with special effects of the traditional Chinese medicine, has the advantages of convenient use, obvious curative effect and no pain, accords with the characteristics of oral administration and injection administration of fear of children, and is an ideal administration way for pediatrics. Based on the above, the external traditional Chinese medicine composition for treating children chronic cough, which has good treatment effect, quick response and no side effect, is a technical problem which needs to be solved by the people in the field.
Disclosure of Invention
Aiming at the problems, the invention provides an external traditional Chinese medicine composition for treating children chronic cough and a preparation method thereof.
In order to achieve the above purpose, the technical scheme adopted by the invention is as follows:
the invention provides an external traditional Chinese medicine composition for treating children chronic cough, which comprises an external traditional Chinese medicine composition for treating wind-heat cough and an external traditional Chinese medicine composition for treating wind-cold cough;
the external traditional Chinese medicine composition for treating wind-heat cough comprises the following raw materials in parts by weight: 6-10 parts of honeysuckle, 1-3 parts of oxalis, 4-6 parts of fructus forsythiae, 1-3 parts of watermelon vine, 1-3 parts of origanum vulgare, 1-3 parts of wampee core, 2-4 parts of wild buckwheat rhizome, 2-4 parts of dysosma versipellis, 3-5 parts of cordate houttuynia, 1-3 parts of horseshoe gold, 1-3 parts of loquat leaf, 1-3 parts of loofah sponge, 2-4 parts of gypsum and 1-3 parts of liquorice;
the external traditional Chinese medicine composition for treating cough due to wind-cold evil comprises the following raw materials in parts by weight: 4-8 parts of schizonepeta, 3-5 parts of taibai rice, 1-3 parts of perilla, 1-3 parts of taro, 1-3 parts of calyx kaki, 2-4 parts of radix sileris, 2-4 parts of mother clove, 3-5 parts of fructus cubeba, 2-4 parts of basil, 1-3 parts of pear peel, 1-3 parts of cynomorium songaricum, 2-4 parts of platycodon grandiflorum, 1-3 parts of pumpkin seed, 2-4 parts of camphorwood and 1-3 parts of cinnamon.
Further, the external traditional Chinese medicine composition for treating wind-heat cough comprises the following raw materials in parts by weight: 8 parts of honeysuckle, 2 parts of oxalis, 5 parts of weeping forsythiae capsule, 2 parts of watermelon vine, 2 parts of origanum vulgare, 2 parts of wampee core, 3 parts of wild buckwheat rhizome, 3 parts of dysosma versipellis, 4 parts of cordate houttuynia, 2 parts of horseshoe gold, 2 parts of loquat leaf, 2 parts of luffa, 3 parts of gypsum and 2 parts of liquorice;
the external traditional Chinese medicine composition for treating cough due to wind-cold evil comprises the following raw materials in parts by weight: 6 parts of schizonepeta, 4 parts of taibai rice, 2 parts of perilla, 2 parts of henry steudnera tuber, 2 parts of persimmon calyx, 3 parts of divaricate saposhnikovia root, 3 parts of mother clove, 4 parts of fructus cubeba, 3 parts of basil, 2 parts of pear peel, 2 parts of water-oriented yang, 3 parts of platycodon grandiflorum, 2 parts of pumpkin seed, 3 parts of camphorwood and 2 parts of cinnamon.
Further, the external traditional Chinese medicine composition for wind-heat cough is applied to children chronic wind-heat cough, and the external traditional Chinese medicine composition for wind-cold cough is applied to children chronic wind-cold cough.
Further, the application method of the external traditional Chinese medicine composition comprises the following steps: the Chinese medicinal composition is applied to the acupoints of the two lateral acupoints of children, dazhui acupoint and Feishu acupoint once a day for 4-6 hr each time.
The invention also provides a preparation method of the external traditional Chinese medicine composition for treating children chronic cough, which specifically comprises the following steps:
s1: weighing the raw materials of the externally-applied traditional Chinese medicine composition for treating cough due to wind-heat according to parts by weight: 6-10 parts of honeysuckle, 1-3 parts of oxalis, 4-6 parts of fructus forsythiae, 1-3 parts of watermelon vine, 1-3 parts of origanum vulgare, 1-3 parts of wampee core, 2-4 parts of wild buckwheat rhizome, 2-4 parts of dysosma versipellis, 3-5 parts of cordate houttuynia, 1-3 parts of horseshoe gold, 1-3 parts of loquat leaf, 1-3 parts of loofah sponge, 2-4 parts of gypsum and 1-3 parts of liquorice; weighing the raw materials of the external traditional Chinese medicine composition for treating cough due to wind-cold evil according to parts by weight: 4-8 parts of schizonepeta, 3-5 parts of taibai rice, 1-3 parts of perilla, 1-3 parts of taro, 1-3 parts of calyx kaki, 2-4 parts of radix sileris, 2-4 parts of mother clove, 3-5 parts of fructus cubeba, 2-4 parts of basil, 1-3 parts of pear peel, 1-3 parts of cynomorium songaricum, 2-4 parts of platycodon grandiflorum, 1-3 parts of pumpkin seed, 2-4 parts of camphorwood and 1-3 parts of cinnamon;
s2: mixing the raw materials of the external traditional Chinese medicine composition for treating wind-heat cough and the raw materials of the external traditional Chinese medicine composition for treating wind-cold cough in the step S1 respectively, crushing, sieving and drying to obtain wind-heat mixed medicine and wind-cold mixed medicine respectively;
s3: mixing rhizoma Zingiberis recens with water, boiling, and filtering to obtain rhizoma Zingiberis recens juice;
s4: respectively adding rhizoma Zingiberis recens juice into the wind-heat mixed medicine and the wind-cold mixed medicine, and stirring to obtain paste medicines; the pasty medicines are respectively smeared on the blank medicine patches to form round medicines, and the external traditional Chinese medicine composition for treating wind-heat cough and the external traditional Chinese medicine composition for treating wind-cold cough are obtained.
Further, in the step S2, the sieving number is 100-120 meshes.
Further, in the step S3, the mass ratio of the ginger to the water is 1:5, and the boiling time is 20-30min
Further, in the step S4, the mass ratio of the wind-heat mixed medicine to the ginger juice is 6:1, and the mass ratio of the wind-cold mixed medicine to the ginger juice is 6:1; the diameter of the round medicament is 3cm, and the thickness is 0.5cm.
According to the compatibility theory of monarch, minister, assistant and guide, the externally-applied traditional Chinese medicine composition for treating children chronic cough takes honeysuckle and weeping forsythiae as monarch drugs, has the effects of detumescence, resolving hard mass and dispelling wind and heat, and can treat headache, fever, thirst, pharyngalgia and the like in the early stage of wind-heat exogenous warm disease; herba Houttuyniae, rhizoma Fagopyri Dibotryis, radix et rhizoma Dysosmatis, gypsum Fibrosum, and herba Oxalidis Corniculatae as ministerial drugs, and has effects of clearing heat, removing toxic substances, expelling pus, removing blood stasis, eliminating phlegm, and relieving cough; the watermelon vine, wampee core, origanum vulgare, horseshoe gold, loquat leaf and luffa are taken as adjuvant drugs, and have the effects of clearing heat, detoxicating, moistening lung and relieving cough; glycyrrhrizae radix is used as a guiding drug, and has effects of invigorating spleen and replenishing qi, relieving cough and eliminating phlegm, harmonizing drug property, etc. In the external traditional Chinese medicine composition for treating cough due to wind-cold evil, schizonepeta and fructus cubeba are taken as monarch drugs, and the external traditional Chinese medicine composition has the effects of relieving exterior syndrome, dispelling wind, relieving chest stuffiness, promoting qi circulation, relieving cough and asthma and the like; the ether rice, the mother clove, the basil, the radix sileris, the platycodon grandiflorum and the camphorwood are taken as ministerial drugs, has effects of relieving exterior syndrome, dispelling cold, lowering adverse flow of qi, stopping singultus, relieving sore throat, and expelling pus; the yam, purple perilla, calyx kaki, water-logging sun, pear peel and pumpkin seed are taken as adjuvant drugs, and have the effects of moistening lung, relieving cough, strengthening intestines, relieving diarrhea, relieving drug intensity and the like; cinnamon is used as a guiding drug, and has the effects of dispelling cold, relieving pain, warming and activating meridians, harmonizing drug property and the like. The pharmacological actions of the traditional Chinese medicine raw materials are as follows:
honeysuckle flower: can be used for treating wind-heat type common cold, laryngopharynx inflammation, pertussis, etc., and has effects of clearing heat and detoxicating, cooling and dispelling wind-heat;
oxalis (L.) Ohwi: can be used for treating common cold, fever, sore throat, etc., and has effects of clearing heat, promoting diuresis, cooling blood, removing blood stasis, removing toxic substances, and detumescence;
fructus forsythiae: can be used for treating wind-heat type common cold, warming and camping, and has effects of clearing heat and detoxicating, detumescence and resolving hard mass;
watermelon vine: has effects of clearing heat and detoxicating;
oregano: can be used for treating common cold, fever, heatstroke, etc., and has effects of relieving exterior syndrome, regulating qi-flowing, clearing summerheat, and promoting diuresis;
cortex Phellodendri kernel: can be used for treating phlegm cough asthma, and has effects of regulating qi-flowing, resolving hard mass, relieving distention, eliminating phlegm, relieving cough, etc.;
wild buckwheat rhizome: can be used for treating lung abscess, laryngopharynx swelling and pain, lung heat cough and asthma caused by heat toxin, and has effects of clearing heat and detoxicating, expelling pus and removing blood stasis;
dysosma versipellis: mainly treats cough, sore throat and the like, has the effects of resolving phlegm, resolving masses, removing stasis, relieving pain, clearing heat and detoxicating and the like;
cordate houttuynia: can be used for treating cough due to phlegm heat, pneumonia and edema, and has effects of clearing heat and detoxicating;
radix et rhizoma Rhei: has effects of clearing heat, promoting diuresis, removing toxic substances, and relieving swelling;
loquat leaves: can be used for treating cough due to lung heat, asthma, vomiting due to stomach heat, dysphoria with smothery sensation, thirst, lung moistening, cough relieving, adverse rising energy, and emesis relieving;
loofah sponge: can be used for treating qi and blood stagnation, cough due to lung heat, etc., and has effects of promoting blood circulation, dredging collaterals, dispelling pathogenic wind, etc.;
gypsum: can be used for treating infantile fever, cough, excessive phlegm, etc., and has effects of clearing heat, lowering fire, relieving restlessness, quenching thirst, etc.;
cinnamon: has effects of dispelling cold, relieving pain, warming and dredging channels.
Licorice root: can be used for treating lung heat laryngalgia, cough and asthma, etc., and has effects of invigorating spleen and replenishing qi, relieving cough and eliminating phlegm, relieving spasm and pain, and harmonizing drug property;
herba schizonepetae: can be used for treating common cold, headache, etc., and has effects of relieving exterior syndrome, dispelling pathogenic wind, promoting eruption, etc.;
the rice is: is mainly used for treating cough due to wind-cold evil, relieving pain and eliminating phlegm, and has the effects of relieving chest stuffiness, promoting qi circulation, invigorating stomach, relieving vomiting, relieving pain, relieving cough and the like;
perilla frutescens (L.) f: can be used for treating common cold due to wind-cold, cough, nausea, etc., and has effects of relieving exterior syndrome, dispelling cold, activating qi-flowing, regulating stomach function, etc.;
taro: can be used for treating common cold, headache, and tiredness;
calyx kaki: can be used for treating typhoid fever, cough, chest distress, and hiccup;
wind prevention: can be used for treating common cold, fever, emesis, abdominal pain, etc., and has effects of dispelling pathogenic wind and removing dampness;
mother clove: has effects in warming middle warmer, lowering adverse qi, dispelling cold, and relieving pain;
fructus Litseae: mainly treats the hiccup with typhoid fever and hiccup day and night, and has the effects of warming middle-jiao, dispelling cold, relieving cough and asthma;
basil (Ocimum basilicum L.): can be used for treating common cold due to wind-cold, headache, chest distress, etc., and has effects of dispelling pathogenic wind, promoting qi circulation, eliminating dampness, resolving food stagnation, etc.;
pear peel: has effects of moistening lung, relieving cough, relieving diarrhea, etc.;
water facing sun: is used for treating headache due to wind-cold, toothache, cough and asthma, etc., and has effects of dispelling pathogenic wind, improving eyesight, eliminating phlegm, and softening hard masses;
radix Platycodi: mainly treats cough with excessive phlegm, sore throat and the like, has the effects of dispersing lung qi, eliminating phlegm, relieving sore throat, expelling pus and the like;
pumpkin seed: can be used for treating pertussis, etc.;
camphorwood: is mainly used for treating wind-cold type common cold, stomach cold distending pain, cold dampness vomiting and diarrhea, wind-damp arthralgia, has the effects of dispelling wind and cold, warming middle-jiao and regulating qi, activating blood circulation and removing obstruction in collaterals, and the like;
cinnamon: has effects in dispelling cold, relieving pain, warming and activating meridian, relieving irritation, and regulating drug properties.
Compared with the prior art, the invention has the beneficial effects that:
according to the invention, the external traditional Chinese medicine composition for treating children chronic wind-heat cough is prepared by adopting traditional Chinese medicines with the effects of clearing heat and detoxicating, relieving cough and asthma as raw materials according to the traditional Chinese medicine compatibility theory of monarch, minister, assistant and guide; the external traditional Chinese medicine composition for treating children chronic cough due to wind-cold evil is prepared by adopting traditional Chinese medicines with the effects of relieving exterior syndrome, dispelling wind evil, relieving cough and asthma as raw materials according to the traditional Chinese medicine compatibility theory of 'monarch, minister, assistant and guide'; the external composition is applied to the points of children, so that the children chronic cough can be effectively treated, the discomfort of the children is relieved, and the treatment effect is good in actual use. Clinical verification shows that the external traditional Chinese medicine composition has good treatment effect and definite curative effect on children chronic cough, and the medicine is mild, has no stimulation and no toxic or side effect; in addition, the external traditional Chinese medicine composition disclosed by the invention is simple in preparation process, convenient and safe to use and easy to popularize and use widely.
Detailed Description
The present invention will be described in further detail with reference to examples in order to make the objects and advantages of the present invention more apparent. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the invention.
The instruments, reagents, materials, etc. used in the following examples are conventional instruments, reagents, materials, etc. known in the art, and are commercially available. The experimental methods, detection methods, and the like in the following examples are conventional experimental methods, detection methods, and the like existing in the prior art unless otherwise specified.
Example 1
The embodiment provides an external traditional Chinese medicine composition for treating children chronic cough, which comprises an external traditional Chinese medicine composition for treating wind-heat cough and an external traditional Chinese medicine composition for treating wind-cold cough;
wherein, the liquid crystal display device comprises a liquid crystal display device,
the external traditional Chinese medicine composition for treating wind-heat cough is applied to children chronic wind-heat cough, and comprises the following raw material components in parts by weight: 6 parts of honeysuckle, 1 part of oxalis, 4 parts of fructus forsythiae, 1 part of watermelon vine, 1 part of origanum vulgare, 1 part of wampee core, 2 parts of wild buckwheat rhizome, 2 parts of dysosma versipellis, 3 parts of cordate houttuynia, 1 part of horseshoe gold, 1 part of loquat leaf, 1 part of luffa, 2 parts of gypsum and 1 part of liquorice;
the external traditional Chinese medicine composition for treating wind-cold cough is applied to children with chronic wind-cold cough, and comprises the following raw materials in parts by weight: 4 parts of schizonepeta, 3 parts of taibai rice, 1 part of perilla, 1 part of henry steudnera tuber, 1 part of persimmon calyx, 2 parts of divaricate saposhnikovia root, 2 parts of mother clove, 3 parts of fructus cubeba, 2 parts of basil, 1 part of pear peel, 1 part of water-oriented yang, 2 parts of platycodon grandiflorum, 1 part of pumpkin seed, 2 parts of camphorwood and 1 part of cinnamon.
The application method of the external traditional Chinese medicine composition comprises the following steps: the Chinese medicinal composition is applied to the two side acupoints of children, dazhui acupoint, and Feishu acupoint, once daily for 4 hr.
The embodiment also provides a preparation method of the external traditional Chinese medicine composition for treating children chronic cough, which specifically comprises the following steps:
s1: weighing the raw materials of the externally-applied traditional Chinese medicine composition for treating cough due to wind-heat according to parts by weight: 6 parts of honeysuckle, 1 part of oxalis, 4 parts of fructus forsythiae, 1 part of watermelon vine, 1 part of origanum vulgare, 1 part of wampee core, 2 parts of wild buckwheat rhizome, 2 parts of dysosma versipellis, 3 parts of cordate houttuynia, 1 part of horseshoe gold, 1 part of loquat leaf, 1 part of luffa, 2 parts of gypsum and 1 part of liquorice; weighing the raw materials of the external traditional Chinese medicine composition for treating cough due to wind-cold evil according to parts by weight: 4 parts of schizonepeta, 3 parts of taibai rice, 1 part of perilla, 1 part of henry steudnera tuber, 1 part of persimmon calyx, 2 parts of divaricate saposhnikovia root, 2 parts of mother clove, 3 parts of fructus cubeba, 2 parts of basil, 1 part of pear peel, 1 part of water-oriented yang, 2 parts of platycodon grandiflorum, 1 part of pumpkin seed, 2 parts of camphorwood and 1 part of cinnamon;
s2: mixing the raw materials of the external traditional Chinese medicine composition for treating wind-heat cough and the raw materials of the external traditional Chinese medicine composition for treating wind-cold cough in the step S1 respectively, crushing, sieving with a 100-mesh sieve, and drying to obtain a wind-heat mixed medicine and a wind-cold mixed medicine respectively;
s3: mixing rhizoma Zingiberis recens with 5 times of water, boiling for 20min, and filtering to obtain rhizoma Zingiberis recens juice;
s4: respectively adding 1/6 times of ginger juice into the wind-heat mixed medicine and the wind-cold mixed medicine, and uniformly stirring to obtain pasty medicines; the pasty medicines are respectively smeared on the blank patches to form round medicine with the diameter of 3cm and the thickness of 0.5cm, and the external traditional Chinese medicine composition for treating wind-heat cough and the external traditional Chinese medicine composition for treating wind-cold cough are obtained.
Example 2
The embodiment provides an external traditional Chinese medicine composition for treating children chronic cough, which comprises an external traditional Chinese medicine composition for treating wind-heat cough and an external traditional Chinese medicine composition for treating wind-cold cough;
wherein, the liquid crystal display device comprises a liquid crystal display device,
the external traditional Chinese medicine composition for treating wind-heat cough is applied to children chronic wind-heat cough, and comprises the following raw material components in parts by weight: 8 parts of honeysuckle, 2 parts of oxalis, 5 parts of weeping forsythiae capsule, 2 parts of watermelon vine, 2 parts of origanum vulgare, 2 parts of wampee core, 3 parts of wild buckwheat rhizome, 3 parts of dysosma versipellis, 4 parts of cordate houttuynia, 2 parts of horseshoe gold, 2 parts of loquat leaf, 2 parts of luffa, 3 parts of gypsum and 2 parts of liquorice;
the external traditional Chinese medicine composition for treating wind-cold cough is applied to children with chronic wind-cold cough, and comprises the following raw materials in parts by weight: 6 parts of schizonepeta, 4 parts of taibai rice, 2 parts of perilla, 2 parts of henry steudnera tuber, 2 parts of persimmon calyx, 3 parts of divaricate saposhnikovia root, 3 parts of mother clove, 4 parts of fructus cubeba, 3 parts of basil, 2 parts of pear peel, 2 parts of water-oriented yang, 3 parts of platycodon grandiflorum, 2 parts of pumpkin seed, 3 parts of camphorwood and 2 parts of cinnamon.
The application method of the external traditional Chinese medicine composition comprises the following steps: the Chinese medicinal composition is applied to the two side acupoints of children, dazhui acupoint, and Feishu acupoint, once daily for 5 hr each time.
The embodiment also provides a preparation method of the external traditional Chinese medicine composition for treating children chronic cough, which specifically comprises the following steps:
s1: weighing the raw materials of the externally-applied traditional Chinese medicine composition for treating cough due to wind-heat according to parts by weight: 8 parts of honeysuckle, 2 parts of oxalis, 5 parts of weeping forsythiae capsule, 2 parts of watermelon vine, 2 parts of origanum vulgare, 2 parts of wampee core, 3 parts of wild buckwheat rhizome, 3 parts of dysosma versipellis, 4 parts of cordate houttuynia, 2 parts of horseshoe gold, 2 parts of loquat leaf, 2 parts of luffa, 3 parts of gypsum and 2 parts of liquorice; weighing the raw materials of the external traditional Chinese medicine composition for treating cough due to wind-cold evil according to parts by weight: 6 parts of schizonepeta, 4 parts of taibai rice, 2 parts of perilla, 2 parts of henry steudnera tuber, 2 parts of persimmon calyx, 3 parts of divaricate saposhnikovia root, 3 parts of mother clove, 4 parts of fructus cubeba, 3 parts of basil, 2 parts of pear peel, 2 parts of water-oriented yang, 3 parts of platycodon grandiflorum, 2 parts of pumpkin seed, 3 parts of camphorwood and 2 parts of cinnamon;
s2: mixing the raw materials of the external traditional Chinese medicine composition for treating wind-heat cough and the raw materials of the external traditional Chinese medicine composition for treating wind-cold cough in the step S1 respectively, crushing, sieving with a 115-mesh sieve, and drying to obtain a wind-heat mixed medicine and a wind-cold mixed medicine respectively;
s3: mixing rhizoma Zingiberis recens with 5 times of water, boiling for 25min, and filtering to obtain rhizoma Zingiberis recens juice;
s4: respectively adding 1/6 times of ginger juice into the wind-heat mixed medicine and the wind-cold mixed medicine, and uniformly stirring to obtain pasty medicines; the pasty medicines are respectively smeared on the blank patches to form round medicine with the diameter of 3cm and the thickness of 0.5cm, and the external traditional Chinese medicine composition for treating wind-heat cough and the external traditional Chinese medicine composition for treating wind-cold cough are obtained.
Example 3
The embodiment provides an external traditional Chinese medicine composition for treating children chronic cough, which comprises an external traditional Chinese medicine composition for treating wind-heat cough and an external traditional Chinese medicine composition for treating wind-cold cough;
wherein, the liquid crystal display device comprises a liquid crystal display device,
the external traditional Chinese medicine composition for treating wind-heat cough is applied to children chronic wind-heat cough, and comprises the following raw material components in parts by weight: 10 parts of honeysuckle, 3 parts of oxalis, 6 parts of weeping forsythiae capsule, 3 parts of watermelon vine, 3 parts of origanum vulgare, 3 parts of wampee core, 4 parts of wild buckwheat rhizome, 4 parts of dysosma versipellis, 5 parts of cordate houttuynia, 3 parts of horseshoe gold, 3 parts of loquat leaf, 3 parts of luffa, 4 parts of gypsum and 3 parts of liquorice;
the external traditional Chinese medicine composition for treating wind-cold cough is applied to children with chronic wind-cold cough, and comprises the following raw materials in parts by weight: 8 parts of schizonepeta, 5 parts of taibai rice, 3 parts of perilla, 3 parts of henry steudnera tuber, 3 parts of persimmon calyx, 4 parts of divaricate saposhnikovia root, 4 parts of mother clove, 5 parts of fructus cubeba, 4 parts of basil, 3 parts of pear peel, 3 parts of water-oriented yang, 4 parts of platycodon grandiflorum, 3 parts of pumpkin seed, 4 parts of camphorwood and 3 parts of cinnamon.
The application method of the external traditional Chinese medicine composition comprises the following steps: the Chinese medicinal composition is applied to the two side acupoints of children, dazhui acupoint, and Feishu acupoint, once daily for 6 hr each time.
The embodiment also provides a preparation method of the external traditional Chinese medicine composition for treating children chronic cough, which specifically comprises the following steps:
s1: weighing the raw materials of the externally-applied traditional Chinese medicine composition for treating cough due to wind-heat according to parts by weight: 10 parts of honeysuckle, 3 parts of oxalis, 6 parts of weeping forsythiae capsule, 3 parts of watermelon vine, 3 parts of origanum vulgare, 3 parts of wampee core, 4 parts of wild buckwheat rhizome, 4 parts of dysosma versipellis, 5 parts of cordate houttuynia, 3 parts of horseshoe gold, 3 parts of loquat leaf, 3 parts of luffa, 4 parts of gypsum and 3 parts of liquorice; weighing the raw materials of the external traditional Chinese medicine composition for treating cough due to wind-cold evil according to parts by weight: 8 parts of schizonepeta, 5 parts of taibai rice, 3 parts of perilla, 3 parts of henry steudnera tuber, 3 parts of persimmon calyx, 4 parts of divaricate saposhnikovia root, 4 parts of mother clove, 5 parts of fructus cubeba, 4 parts of basil, 3 parts of pear peel, 3 parts of water-oriented yang, 4 parts of platycodon grandiflorum, 3 parts of pumpkin seed, 4 parts of camphorwood and 3 parts of cinnamon;
s2: mixing the raw materials of the external traditional Chinese medicine composition for treating wind-heat cough and the raw materials of the external traditional Chinese medicine composition for treating wind-cold cough in the step S1 respectively, crushing, sieving with a 120-mesh sieve, and drying to obtain a wind-heat mixed medicine and a wind-cold mixed medicine respectively;
s3: mixing rhizoma Zingiberis recens with 5 times of water, boiling for 30min, and filtering to obtain rhizoma Zingiberis recens juice;
s4: respectively adding 1/6 times of ginger juice into the wind-heat mixed medicine and the wind-cold mixed medicine, and uniformly stirring to obtain pasty medicines; the pasty medicines are respectively smeared on the blank patches to form round medicine with the diameter of 3cm and the thickness of 0.5cm, and the external traditional Chinese medicine composition for treating wind-heat cough and the external traditional Chinese medicine composition for treating wind-cold cough are obtained.
The external traditional Chinese medicine composition for treating children chronic cough of the embodiment is used for clinical test in a lotus lake area peach garden community health service center, and the following specific process and test result of the clinical test are as follows:
1. the experimental object: the children patients with chronic cough in 108 cases are divided into 2 groups according to the open and parallel control principles: 58 treatment groups, 36 men and 22 women, mean age (3.12.+ -. 1.1) years old; control group 50, 29 men and 21 women, mean age (3.08.+ -. 1.15) years old. Age and clinical data of group 2 were statistically not different and comparable.
2. Diagnostic criteria: western diagnosis of all cases is referred to 7 th edition, utility science; the diagnosis of the traditional Chinese medicine refers to the diagnosis standard of cough, pneumonia, asthma and asthma which is related to the traditional Chinese medicine diagnostic curative effect standard of the traditional Chinese medicine syndrome and is established by the national administration.
Of 108 cases of infants, western medicine diagnosis is: 35 cases of bronchitis, 42 cases of bronchopneumonia, 31 cases of asthma and infection. The diagnosis of the Chinese medicine symptoms is as follows: 35 cases of cough, 39 cases of dyspnea and cough of pneumonia and 24 cases of asthma.
3. Inclusion criteria: (1) meets the Western diagnosis standard; (2) the diagnosis of traditional Chinese medicine is met; (3) age 6 months-6 years, and is not limited for men and women; (4) the parents sign informed consent to accept the treatment; (5) after comprehensive treatment such as anti-infection and symptomatic treatment, the patients with excessive phlegm and borborygmus in the throat appear in the recovery period of the disease, which are the selected cases.
4. Exclusion criteria: it can be used for the treatment of all the diseases of bronchial foreign body, tuberculosis infection, bronchopulmonary dysplasia, and liver and kidney.
5. The treatment method comprises the following steps:
(1) Control group: conventional anti-infection is given, and ambroxol is used for intravenous administration, sha Dingan alcohol is used for patients suffering from asthma, ipratropium bromide is used for aerosol inhalation, phlegm resolving, cough relieving and asthma relieving treatment, and glucocorticoid is used for oral administration or intravenous administration for patients suffering from severe asthma.
(2) Treatment group: the external traditional Chinese medicine composition for treating children chronic cough prepared in the embodiment is applied to four acupoints of the double-sided column, the Dazhui and the Feishu of the child, and is applied once a day for 4-6 hours each time, and 3 days is a 1 treatment course. Wherein, the disease is chronic wind-heat cough of children, and the external traditional Chinese medicine composition for treating wind-heat cough is used; the dialectical is chronic cough due to wind-cold evil of children, and the external traditional Chinese medicine composition for treating wind-cold evil is used.
6. And (5) observing index symptoms: cough, wheezing, signs: fine wet roar or wheezing sounds in the lungs.
(1) Standard of efficacy:
and (3) curing: the clinical symptoms disappear after 1 treatment course is finished;
the effect is shown: symptoms and signs disappear or are obviously improved in 1-2 courses of treatment;
the method is effective: after 2 treatment periods are ended, symptoms and signs are improved;
invalidation: after 2 treatment periods are finished, the clinical symptoms and signs are unchanged.
(2) The treatment effect is as follows: one week (2 courses) of treatment were followed for the control and treatment groups, respectively, with the treatment results shown in table 1:
table 1 summary of treatment results
As can be seen from the clinical treatment results, the cure number of the treatment group is 3 in 108 tested children, and the cure number of the treatment group accounts for 5.17% of the total number; the effective number reaches 51, which is 87.93% of the total number, the effective number is 4, which is 6.90% of the total number. The cure number of the control group is 1 person and accounts for 2% of the total number; the effective number reaches 34, accounting for 68 percent of the total number, the effective number is 13, accounting for 26 percent of the total number, the ineffective number is 2, accounting for 4 percent of the total number. Therefore, when the external traditional Chinese medicine composition for treating children chronic cough prepared by the embodiment is applied clinically and practically, 5.17% of children can recover health in 1 treatment course, and 87.93% of children can disappear or obviously improve cough symptoms in 1-2 treatment courses. Therefore, the external traditional Chinese medicine composition for treating children chronic cough of the embodiment is safe and nontoxic, and has good treatment effect, definite curative effect and quick response.
In the embodiment, the external traditional Chinese medicine composition for treating the children chronic wind-heat cough is prepared by adopting traditional Chinese medicines with the effects of clearing heat and detoxicating, relieving cough and relieving asthma as raw materials according to the traditional Chinese medicine compatibility theory of monarch, minister, assistant and guide; the external traditional Chinese medicine composition for treating children chronic cough due to wind-cold evil is prepared by adopting traditional Chinese medicines with the effects of relieving exterior syndrome, dispelling wind evil, relieving cough and asthma as raw materials according to the traditional Chinese medicine compatibility theory of 'monarch, minister, assistant and guide'; the external composition is applied to the points of children, so that the children chronic cough can be effectively treated, the discomfort of the children is relieved, and the treatment effect is good in actual use. Clinical verification shows that the external traditional Chinese medicine composition has good treatment effect and definite curative effect on children chronic cough, and the medicine is mild, has no stimulation and no toxic or side effect; in addition, the external traditional Chinese medicine composition disclosed by the invention is simple in preparation process, convenient and safe to use and easy to popularize and use widely.
The foregoing description of the preferred embodiments of the invention is not intended to limit the invention to the precise form disclosed, and any such modifications, equivalents, and alternatives falling within the spirit and scope of the invention are intended to be included within the scope of the invention.

Claims (8)

1. A traditional Chinese medicine composition for external use for treating children chronic cough is characterized in that: the external traditional Chinese medicine composition comprises an external traditional Chinese medicine composition for treating wind-heat cough and an external traditional Chinese medicine composition for treating wind-cold cough;
the external traditional Chinese medicine composition for treating wind-heat cough comprises the following raw materials in parts by weight: 6-10 parts of honeysuckle, 1-3 parts of oxalis, 4-6 parts of fructus forsythiae, 1-3 parts of watermelon vine, 1-3 parts of origanum vulgare, 1-3 parts of wampee core, 2-4 parts of wild buckwheat rhizome, 2-4 parts of dysosma versipellis, 3-5 parts of cordate houttuynia, 1-3 parts of horseshoe gold, 1-3 parts of loquat leaf, 1-3 parts of loofah sponge, 2-4 parts of gypsum and 1-3 parts of liquorice;
the external traditional Chinese medicine composition for treating cough due to wind-cold evil comprises the following raw materials in parts by weight: 4-8 parts of schizonepeta, 3-5 parts of taibai rice, 1-3 parts of perilla, 1-3 parts of taro, 1-3 parts of calyx kaki, 2-4 parts of radix sileris, 2-4 parts of mother clove, 3-5 parts of fructus cubeba, 2-4 parts of basil, 1-3 parts of pear peel, 1-3 parts of cynomorium songaricum, 2-4 parts of platycodon grandiflorum, 1-3 parts of pumpkin seed, 2-4 parts of camphorwood and 1-3 parts of cinnamon.
2. The topical Chinese medicinal composition for treating chronic cough in children according to claim 1, wherein the composition comprises: the external traditional Chinese medicine composition for treating wind-heat cough comprises the following raw materials in parts by weight: 8 parts of honeysuckle, 2 parts of oxalis, 5 parts of weeping forsythiae capsule, 2 parts of watermelon vine, 2 parts of origanum vulgare, 2 parts of wampee core, 3 parts of wild buckwheat rhizome, 3 parts of dysosma versipellis, 4 parts of cordate houttuynia, 2 parts of horseshoe gold, 2 parts of loquat leaf, 2 parts of luffa, 3 parts of gypsum and 2 parts of liquorice;
the external traditional Chinese medicine composition for treating cough due to wind-cold evil comprises the following raw materials in parts by weight: 6 parts of schizonepeta, 4 parts of taibai rice, 2 parts of perilla, 2 parts of henry steudnera tuber, 2 parts of persimmon calyx, 3 parts of divaricate saposhnikovia root, 3 parts of mother clove, 4 parts of fructus cubeba, 3 parts of basil, 2 parts of pear peel, 2 parts of water-oriented yang, 3 parts of platycodon grandiflorum, 2 parts of pumpkin seed, 3 parts of camphorwood and 2 parts of cinnamon.
3. The topical Chinese medicinal composition for treating chronic cough in children according to claim 1, wherein the composition comprises: the external traditional Chinese medicine composition for treating wind-heat cough is applied to children chronic wind-heat cough, and the external traditional Chinese medicine composition for treating wind-cold cough is applied to children chronic wind-cold cough.
4. The topical Chinese medicinal composition for treating chronic cough in children according to claim 1, wherein the composition comprises: the application method of the external traditional Chinese medicine composition comprises the following steps: the Chinese medicinal composition is applied to the acupoints of the two lateral acupoints of children, dazhui acupoint and Feishu acupoint once a day for 4-6 hr each time.
5. A method for preparing the external traditional Chinese medicine composition for treating children chronic cough according to claim 1, which is characterized in that: the method specifically comprises the following steps:
s1: weighing the raw materials of the externally-applied traditional Chinese medicine composition for treating cough due to wind-heat according to parts by weight: 6-10 parts of honeysuckle, 1-3 parts of oxalis, 4-6 parts of fructus forsythiae, 1-3 parts of watermelon vine, 1-3 parts of origanum vulgare, 1-3 parts of wampee core, 2-4 parts of wild buckwheat rhizome, 2-4 parts of dysosma versipellis, 3-5 parts of cordate houttuynia, 1-3 parts of horseshoe gold, 1-3 parts of loquat leaf, 1-3 parts of loofah sponge, 2-4 parts of gypsum and 1-3 parts of liquorice; weighing the raw materials of the external traditional Chinese medicine composition for treating cough due to wind-cold evil according to parts by weight: 4-8 parts of schizonepeta, 3-5 parts of taibai rice, 1-3 parts of perilla, 1-3 parts of taro, 1-3 parts of calyx kaki, 2-4 parts of radix sileris, 2-4 parts of mother clove, 3-5 parts of fructus cubeba, 2-4 parts of basil, 1-3 parts of pear peel, 1-3 parts of cynomorium songaricum, 2-4 parts of platycodon grandiflorum, 1-3 parts of pumpkin seed, 2-4 parts of camphorwood and 1-3 parts of cinnamon;
s2: mixing the raw materials of the external traditional Chinese medicine composition for treating wind-heat cough and the raw materials of the external traditional Chinese medicine composition for treating wind-cold cough in the step S1 respectively, crushing, sieving and drying to obtain wind-heat mixed medicine and wind-cold mixed medicine respectively;
s3: mixing rhizoma Zingiberis recens with water, boiling, and filtering to obtain rhizoma Zingiberis recens juice;
s4: respectively adding rhizoma Zingiberis recens juice into the wind-heat mixed medicine and the wind-cold mixed medicine, and stirring to obtain paste medicines; the pasty medicines are respectively smeared on the blank medicine patches to form round medicines, and the external traditional Chinese medicine composition for treating wind-heat cough and the external traditional Chinese medicine composition for treating wind-cold cough are obtained.
6. The method for preparing the external traditional Chinese medicine composition for treating children chronic cough according to claim 5, wherein the method is characterized by comprising the following steps: in the step S2, the sieving number is 100-120 meshes.
7. The method for preparing the external traditional Chinese medicine composition for treating children chronic cough according to claim 5, wherein the method is characterized by comprising the following steps: in the step S3, the mass ratio of the ginger to the water is 1:5, and the boiling time is 20-30min.
8. The method for preparing the external traditional Chinese medicine composition for treating children chronic cough according to claim 5, wherein the method is characterized by comprising the following steps: in the step S4, the mass ratio of the wind-heat mixed medicine to the ginger juice is 6:1, and the mass ratio of the wind-heat mixed medicine to the ginger juice is 6:1; the diameter of the round medicament is 3cm, and the thickness is 0.5cm.
CN202311066386.1A 2023-08-23 2023-08-23 A topical Chinese medicinal composition for treating children chronic cough, and its preparation method Pending CN116898910A (en)

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