CN116867433A - 生物体信息测定装置、生物体信息测定方法以及程序 - Google Patents

生物体信息测定装置、生物体信息测定方法以及程序 Download PDF

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Publication number
CN116867433A
CN116867433A CN202280015154.0A CN202280015154A CN116867433A CN 116867433 A CN116867433 A CN 116867433A CN 202280015154 A CN202280015154 A CN 202280015154A CN 116867433 A CN116867433 A CN 116867433A
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CN
China
Prior art keywords
light
biological information
medium
living body
interface
Prior art date
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Pending
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CN202280015154.0A
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English (en)
Chinese (zh)
Inventor
长谷川英明
伊藤贵和
玉冈弘行
河尻幸治
黑田理人
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tohoku University NUC
Furukawa Electric Co Ltd
Original Assignee
Tohoku University NUC
Furukawa Electric Co Ltd
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Application filed by Tohoku University NUC, Furukawa Electric Co Ltd filed Critical Tohoku University NUC
Publication of CN116867433A publication Critical patent/CN116867433A/zh
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N21/4738Diffuse reflection, e.g. also for testing fluids, fibrous materials
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/06Investigating concentration of particle suspensions
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429Signal processing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429Signal processing
    • G01N15/1433Signal processing using image recognition
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0654Lenses; Optical fibres
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/16Surface properties and coatings
    • B01L2300/168Specific optical properties, e.g. reflective coatings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/06Investigating concentration of particle suspensions
    • G01N15/075Investigating concentration of particle suspensions by optical means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/06Investigating concentration of particle suspensions
    • G01N2015/0687Investigating concentration of particle suspensions in solutions, e.g. non volatile residue
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1493Particle size
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N2021/1765Method using an image detector and processing of image signal
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N21/4788Diffraction

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Signal Processing (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Optics & Photonics (AREA)
  • Food Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Ecology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Emergency Medicine (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Computer Vision & Pattern Recognition (AREA)
CN202280015154.0A 2021-02-18 2022-02-17 生物体信息测定装置、生物体信息测定方法以及程序 Pending CN116867433A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021-024344 2021-02-18
JP2021024344 2021-02-18
PCT/JP2022/006499 WO2022176965A1 (ja) 2021-02-18 2022-02-17 生体情報測定装置、生体情報測定方法、およびプログラム

Publications (1)

Publication Number Publication Date
CN116867433A true CN116867433A (zh) 2023-10-10

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CN202280015154.0A Pending CN116867433A (zh) 2021-02-18 2022-02-17 生物体信息测定装置、生物体信息测定方法以及程序

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Country Link
US (1) US20230393117A1 (https=)
EP (1) EP4296668A4 (https=)
JP (1) JPWO2022176965A1 (https=)
CN (1) CN116867433A (https=)
TW (1) TW202242408A (https=)
WO (1) WO2022176965A1 (https=)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006122579A (ja) * 2004-11-01 2006-05-18 Aime Technology Co Ltd 散乱媒質中微量成分濃度の無侵襲測定法およびその装置
CN101088003A (zh) * 2004-12-13 2007-12-12 拜尔保健有限公司 用于确定体液中被分析物的透射光谱学系统
US20140350365A1 (en) * 2011-12-19 2014-11-27 Sony Corporation Measurement device, measurement method, program and recording medium
US20170353672A1 (en) * 2016-06-07 2017-12-07 Panasonic Intellectual Property Management Co., Ltd. Imaging device provided with light source, image sensor including first accumulator and second accumulator, and controller

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6329139B1 (en) * 1995-04-25 2001-12-11 Discovery Partners International Automated sorting system for matrices with memory
JP2005106592A (ja) 2003-09-30 2005-04-21 Aime Technology Co Ltd 血糖測定法およびその装置
JP5303851B2 (ja) * 2007-04-03 2013-10-02 株式会社島津製作所 飲酒検知装置
KR101040653B1 (ko) * 2009-01-21 2011-06-10 서울대학교산학협력단 비접촉 광용적맥파 측정장치와 이를 이용한 산소포화도 측정장치 및 혈압 측정장치
CN103347550A (zh) * 2010-11-17 2013-10-09 弗雷泽纽斯医疗保健控股公司 用于光学监视系统的传感器夹组件
JP6241853B2 (ja) * 2012-12-06 2017-12-06 国立大学法人北海道大学 非侵襲型生体脂質濃度計測器、非侵襲型生体脂質代謝機能計測器、非侵襲による生体脂質濃度計測方法および非侵襲による生体脂質代謝機能検査方法
KR101512076B1 (ko) * 2014-04-29 2015-04-14 길영준 다중 생체신호를 이용한 혈당 측정 방법 및 혈당 측정 장치
US10506989B2 (en) * 2014-09-05 2019-12-17 Phc Holdings Corporation Method for quantifying glucose concentration and glucose concentration measurement device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006122579A (ja) * 2004-11-01 2006-05-18 Aime Technology Co Ltd 散乱媒質中微量成分濃度の無侵襲測定法およびその装置
CN101088003A (zh) * 2004-12-13 2007-12-12 拜尔保健有限公司 用于确定体液中被分析物的透射光谱学系统
US20140350365A1 (en) * 2011-12-19 2014-11-27 Sony Corporation Measurement device, measurement method, program and recording medium
US20170353672A1 (en) * 2016-06-07 2017-12-07 Panasonic Intellectual Property Management Co., Ltd. Imaging device provided with light source, image sensor including first accumulator and second accumulator, and controller

Also Published As

Publication number Publication date
JPWO2022176965A1 (https=) 2022-08-25
US20230393117A1 (en) 2023-12-07
EP4296668A4 (en) 2025-05-07
WO2022176965A1 (ja) 2022-08-25
EP4296668A1 (en) 2023-12-27
TW202242408A (zh) 2022-11-01

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