CN116808163B - Traditional Chinese medicine composition for clearing lung and toxin, preparation method thereof and traditional Chinese medicine and western medicine composition containing same - Google Patents

Traditional Chinese medicine composition for clearing lung and toxin, preparation method thereof and traditional Chinese medicine and western medicine composition containing same Download PDF

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CN116808163B
CN116808163B CN202310715851.3A CN202310715851A CN116808163B CN 116808163 B CN116808163 B CN 116808163B CN 202310715851 A CN202310715851 A CN 202310715851A CN 116808163 B CN116808163 B CN 116808163B
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medicine composition
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CN116808163A (en
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刘见荣
张彦亮
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Nanjing Hospital of TCM
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Nanjing Hospital of TCM
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    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233—Bupleurum
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Abstract

The invention discloses a traditional Chinese medicine composition for clearing lung and removing toxin, a preparation method thereof and a traditional Chinese medicine and western medicine composition containing the same, wherein the traditional Chinese medicine composition for clearing lung and removing toxin comprises the following raw materials in parts by weight: 8-12 parts of bupleurum chinense, 5-7 parts of wine baical skullcap root, 7-11 parts of ginger processed pinellia tuber, 2-4 parts of dried ginger, 8-12 parts of pilose asiabell root, 13-17 parts of Chinese date, 8-12 parts of raw liquorice, 10-14 parts of radix isatidis, 13-17 parts of dandelion, 7-11 parts of blackberry lily, 7-11 parts of fried bitter apricot kernel, 10-14 parts of aster melitensis, 10-14 parts of honey coltsfoot flower, 13-17 parts of gypsum and 2-4 parts of Chinese ephedra. The traditional Chinese medicine composition for clearing lung and removing toxin is reasonably matched according to the traditional Chinese medicine compatibility, is green and environment-friendly, has obvious treatment or alleviation effects on symptoms such as fever, pharyngalgia and cough caused by bacterial infection, influenza A, new crown and the like, and is not easy to repeat; no toxic side effect.

Description

Traditional Chinese medicine composition for clearing lung and toxin, preparation method thereof and traditional Chinese medicine and western medicine composition containing same
Technical Field
The invention relates to a traditional Chinese medicine composition for clearing lung-heat and toxin, a preparation method thereof and a traditional Chinese medicine composition and a western medicine composition containing the traditional Chinese medicine composition, and belongs to the technical field of antipyretic, sore-throat relieving and cough relieving medicines.
Background
The body temperature of normal people is regulated by the temperature regulating center, and the heat generating and radiating processes are dynamically balanced by the nerve and body fluid factors, so that the body temperature is kept in a relatively constant range. Fever refers to the condition in which pyrogens directly act on the thermoregulation center, dysfunction of the thermoregulation center or excessive heat production and heat dissipation decrease caused by various reasons, resulting in an increase in body temperature beyond the normal range.
The normothermia of each individual is slightly different and is also affected by factors such as time, season, environment, menstruation, etc. Typically, normothermia is between 36 and 37 ℃. It is preferable to determine whether or not the body temperature is generated, and to compare the body temperature with the body temperature under the same conditions as the normal times. If the own normal body temperature is unknown, armpit body temperature (5-10 minutes of detection) exceeding 37.4 ℃ can be defined as fever.
Upper respiratory tract infections caused by bacterial infection, influenza a virus infection (a-stream), novel coronavirus infection (new crown), etc. often cause fever, accompanied by symptoms of pain, pharyngalgia, cough, etc. of different degrees throughout the body. If western medicines are used singly for treatment, the possibility of repeated heating is extremely high, especially in at least 48 hours, and antipyretics (acetaminophen and ibuprofen) are required to be repeatedly matched for antipyretic; in addition, the nail flow is more likely to generate high fever, and is harder to defer, and the high fever is easy to repeatedly occur or continuously occur within 48-72 hours.
Disclosure of Invention
The invention provides a traditional Chinese medicine composition for clearing lung and toxin, a preparation method thereof and a traditional Chinese medicine composition containing the same, which have obvious treatment or alleviation effects on fever, pharyngalgia, cough and other symptoms caused by bacterial infection, influenza A, new crown and the like, are not easy to repeat and reduce the times of using antipyretics.
In order to solve the technical problems, the technical scheme adopted by the invention is as follows:
A traditional Chinese medicine composition for clearing lung and toxin, which comprises the following raw materials: 8-12 parts of bupleurum chinense, 5-7 parts of wine baical skullcap root, 7-11 parts of ginger processed pinellia tuber, 2-4 parts of dried ginger, 8-12 parts of pilose asiabell root, 13-17 parts of Chinese date, 8-12 parts of raw liquorice, 10-14 parts of radix isatidis, 13-17 parts of dandelion, 7-11 parts of blackberry lily, 7-11 parts of fried bitter apricot kernel, 10-14 parts of aster melitensis, 10-14 parts of honey coltsfoot flower, 13-17 parts of gypsum and 2-4 parts of Chinese ephedra.
The traditional Chinese medicine composition for clearing lung-heat and toxin is also a traditional Chinese medicine for relieving fever, sore throat and cough, and has obvious curative effects on patients with middle heat, high heat and the like.
In order to further promote antipyresis and relieve symptoms, the raw material components of the lung-heat clearing and toxin-vanquishing drink traditional Chinese medicine composition also comprise: 7-11 parts of platycodon grandiflorum, which is added into the composition and has the effects of relieving sore throat, relieving pain and ventilating lung.
In order to further promote antipyresis and relieve symptoms, the raw material components of the lung-heat clearing and toxin-vanquishing drink traditional Chinese medicine composition also comprise: 7-11 parts of sweet wormwood herb. The addition of the sweet wormwood has the effects of promoting heat clearing, detoxifying and bringing down a fever.
As an optimal implementation scheme, the traditional Chinese medicine composition for clearing lung and removing toxicity comprises the following raw materials: 10 parts of radix bupleuri, 6 parts of wine radix scutellariae, 9 parts of ginger processed pinellia, 3 parts of dried ginger, 10 parts of radix codonopsis, 15 parts of jujube, 10 parts of raw liquorice, 9 parts of sweet wormwood herb, 12 parts of radix isatidis, 15 parts of dandelion, 9 parts of blackberry lily, 9 parts of platycodon grandiflorum, 9 parts of fried bitter apricot seed, 12 parts of aster, 12 parts of honey coltsfoot flower, 15 parts of gypsum and 3 parts of honey ephedra herb.
The prescription is prepared from the small bupleurum decoction, the Hema apricot stone Gaultheria decoction, the sweet wormwood herb, the radix isatidis and the dandelion, and has the functions of clearing heat, detoxicating and reducing fever; adding rhizoma Belamcandae, radix Asteris, flos Farfarae, and flos Farfarae for warming lung, resolving phlegm, relieving cough, and relieving sore throat; radix Platycodi and semen Armeniacae amarum are combined with dispersing lung qi and descending qi to strengthen the dispersing and descending of lung.
The Xiao chai Hu Tang can relieve shaoyang, treat cold and shaoyang syndrome, and is mainly used for treating cold and heat, bitter taste in chest and hypochondrium, inappetence, vexation, vomiting, bitter taste in mouth, dry throat, dizzy, white coating and wiry pulse. In the recipe, bupleurum root is bitter and flat, enters liver and gall meridian, is a special medicine for treating shaoyang meridian, and is a monarch medicine for dispelling pathogenic factors from the surface of shaoyang half and dispersing stagnation of shaoyang qi; the radix scutellariae is bitter and cold, clears heat in the shaoyang half interior and is used as a ministerial drug; the gallbladder qi affecting the stomach and the stomach qi failing to descend, the pinellia tuber and the ginger are added for harmonizing the stomach and descending the adverse qi and preventing vomiting, and the ginger is also used for preparing the pinellia tuber toxin to assist the pinellia tuber in harmonizing the stomach; the pathogenic factors enter the shaoyang and are caused by the deficiency of the healthy qi, so the dangshen and the Chinese date are added to replenish qi and invigorate the spleen, so that the healthy qi is strengthened to eliminate the pathogenic factors, and the pathogenic factors are defended from being transmitted internally; prepared licorice root, radix Glycyrrhizae Praeparata helps the body resistance of the patient and jujube, and can regulate the functions of the other drugs. Some patients with influenza are accompanied with nausea and vomiting or spleen and stomach function weakness in normal times, and the above medicines are combined to mainly treat shaoyang and stomach qi, so that pathogenic qi is relieved, the machine is beneficial, and stomach qi is harmonized, so that symptoms are self-removed. The Ma xing Shi Gan Tang is pungent and cool and has the effects of dispersing and releasing, clearing lung and relieving asthma, and is a main formula for treating asthma caused by exogenous wind-cold and stagnated heat; the main indications are: exogenous pathogenic wind, indigenous heat, cough and dyspnea, rapid nasal fan, thirst, sweating or no sweat, thin white or yellow tongue coating, and superficial and rapid pulse. If the exterior syndrome is still present, ma Huang is used to ventilate the lung to disperse the cold in the exterior. Sweats and dyspnea are forced by internal heat, so gypsum is used for clearing lung heat and clearing internal heat, and ephedra is compatible with gypsum Xin Lianggan for moistening and clearing lung heat; the almond is supplemented with ephedra herb to relieve asthma; licorice root, radix Glycyrrhizae Praeparata helps the gypsum to promote the production of body fluid; so far, the interior heat is clear, and the exterior evil is relieved, so that sweat can be stopped and asthma can be relieved. The raw licorice has the effects of detoxification, phlegm elimination, pain relief and spasmolysis, and the sore throat of the influenza patient is obvious, the method uses 10g of raw licorice and is matched with platycodon grandiflorum to strengthen sore throat and relieve pain; clinically, patients suffering from influenza or bacterial infection are frequently high in fever, and sweet wormwood herb is used for clearing deficiency heat, removing bone steaming, relieving summer heat and checking malaria; radix Isatidis has effects of clearing heat and detoxicating, cooling blood, relieving sore throat; dandelion: clearing away heat and toxic materials, promoting urination and resolving hard mass; the three components cooperate to strengthen the efficacy of clearing heat, detoxicating and bringing down a fever. Cough is caused in the middle and later period of patients suffering from influenza or bacterial infection, wherein lung qi is released by ephedra and platycodon grandiflorum, qi is reduced by almond, blackberry lily, aster and coltsfoot flower are added to warm lung, resolve phlegm and relieve cough and relieve sore throat so as to strengthen the release and drop of lung, and the cough and phlegm reducing effect is enhanced by matching with raw licorice root.
As a preferred implementation scheme, the lung-heat clearing and toxin-vanquishing drink traditional Chinese medicine composition comprises the following raw material components: 8 parts of radix bupleuri, 7 parts of wine radix scutellariae, 7 parts of ginger processed pinellia tuber, 4 parts of dried ginger, 8 parts of radix codonopsis pilosulae, 15 parts of Chinese date, 12 parts of raw liquorice, 7 parts of sweet wormwood herb, 14 parts of radix isatidis, 13 parts of dandelion, 11 parts of blackberry lily, 7 parts of platycodon grandiflorum, 11 parts of fried bitter apricot seed, 10 parts of aster, 14 parts of honey coltsfoot flower, 15 parts of gypsum and 2 parts of honey ephedra herb.
As a preferred implementation scheme, the lung-heat clearing and toxin-vanquishing drink traditional Chinese medicine composition comprises the following raw material components: 12 parts of radix bupleuri, 5 parts of wine radix scutellariae, 11 parts of ginger processed pinellia, 2 parts of dried ginger, 12 parts of radix codonopsis, 15 parts of jujube, 8 parts of raw liquorice, 11 parts of sweet wormwood herb, 10 parts of radix isatidis, 17 parts of dandelion, 11 parts of blackberry lily, 11 parts of platycodon grandiflorum, 7 parts of fried bitter apricot seed, 14 parts of aster, 10 parts of honey coltsfoot flower, 15 parts of gypsum and 4 parts of honey ephedra herb.
The preparation method of the traditional Chinese medicine composition for clearing lung and removing toxin comprises the following steps: decocting in casserole, adding Gypsum Fibrosum into casserole, adding water, boiling with strong fire, and decocting with slow fire for 20 min; adding water to other medicinal materials until the water level exceeds 2-3 cm, soaking for 20-30 min, pouring into a gypsum pot, decocting twice, boiling with strong fire for the 1 st time, decocting with slow fire for 20-30 min, and pouring out medicinal liquid after one decoction is finished; adding water again to water level 1-2 cm higher than the water level of the medicinal materials (the medicinal materials remained after the decoction is poured out after the first decoction), boiling with strong fire, decocting with slow fire for 15 min, pouring out the medicinal materials after the second decoction, and mixing the medicinal materials poured out for 2 times to obtain the decoction.
As another preparation method of the traditional Chinese medicine composition for clearing lung and removing toxin, the preparation method comprises the following steps:
(1) Mixing all the medicinal materials, adding water at 40-50 ℃ for soaking for 20-30 min, then carrying out reflux extraction for 4-5 hours, filtering, and concentrating the filtrate to 1.5-2.5 times of the total weight of the Chinese medicinal materials to obtain an extracting solution;
(2) Soaking the filter residue obtained in the step (1) in ethanol for 20-30 min, then extracting for 2-3 h under reflux, filtering, concentrating the filtrate, spray drying, pulverizing to obtain powder, and adding the powder into the extracting solution of the step (1) to be uniformly mixed to obtain the product.
By the method, the effective components in the traditional Chinese medicine composition can be more effectively utilized, and the curative effect is more obvious.
The ethanol is 75% ethanol.
A Chinese and western medicine composition for treating influenza A virus infection (A flow), novel coronavirus infection (new crown) or bacterial infection comprises the Chinese medicine composition for clearing lung and removing toxin, and also comprises oseltamivir, alzvudine, minoxidil, faviravir or antibiotics. Experiments show that, aiming at the infection of the first class, the new crown or the bacteria, the Chinese medicines and the western medicines are matched, so that the antipyretic time can be effectively accelerated, the symptom can be accelerated to be improved, and the side effects of the western medicines can be reduced.
The technology not mentioned in the present invention refers to the prior art.
The traditional Chinese medicine composition for clearing lung and removing toxin is reasonably matched according to the traditional Chinese medicine compatibility, is green and environment-friendly, has obvious treatment or alleviation effects on symptoms such as fever, pharyngalgia and cough caused by bacterial infection, influenza A, new crown and the like, and is not easy to repeat; no toxic side effect.
Detailed Description
For a better understanding of the present invention, the following examples are further illustrated, but are not limited to the following examples.
Example 1
A traditional Chinese medicine composition for clearing lung and toxin, which comprises the following raw materials: 10g of bupleurum chinense, 6g of wine-processed radix scutellariae, 9g of ginger processed pinellia tuber, 3g of dried ginger, 10g of radix codonopsis pilosulae, 15g of Chinese date, 10g of raw liquorice, 9g of sweet wormwood herb, 12g of radix isatidis, 15g of dandelion, 9g of blackberry lily, 9g of platycodon root, 9g of fried bitter apricot seed, 12g of aster, 12g of honey coltsfoot flower, 15g of gypsum and 3g of honey ephedra herb.
Example 2
A traditional Chinese medicine composition for clearing lung and toxin, which comprises the following raw materials: 8g of radix bupleuri, 7g of wine radix scutellariae, 7g of ginger processed pinellia tuber, 4g of dried ginger, 8g of radix codonopsis pilosulae, 15g of Chinese date, 12g of raw liquorice, 7g of sweet wormwood herb, 14g of radix isatidis, 13g of dandelion, 11g of blackberry lily, 7g of platycodon root, 11g of fried bitter apricot seed, 10g of aster, 14g of honey coltsfoot flower, 15g of gypsum and 2g of honey ephedra herb.
Example 3
A traditional Chinese medicine composition for clearing lung and toxin, which comprises the following raw materials: 12g of bupleurum chinense, 5g of wine-processed radix scutellariae, 11g of ginger processed pinellia tuber, 2g of dried ginger, 12g of radix codonopsis pilosulae, 15g of Chinese date, 8g of raw liquorice, 11g of sweet wormwood herb, 10g of radix isatidis, 17g of dandelion, 11g of blackberry lily, 11g of platycodon root, 7g of fried bitter apricot seed, 14g of aster, 10g of honey coltsfoot flower, 15g of gypsum and 4g of honey ephedra.
Example 4
A traditional Chinese medicine composition for clearing lung and toxin, which comprises the following raw materials: 10g of bupleurum chinense, 6g of wine-processed radix scutellariae, 9g of ginger processed pinellia tuber, 3g of dried ginger, 10g of radix codonopsis pilosulae, 15g of jujube, 10g of raw licorice, 9g of sweet wormwood herb, 12g of radix isatidis, 15g of dandelion, 9g of blackberry lily, 9g of fried bitter apricot seed, 12g of aster, 12g of honey coltsfoot flower, 15g of gypsum and 3g of honey ephedra herb. This example differs from example 1 in that it does not contain platycodon root.
Example 5
A traditional Chinese medicine composition for clearing lung and toxin, which comprises the following raw materials: 10g of bupleurum chinense, 6g of wine-processed radix scutellariae, 9g of ginger processed pinellia tuber, 3g of dried ginger, 10g of radix codonopsis pilosulae, 15g of jujube, 10g of raw licorice, 12g of radix isatidis, 15g of dandelion, 9g of blackberry lily, 9g of platycodon root, 9g of fried bitter apricot seed, 12g of aster, 12g of honey coltsfoot flower, 15g of gypsum and 3g of honey ephedra. This example differs from example 1 in that it does not contain sweet wormwood.
Comparative example 1
A traditional Chinese medicine composition for clearing lung and toxin, which comprises the following raw materials: 10g of bupleurum chinense, 6g of wine baical skullcap root, 9g of ginger processed pinellia tuber, 3g of dried ginger, 10g of pilose asiabell root, 15g of Chinese date, 9g of sweet wormwood herb, 12g of radix isatidis, 15g of dandelion, 9g of blackberry lily, 9g of platycodon root, 9g of fried bitter apricot seed, 12g of aster, 12g of honey coltsfoot flower, 15g of gypsum and 3g of honey ephedra herb. This example differs from example 1 in that it does not contain raw licorice.
Comparative example 2
A traditional Chinese medicine composition for clearing lung and toxin, which comprises the following raw materials: 10g of radix bupleuri, 6g of wine radix scutellariae, 9g of ginger processed pinellia tuber, 3g of dried ginger, 10g of radix codonopsis pilosulae, 15g of jujube, 10g of raw licorice, 9g of sweet wormwood herb, 12g of radix isatidis, 15g of dandelion, 9g of platycodon root, 9g of fried bitter apricot seed, 15g of gypsum and 3g of ephedra herb. This example differs from example 1 in that it does not contain blackberry lily, aster melittifolium and coltsfoot flower.
The traditional Chinese medicine composition for clearing lung and toxin is prepared by the following two methods:
Method 1:
Decocting in marmite, adding Gypsum Fibrosum into marmite, adding water, boiling with strong fire, and decocting with slow fire for 25 min; adding water to the other medicinal materials until the water level exceeds 2 cm, soaking for 25 min, pouring into a gypsum pot, decocting twice, boiling with strong fire for 1 st time, decocting with slow fire for 25 min, and pouring out medicinal liquid after the decoction is finished; adding water again until the water level exceeds 1 cm, boiling with strong fire, decocting with slow fire for 15min, pouring out the decoction, mixing the 2 decoctions, and taking twice in the morning and afternoon.
Method 2:
(1) Mixing all the medicinal materials, adding water at 40-50 ℃ for soaking for 25min, wherein the amount of the soaked water is 3 times of the total weight of the Chinese medicinal materials, adding water 5 times of the total weight of the Chinese medicinal materials again after soaking, carrying out reflux extraction for 5 hours at 98 ℃, filtering, and concentrating the filtrate to 2 times of the total weight of the Chinese medicinal materials to obtain an extracting solution;
(2) Soaking the filter residue obtained in the step (1) with 75% ethanol for 25min, wherein the dosage of the soaked ethanol is 3 times of the weight of the filter residue, adding ethanol which is 5 times of the weight of the filter residue again after the soaking is finished, reflux-extracting for 2-3 h at 80 ℃, filtering, concentrating the filtrate until the relative density is 1, spray-drying, crushing to obtain powder, recovering the distilled ethanol while concentrating, adding the powder into the extracting solution of the step (1), uniformly mixing, and taking twice in the morning and afternoon.
Clinical experiments:
the administration method comprises the following steps: the preparation is administered orally 2 times a day, 1 time each in the morning and afternoon, once in 9 am and once in 3 pm for 5 days.
And (3) statistical treatment:
1. For patients with fever (bacterial infection) as the primary disease, the symptoms are: the fever is carried out for 1 day, the body temperature is higher than 38 ℃, headache, hypodynamia, pharyngalgia, general ache and slight dry cough are caused, 50 patients are treated by adopting various cases of traditional Chinese medicine mixture, the symptom distribution and age distribution of each case of patients are the same, no statistical difference exists, and the body temperature is reduced to the normal temperature of human body, and the result is as follows:
In the above table, no repeated fever is indicated, which means that there is no fever again after the first fever reduction. Each example did not show any toxic or side effects during the administration period.
2. For patients with fever (new crown) as the primary disease, the symptoms are: fever is caused for 1 day, the body temperature is higher than 38 ℃, and the symptoms of headache, hypodynamia, pharyngalgia, cough, white phlegm, nasal obstruction, clear nasal discharge and positive new crown antigen are caused; the traditional Chinese medicine mixture is used for treatment, 50 patients are treated in each case, the symptom distribution and the age distribution of each patient are the same, no statistical difference exists, and the temperature of the human body is reduced to the normal temperature, so that the human body is treated as defervescence, and the result is as follows:
3. For patients with fever (positive for nail flow) as the primary disease, the symptoms are: the fever is carried out for 1 day, the body temperature is higher than 38 ℃, slight headache, hypodynamia, knee joint ache of lower limb, dry throat pain, occasional dry cough, nasal obstruction and clear nasal discharge are carried out, 50 patients are treated in each case, the symptom distribution and age distribution of each patient are the same, no statistical difference exists, and the body temperature is reduced to the normal temperature of human body, and the result is as follows:
In the above table, the agent of example 1 was prepared by method 2. Oseltamivir (capsule, 75mg once, twice daily) was orally administered for the preparation of acetaminophen (body temperature exceeding 38.5 degrees, 1 granule temporarily). The traditional Chinese medicine composition has good curative effect on the nail flow, can completely abate fever within 24 hours, is counted, relieves uncomfortable symptoms gradually, and is basically cured by the 5 th day without uncomfortable symptoms, repeated fever and negative nail flow detection; after the traditional Chinese medicine composition is matched with oseltamivir for use, the antipyretic effect can be effectively promoted, the alleviation of symptoms is accelerated, the frequency of using acetaminophen is reduced, antipyretic patients are basically healed in 3-4 days, uncomfortable symptoms and repeated fever are avoided, and the nail flow detection is negative in 5 days.
Typical cases (in the table "-" indicates antipyresis, body temperature recovery normal):
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Claims (9)

1. A pharmaceutical composition for treating influenza a virus infection, comprising: the Chinese and western medicine composition consists of a Chinese medicine composition and western medicines, wherein the western medicine is oseltamivir or famciclovir; the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 8-12 parts of radix bupleuri, 5-7 parts of radix scutellariae preparata, 7-11 parts of ginger processed pinellia, 2-4 parts of dried ginger, 8-12 parts of radix codonopsis pilosulae, 13-17 parts of Chinese date, 8-12 parts of raw liquorice, 10-14 parts of radix isatidis, 13-17 parts of dandelion, 7-11 parts of blackberry lily, 7-11 parts of fried bitter apricot kernel, 10-14 parts of aster, 10-14 parts of honey coltsfoot flower, 13-17 parts of gypsum, 2-4 parts of honey ephedra, 7-11 parts of platycodon grandiflorum and 7-11 parts of sweet wormwood herb.
2. A pharmaceutical composition for treating a novel coronavirus infection, comprising: the Chinese and western medicine composition consists of a Chinese medicine composition and western medicines, wherein the western medicine is one of an alzvudine tablet or a minoxidil tablet/ritonavir tablet; the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 8-12 parts of radix bupleuri, 5-7 parts of radix scutellariae preparata, 7-11 parts of ginger processed pinellia, 2-4 parts of dried ginger, 8-12 parts of radix codonopsis pilosulae, 13-17 parts of Chinese date, 8-12 parts of raw liquorice, 10-14 parts of radix isatidis, 13-17 parts of dandelion, 7-11 parts of blackberry lily, 7-11 parts of fried bitter apricot kernel, 10-14 parts of aster, 10-14 parts of honey coltsfoot flower, 13-17 parts of gypsum, 2-4 parts of honey ephedra, 7-11 parts of platycodon grandiflorum and 7-11 parts of sweet wormwood herb.
3. A pharmaceutical composition for treating bacterial infection, characterized in that: the Chinese and western medicine composition consists of a Chinese medicine composition and western medicines, wherein the western medicines are antibiotics; the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 8-12 parts of radix bupleuri, 5-7 parts of radix scutellariae preparata, 7-11 parts of ginger processed pinellia, 2-4 parts of dried ginger, 8-12 parts of radix codonopsis pilosulae, 13-17 parts of Chinese date, 8-12 parts of raw liquorice, 10-14 parts of radix isatidis, 13-17 parts of dandelion, 7-11 parts of blackberry lily, 7-11 parts of fried bitter apricot kernel, 10-14 parts of aster, 10-14 parts of honey coltsfoot flower, 13-17 parts of gypsum, 2-4 parts of honey ephedra, 7-11 parts of platycodon grandiflorum and 7-11 parts of sweet wormwood herb.
4. A pharmaceutical composition according to any one of claims 1 to 3, wherein: the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 10 parts of radix bupleuri, 6 parts of wine radix scutellariae, 9 parts of ginger processed pinellia tuber, 3 parts of dried ginger, 10 parts of radix codonopsis pilosulae, 15 parts of Chinese date, 10 parts of raw liquorice, 9 parts of sweet wormwood herb, 12 parts of radix isatidis, 15 parts of dandelion, 9 parts of blackberry lily, 9 parts of platycodon grandiflorum, 9 parts of fried bitter apricot seed, 12 parts of aster, 12 parts of honey coltsfoot flower, 15 parts of gypsum and 3 parts of honey ephedra.
5. A pharmaceutical composition according to any one of claims 1 to 3, wherein: the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 8 parts of radix bupleuri, 7 parts of wine radix scutellariae, 7 parts of ginger processed pinellia tuber, 4 parts of dried ginger, 8 parts of radix codonopsis pilosulae, 15 parts of Chinese date, 12 parts of raw liquorice, 7 parts of sweet wormwood herb, 14 parts of radix isatidis, 13 parts of dandelion, 11 parts of blackberry lily, 7 parts of platycodon grandiflorum, 11 parts of fried bitter apricot seed, 10 parts of aster, 14 parts of honey coltsfoot flower, 15 parts of gypsum and 2 parts of honey ephedra.
6. A pharmaceutical composition according to any one of claims 1 to 3, wherein: the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 12 parts of radix bupleuri, 5 parts of wine radix scutellariae, 11 parts of ginger processed pinellia, 2 parts of dried ginger, 12 parts of radix codonopsis, 15 parts of jujube, 8 parts of raw liquorice, 11 parts of sweet wormwood herb, 10 parts of radix isatidis, 17 parts of dandelion, 11 parts of blackberry lily, 11 parts of platycodon grandiflorum, 7 parts of fried bitter apricot seed, 14 parts of aster, 10 parts of honey coltsfoot flower, 15 parts of gypsum and 4 parts of honey ephedra.
7. A pharmaceutical composition according to any one of claims 1 to 3, wherein: the preparation method of the traditional Chinese medicine composition comprises the following steps: decocting with marmite, and decocting Gypsum Fibrosum with slow fire for 20 min after boiling with strong fire; adding water to other medicinal materials until the water level exceeds 2-3 cm of the medicinal materials, soaking for 20-30 minutes, pouring into a gypsum pot, decocting twice, boiling with strong fire for the 1 st time, decocting with slow fire for 20-30 minutes, and pouring out medicinal juice after the first decoction is finished; adding water again to water level of 1-2 cm above the medicinal materials, boiling with strong fire, decocting with slow fire for 15 min, decocting again, pouring out medicinal liquid, and mixing the two decoctions to obtain decoction.
8. A pharmaceutical composition according to any one of claims 1 to 3, wherein: the preparation method of the traditional Chinese medicine composition comprises the following steps:
(1) Mixing all the medicinal materials, adding water at 40-50 ℃ for soaking for 20-30 min, then carrying out reflux extraction for 4-5 hours, filtering, and concentrating the filtrate to 1.5-2.5 times of the total weight of the Chinese medicinal materials to obtain an extracting solution;
(2) Soaking the filter residue obtained in the step (1) in ethanol for 20-30 min, then extracting for 2-3 h under reflux, filtering, concentrating the filtrate, spray-drying, pulverizing to obtain powder, and adding the powder into the extracting solution in the step (1) to be uniformly mixed to obtain the product.
9. The pharmaceutical composition of claim 8, wherein: ethanol is 75% ethanol.
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